WO2010076361A8 - Cuerpos de inclusión, células bacterianas y composiciones que los contienen y sus usos - Google Patents

Cuerpos de inclusión, células bacterianas y composiciones que los contienen y sus usos Download PDF

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Publication number
WO2010076361A8
WO2010076361A8 PCT/ES2009/070616 ES2009070616W WO2010076361A8 WO 2010076361 A8 WO2010076361 A8 WO 2010076361A8 ES 2009070616 W ES2009070616 W ES 2009070616W WO 2010076361 A8 WO2010076361 A8 WO 2010076361A8
Authority
WO
WIPO (PCT)
Prior art keywords
inclusion body
present
refers
compositions containing
bacterial cells
Prior art date
Application number
PCT/ES2009/070616
Other languages
English (en)
French (fr)
Other versions
WO2010076361A1 (es
Inventor
Jaume Veciana Miro
Inmaculada Ratera Bastardas
César DÍEZ GIL
Antonio Pedro Villaverde Corrales
Esther Vázquez Gómez
Elena García Fruitós
Original Assignee
Consejo Superior De Investigaciones Científicas
Universitat Autònoma De Barcelona
Centro De Investigación Biomédica En Red En Bioingenieria, Biomateriales Y Nanomedicina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior De Investigaciones Científicas, Universitat Autònoma De Barcelona, Centro De Investigación Biomédica En Red En Bioingenieria, Biomateriales Y Nanomedicina filed Critical Consejo Superior De Investigaciones Científicas
Priority to EP09836114A priority Critical patent/EP2377946A4/en
Priority to US13/142,295 priority patent/US20110268773A1/en
Priority to JP2011544063A priority patent/JP2012514025A/ja
Priority to CA2749067A priority patent/CA2749067A1/en
Publication of WO2010076361A1 publication Critical patent/WO2010076361A1/es
Publication of WO2010076361A8 publication Critical patent/WO2010076361A8/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La presente invención se refiere a un cuerpo de inclusión aislado que comprende un polipéptido caracterizado porque el cuerpo de inclusión está en forma particulada. La presente invención también se refiere a una célula bacteriana que comprende dicho cuerpo de inclusión. La presente invención se refiere además a una composición que comprende dicho cuerpo de inclusión y una célula eucariota. La presente invención se refiere también a una composición que comprende dicho cuerpo de inclusión y un tejido de animal o planta. La presente invención se refiere también a los usos de dicho cuerpo de inclusión como medicamentos y estimuladores de la proliferación celular y regeneradores de tejido.
PCT/ES2009/070616 2008-12-30 2009-12-22 Cuerpos de inclusión, células bacterianas y composiciones que los contienen y sus usos WO2010076361A1 (es)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP09836114A EP2377946A4 (en) 2008-12-30 2009-12-22 INCLUSION BODY, BACTERIAL CELLS AND COMPOSITIONS CONTAINING SAME, AND USES THEREOF
US13/142,295 US20110268773A1 (en) 2008-12-30 2009-12-22 Inclusion bodies, bacterial cells and compositions containing them and uses thereof
JP2011544063A JP2012514025A (ja) 2008-12-30 2009-12-22 封入体、これを含有する細菌細胞および組成物、ならびにこれらの使用
CA2749067A CA2749067A1 (en) 2008-12-30 2009-12-22 Inclusion bodies, bacterial cells and compositions containing them and their uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ESP200900045 2008-12-30
ES200900045A ES2352489B1 (es) 2008-12-30 2008-12-30 Cuerpos de inclusión, celulas bacterianas y composiciones que los contienen y sus usos.

Publications (2)

Publication Number Publication Date
WO2010076361A1 WO2010076361A1 (es) 2010-07-08
WO2010076361A8 true WO2010076361A8 (es) 2011-10-20

Family

ID=42309867

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2009/070616 WO2010076361A1 (es) 2008-12-30 2009-12-22 Cuerpos de inclusión, células bacterianas y composiciones que los contienen y sus usos

Country Status (6)

Country Link
US (1) US20110268773A1 (es)
EP (1) EP2377946A4 (es)
JP (1) JP2012514025A (es)
CA (1) CA2749067A1 (es)
ES (1) ES2352489B1 (es)
WO (1) WO2010076361A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2857307A1 (en) 2011-12-01 2013-06-06 Barofold, Inc. Methods and systems for protein refolding
CA2928526A1 (en) 2013-11-01 2015-05-07 Spherium Biomed S.L. Inclusion bodies for transdermal delivery of therapeutic and cosmetic agents

Also Published As

Publication number Publication date
WO2010076361A1 (es) 2010-07-08
ES2352489B1 (es) 2012-01-04
ES2352489A1 (es) 2011-02-21
US20110268773A1 (en) 2011-11-03
EP2377946A4 (en) 2013-02-06
EP2377946A1 (en) 2011-10-19
JP2012514025A (ja) 2012-06-21
CA2749067A1 (en) 2010-07-08

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