WO2010058344A1 - Aiguille dotée de fibres optiques - Google Patents

Aiguille dotée de fibres optiques Download PDF

Info

Publication number
WO2010058344A1
WO2010058344A1 PCT/IB2009/055128 IB2009055128W WO2010058344A1 WO 2010058344 A1 WO2010058344 A1 WO 2010058344A1 IB 2009055128 W IB2009055128 W IB 2009055128W WO 2010058344 A1 WO2010058344 A1 WO 2010058344A1
Authority
WO
WIPO (PCT)
Prior art keywords
needle
fiber
bevel
fibers
tissue
Prior art date
Application number
PCT/IB2009/055128
Other languages
English (en)
Inventor
Bernardus H. W. Hendriks
Augustinus L. Braun
Rik Harbers
Marjolein Van Der Voort
Adrien E. Desjardins
Rami Nachabe
Original Assignee
Koninklijke Philips Electronics N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics N.V. filed Critical Koninklijke Philips Electronics N.V.
Priority to EP09760611.5A priority Critical patent/EP2358263B1/fr
Priority to CN200980146135.6A priority patent/CN102215741B/zh
Priority to US13/129,171 priority patent/US20110251494A1/en
Priority to JP2011543876A priority patent/JP5739817B2/ja
Publication of WO2010058344A1 publication Critical patent/WO2010058344A1/fr
Priority to US15/262,601 priority patent/US11039750B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3401—Puncturing needles for the peridural or subarachnoid space or the plexus, e.g. for anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6848—Needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00057—Light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter

