WO2010102528A1 - 防治过敏性呼吸道疾病的方法以及实现该方法的口鼻罩 - Google Patents

防治过敏性呼吸道疾病的方法以及实现该方法的口鼻罩 Download PDF

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Publication number
WO2010102528A1
WO2010102528A1 PCT/CN2010/070353 CN2010070353W WO2010102528A1 WO 2010102528 A1 WO2010102528 A1 WO 2010102528A1 CN 2010070353 W CN2010070353 W CN 2010070353W WO 2010102528 A1 WO2010102528 A1 WO 2010102528A1
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Prior art keywords
mouth
main
nose mask
main cover
asthma
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PCT/CN2010/070353
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English (en)
French (fr)
Inventor
李琪
Original Assignee
Li Qi
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Priority claimed from CN2009100475620A external-priority patent/CN101496645B/zh
Priority claimed from CN200920068835U external-priority patent/CN201379090Y/zh
Priority claimed from CNA2009100515859A external-priority patent/CN101584503A/zh
Application filed by Li Qi filed Critical Li Qi
Priority to JP2011549420A priority Critical patent/JP2012517305A/ja
Publication of WO2010102528A1 publication Critical patent/WO2010102528A1/zh
Priority to US13/160,531 priority patent/US8789531B2/en

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    • A—HUMAN NECESSITIES
    • A41—WEARING APPAREL
    • A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D13/00—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
    • A41D13/05—Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches protecting only a particular body part
    • A41D13/11—Protective face masks, e.g. for surgical use, or for use in foul atmospheres
    • A41D13/1107—Protective face masks, e.g. for surgical use, or for use in foul atmospheres characterised by their shape
    • A41D13/1138—Protective face masks, e.g. for surgical use, or for use in foul atmospheres characterised by their shape with a cup configuration
    • A—HUMAN NECESSITIES
    • A41—WEARING APPAREL
    • A41D—OUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D2400/00—Functions or special features of garments
    • A41D2400/10—Heat retention or warming

