WO2010144128A3 - Molecular alignment and attachment of nucleic acid molecules - Google Patents

Molecular alignment and attachment of nucleic acid molecules Download PDF

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Publication number
WO2010144128A3
WO2010144128A3 PCT/US2010/001648 US2010001648W WO2010144128A3 WO 2010144128 A3 WO2010144128 A3 WO 2010144128A3 US 2010001648 W US2010001648 W US 2010001648W WO 2010144128 A3 WO2010144128 A3 WO 2010144128A3
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WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
attachment
molecular alignment
methods
Prior art date
Application number
PCT/US2010/001648
Other languages
French (fr)
Other versions
WO2010144128A2 (en
Inventor
Katelyn Marie Murtagh
Original Assignee
Zs Genetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zs Genetics, Inc. filed Critical Zs Genetics, Inc.
Publication of WO2010144128A2 publication Critical patent/WO2010144128A2/en
Publication of WO2010144128A3 publication Critical patent/WO2010144128A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention includes methods of performing molecular alignment of nucleic acid molecules and methods of attaching nucleic acid molecules to a substrate.
PCT/US2010/001648 2009-06-08 2010-06-08 Molecular alignment and attachment of nucleic acid molecules WO2010144128A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26804209P 2009-06-08 2009-06-08
US61/268,042 2009-06-08

Publications (2)

Publication Number Publication Date
WO2010144128A2 WO2010144128A2 (en) 2010-12-16
WO2010144128A3 true WO2010144128A3 (en) 2011-05-12

Family

ID=43309403

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/001648 WO2010144128A2 (en) 2009-06-08 2010-06-08 Molecular alignment and attachment of nucleic acid molecules

Country Status (1)

Country Link
WO (1) WO2010144128A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014078652A1 (en) 2012-11-16 2014-05-22 Zs Genetics, Inc. Heavy atom labeled nucleosides, nucleotides, and nucleic acid polymers, and uses thereof
WO2017075179A1 (en) 2015-10-27 2017-05-04 Zs Genetics, Inc. Sequencing by deconvolution

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303296B1 (en) * 1994-02-11 2001-10-16 Institut Pasteur Centre National De La Recherche Scientifique Process for aligning macromolecules by passage of a meniscus and applications
US20070072193A1 (en) * 2005-09-27 2007-03-29 Shah Manish M Ligand arrays having controlled feature size, and methods of making and using the same
WO2007049280A1 (en) * 2005-10-26 2007-05-03 Ramot At Tel-Aviv University Ltd Method and device for wettability modification of materials

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303296B1 (en) * 1994-02-11 2001-10-16 Institut Pasteur Centre National De La Recherche Scientifique Process for aligning macromolecules by passage of a meniscus and applications
US20070072193A1 (en) * 2005-09-27 2007-03-29 Shah Manish M Ligand arrays having controlled feature size, and methods of making and using the same
WO2007049280A1 (en) * 2005-10-26 2007-05-03 Ramot At Tel-Aviv University Ltd Method and device for wettability modification of materials

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ALLEMAND, J. F. ET AL.: "pH-dependent specific binding and combing of DNA", BIOPHYSICAL JOURNAL., vol. 73, no. 4, October 1997 (1997-10-01), pages 2064 - 2070, XP002974837 *

Also Published As

Publication number Publication date
WO2010144128A2 (en) 2010-12-16

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