Definitions

  • the invention generally relates to a needle with optical fibers. Particularly, the invention relates to a small diameter needle for tissue inspection based on optical spectroscopy to diagnose whether tissue is cancerous or not.
  • Needle interventions are widely used in the field of oncology for taking biopsies of tissue in order to inspect whether tissue is cancerous or not. To make these interventions more reliable feedback of what kind of tissue is in front of the needle is required. A way to achieve this is by making use of optical spectroscopy. This requires integration of fibers into the needle. These fibers are used to deliver light to illuminate the tissue in front of the needle and to collect back the reflected light from the tissue.
  • a needle according to the invention comprises a shaft, a tip at a distal end of the shaft, wherein the tip of the needle is formed by a bevel, a first fiber, the first fiber being capable of transmitting light, wherein an end surface of the first fiber is located at a top of the bevel, and a second fiber, the second fiber being capable of transmitting light, wherein end surface of the second fiber is located at a bottom of the bevel.
  • the bevel of the needle is in general slanted in order to allow easy entry into the tissue. Therefore, with 'bevel' is meant a geometrical structure allowing for introducing the needle into tissue.
  • a shaft of a needle includes a circular cross section.
  • the distal end of a needle shaft, in particular of a shaft of a hollow needle, is cut such that an oval surface is formed, which is inclined relative to the longitudinal axis of the shaft. Further, there is defined an angle between the longitudinal axis of the shaft and the inclined surface, i.e. the bevel.
  • the bevel forms a pointed tip at the most distal end of the needle. Furthermore, the edge between the outer surface of the shaft and the inclined surface of the bevel might be sharpened.
  • the wording 'top of the bevel' should indicate an area being part of the surface of the bevel, which area is located adjacent to the distal edge between the bevel and the shaft. That is, a fiber which is located at the top of the bevel might be located at the long axis of the oval surface of the bevel, near the distal edge, i.e. the pointed tip.
  • 'bottom of the bevel' means the area being part of the surface of the bevel, which area is located diametric to the top of the bevel. That is, the fiber which is located at the bottom of the bevel might be on or near or adjacent beside the long axis of the oval surface of the bevel near the proximal edge between bevel and shaft.
  • the wording 'bevel' might also enclose similar structures at the tip of the needle, which structures are useful for introducing the needle into a tissue.
  • the bevel might be a convex or concave surface, or the bevel might be a combination of several small surfaces, wherein these surfaces are connected to each other by steps or edges.
  • the cross section of the shaft is not completely cut by the bevel, such that an area remains which is blunt, i.e. is perpendicularly orientated relative to the longitudinal axis of the shaft.
  • Such a 'blunt' end might include rounded edges or might also form a rounded leading edge.
  • a sharp edge might be formed by two or more slanted surfaces being symmetrically or asymmetrically arranged to form the tip of the needle.
  • the bevel forms an acute angle with the shaft, such that the needle includes a pointed tip.
  • the acute angle is approximately 20°.
  • the shaft of the needle has an outer diameter, and the end surface of the first fiber and the end surface of the second fiber are arranged at a distance to each other.
  • the distance between the fiber ends is greater than the diameter of the shaft.
  • the distance is more than 1.1 times greater than the diameter.
  • the distance is more than 1.25 times greater than the diameter.
  • the distance is more than 1.5 times greater than the diameter.
  • the outer diameter of the needle might be 2.108 mm for a brain biopsy needle, between 1.27 mm and 2.108 mm for a common biopsy needle or a neuro puncture needle, between 0.711 mm and 2.108 mm for a fine aspiration needle, between 0.711 mm and 1.473 mm for an epidural needle, and might be 2.108mm or smaller for a needle electrode.
  • the needle further comprises a third fiber which is capable of transmitting light, wherein an end surface of the third fiber is located at the bottom of the bevel in the vicinity of the end surface of the second fiber.
  • the second fiber and the third fiber might be located beside the long axis of the bevel surface.
  • the distance between the fiber at the top of the bevel and one of the fibers at the bottom of the bevel might be 2.46 mm, and the distance between the two fibers at the bottom of the bevel might be 0.37 mm.
  • the distances are measured from the central axis of one of the fibers to the central axis of the other one of the fibers.
  • the shaft of the needle is formed by an inner tube and an outer tube, wherein a space is provided between the inner tube and the outer tube, in which space the fibers are accommodated.
  • the needle with fibers might be use in a system for optical tissue inspection, wherein the system further comprises a light source connected with one of the fibers of the needle, a light detector connected with another one of the fibers of the needle, wherein light coming from the light source and being emitted from the end surface of the one of the fibers can be detected by the light detector when entering the other one of the fibers, a processing unit for processing the data from the light detector, and a monitor for visualization of the processed data.
  • the fiber distal ends in the needle slanted bevel provide at least one source-detector fiber pair with a distance A that is larger than the outer diameter of the needle D, wherein A > LlD or even A >1.25D, and preferably A>1.5D. If b is the tip angle of the needle bevel the following equation might count
  • the needle is provided with a first fiber at the top of the bevel, and with second and third fibers at the bottom of the bevel, the first fiber might be serve as a light source emitting light into surrounding tissue, and the second and third fibers might be two detector fibers collecting reflected light.
  • the invention might also be related to a computer program for the processing unit of the system according to the invention.
  • the computer program is preferably loaded into a working memory of a data processor.
  • the computer program may also be presented over a network like the worldwide web and can be downloaded into the working memory of a data processor from such a network.
  • the computer program might control the emitting of light, might process the signals coming from the light detector at the proximal end of the detector fiber(s). These data might then be visualized at a monitor.
  • Figure 1 shows a cross section of the tip portion of a needle according to a first embodiment of the invention.
  • Figure 2 shows a front view of the needle according to the first embodiment of the invention.
  • Figure 3 shows a front view of a needle according to a second embodiment of the invention.
  • Figure 4 is an isometric illustration of a tip portion of a needle according to the second embodiment of the invention.
  • Figure 5 is a schematic illustration of a system according to the invention, the system including a needle according to a third embodiment of the invention.