Definitions

  • the invention relates to a method for preventing and treating allergic respiratory diseases and a mouth and nose mask for realizing the same, belonging to the field of disease control in the medical field, mainly for preventing and treating respiratory diseases such as allergic asthma and allergic rhinitis, and also for preventing and treating common colds. effect. Background technique
  • Allergic respiratory diseases are frequently afflicted, causing different degrees of harm to human health. Especially allergic respiratory diseases such as asthma and allergic rhinitis have always seriously affected the physical and mental health and quality of life of patients. Asthma is considered to be four.
  • One of the major chronic diseases its patients often prolonged unhealed, painful, and even severely died of acute attacks.
  • the current methods for the prevention and treatment of such diseases are mainly medical treatment.
  • the treatment of asthma is mainly to take hormone drugs and theophylline drugs to relax the airway smooth muscle of patients, to achieve the purpose of restoring airway patency.
  • drug treatment such as side effects. Long-term use will lead to drug resistance, which may reduce or even invalidate the drug.
  • the theory recognized by the medical community about asthma is that the pathogenesis of asthma is complicated.
  • the main causes of the disease are allergens, viral infections, air pollution, climate changes (temperature, humidity, pressure changes), drug allergy, exercise, Mental and emotional factors, etc.
  • the main treatments are hormonal drugs to relieve airway obstruction in patients, and long-term medication prevention, through local hot compress and other physical therapy.
  • the current theory does not clearly state what is the most important cause of asthma attacks, nor does it recognize the most direct causal relationship between temperature changes (accurately, temperature declines) and asthma (other predisposing factors). It can be considered secondary, and thus does not really recognize that the insulation of the respiratory tract is the fundamental effective means of treating such diseases.
  • the inventors have verified through long-term experiments that the respiratory tract warming to patients is a fundamental effective treatment for allergic respiratory diseases such as asthma. Paragraph, and propose new theories about such diseases as follows:
  • the cause of asthma is the sudden drop in ambient temperature, which causes the respiratory tract of an allergic body (often highly reactive).
  • the stimulation of stimulating factors such as allergens, bacterial microorganisms, exercise, and mood changes produces abnormal abnormal reactions that produce bronchial mucosal edema. Block the airway and block your breathing.
  • the cause of allergic rhinitis is that the sudden drop in ambient temperature causes an abnormal abnormal reaction in the nasal mucosa of an allergic body, resulting in edema and obstruction of the nasal cavity.
  • the primary and necessary condition for the onset of asthma is the sudden drop in ambient temperature, which is the cause of allergens such as dust mites, microbes, mood changes, etc., which are considered equally important in current medical theory. That is to say, in the environment where there are incentives such as allergens, bacteria, exercise, and mental factors, as long as the ambient temperature does not continue to decrease, people with allergies will not have asthma attacks.
  • the sudden drop in temperature mentioned above means that the temperature has continued to decline for a certain period of time, and the slope of the decline continues to be greater than 0 for a period of time, and the patient is prone to morbidity. If the daily temperature curve is drawn, then the time period during which the ⁇ (temperature) curve is falling is theoretically the time period of the asthma attack. The greater the rate of cooling, the longer the duration of cooling, and the more likely it is to trigger an asthma attack. This is a good explanation for why the onset of asthma is always in the autumn, winter, spring, or early morning, and it also explains why in summer, bacterial microbes, mites, etc. are also dense in the air. Asthma patients are almost no disease.
  • allergic respiratory diseases such as asthma
  • the treatment of allergic respiratory diseases can be simply the only therapeutic target to eliminate the prevalence of sudden drop in ambient temperature.
  • the inventors propose that the method for treating such diseases is to eliminate the factor of environmental temperature drop, or to continuously heat the patient's respiratory tract to prevent the environmental temperature from falling on the patient's respiratory tract and causing the disease.
  • the drop in ambient temperature you can avoid asthma attacks or recover from a state of attack. If you can't change the temperature in your living environment, you can use moist hot air to keep your respiratory tract warm. It must be free from time and space. Cool down, when to use, cool down Long time, long use time, short cooling time, short use time; when to onset, when to use, serious onset, long use time, mild onset, use time can be shorter.
