WO2010122571A3 - A process for the selective methylation of erythromycin a derivatives. - Google Patents

A process for the selective methylation of erythromycin a derivatives. Download PDF

Info

Publication number
WO2010122571A3
WO2010122571A3 PCT/IN2010/000226 IN2010000226W WO2010122571A3 WO 2010122571 A3 WO2010122571 A3 WO 2010122571A3 IN 2010000226 W IN2010000226 W IN 2010000226W WO 2010122571 A3 WO2010122571 A3 WO 2010122571A3
Authority
WO
WIPO (PCT)
Prior art keywords
erythromycin
derivatives
selective methylation
methylation
selective
Prior art date
Application number
PCT/IN2010/000226
Other languages
French (fr)
Other versions
WO2010122571A2 (en
Inventor
Rajiv Sakhardande
Manmohan Nimbalkar
Rajan Ramalingam
Sunil Uttarwar
Gautam Wani
Subarao Patil
Sandip Khilari
Rohidas Mhaske
Baban Gharge
Original Assignee
Elder Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elder Pharmaceuticals Ltd. filed Critical Elder Pharmaceuticals Ltd.
Publication of WO2010122571A2 publication Critical patent/WO2010122571A2/en
Publication of WO2010122571A3 publication Critical patent/WO2010122571A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)

Abstract

A process for selective methylation at 6 position of erythromycin A derivatives.
PCT/IN2010/000226 2009-04-23 2010-04-07 A process for the selective methylation of erythromycin a derivatives. WO2010122571A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1087/MUM/2009 2009-04-23
IN1087MU2009 2009-04-23

Publications (2)

Publication Number Publication Date
WO2010122571A2 WO2010122571A2 (en) 2010-10-28
WO2010122571A3 true WO2010122571A3 (en) 2011-01-06

Family

ID=43011547

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2010/000226 WO2010122571A2 (en) 2009-04-23 2010-04-07 A process for the selective methylation of erythromycin a derivatives.

Country Status (1)

Country Link
WO (1) WO2010122571A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260938A2 (en) * 1986-09-18 1988-03-23 Taisho Pharmaceutical Co. Ltd Erythromycin A derivatives and method for preparing the same
EP0272110A2 (en) * 1986-12-17 1988-06-22 Taisho Pharmaceutical Co. Ltd Erythromycin a derivatives and method for the preparation of the same
WO2001087807A2 (en) * 2000-05-15 2001-11-22 Ranbaxy Laboratories Limited A cost effective method for selective methylation of erythromycin a derivatives
WO2006100691A2 (en) * 2005-03-23 2006-09-28 Ind-Swift Laboratories Limited A process for the preparation of 6-o-methyl erythromycin a derivative

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0260938A2 (en) * 1986-09-18 1988-03-23 Taisho Pharmaceutical Co. Ltd Erythromycin A derivatives and method for preparing the same
EP0272110A2 (en) * 1986-12-17 1988-06-22 Taisho Pharmaceutical Co. Ltd Erythromycin a derivatives and method for the preparation of the same
WO2001087807A2 (en) * 2000-05-15 2001-11-22 Ranbaxy Laboratories Limited A cost effective method for selective methylation of erythromycin a derivatives
WO2006100691A2 (en) * 2005-03-23 2006-09-28 Ind-Swift Laboratories Limited A process for the preparation of 6-o-methyl erythromycin a derivative

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MASTER, H. ET AL.: "A regioselective alkylation at the C-6 hydroxyl group of erythromycin A-oxime derivatives", JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, vol. 70, no. 10, 2005, pages 1147 - 1153 *

Also Published As

Publication number Publication date
WO2010122571A2 (en) 2010-10-28

Similar Documents

Publication Publication Date Title
ZA201202988B (en) Azole derivatives, methods for producing the same, intermediate thereof, agro-horticultural agents
HK1158628A1 (en) Process for preparing dihydropteridinone derivatives
IL201973A0 (en) 3,3-spiroindolinone derivatives
IL206765A0 (en) 4,5-dihydro-oxazol-2-yl-amine derivatives
IL216826A0 (en) Pyridil-triazine derivatives, compositions comprising the same and processes for producing the same
AP2012006216A0 (en) Benzimidazole-imidazole derivatives.
HK1143373A1 (en) Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives 5--45-
HK1133037A1 (en) Macrolide derivative
ZA201001797B (en) 1,1,1-trifluoro-2-hydroxy-3-phenylpropane derivatives
PL2213654T3 (en) Process for preparing 2-amino-5-bromobenzamide derivatives
HRP20130678T1 (en) Feeder for robots, automation means and the like
ZA201204135B (en) 3,4,4a,10b-tetrahydro-1h-thiopyrano-[4.3-c]isoquinoline derivatives
ZA201002217B (en) 1,3-dihydroisoindole derivatives
HK1142888A1 (en) Macrolactone derivatives
EP2202231A4 (en) 2,3-dihydroiminoisoindole derivative
IL200103A0 (en) A macrolide solid form and processes for producing the same
ZA200806840B (en) Improved process for producing nitroisourea derivatives
GB2476643B (en) 1,4-Dihydro-1,4-dioxonaphtalene derivatives as anticoagulants
ZA201106360B (en) Method for manufacturing 1,5-benzodiazepine derivative
IL202016A0 (en) Process for the preparation of dibenzo [b,d]azepin-6-one derivative
GB2443410B (en) A process for the preparation of 6-bromo-6-deoxy-2,3-anhydro-D-manno-1,4-lactone
WO2010122571A3 (en) A process for the selective methylation of erythromycin a derivatives.
IL186174A0 (en) A process for the preparation of 6-0-methyl erythromycin a derivative
ZA200905543B (en) High-dose, long-acting ectoparasiticide for extended control
HU0900616D0 (en) 2,3,4-benzodiazepine-2,2-dioxide derivatives

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10766749

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10766749

Country of ref document: EP

Kind code of ref document: A2