WO2010064416A1 - 依存性薬物渇望抑制器具およびその使用方法ならびに依存性薬物の依存症治療方法 - Google Patents

依存性薬物渇望抑制器具およびその使用方法ならびに依存性薬物の依存症治療方法 Download PDF

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Publication number
WO2010064416A1
WO2010064416A1 PCT/JP2009/006523 JP2009006523W WO2010064416A1 WO 2010064416 A1 WO2010064416 A1 WO 2010064416A1 JP 2009006523 W JP2009006523 W JP 2009006523W WO 2010064416 A1 WO2010064416 A1 WO 2010064416A1
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Prior art keywords
drug
pseudo
container
addictive
addictive drug
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Ceased
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PCT/JP2009/006523
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English (en)
French (fr)
Japanese (ja)
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平井愼二
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Individual
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Individual
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Priority to AU2009323577A priority Critical patent/AU2009323577A1/en
Priority to EP09830186.4A priority patent/EP2371340A4/en
Priority to US13/132,198 priority patent/US20110257628A1/en
Publication of WO2010064416A1 publication Critical patent/WO2010064416A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06Ampoules or carpules
    • A61J1/062Carpules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035Blister-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00General identification or selection means
    • A61J2205/20Colour codes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00General identification or selection means
    • A61J2205/30Printed labels

Definitions

  • the present invention relates to an addictive drug craving suppression device, a method for using the device, and a method for treating addiction of an addictive drug.
  • conditional reflection occurs in the first signal system only by looking at any one of the seller's face, a stimulant-containing pack, a syringe, and the like, and the operation controlled by the conditional reflection starts.
  • an object of the present invention is to safely and adversely affect treatment even if it is actually administered in a predetermined manner to a dependent person of an addictive drug. Therefore, an object of the present invention is to provide a addictive drug craving-suppressing device that can complete a series of actions by those actions and can obtain an excellent effect on the craving-suppressing treatment of an addictive drug.
  • the present invention comprises a pseudo-addictive drug that has an appearance similar to the form of the dependent drug normally used by dependents of the dependent drug and does not contain an active ingredient of the dependent drug.
  • Addictive drug craving suppression device
  • the present invention is also characterized in that the addictive drug is an antipsychotic drug, anxiolytic drug, antidepressant drug, central nervous stimulant, sleep inducer, sedative hypnotic drug, antihistamine drug, general cold drug, antitussive drug, anesthesia
  • the dependent drug craving suppression device according to (1) which is a drug, an analgesic, a hallucinogen, a stimulant, a cigarette, a smoking cessation aid, a hormone, an alcoholic beverage, an organic solvent or an organic fuel.
  • the pseudo-dependent drug comprises physiological saline, glucose solution, distilled water, glucose, sucrose, lactose, starch, dextrin or sucrose, according to (1) or (2) A device for inhibiting addictive drug craving as described.
  • the present invention also provides the dependent drug according to any one of (1) to (3), wherein the pseudo-dependent drug comprises a pseudo-preparation having an appearance similar to the preparation of the dependent drug.
  • a craving control device e.g., a button, a button, or a button.
  • the pseudo-formulation may be an aerosol, an oral solution, an extract, an elixir, a capsule, a granule, a pill, an eye ointment, a suspension, an emulsion, a transdermal preparation, Suppositories, powders, spirits, tablets, syrups, soaking agents, decoction, injections, patches, tinctures, eye drops, troches, ointments, poultices, fragrances, liniments, limonades, flow Dependent drug craving suppression device according to (4), which is an extract, lotion, spray, pasta, gargle, vaginal, coating, cleaning, enema, bath, tea or electuary It is.
  • the dependency described in (4) or (5) is characterized in that the present invention is also characterized in that an indication indicating that the pseudo-dependent drug is a fake is attached to the surface of the pseudo-formulation. It is a drug craving suppression device.
  • the present invention also provides the pseudo-addictive drug according to any one of (1) to (6), wherein the pseudo-dependent drug is enclosed in a pseudo container having an appearance and structure similar to the container of the dependent drug.
  • the present invention is also the dependent drug craving suppression device according to (7), wherein the fake container is an ampoule, a vial, a bottle, a bag, a syringe, a sheet, a stick, a tube, a container, a bag, or a medicine wrapping paper. is there.
  • the fake container is made of glass, hard plastic, soft plastic, metal, paper, or a combination thereof, and the dependence drug craving suppression according to (7) or (8) It is an instrument.