  • the present invention provides a mouth and nose mask, and the invention concept thereof is as follows:
  • the exhaled gas of the human body has a certain heat and is harmless to the human body, so that the human body exhaled gas can be utilized.
  • the heat is heated to heat the next inhaled air, and the cycle is reciprocated to maintain the user's intake air temperature in a range between about 24 ° C and 30 ° C.
  • the nasal mask is a double-layered nasal mask. Its shape and volume are determined according to the face of different patients. The principle is comfortable to wear. There is about 200 ml of gas in the middle of the face and the nose and nose cover.
  • the main vent of the nasal mask enters, and enters the hood from the periphery along the gap between the inner and outer layers.
  • the exhaled gas also discharges the hood from the same path.
  • cold air can be directly impacted on the patient.
  • the inhaled cold air is appropriately heated by the heat of the human exhaled gas.
  • the steam temperature is controlled at about 30 °C, so that the patient continues to inhale warm steam, after about 1 to 2 hours (must be continuously used continuously;), asthma and other symptoms can be alleviated and gradually Restore If it is normal, if the patient is in a more severe acute attack due to a sudden onset, it is difficult to breathe, and the extended use time can be extended until there is recovery. If the ambient temperature suddenly drops again after recovery, it is necessary to continue using hot steam treatment until the ambient temperature is stable.
  • the central portion of the main cover body 1 has a main venting hole 4, the shape and size of which are determined according to the amount of breathing gas of each person, generally circular, and having a diameter of 2 cm to 3 Cm, there may be auxiliary ventilation holes 5 (small round holes with a diameter of about 2 mm) about 3, and the main cover body 1 has a connecting groove 2 for connecting the fixing band 3 for fixing the nasal mask to the head.
  • the inner cover 7 is similar in shape to the main cover 1, and the bottom edge of the inner cover 7 is spaced from the person's face to facilitate air circulation, and a connecting rod 8 is disposed between the inner and outer layers.
  • the main cover body 1 is connected with a face of the human face with a medical rubber gasket 6 for the user to wear comfortably.
  • the air outside the cover is dispersed through the main vent hole to the periphery of the cover, and the gas and heat exhaled by the person are also discharged outside the cover through the edge of the cover, thereby slowing the direct stimulation of the cold air by the cold air.
  • the heat dissipation of the exhaled gas is slowed down, and the temperature of the air sucked by the user is maintained in the range of about 24 ° C to 30 ° C.
  • the main mask body and the inner layer cover of the nose and mouth mask can be made of medical hard engineering plastics, have a certain thickness, and are durable and not easily deformed.
  • the surface of the material in the part of the mouth and nose that is in direct contact with the exhaled gas is selected to be a highly efficient heat storage material, so that the amount of heat exhaled by the person is preserved as much as possible.
  • a heating wire may be added inside the inner cover body, and the power is supplied by an alternating current or a direct current power source.
  • a sodium peroxide sheet-like patch may be applied to the inside of the inner cover, which consists of a raw material layer, a gelatin layer, and a non-woven bag.
  • a mixture of sodium peroxide and a small amount of vermiculite is placed in a non-leakable, air-permeable non-woven bag to form a raw material layer.
  • the back side of the stock layer is a gelatin layer for adhering one side to the inside of the main cover.
  • Sodium peroxide absorbs carbon dioxide exhaled by humans, exothermic and produces oxygen, and the role of vermiculite is to keep warm. This not only prevents the concentration of carbon dioxide from being high, but also helps to increase the temperature of the gas, and also assists oxygen supply.
  • the use of dry sodium hydroxide in tablets also absorbs carbon dioxide and water vapor exhaled by humans.
  • a temperature indicator can be added to display the temperature of the gas in the mouth and nose mask.
  • the invention has the advantages of: avoiding the limitation of the side effect and the curative effect of the medicine on the human body, safe and effective, strong pertinence, no side effect on the human body, reducing or even eliminating the mortality rate of the asthma patient; clarifying the allergic disease such as asthma The most important cause of the disease is to eliminate the fear and helplessness of the disease for a long time.