  • Figure 1 is a cross sectional view of the tip portion of a needle according to a first embodiment of the invention.
  • the needle 100 includes a shaft 110 having a longitudinal axis or centre axis 150. Parallel to the centre axis, there are formed two bores or channels, in which fibers 130, 140 are located, respectively. These fibers, namely the first fiber 130 and the second fiber 140, include end surfaces 132, 142, respectively.
  • the shaft 110 is cut at its distal end, such that a bevel 120 is formed.
  • the bevel 120 is a slanted surface which can be divided in an area named as top 122 of the bevel, and an area named as bottom 124 of the bevel. Further, the bevel 120 enclose an angle b with the center axis of the shaft 110.
  • the angle b is preferably an acute angle of approximately 20°.
  • the end surface 132 of the first fiber 130 is located at the top of the bevel and the end surface 142 of the second fiber 140 is located at the bottom of the bevel.
  • the bevel together with the ends of the fibers might be polished.
  • a smooth or even surface might be achieved including two end surfaces of fibers, wherein such polished end surfaces provide for good optical characteristics.
  • a distance A is defined, which is measured from a middle of the end surface 132 of the first fiber 130 to the middle of the end surface 142 of the second fiber 140.
  • Figure 2 is a front view of the needle according to the first embodiment of the invention.
  • Figure 2 shows the bevel 120 together with the end surface 132 of the first fiber and the end surface 142 of the second fiber. Furthermore, the usually circular cross section of the shaft of the needle 100 defines a diameter D.
  • the distance A (see figure 1) is larger than the outer diameter D of the needle, wherein A > LlD or even A >1.25D, and preferably A>1.5D.
  • the first fiber might serve as a light source emitting light into surrounding tissue, and the second fiber might serve as a detector fiber collecting reflected light.
  • Figure 3 is a front view of a needle according to a second embodiment of the invention.
  • the second embodiment is similar to the first embodiment.
  • the second embodiment also includes a shaft, a bevel forming an acute angle with the shaft, a first fiber at the top of the bevel, and a second fiber at the bottom of the bevel.
  • the needle according to the second embodiment comprises a third fiber with an end surface 252.
  • the third fiber is arranged in a channel or through bore which is formed parallel to the centre axis of the shaft and, thus, parallel to the channels of the first and second fibers. Further, the end surface 252 of the third fiber is located in the vicinity of the end surface of the second fiber, at the bottom 224 of the bevel 220.
  • the first fiber might serve as a light source emitting light into surrounding tissue
  • the second and third fibers might serve as detector fibers collecting reflected light
  • Figure 4 shows the tip portion of the needle according to the second embodiment as an isometric view. This view illustrates that the actual shape of the surface of the bevel as well as of the end surfaces of the fibers is substantially oval.
  • FIG. 5 illustrates a system according to the invention.
  • the system includes a needle 300 according to a third embodiment of the invention.
  • the needle 300 is an assembly of a tip part 310, an inner tube 352, an outer tube 350, and a holder part 360.
  • two fibers 330 and 340 are shown in the needle.
  • An important part of the needle is the needle tip, in which two or three bores are manufactured. In each bore a fiber is mounted, by gluing.
  • the tip is fixed to both inner tube and outer tube by welding or gluing, wherein the inner and outer diameters of the inner and the outer tube are adapted to correspond respective structures at the proximal shaft section of the tip part.
  • a space 356 between the tubes might be achieved, into which the through bores in the tip part are open out. Coming out of the bores of the tip part, the fibers 330, 340 are positioned in the hollow space 356 between both tubes.
  • the tip, fibers and both tubes once assembled, are fixed to a needle holder. Inside the holder the inner tube is connected with a connector to which for instance a syringe or other tubing can be fixed. In this way volumes of fluid can be dispensed through the channel 354 of the inner tube and tip part, without interaction with the fibers.
  • the needle holder 360 also contains separate exit 362 for the fibers. After assembling tip, fibers, tubes and holder, the bevel 320 of the needle (i.e. the needle tip) is polished to obtain a proper surface quality for the fibers.
  • the tip part might be made of a metal, an alloy or ceramic material
  • the shaft tubes might be made of a metal material, wherein the metal material should be MRI compatible, for example titanium.
  • the system comprises a light source 332, a light detector 242, a processing unit 370 and a monitor 380.
  • the processing unit 370 is capable of controlling the light source 332 to emit light into the fiber 330 such that light will be emitted through the distal end surface of the fiber 330 at the top of the bevel 320 into surrounding tissue. Depending on what kind of tissue is in front of the bevel, more or less of the emitted light will be reflected in the direction of the bottom of the bevel, to be received be the other fiber 340. Through the fiber 340, the light will is led to the light detector 342, which detector is adapted to transform the light into electrical signals. These electrical signals will be send by, for example, wire to the processing unit.
  • the processing unit will process the data corresponding to the electrical signals, so that the processed data might be visualized on a monitor 380. Based on said visualized data, it might be possible to diagnose whether or not a tissue is cancerous.
  • a biopsy needle might have an outer diameter of 1.27 mm up to 2.108 mm, might be inserted into tissue with 100 mm to 150 mm of its length, and might be used in soft tissue core biopsies in the neck, the head, the breast, the prostate, and the liver.
  • a fine aspiration needle of soft tissue might have an outer diameter between 0.711 mm and 2.108 mm, might be inserted into soft tissue with 100 mm to 150 mm of its length, and might be used for aspiration of soft tissue.
  • a brain biopsy needle might have an outer diameter of 2.108 mm, might be inserted into tissue with 150 mm up to 250 mm of its length, and might be used for diagnostic brain biopsies.
  • a neuro puncture needle might have an outer diameter of 1.27 mm up to 2.108 mm, might be inserted into tissue with 150 mm to 200 mm of its length, wherein such needles allow a non-traumatic approach to lesions in the brain.
  • An epidural needle might have an outer diameter between 0.711 mm and
  • 1.473 mm might be inserted into tissue with a length of up to 150 mm, and might be used for treatments in the spinal cord area such as steroid injections in the epidural space.
  • a needle electrode might have an outer diameter of 2 108 mm and smaller, might be inserted into tissue up to 250 mm of its length, and might be used for radio frequency ablation for instance of tumors.
  • a computer program may be stored/distributed on a suitable medium, such as an optical storage medium or a solid-state medium supplied together with or as part of other hardware, but may also be distributed in other forms, such as via the Internet or other wired or wireless telecommunication systems. Any reference signs in the claims should not be construed as limiting the scope.

