WO2010107204A3 - 나노 입자 흡입 독성 평가용 노출 챔버 장치 - Google Patents

나노 입자 흡입 독성 평가용 노출 챔버 장치 Download PDF

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Publication number
WO2010107204A3
WO2010107204A3 PCT/KR2010/001503 KR2010001503W WO2010107204A3 WO 2010107204 A3 WO2010107204 A3 WO 2010107204A3 KR 2010001503 W KR2010001503 W KR 2010001503W WO 2010107204 A3 WO2010107204 A3 WO 2010107204A3
Authority
WO
WIPO (PCT)
Prior art keywords
assessing
nanoparticles
inhalation toxicity
exposure chamber
chamber apparatus
Prior art date
Application number
PCT/KR2010/001503
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English (en)
French (fr)
Other versions
WO2010107204A2 (ko
Inventor
안강호
Original Assignee
(주)에이치시티
권용택
최정석
윤진욱
전기수
조재호
이재성
유일재
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by (주)에이치시티, 권용택, 최정석, 윤진욱, 전기수, 조재호, 이재성, 유일재 filed Critical (주)에이치시티
Publication of WO2010107204A2 publication Critical patent/WO2010107204A2/ko
Publication of WO2010107204A3 publication Critical patent/WO2010107204A3/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A61D7/04—Devices for anaesthetising animals by gases or vapours; Inhaling devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
    • G01N1/2214—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling by sorption
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N37/00—Details not covered by any other group of this subclass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Housing For Livestock And Birds (AREA)
  • Exposure And Positioning Against Photoresist Photosensitive Materials (AREA)

Abstract

본 발명은 나노 입자 흡입 독성 평가용 노출 챔버 장치에 관한 것으로, 실험 동물이 나노 입자에 노출되도록 형성된 노출 챔버 장치의 유입구 및 유출구를 상대적으로 면적이 넓게 형성하여 흡입 챔버 내부의 전체 영역에서 균일하고 균등한 공기 흐름이 발생되고, 이러한 공기 흐름을 통해 흡입 챔버 내부로 공급되는 나노 입자가 더욱 원활하게 확산되어 흡입 챔버 내부의 전체 공간에 나노 입자의 농도 분포가 균등하게 형성되며, 이에 따라 실험 동물이 나노 입자에 노출되는 정도가 조건에 따라 정확하게 유지되어 나노 입자 흡입 독성 평가 시험의 신뢰도가 향상되는 노출 챔버 장치를 제공한다.
PCT/KR2010/001503 2009-03-17 2010-03-10 나노 입자 흡입 독성 평가용 노출 챔버 장치 WO2010107204A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090022657A KR101017402B1 (ko) 2009-03-17 2009-03-17 나노 입자 흡입 독성 평가용 노출 챔버 장치
KR10-2009-0022657 2009-03-17

Publications (2)

Publication Number Publication Date
WO2010107204A2 WO2010107204A2 (ko) 2010-09-23
WO2010107204A3 true WO2010107204A3 (ko) 2010-12-09

Family

ID=42740096

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/001503 WO2010107204A2 (ko) 2009-03-17 2010-03-10 나노 입자 흡입 독성 평가용 노출 챔버 장치

Country Status (2)

Country Link
KR (1) KR101017402B1 (ko)
WO (1) WO2010107204A2 (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101221106B1 (ko) * 2010-10-11 2013-01-11 (주)에이치시티 케이지형 흡입 독성 평가 시험 장치
KR101160307B1 (ko) * 2010-12-10 2012-06-28 (주)에이치시티 인비트로 시험이 가능한 나노 입자 노출 장치
KR101312318B1 (ko) * 2012-01-05 2013-09-27 국방과학연구소 자연대류형 에어로졸 시험 장치 및 그 시험방법
KR101332949B1 (ko) * 2012-03-06 2013-11-25 한국화학연구원 나노 입자 흡입 독성 평가 시험용 케이지형 챔버 장치
CN102641156B (zh) * 2012-05-03 2013-10-09 天津开发区合普工贸有限公司 气体染毒舱抗爆安全屏蔽设备
KR101348825B1 (ko) * 2012-07-24 2014-01-08 한국화학연구원 영장류에 대한 나노 입자 흡입 독성 평가 시험용 노출 챔버 장치
KR101463908B1 (ko) * 2013-11-13 2014-11-27 (주)에이치시티 흡입 독성 시험용 다층 케이지형 챔버 장치
KR101642143B1 (ko) * 2014-12-23 2016-07-29 주식회사 에이치시티엠 복수 농도 나노 입자 흡입 독성 시험 챔버 장치
KR101663159B1 (ko) * 2016-02-01 2016-10-07 한국화학연구원 다기능 영장류 실험 장치
KR102112720B1 (ko) 2019-07-01 2020-05-19 주식회사 에이치시티엠 흡입 독성 평가용 전신 노출 챔버 장치
KR102242729B1 (ko) 2019-10-04 2021-04-21 창원대학교 산학협력단 화학사고 피해 진단을 위한 챔버
CN111351922B (zh) * 2020-04-27 2023-09-08 中国烟草总公司郑州烟草研究院 一种体外抽吸烟气多通道暴露染毒方法
CN115041242A (zh) * 2022-04-07 2022-09-13 广州医科大学附属第一医院（广州呼吸中心） 一种新型的污染物气体暴露舱舱体

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100377210B1 (ko) * 2000-12-30 2003-03-26 한국산업안전공단 산업화학물질의 유해성 실험장치
KR20070069317A (ko) * 2005-12-28 2007-07-03 조명행 나노입자 유해성 실험장치
JP2007232453A (ja) * 2006-02-28 2007-09-13 Sumitomo Chemical Co Ltd 吸入毒性試験装置、並びに、吸入毒性試験方法
KR100784763B1 (ko) * 2006-12-01 2007-12-14 재단법인서울대학교산학협력재단 이중노출챔버수단 및 이를 구비한 나노입자 흡입 독성평가용 장치

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100294069B1 (ko) * 1998-11-03 2001-10-26 조순문 용접흄독성실험장치

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100377210B1 (ko) * 2000-12-30 2003-03-26 한국산업안전공단 산업화학물질의 유해성 실험장치
KR20070069317A (ko) * 2005-12-28 2007-07-03 조명행 나노입자 유해성 실험장치
JP2007232453A (ja) * 2006-02-28 2007-09-13 Sumitomo Chemical Co Ltd 吸入毒性試験装置、並びに、吸入毒性試験方法
KR100784763B1 (ko) * 2006-12-01 2007-12-14 재단법인서울대학교산학협력재단 이중노출챔버수단 및 이를 구비한 나노입자 흡입 독성평가용 장치

Also Published As

Publication number Publication date
WO2010107204A2 (ko) 2010-09-23
KR20100104322A (ko) 2010-09-29
KR101017402B1 (ko) 2011-02-28

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