WO2010054203A8 - Non-contact frequency domain near infrared absorption (fnir) device for assessing tissue damage - Google Patents

Non-contact frequency domain near infrared absorption (fnir) device for assessing tissue damage Download PDF

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Publication number
WO2010054203A8
WO2010054203A8 PCT/US2009/063564 US2009063564W WO2010054203A8 WO 2010054203 A8 WO2010054203 A8 WO 2010054203A8 US 2009063564 W US2009063564 W US 2009063564W WO 2010054203 A8 WO2010054203 A8 WO 2010054203A8
Authority
WO
WIPO (PCT)
Prior art keywords
wound
source
light
fnir
detectors
Prior art date
Application number
PCT/US2009/063564
Other languages
French (fr)
Other versions
WO2010054203A1 (en
Inventor
Elisabeth S. Papazoglou
Leonid Zubkov
Original Assignee
Drexel University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drexel University filed Critical Drexel University
Priority to EP09825481.6A priority Critical patent/EP2348967A4/en
Priority to US13/125,116 priority patent/US20110208063A1/en
Publication of WO2010054203A1 publication Critical patent/WO2010054203A1/en
Publication of WO2010054203A8 publication Critical patent/WO2010054203A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/445—Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7228—Signal modulation applied to the input signal sent to patient or subject; demodulation to recover the physiological signal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
    • A61B2562/0242—Special features of optical sensors or probes classified in A61B5/00 for varying or adjusting the optical path length in the tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077—Devices for viewing the surface of the body, e.g. camera, magnifying lens

Abstract

A device for measuring the progress of healing of a wound over time includes at least one diode laser source that provides respective input wavelengths into at least one source fiber, a first optical switch that sequentially switches wavelengths among the respective input wavelengths into the at least one source fiber, a probe that does not touch the wound dunng use, the probe including the at least one source fiber and at least two detectors spaced thereon, an optical system that provides source light from the at least one source fiber to the wound and that detects light scattered by the wound surface and provides the scattered light to the detectors, and a processing unit responsive to outputs of the detectors for providing at least four independent measurements for calculation of an absorption coefficient /Ia and a scattering coefficient /I's of the light by the wound
PCT/US2009/063564 2008-11-06 2009-11-06 Non-contact frequency domain near infrared absorption (inir) device for assessing tissue damage WO2010054203A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP09825481.6A EP2348967A4 (en) 2008-11-06 2009-11-06 Non-contact frequency domain near infrared absorption (fnir) device for assessing tissue damage
US13/125,116 US20110208063A1 (en) 2008-11-06 2009-11-06 NON-CONTACT FREQUENCY DOMAIN NEAR INFRARED ABSORPTION (fNIR) DEVICE FOR ASSESSING TISSUE DAMAGE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11192408P 2008-11-06 2008-11-06
US61/111,924 2008-11-06

Publications (2)

Publication Number Publication Date
WO2010054203A1 WO2010054203A1 (en) 2010-05-14
WO2010054203A8 true WO2010054203A8 (en) 2011-04-28

Family

ID=42153256

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/063564 WO2010054203A1 (en) 2008-11-06 2009-11-06 Non-contact frequency domain near infrared absorption (inir) device for assessing tissue damage

Country Status (3)

Country Link
US (1) US20110208063A1 (en)
EP (1) EP2348967A4 (en)
WO (1) WO2010054203A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2861132B1 (en) 2012-06-13 2020-11-18 Dean Nahman Devices for detection of internal bleeding and hematoma
US9645086B2 (en) * 2013-08-30 2017-05-09 Kabushiki Kaisha Toshiba Componential analysis method, componential analysis apparatus and non-transitory computer-readable recording medium
US20160296158A1 (en) * 2013-11-21 2016-10-13 Drexel University Non-invasive multi-frequency oxygenation spectroscopy device using nir diffuse photon density waves for measurement and pressure gauges for prediction of pressure ulcers
FR3032527B1 (en) * 2015-02-06 2020-03-13 Commissariat A L'energie Atomique Et Aux Energies Alternatives DEVICE FOR MEASURING AN OPTICAL SIGNAL BACKPACKED BY A SAMPLE
US10682081B2 (en) * 2015-12-21 2020-06-16 Outerfacing Technology LLC Acquiring and processing non-contact functional near-infrared spectroscopy data

Family Cites Families (20)

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US4286602A (en) * 1979-06-20 1981-09-01 Robert Guy Transillumination diagnostic system
US5792051A (en) * 1988-12-21 1998-08-11 Non-Invasive Technology, Inc. Optical probe for non-invasive monitoring of neural activity
US6246892B1 (en) * 1991-01-24 2001-06-12 Non-Invasive Technology Phase modulation spectroscopy
US5416582A (en) * 1993-02-11 1995-05-16 The United States Of America As Represented By The Department Of Health And Human Services Method and apparatus for localization and spectroscopy of objects using optical frequency modulation of diffusion waves
US6957094B2 (en) * 1994-12-02 2005-10-18 Non-Invasive Technology, Inc. Examination of scattering properties of biological tissue
GB9610700D0 (en) * 1996-05-22 1996-07-31 Moor Instr Ltd Apparatus for imaging microvascular blood flow
US6721582B2 (en) * 1999-04-06 2004-04-13 Argose, Inc. Non-invasive tissue glucose level monitoring
US6353226B1 (en) * 1998-11-23 2002-03-05 Abbott Laboratories Non-invasive sensor capable of determining optical parameters in a sample having multiple layers
US7904139B2 (en) * 1999-08-26 2011-03-08 Non-Invasive Technology Inc. Optical examination of biological tissue using non-contact irradiation and detection
US6795195B1 (en) * 1999-09-14 2004-09-21 Research Foundation Of State University Of New York System and method for tomographic imaging of dynamic properties of a scattering medium
EP1251779A1 (en) * 2000-01-27 2002-10-30 National Research Council of Canada Visible-near infrared spectroscopy in burn injury assessment
NO325061B1 (en) * 2001-03-06 2008-01-28 Photosense As Method and arrangement for determining the optical property of a multilayer tissue
US6943881B2 (en) * 2003-06-04 2005-09-13 Tomophase Corporation Measurements of optical inhomogeneity and other properties in substances using propagation modes of light
US7920908B2 (en) * 2003-10-16 2011-04-05 David Hattery Multispectral imaging for quantitative contrast of functional and structural features of layers inside optically dense media such as tissue
US20050281476A1 (en) * 2004-03-23 2005-12-22 Yoshihisa Tanikawa Examination apparatus
US20060241495A1 (en) * 2005-03-23 2006-10-26 Eastman Kodak Company Wound healing monitoring and treatment
US20090062685A1 (en) * 2006-03-16 2009-03-05 Trustees Of Boston University Electro-optical sensor for peripheral nerves
US7460248B2 (en) * 2006-05-15 2008-12-02 Carestream Health, Inc. Tissue imaging system
BRPI0712705A8 (en) * 2006-06-12 2015-10-06 Koninklijke Philips Electonics N V WOUND MONITORING DEVICE, AND, METHODS OF ACQUISITION OF WOUND DATA AND DETECTION OF THE PRESENCE, LOCATION AND/OR STAGE OF A WOUND
US8070682B2 (en) * 2006-07-19 2011-12-06 The University Of Connecticut Method and apparatus for medical imaging using combined near-infrared optical tomography, fluorescent tomography and ultrasound

Also Published As

Publication number Publication date
EP2348967A4 (en) 2014-07-02
EP2348967A1 (en) 2011-08-03
US20110208063A1 (en) 2011-08-25
WO2010054203A1 (en) 2010-05-14

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