  • the invention is any one of (7) to (9), characterized in that an indication indicating that the pseudo-dependent drug is a fake is attached to the outer surface of the fake container.
  • the present invention is also characterized in that any one of (7) to (10) is characterized in that a fake packaging having an appearance and structure similar to the packaging applied to the container is applied to the fake container.
  • the addictive drug craving suppression device according to Item is also characterized in that a fake packaging having an appearance and structure similar to the packaging applied to the container is applied to the fake container.
  • the present invention is the addictive drug craving suppression device according to claim 11, wherein the fake packaging is a paper, plastic bag, box, or sheet.
  • the present invention comprises a pseudo-addictive drug that has an appearance similar to the form of the dependent drug normally used by an addict of the dependent drug and does not contain an active ingredient of the dependent drug.
  • a method for using an addictive drug craving suppression device comprising a first procedure of taking the pseudo-addictive drug in a predetermined manner.
  • the present invention may further include a second procedure for opening the pseudo container when the pseudo drug is sealed in a pseudo container having an appearance and structure similar to the container of the drug.
  • the present invention further includes a third procedure for releasing the fake packaging when the fake packaging is provided with a fake packaging having an appearance and structure similar to the packaging of the container.
  • the first procedure includes the step of inserting the injection needle of a syringe into the pseudo container opened by the second procedure when the pseudo-dependent drug is an injection.
  • the pseudo-addictive drug is injected by puncturing the body of the syringe of the syringe that has sucked up the pseudo-dependent drug by the fourth procedure.
  • the present invention also provides the method according to any one of (14) to (18), wherein part or all of the first to fifth procedures are repeatedly performed for a certain period of time or constantly.
  • the present invention comprises a pseudo-addictive drug that has an appearance similar to the form of the dependent drug normally used by dependents of the dependent drug and does not contain an active ingredient of the dependent drug.
  • a method for treating addiction of an addiction drug using an addiction drug craving suppression device comprising the first step of allowing the adder to ingest the pseudodependence drug by a predetermined method. It is a method for treating addiction.
  • the present invention also allows the dependent person to open the pseudo container when the pseudo dependent drug is enclosed in a pseudo container having an appearance and structure similar to the container of the dependent drug.
  • the present invention may further include a third procedure for allowing the relying party to release the fake packaging when the fake container is provided with a fake packaging having an appearance and structure similar to the packaging of the container.
  • (21) A method for treating addiction of an addictive drug according to (21).
  • the first procedure inserts a syringe needle into a pseudo-container opened by the second procedure to the relying party.
  • the method for treating addiction of an addictive drug according to (21) or (22), comprising a fourth procedure in which the pseudo-addictive drug in the pseudo container is sucked up by the syringe.
  • the dependent person in the first procedure, is caused to puncture his / her own body with the injection needle of the syringe that has sucked up the pseudo-dependent drug by the fourth procedure.
  • the present invention is also characterized in that a part or all of the first to fifth procedures are repeatedly performed by the relying party for a certain period or regularly. It is a method for treating addiction of an addictive drug according to any one of the items.
  • the addictive drug craving suppression device of the present invention uses a fake container having an appearance and structure similar to that of the addictive drug container, the dependent drug addict suppressor of the present invention is used.
  • the dependent drug addict suppressor of the present invention is used.
  • the dependence drug craving suppression device of the present invention since a pseudo preparation having an appearance similar to that of the dependence drug preparation is enclosed in the pseudo container, for example, a dependent drug dependent person of the present invention
  • the injection of the real addictive drug was sucked up by the syringe by inserting the injection needle into the opened pseudo syringe of the injection of the dependence drug craving suppression device and sucking up the pseudo injection in the pseudo injection container with the syringe If you open the fake container of the tablet and take it out and put it in your mouth, dissolve the pseudo preparation of the granule in a predetermined solvent, or suck the solution using a predetermined device, Or open the suppository pseudo container, take out the suppository pseudo preparation and insert it into the anus, vagina, etc. Effects can be obtained.
  • the addictive drug craving suppression device of the present invention is encapsulated with a pseudo preparation that does not contain the active ingredient of the above formulation, so that it is safe even if the addictive drug craving suppression device of the present invention is ingested. It is possible to complete a series of actions by activating the first signal condition reflex chain by actually administering it to a dependent drug dependent person in a predetermined manner without adversely affecting the treatment. An excellent effect can be obtained for a drug craving suppression treatment.
