WO2010106551A2 - Procédé pour la fabrication de forme b d'aripiprazole anhydre pure - Google Patents

Procédé pour la fabrication de forme b d'aripiprazole anhydre pure Download PDF

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Publication number
WO2010106551A2
WO2010106551A2 PCT/IN2010/000132 IN2010000132W WO2010106551A2 WO 2010106551 A2 WO2010106551 A2 WO 2010106551A2 IN 2010000132 W IN2010000132 W IN 2010000132W WO 2010106551 A2 WO2010106551 A2 WO 2010106551A2
Authority
WO
WIPO (PCT)
Prior art keywords
aripiprazole
range
process according
temperature
dsc
Prior art date
Application number
PCT/IN2010/000132
Other languages
English (en)
Other versions
WO2010106551A3 (fr
Inventor
Arul Ramkrishnana
Pamujula Srinivasulu
Chittala Venkata Subramanyam
Original Assignee
Neuland Laboratories Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuland Laboratories Ltd. filed Critical Neuland Laboratories Ltd.
Publication of WO2010106551A2 publication Critical patent/WO2010106551A2/fr
Publication of WO2010106551A3 publication Critical patent/WO2010106551A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

La présente invention concerne un nouveau procédé industriellement viable et économique de fabrication de la forme B anhydre sensiblement pure de 7-[4-[4-(2,3-dichlorophényl)-1-pipérazinyl]butoxy]-3,4-di-hydrocarbostyrile également connu sous le nom d'Aripiprazole.
PCT/IN2010/000132 2009-03-09 2010-03-09 Procédé pour la fabrication de forme b d'aripiprazole anhydre pure WO2010106551A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN518/CHE/2009 2009-03-09
IN518CH2009 2009-03-09

Publications (2)

Publication Number Publication Date
WO2010106551A2 true WO2010106551A2 (fr) 2010-09-23
WO2010106551A3 WO2010106551A3 (fr) 2013-02-07

Family

ID=42740074

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2010/000132 WO2010106551A2 (fr) 2009-03-09 2010-03-09 Procédé pour la fabrication de forme b d'aripiprazole anhydre pure

Country Status (1)

Country Link
WO (1) WO2010106551A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014021652A1 (fr) * 2012-08-02 2014-02-06 주식회사 에스텍파마 Cristaux d'aripiprazole anhydres et leur procédé de production
CN104230799A (zh) * 2013-06-21 2014-12-24 江苏豪森药业股份有限公司 制备阿立哌唑晶型的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006528A (en) * 1988-10-31 1991-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
WO2003026659A1 (fr) * 2001-09-25 2003-04-03 Otsuka Pharmaceutical Co., Ltd. Substance pharmaceutique d'aripiprazole faiblement hygroscopique et methodes de preparation associees

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006528A (en) * 1988-10-31 1991-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
WO2003026659A1 (fr) * 2001-09-25 2003-04-03 Otsuka Pharmaceutical Co., Ltd. Substance pharmaceutique d'aripiprazole faiblement hygroscopique et methodes de preparation associees

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014021652A1 (fr) * 2012-08-02 2014-02-06 주식회사 에스텍파마 Cristaux d'aripiprazole anhydres et leur procédé de production
CN104230799A (zh) * 2013-06-21 2014-12-24 江苏豪森药业股份有限公司 制备阿立哌唑晶型的方法

Also Published As

Publication number Publication date
WO2010106551A3 (fr) 2013-02-07

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