Abstract

Les aiguilles sont largement utilisées en oncologie pour pratiquer des biopsies de tissu afin de vérifier si le tissu est cancéreux ou non. Pour rendre ces interventions plus fiables, des informations sur le type de tissu se trouvant devant l'aiguille sont nécessaires. Une façon d'obtenir ces informations consiste à utiliser la spectroscopie optique. Cela nécessite l'intégration de fibres dans l'aiguille. Ces fibres fournissent de la lumière pour éclairer le tissu devant l'aiguille et collectent la lumière réfléchie par le tissu. La présente invention propose d'intégrer les extrémités distales de fibres dans le biseau incliné d’une aiguille de façon à ce qu'au moins une paire de fibres source-détecteur ait une longueur plus grande que le diamètre externe de l'aiguille.
PCT/IB2009/055128 2008-11-19 2009-11-18 Aiguille dotée de fibres optiques WO2010058344A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP09760611.5A EP2358263B1 (fr) 2008-11-19 2009-11-18 Aiguille dotée de fibres optiques
CN200980146135.6A CN102215741B (zh) 2008-11-19 2009-11-18 带光纤的针
US13/129,171 US20110251494A1 (en) 2008-11-19 2009-11-18 Needle with optical fibers
JP2011543876A JP5739817B2 (ja) 2008-11-19 2009-11-18 光ファイバを備えるニードル
US15/262,601 US11039750B2 (en) 2008-11-19 2016-09-12 Needle with optical fibers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08169409.3 2008-11-19
EP08169409 2008-11-19

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US13/129,171 A-371-Of-International US20110251494A1 (en) 2008-11-19 2009-11-18 Needle with optical fibers
US15/262,601 Continuation US11039750B2 (en) 2008-11-19 2016-09-12 Needle with optical fibers

Publications (1)

Publication Number Publication Date
WO2010058344A1 true WO2010058344A1 (fr) 2010-05-27

Family

ID=41480178

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/055128 WO2010058344A1 (fr) 2008-11-19 2009-11-18 Aiguille dotée de fibres optiques

Country Status (5)

Country Link
US (2) US20110251494A1 (fr)
EP (1) EP2358263B1 (fr)
JP (1) JP5739817B2 (fr)
CN (1) CN102215741B (fr)
WO (1) WO2010058344A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140121538A1 (en) * 2011-06-28 2014-05-01 Koninklijke Philips N.V. Needle with an optical fiber integrated in an elongated insert
WO2014114921A1 (fr) * 2013-01-24 2014-07-31 University Court Of The University Of St Andrews Appareil optique destiné à être utilisé avec un dispositif d'imagerie médicale
WO2015010213A1 (fr) * 2013-07-26 2015-01-29 The Royal Institution For The Advancement Of Learning/Mcgill University Dispositif de biopsie et procédé d'obtention d'un tomogramme d'un volume tissulaire l'utilisant
WO2015113113A1 (fr) * 2014-02-03 2015-08-06 The University Of Western Australia Dispositif médical à introduire dans une matière pour obtenir un échantillon de matière, et son procédé
CN109171905A (zh) * 2018-10-11 2019-01-11 青岛浦利医疗技术有限公司 基于红外成像的穿刺引导设备
US11076784B2 (en) 2015-03-19 2021-08-03 The Regents Of The University Of Michigan System for analyzing tissue