  • the addictive drug craving suppression device of the present invention is encapsulated with a pseudo-formulation that does not contain the active ingredient of the above-mentioned preparation, it can be manufactured at a lower cost than a real addictive drug. It is possible to treat addictive drug craving suppression at a lower cost than when drugs are used.
  • the dependent drug craving suppression device of the present invention is provided with a false packaging having an appearance and structure similar to the packaging applied to the container.
  • the dependency drug craving suppression device of the present invention has an indication that the preparation is a fake, and is attached to the surface of the dependency drug or the outer surface of the fake container or fake packaging. Even if a drug addict is a medical worker, a medical accident or the like can be prevented without making a mistake between the addictive drug craving suppression device of the present invention and a genuine addictive drug.
  • FIG. 2 is a schematic front view showing an external configuration of a fake container 21.
  • FIG. 3 is a schematic front view showing a configuration of a pseudo-injection label 41.
  • FIG. 3 is a schematic perspective view showing a configuration of a fake packaging 51.
  • FIG. It is a figure which shows the external appearance structure of the dependence drug craving suppression instrument 12 concerning the 2nd Embodiment of this invention, (A) is the schematic front view, (B) is the schematic rear view. 3 is a schematic front view showing an external configuration of a fake tablet 32.
  • FIG. It is a schematic front view which shows the other example of a fake container.
  • It is a schematic front view which shows the other example of a fake injection label.
  • It is a schematic front view which shows another example of an injection label.
  • FIG. 1 is a schematic cross-sectional view showing the overall configuration of the dependence drug craving suppression device 11 according to the first embodiment of the present invention. As shown in FIG. 1, the dependence drug craving suppression device 11 according to the present embodiment is configured such that a pseudo injection 31 is enclosed in a pseudo container 21.
  • the fake container 21 is an ampoule-type container having an appearance and structure similar to that of a dependent drug (dependent drug X) container. That is, the fake container 21 has a shape, color, pattern, size, weight, and the like similar to the injection container (ampoule type) of the addictive drug X, and has a similar structure. As a result, a dependent drug dependent person sees the fake container 21 of the dependent drug craving suppression device 11, picks it up, or opens the container to view the real dependent drug X injection container. It is possible to obtain a condition stimulus that is almost the same as the condition stimulus obtained when it is picked up by hand or opened.
  • the material of the fake container 21 is not particularly limited, and for example, glass, hard plastic, soft plastic, or the like can be used. For the same reason, a material similar to the injection container for the dependent drug X is used. It is preferable.
  • FIG. 2 is a schematic front view showing the external configuration of the fake container 21.
  • a fake injection label 41 is affixed to the outer surface of the fake container 21.
  • this pseudo-injection label 41 has an appearance similar to a product label attached to an injection container of an addictive drug X, and the product name “XX” of the addictive drug X
  • the product label is almost the same as that of the product label affixed to the injection container for the addictive drug X, except that “false” is added in front of the label.
  • This letter “false” indicates that the pseudo injection 31 enclosed in the pseudo container 21 of the addictive drug craving suppression device 11 is not a real injection of the dependency drug X but a fake injection. Is.
  • Addictive drug craving suppression device 11 may be mistakenly used for self-use of genuine addictive drug X, or conversely, when a dependent person performs a medical act, it may be mistaken for real addictive drug X Medical accidents such as using the sex drug craving suppression device 11 for a patient can be prevented.
  • the dependent drug dependent person knows that the dependent drug craving suppression device 11 is originally a fake and uses it for the craving suppression treatment of the dependent drug, so the fake container 21 is a fake. Even if there is an indication to show that, the therapeutic effect is not affected.
  • the pseudo-injection 31 is liquid and has an appearance similar to that of the injection of the dependent drug X including color and viscosity.
  • the dependent drug dependent person inserts the injection needle into the opened fake container 21 of the dependent drug craving suppression device 11 and sucks up the pseudo injection 31 with the syringe, thereby injecting the genuine dependent drug X.
  • Conditional stimulation that is almost the same as that obtained when the agent is sucked up with a syringe can be obtained.