Description

防治过敏性呼吸道疾病的方法以及实现该方法的口鼻罩 技术领域
本发明涉及一种防治过敏性呼吸道疾病的方法以及实现该方法的口鼻罩， 属 于医疗领域疾病控制范畴， 主要用于预防和治疗过敏性哮喘、 过敏性鼻炎等呼吸 道疾病， 对普通感冒也有防治效果。 背景技术
过敏性呼吸道疾病发病频繁， 对人体健康造成不同程度的危害， 尤其是以哮 喘、 过敏性鼻炎等为主的过敏性呼吸道疾病一直以来严重影响着患者的身心健康 和生活质量， 哮喘被认为是四大顽症之一， 其患者往往迁延不愈、 痛苦不堪， 严 重者甚至会因急性发作而死亡。 目前旨在防治这类疾病的方法主要是药物治疗。 例如治疗哮喘主要是服用激素类药物和茶碱类药物来松弛患者呼吸道平滑肌， 达 到恢复气道通畅的目的。 但是药物治疗存在着一定的局限性比如会产生副作用， 长期使用会产生耐药性使药物疗效降低甚至失效， 患者急性严重发作时药物有时 起效较慢， 患者仍会承受较大的病痛折磨甚至有生命危险。 目前医学界对于哮喘 这类过敏性呼吸道疾病的认识和防治手段一直没有太大变化， 还不能从根本上控 制这类疾病， 哮喘病长期以来一直被列为发病机理不明的世界级的疑难杂症， 每 年全世界仍有数十万严重哮喘患者死于该病。 发明内容
目前医学界公认的关于哮喘病的理论是， 哮喘发病机理复杂， 发病诱因主要 有过敏源剌激、 病毒细菌感染、 空气污染、 气侯变化 （温度、 湿度、 气压变 化） 、 药物过敏、 运动、 精神及情绪因素等等， 治疗手段主要以激素类药物缓解 患者呼吸道阻塞， 并长期用药预防， 通过局部热敷等理疗手段配合。 但是现有理 论没有明确阐明引起哮喘发作的最重要原因是什么， 也未认识到气温的变化 (准确 地说是气温的下降;)和哮喘发病之间有着最直接的因果关系 （其他的诱发因素都可 以认为是次要的） ， 因而也未真正认识到给呼吸道保温才是治疗这类疾病的根本 有效手段。 针对以上现有医学理论和治疗技术的局限， 本发明者通过长期的实 验， 验证了给患者的呼吸道保温是治疗哮喘等过敏性呼吸道疾病的根本有效手 段， 并提出关于这类疾病的新理论如下：
哮喘的发病原因是环境气温的骤降引起过敏体质人体的呼吸道 （往往存在高 反应性） 对过敏源、 细菌微生物、 运动、 情绪变化等剌激因素的剌激产生变态异 常反应从而产生支气管粘膜水肿阻塞气道， 呼吸受阻。 同样， 过敏性鼻炎的发病 原因是环境气温的骤降引起过敏体质人体的鼻腔粘膜产生变态异常反应从而产生 水肿阻塞鼻腔。
众所周知， 当环境气温骤降时， 人体自身免疫能力会有一定的下降， 疾病容 易侵入， 对于非过敏体质的正常人而言， 气温骤降也容易引发感冒， 但不至于引 发哮喘之类的过敏性疾病， 因为正常人不存在气道高反应性， 气候变化时， 对过 敏源等因素的剌激不会产生变态异常反应。
哮喘病发病的首要的也是必要的条件是环境气温骤降， 次要条件才是过敏源 如尘螨、 微生物、 情绪变化等等在当前医学理论中被认为同等重要的诱发哮喘的 原因。 也就是说在存在诸如过敏源、 细菌、 运动、 精神因素等诱因的环境下， 只 要所处环境气温没有出现持续降低的过程， 过敏体质的人就不会出现哮喘发作的 情况。
以上所说的气温骤降， 指气温在一定时间段内有持续的下降， 且下降斜率在 一段时间内持续大于 0， 患者就容易发病。 如果把每天的气温变化曲线画出来， 那 么在 τ (温度） 曲线处于下降过程中的时间段， 理论上都是哮喘病发作的时间段。 降温速率越大， 降温持续时间越长， 越容易引发哮喘发作。 这就能很好地解释为 什么哮喘的发作总是在秋、 冬、 春天的夜间或者凌晨， 也能很好地解释为何在夏 天， 细菌微生物、 螨虫等在空气中的密度也很高的情况下， 哮喘患者几乎不发 病。
因此， 哮喘等过敏性呼吸道疾病的治疗可以简单地以消除环境气温骤降这一 诱因的存在为唯一治疗目标。
基于以上新理论， 本发明者提出治疗这类疾病的方法就是消除环境气温下降 这一因素， 或者对患者的呼吸道进行持续地保温， 避免环境气温下降对患者呼吸 道产生影响而引起发病。 通过消除环境气温下降这一因素可以避免哮喘发作或者 从发作状态恢复健康状态， 在无法改变生活环境气温的情况下， 可以使用湿热空 气对呼吸道进行保温， 必须不受时间和空间的限制， 何时降温， 何时使用， 降温 时间长， 使用时间需要长， 降温时间短， 使用时间可以短些； 何时发病， 何时使 用， 发病程度重， 使用时间长， 发病程度轻， 使用时间可以短些。 通过对呼吸道 进行保温， 避免了过敏体质者的气道产生变态异常反应， 并可以提高呼吸道的抵 抗能力， 增强呼吸道纤毛运动， 便于咳痰， 对于调动和恢复患者自身的免疫能力 杀灭细菌和致敏微生物有较大帮助,最终实现恢复气道的通畅。 这样即使不依赖药 物也能使患者恢复健康。