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9179985B2 (en) * 2008-03-03 2015-11-10 Koninklijke Philips N.V. Biopsy guidance by electromagnetic tracking and photonic needle
WO2013090658A1 (fr) 2011-12-14 2013-06-20 The Trustees Of The University Of Pennsylvania Surveillance d'oxygénation et de flux par fibre optique à l'aide d'une corrélation diffuse et d'un coefficient de réflexion
JP5861000B2 (ja) 2012-06-26 2016-02-16 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 先端で大きなファイバ間隔を有する生検針
US9867599B2 (en) 2013-02-27 2018-01-16 Koninklijke Philips N.V. Optical guided vacuum assisted biopsy device
EP2981207B1 (fr) 2013-04-03 2020-01-22 Koninklijke Philips N.V. Aiguille photonique ayant un angle de biseau optimal
WO2015121115A1 (fr) * 2014-02-14 2015-08-20 Koninklijke Philips N.V. Dispositif photonique ayant une pointe lisse et une sortie de lumière améliorée
CN106793948B (zh) * 2014-08-28 2020-09-29 皇家飞利浦有限公司 侧视肺部活检装置
US10194981B2 (en) * 2015-07-29 2019-02-05 Medlumics S.L. Radiofrequency ablation catheter with optical tissue evaluation
CN105943091A (zh) * 2016-06-01 2016-09-21 南京法迈特科技发展有限公司 一种经内镜穿刺活检器械
CN106137264A (zh) * 2016-09-14 2016-11-23 深圳市前海康启源科技有限公司 具有双光路影像扫描功能的活检穿刺针控制系统
CN206434352U (zh) * 2016-09-14 2017-08-25 深圳市前海康启源科技有限公司 辅助定位的活检穿刺针控制系统
CN206586974U (zh) * 2016-09-14 2017-10-27 深圳市前海康启源科技有限公司 活检穿刺针扫描控制系统

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5460182A (en) 1992-09-14 1995-10-24 Sextant Medical Corporation Tissue penetrating apparatus and methods
WO2005087092A1 (fr) * 2004-02-24 2005-09-22 Wisconsin Alumni Research Foundation Sonde de mise a feu laterale pour effectuer une spectroscopie optique lors d'une biopsie a l'aiguille
US20050261568A1 (en) 2001-09-04 2005-11-24 Bioluminate, Inc. Multisensor probe for tissue identification
US20080009751A1 (en) * 2006-07-10 2008-01-10 Berndt Malka S Optical spectroscopic injection needle
EP1884211A2 (fr) * 2006-08-02 2008-02-06 Stephen D. Zuckerman Dispositif optique pour le positionnement d'une aiguille dans une articulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4566438A (en) * 1984-10-05 1986-01-28 Liese Grover J Fiber-optic stylet for needle tip localization
US6869430B2 (en) * 2000-03-31 2005-03-22 Rita Medical Systems, Inc. Tissue biopsy and treatment apparatus and method
DE10050648C2 (de) * 2000-10-12 2003-11-06 Fraunhofer Ges Forschung Chirurgisches Instrument
SI1413253T1 (sl) 2002-10-25 2006-02-28 Somatex Medical Technologies Gmbh Drzalo biopta za biopsijo z debelo iglo
WO2004082468A2 (fr) 2003-03-17 2004-09-30 Da Silva, Luiz, B. Systeme de biopsie optique a sonde aiguille a usage unique
CN1784173A (zh) * 2003-03-17 2006-06-07 路易兹·B·达·席尔瓦 具有一次性使用的针状探头的光学活组织检查系统
JP4724883B2 (ja) * 2004-05-24 2011-07-13 独立行政法人産業技術総合研究所 生体内組織の同定装置
US7645286B2 (en) * 2005-05-20 2010-01-12 Neotract, Inc. Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues or anatomical structures