  • the pseudo-injection 31 does not contain the active ingredient of the injection of the addictive drug X, and is composed of physiologically acceptable ingredients that are harmless to the human body. As a result, even if the pseudo-injection 31 is ingested, it is safe and does not adversely affect the treatment. Therefore, it becomes possible to actually inject the pseudo-injection 31 to the dependent drug addict, and the first signal system condition Since a series of actions by the activation of the reflex chain can be completed, it is possible to obtain an excellent effect on the craving suppression treatment of an addictive drug.
  • Examples of such a pseudo-injection 31 include those composed of the same components as those other than the active ingredient of the dependent drug X, an alternative solution of the active ingredient of the dependent drug X such as physiological saline and glucose solution, and distilled water. The thing etc. which mixed the additive etc. are mentioned.
  • the pseudo container 21 may be subjected to false packaging having an appearance and structure similar to the packaging.
  • the addict who depends on the addictive drug releases the false packaging applied to the fake container 21, thereby stimulating the same condition stimulus as when the packaging applied to the injection container of the genuine addictive drug X is released.
  • false packaging include boxes, bags, binding bands (to bind all or part of the false container 21) made of paper, plastic, etc., and a plurality of false injection containers as shown in FIG. It may be a collective package containing the sachet, or an individual package (not shown) for each fake injection container.
  • the fake packaging may have a display indicating that the fake injection 31 included is a fake, as in the case of the fake injection label 41.
  • the dependent drug craving suppression device 11 is given to a dependent drug dependent person who is a patient, and the dependent person himself / herself picks up the dependent drug craving suppression device 11 and uncovers the fake packaging so that the fake container 21 is removed. Remove (Procedure 1).
  • the fake container 21 taken out by the relying party is scratched by glass cutting or the like at the connecting portion between the body part and the head part, and the fake container 21 is opened by breaking the head part and removing it (procedure) 2).
  • the needle of the syringe is inserted into the pseudo container 21 opened by the relying party, and the pseudo injection 31 in the pseudo container 21 is sucked up by the syringe (procedure 3). Then, the hypodermic needle 31 is pierced into the vein of the dependent person's own arm or the like to inject the pseudo-injection 31, and when the injection is completed, the injection needle is removed from the body (procedure 4). Finally, have the relying party clean up all the equipment used in steps 1-4.
  • each action constituting a series of actions for obtaining and taking the addictive drug is controlled by thinking, and a reward is given after the series of actions is completed.
  • a series of actions before the reward is conditioned, and each action constituting the series of actions is controlled by a corresponding circuit of the first signal system conditional reflection.
  • Each circuit forms a chain by a mechanism in which one circuit becomes a stimulus of the next circuit, and if there is a stimulus related to an addictive drug, this conditional reflex chain reacts actively and takes a series of taking the addictive drug. The state of the action is going to progress.
  • the behavior of the first signal system reflex is automatically activated, as well as the acquisition and intake of substances, because the behavior is conditioned in the early stages of treatment.
  • the conditioning is suppressed because there is no reward after each series of actions in the treatment action, that is, the operability of the first signal system conditional reflex chain that establishes the series of actions is gradually suppressed.
  • the craving for addictive drugs due to conditioned reflexes will disappear.
  • steps 1 to 4 are performed at least 300 times intensively every day from 5 to 15 times in an environment such as hospitalization isolated from society because of craving. It is preferable to repeat about 500 times.
  • a series of actions for searching for, obtaining and ingesting a drug is performed by repeating all steps 1 to 4 in order to perform the operation from the start of the operation to the operation immediately before obtaining the reward by the drug.
  • the quality and quantity of stimulation can be achieved by interrupting the action in the middle of steps 1 to 4 or performing only a part of the action. May be adjusted.
  • Procedures 1 to 4 are preferably repeated not only during a certain intensive treatment period, but also regularly afterwards at a predetermined timing in order to prevent craving for dependent drugs and prevent recurrence.
  • FIG. 5 is a diagram showing an external configuration of the dependence drug craving suppression device 12 according to the second embodiment of the present invention, (A) is a schematic front view thereof, and (B) is a schematic rear view thereof. is there.
  • the dependent drug craving suppression device 12 according to this embodiment is configured by fake tablets 32 enclosed in a fake container 22.
  • the fake container 22 is a sheet-type preparation container having an appearance and a structure similar to that of a tablet container of the addictive drug Y.
  • the pseudo tablet 32 is enclosed by stacking the aluminum foil 222 from above the pseudo tablet 32 in the convex part of the plastic sheet 221 provided with a plurality of convex parts. That is, the fake container 22 has a similar shape, color, pattern, size, weight, and the like to the tablet container (sheet type) of the dependent drug Y, and has a similar structure.