为了实现以上方法， 达到对人体呼吸道持续保温的目的， 本发明提供了一种 口鼻罩， 它的发明构思是： 人体呼出气体有一定热量且对人体无害， 因此可以利 用人体呼出气体自带的热量来加热下一次吸入的空气， 循环往复， 使使用者的吸 入空气温度保持在约 24°C至 30°C之间的范围内。 该口鼻罩是一个双层口鼻罩， 其 形状和体积根据不同患者的脸型而定， 原则是佩戴舒适， 在人脸和口鼻罩体的中 间大约有 200毫升气体的容量， 空气通过口鼻罩的主通气孔进入， 沿着内、 外层之 间的空隙从四周进入罩内， 呼出气体也从同样路径排出罩体， 戴上本口鼻罩后， 可避免冷空气直接冲击患者的呼吸道， 利用人呼出气体的热量对吸入的冷空气进 行适当地加热。 以下是这种口鼻罩的附图。 附图概述
本发明的具体特征、 性能由以下的实施例及其附图进一步给出。
图 1. 正面示意图
图 2. 侧面示意图
附图标记说明：
1 - 主罩体 2 - 固定带连接槽 3 - 固定带
4 - 主通气孔 5 -辅助通气小孔
6 -橡胶垫圈 7 - 内层罩体 8 -内外层罩体连接杆
9 - 皮肤接触面 (示意） 本发明的最佳实施方式
对呼吸道进行保温， 可以有多种不同的方法， 下面举例说明：
1.使用热蒸汽发生器， 蒸汽温度控制在 30°C左右， 使患者持续吸入温暖的蒸 汽， 经过约 1至 2小时 (必须是不间断地连续使用；)， 哮喘等症状即可缓解并逐步恢 复正常， 若患者若由于突然发作并已经处于较严重的急性发作期， 呼吸较困难， 可延长持续使用时间， 直至有所康复。 在恢复后如再次遇到环境气温突然下降 时， 需要继续使用热蒸汽治疗， 直至环境气温处于稳定的状态下。
2.使用目前市场上用来治疗睡眠呼吸暂停综合症的呼吸机治疗。 将呼吸机输 出气体的温度设定在 30°C左右， 可以不用到呼吸机输出气体提供的正压或负压， 仅需提供持久稳定的暖湿空气， 气压和大气压相近或者略高于大气压， 患者持续 使用时间约 1至 2小时 (必须是不间断地连续使用；)， 哮喘等症状即可缓解并逐步恢 复正常， 若患者由于突然发作并已经处于较严重的急性发作期， 呼吸较困难， 可 延长持续使用时间， 直至有所康复。 若在恢复后再次遇到环境气温突然下降时， 继续重复使用该方法， 直至环境气温处于稳定的状态下。
3.在各类医院建立湿热空气房， 类似医院内有高压氧舱可以用来帮助缺氧病 人恢复健康一样， 湿热空气房中充满温暖湿润的新鲜空气， 温度控制在 30°C左 右， 哮喘患者在发作期可进入其中长时间地静坐或者静卧， 呼吸温暖湿润的新鲜 空气帮助气道恢复抵抗能力杀灭细菌， 增强纤毛运动帮助排痰， 直至恢复气道畅 通。 如果患者处于严重发作期空气房的温度可以设定高一些， 比如 35°C。
4.使用本发明提供的口鼻罩， 说明如下： 主罩体 1的中心区域有主通气孔 4， 其形状和大小根据每个人的呼吸气量而定， 一般为圆形， 直径 2厘米至 3厘米， 另 可有辅助通气小孔 5 (直径 2毫米左右小圆孔） 3个左右， 主罩体 1外部有连接槽 2， 用来连接把口鼻罩固定在头部的固定带 3。 内层罩体 7与主罩体 1形状相似， 内层罩 体 7的底部边缘和人的脸部有一定距离， 便于空气流通， 内外层间有连接杆 8。 主 罩体 1与人脸的接触部位接有一圈医用橡胶垫圈 6， 让使用者佩戴舒适。
使用本口鼻罩时， 罩外空气经过主通气孔分散至罩内的边缘四周进入， 人呼 出的气体和热量也经罩内的边缘四周排出罩外， 减缓了冷空气对呼吸道的直接剌 激， 同时减缓了呼出气体的热量散发， 使用者吸入的空气温度保持在约 24°C至 30 °C的范围内。
口鼻罩主罩体及内层罩体可采用医用硬质工程塑料， 有一定厚度， 经久耐 用不易变形。 口鼻罩内与呼出气体直接接触的部分的材料表面选择高效储热材 料， 使人呼出的热量尽可能保存。 为了增强保温效果， 也可在内层罩体内侧加装 电热丝， 由交流或直流电源供电。 对于对二氧化碳浓度偏高容易产生不适的使用者， 可以另行在内层罩体内侧 加贴过氧化钠片状贴剂， 它由原料层、 明胶层、 无纺布袋三部分组成， 将约 50克 过氧化钠混合少量絰石等混合物置于均匀不漏、 透气性好的无纺布袋内， 形成原 料层。 原料层的背面是明胶层， 用于使其一侧粘附在主罩体的内侧。 过氧化钠吸 收人呼出的二氧化碳， 放热并能产生氧气， 絰石的作用是保温。 这样既能防止二 氧化碳浓度偏高， 又能辅助提高气体温度， 还能辅助供氧。 片剂中使用干燥的氢 氧化钠也可吸收人呼出的二氧化碳和水蒸气。
另外可加装温度指示计显示口鼻罩内气体的温度。
本发明的优点是： 避免了药物对人体的副作用和疗效的局限性， 安全有效， 针对性强， 对人体无副作用， 可降低甚至消除哮喘病人的死亡率； 明确了哮喘这 类过敏性疾病的最重要诱发原因， 消除长期以来人们对该类疾病的恐惧和无奈。