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5460182A (en) 1992-09-14 1995-10-24 Sextant Medical Corporation Tissue penetrating apparatus and methods
US20050261568A1 (en) 2001-09-04 2005-11-24 Bioluminate, Inc. Multisensor probe for tissue identification
WO2005087092A1 (fr) * 2004-02-24 2005-09-22 Wisconsin Alumni Research Foundation Sonde de mise a feu laterale pour effectuer une spectroscopie optique lors d'une biopsie a l'aiguille
US20080009751A1 (en) * 2006-07-10 2008-01-10 Berndt Malka S Optical spectroscopic injection needle
EP1884211A2 (fr) * 2006-08-02 2008-02-06 Stephen D. Zuckerman Dispositif optique pour le positionnement d'une aiguille dans une articulation

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140121538A1 (en) * 2011-06-28 2014-05-01 Koninklijke Philips N.V. Needle with an optical fiber integrated in an elongated insert
WO2014114921A1 (fr) * 2013-01-24 2014-07-31 University Court Of The University Of St Andrews Appareil optique destiné à être utilisé avec un dispositif d'imagerie médicale
US10588513B2 (en) 2013-01-24 2020-03-17 University Court Of The University Of St Andrews Optical apparatus for use with a medical imager
WO2015010213A1 (fr) * 2013-07-26 2015-01-29 The Royal Institution For The Advancement Of Learning/Mcgill University Dispositif de biopsie et procédé d'obtention d'un tomogramme d'un volume tissulaire l'utilisant
WO2015113113A1 (fr) * 2014-02-03 2015-08-06 The University Of Western Australia Dispositif médical à introduire dans une matière pour obtenir un échantillon de matière, et son procédé
US10052086B2 (en) 2014-02-03 2018-08-21 The University Of Western Australia Medical device for insertion into a material to obtain a material sample and a method thereof
US11076784B2 (en) 2015-03-19 2021-08-03 The Regents Of The University Of Michigan System for analyzing tissue
CN109171905A (zh) * 2018-10-11 2019-01-11 青岛浦利医疗技术有限公司 基于红外成像的穿刺引导设备
CN109171905B (zh) * 2018-10-11 2020-06-30 青岛浦利医疗技术有限公司 基于红外成像的穿刺引导设备

Also Published As

Publication number Publication date
EP2358263B1 (fr) 2013-07-10
JP2012509161A (ja) 2012-04-19
US11039750B2 (en) 2021-06-22
JP5739817B2 (ja) 2015-06-24
CN102215741B (zh) 2014-07-23
EP2358263A1 (fr) 2011-08-24
US20160374563A1 (en) 2016-12-29
CN102215741A (zh) 2011-10-12
US20110251494A1 (en) 2011-10-13

Similar Documents

Publication Publication Date Title
US11039750B2 (en) Needle with optical fibers
EP2419005B1 (fr) Aiguille avec des fibres intégrées dans les facettes coupantes du biseau
EP2358265B1 (fr) Aiguille avec fibres intégrées
US5280788A (en) Devices and methods for optical diagnosis of tissue
EP2440118B1 (fr) Algorithme pour console d'aiguille photonique
US20140121538A1 (en) Needle with an optical fiber integrated in an elongated insert
EP2961327B1 (fr) Dispositif de biopsie assistée sous vide à guidage optique
US20060264745A1 (en) Optical biopsy system with single use needle probe
US20040249268A1 (en) Optical biopsy system with single use needle probe
US20140213911A1 (en) Needle device with an optical fiber integrated in a movable insert
EP2744396A1 (fr) Sonde médicale équipée d'une lumière multi-fibres
US10052086B2 (en) Medical device for insertion into a material to obtain a material sample and a method thereof
CA3163914A1 (fr) Appareil endoscope a aiguille ultrafine pour examen interstitiel profond par imagerie a lumiere blanche, imagerie par autofluorescence et spectroscopie raman

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200980146135.6

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09760611

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2009760611

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2011543876

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 13129171

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 4165/CHENP/2011

Country of ref document: IN