  • the addictive drug craving suppression device 12 can obtain a condition stimulus substantially the same as the condition stimulus obtained by the tablet container of the dependency drug Y in the same manner as the dependency drug craving suppression device 11.
  • the material of the fake container 22 is not particularly limited, and for example, soft plastic, metal, paper, etc., or a combination of these can be used. It is preferable to use a material similar to the container.
  • FIG. 6 is a schematic front view showing the external configuration of the pseudo tablet 32. As shown in FIG. 6, on the front and back surfaces of the fake container 22, except that the product name “XXX” printed on the tablet container of the addictive drug Y is prefixed with “false”. The drug substance Y has almost the same configuration as that printed on the tablet container. This letter “false” has the same effect as the addictive drug craving suppression device 11.
  • the pseudo tablet 32 is solid, and has an appearance similar to that of the dependent drug Y tablet, including color and hardness, except that the upper surface of the pseudo tablet 32 is marked with “false”.
  • the addictive drug craving suppression device 12 can obtain a condition stimulus substantially the same as the condition stimulus obtained by the tablet of the dependency drug Y, similarly to the dependency drug craving suppression device 11.
  • the letters “false” may not be stamped on the upper surface of the fake tablet 32.
  • the pseudo tablet 32 does not contain the active ingredient of the addictive drug Y and has the same effect as that of the addictive drug craving suppression device 11, similarly to the addictive drug craving suppression device 11.
  • Such a pseudo tablet 32 is composed of the same components as those other than the active ingredient of the dependent drug Y, or an alternative substance of the active ingredient of the dependent drug Y such as glucose and sucrose, and lactose, starch, dextrin And those consisting of additives such as excipients such as sucrose.
  • the dependence drug craving suppression device 12 When the dependence drug Y tablet container is packaged, the dependence drug craving suppression device 12 may be subjected to false packaging in the same manner as the dependence drug craving suppression device 11. . Thereby, in the same manner as the dependent drug craving suppression device 11, it is possible to obtain a condition stimulus substantially the same as the condition stimulus obtained by the false packaging.
  • the dependence drug craving suppression device 12 is given to a dependent drug dependent person who is a patient, and the dependent person himself / herself takes the dependence drug craving suppression device 12 in his / her hand. Remove (procedure 5).
  • the convex part of the plastic sheet 221 containing the fake tablet 32 of the fake container 22 taken out by the relying party is strongly pressed with a fingertip, the back side aluminum foil 222 is broken, and the fake container 22 is opened (procedure) 6).
  • the dependent person is made to take out the false tablet 32 from the convex part of the false container 22 (procedure 7).
  • the dependent person is made to put the fake tablet 32 in his / her mouth (procedure 8).
  • the relying party clear everything used in steps 5-8.
  • the treatment using the dependence drug craving suppression device 12 is performed in the same manner as the dependence drug craving suppression device 11.
  • Dependent drug X and addictive drug Y to be mimicked by the dependent drug craving suppression device of the present invention include perphenazine phenothiazines such as chlorpromazine, levomepromazine, thioridazine, fluphenazine, propericazine, haloperidol, bromoperidol , Butyrophenone series such as timiperone, spiperone, pimozide, benzamide series such as sulpiride, sultopride, nemonapride, indole series such as oxypertin, typical antipsychotics such as zotepine, mosapramine, clocapramine, risperidone, perospirone, bronanserin, ziprasidone Serotonin dopamine antagonists (SDA) such as olanzapine and quetiapine, dibenzothiazepines such as quetiapine, multi-receptor targeted antipsychotics
  • Long-acting sedatives such as flunitrazepam, nitrazepam, nimetazepam, estazolam, quazepam, amobarbital, chloral hydrate, and other long-acting sedatives such as flurazepam, phenobarbital, and haloxazolam
  • sleep induction drugs such as begetamine A / B, ramelteon, sedative hypnotics such as barbital and benzodiazepine
  • diphenhydramines such as diphenhydramine hydrochloride, diphenhydramine tannate, Diphenylpyrines such as diphenylpyraline theocluate, tripelenamines such as clemastine fumarate, triprolidine hydrochloride, dl-chlorpheniramine maleate, chlorpheniramine maleate, promethazine hydrochloride, alimemazine tartrate, etc., hydroxy hydrochloride Antiallergic pal
  • the dependency drug craving suppression device of the present invention is not limited to the above-described embodiment, and it is needless to say that various modifications can be made without departing from the gist of the present invention.