Claims

权利要求
1.一种防治过敏性呼吸道疾病的方法， 其特征在于： 消除环境气温下降这一 因素， 对患者的呼吸道进行持续地保温。
2.根据权利要求 1所述的方法， 其特征在于： 是利用人体呼出气体自带的热 量来加热下一次吸入的空气， 循环往复。
3.—种实现权利要求 1所述方法的口鼻罩， 其特征在于： 其包括主罩体 （1) 和内层罩体 （7) ， 主罩体 （1) 和内层罩体 （7) 之间有一定距离， 主罩体 （1) 中央有主通气孔 （4) ， 内层罩体 （7) 的底部边缘离人脸部有一定距离， 便于空 气出入流通。
4.根据权利要求 3所述的口鼻罩， 其特征在于在主罩体 （1) 的底部边缘有医 用橡胶垫圈 （6) 。
5.根据权利要求 3所述的口鼻罩， 其特征在于主罩体 （1) 上有辅助通气小孔 (5) 。
6.根据权利要求 3所述的口鼻罩， 其特征在于主罩体 （1) 上有固定带 (3) 。
PCT/CN2010/070353 2009-03-13 2010-01-26 防治过敏性呼吸道疾病的方法以及实现该方法的口鼻罩 WO2010102528A1 (zh)

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US13/160,531 US8789531B2 (en) 2009-03-13 2011-06-15 Mouth and nose mask for preventing and treating allergic respiratory diseases

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CN2009100475620A CN101496645B (zh) 2009-03-13 2009-03-13 一种保健口鼻罩
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CN200920068835U CN201379090Y (zh) 2009-03-13 2009-03-13 一种保健口鼻罩
CN200910047562.0 2009-03-13
CNA2009100515859A CN101584503A (zh) 2009-05-20 2009-05-20 一种防治过敏性呼吸道疾病的方法以及实现该方法的口鼻罩
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