  • the dependence drug craving suppression device of the present invention has been described with an example of an ampoule-type fake injection container, but the structure of the fake injection container is not limited to this and mimics it.
  • the drug is appropriately selected according to the structure of the injection container for the addictive medicine.
  • the structure of the pseudo injection container in the dependence drug craving suppression device of the present invention in addition to the ampule type, for example, a vial type structure as shown in FIG. 7, a bottle type, a bag type, a syringe type and the like can be mentioned. .
  • a stick type, a tube type, a container type, a bag type, a medicine-wrapping paper type, and the like can be given.
  • the “false” character in the fake injection label does not necessarily have to be attached in front of the product name. For example, it may be attached to any blank portion of the label. Alternatively, as shown in FIG. 8, it may be displayed as a watermark character or the like superimposed on other characters on the label. Further, the “false” characters do not necessarily have to be printed on the fake injection label, and as shown in FIG. 9, for example, the “false” characters are separated from the fake injection label, a label, a seal, a stamp, etc. It may be configured as follows, and this may be displayed on a pseudo injection label or by attaching it to any part of the pseudo injection container other than the pseudo injection label.
  • the indication that the fake injection is a fake is that the user (dependent person) indicates that the genuine dependence drug and the dependency drug craving suppression device of the present invention are displayed.
  • the display is not particularly limited as long as it can be distinguished.
  • “false” characters for example, “false”, “false”, “fake”, “FAKE”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”, “ ⁇ ”,“ * ”,“ * ”,“? ”,“! ”, Etc., or a specific figure, etc. It may be configured to have a different color from the product label of the real addictive drug.
  • the example of the fake injection container when the product label is affixed to the real dependent drug injection container has been described.
  • the product label is affixed to the real dependent drug injection container.
  • the pseudo-injection container according to the present invention is configured similarly.
  • the method of using the dependence drug craving suppression device of the present invention has been described with reference to an example of intravenous injection. However, it may be used by other injection methods such as infusion. . Further, instead of actually injecting the pseudo-injection according to the present invention using a syringe, for example, a false injection act may be performed using a drug craving suppression device described in Patent Document 1.
  • the dosage form of the addictive drug craving suppression device of the present invention has been described with examples of injections and tablets.
  • other dosage forms such as aerosols, liquids for internal use, Extracts, elixirs, capsules, granules, pills, eye ointments, suspensions, emulsions, transdermal preparations, suppositories, powders, spirits, syrups, soaking agents, decoctions, patching agents, Tincture, eye drops, lozenges, ointments, poultices, fragrances, liniments, limonades, fluid extracts, lotions, sprays, pasta agents, gargles, moisturizers, coating agents, cleaning agents, It may be an enema, bath preparation, tea preparation, electuary or the like.
  • the pseudo-dependent drug according to the dependence drug craving suppression device of the present invention does not necessarily have to be formulated, and may mimic a non-formulation-dependent drug.
  • the act of taking out the pseudo-formulation from the opened fake container by a predetermined method, the act of taking out the pseudo-formulation taken out by the predetermined method, etc. are completely different from the case of acquiring and taking a genuine addictive drug.
  • the addictive drug craving suppression device of the present invention is used for dependent drug addicts and repeats the above-mentioned action for a certain period of time or in a constant manner, whereby an antipsychotic drug, anxiolytic drug, antidepressant drug, central nervous system is used.

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PCT/JP2009/006523 2008-12-02 2009-12-02 依存性薬物渇望抑制器具およびその使用方法ならびに依存性薬物の依存症治療方法 Ceased WO2010064416A1 (ja)

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JP2014140503A (ja) * 2013-01-24 2014-08-07 Shinji Hirai 生理的報酬獲得行動抑制画像集
US9271896B2 (en) * 2014-06-21 2016-03-01 David Clements Apparatus for weight based single doses of medication
JP2016201098A (ja) * 2016-01-04 2016-12-01 愼二 平井 生理的報酬獲得行動抑制画像処理装置、処理方法、処理プログラム及びこれを記憶したコンピュータ読み取り可能な記録媒体並びに生理的報酬獲得行動抑制画像データを記録した記録媒体

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JP5540208B2 (ja) 2014-07-02
JP2010155046A (ja) 2010-07-15

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