WO2010047082A1 - Substance mixing device, and casing employed in same - Google Patents

Substance mixing device, and casing employed in same Download PDF

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Publication number
WO2010047082A1
WO2010047082A1 PCT/JP2009/005468 JP2009005468W WO2010047082A1 WO 2010047082 A1 WO2010047082 A1 WO 2010047082A1 JP 2009005468 W JP2009005468 W JP 2009005468W WO 2010047082 A1 WO2010047082 A1 WO 2010047082A1
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WO
WIPO (PCT)
Prior art keywords
casing
sealed
opening
mixture
substance
Prior art date
Application number
PCT/JP2009/005468
Other languages
French (fr)
Japanese (ja)
Inventor
大山義夫
Original Assignee
Oyama Yoshio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oyama Yoshio filed Critical Oyama Yoshio
Publication of WO2010047082A1 publication Critical patent/WO2010047082A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2093Containers having several compartments for products to be mixed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/25Mixers with loose mixing elements, e.g. loose balls in a receptacle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/25Mixers with loose mixing elements, e.g. loose balls in a receptacle
    • B01F33/251Mixers with loose mixing elements, e.g. loose balls in a receptacle using balls as loose mixing element
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/713Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/713Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7131Breaking or perforating packages, containers or vials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71Feed mechanisms
    • B01F35/716Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
    • B01F35/7164Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being placed in parallel before contacting the contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205Separate rigid or semi-rigid containers joined to each other at their external surfaces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202Separating means
    • A61J1/2027Separating means having frangible parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2079Filtering means
    • A61J1/2086Filtering means for fluid filtration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096Combination of a vial and a syringe for transferring or mixing their contents

Definitions

  • the present invention relates to a substance mixing apparatus for mixing substances enclosed in an ampule and a casing used for the substance mixing apparatus.
  • a multi-chamber container has been proposed to mix two kinds of liquids.
  • the multi-chamber container has a structure in which the internal space of the resin package is divided into two, for example, and the liquid to be mixed is sealed in each of the two chambers formed by dividing the package into two. . Then, when necessary, the two partitions are separated from each other by damaging the partition that separates the two chambers, or by peeling off the weak seal portion that forms the partition, thereby mixing the two liquids.
  • Patent Document 1 Japanese Patent Laid-Open No. 2008-206686
  • the multi-chamber container as described above is made of resin, the types of liquid that can be sealed are limited. Specifically, it is not possible to enclose liquids that erode the resin and weakly sealed portions in a multi-chamber container for a long period of time.
  • the first object of the present invention is to provide a substance mixing device capable of relaxing restrictions on the types of substances that can be sealed, and a casing used for the substance mixing apparatus.
  • the second object of the present invention is to provide a reusable substance mixing apparatus and a casing used for the substance mixing apparatus.
  • the present invention basically relates to a substance mixing apparatus 10 that obtains a mixture by mixing substances.
  • the substance mixing apparatus 10 of the present invention includes a casing 1 made of a flexible material.
  • the casing 1 has an opening 1a.
  • a plurality of sealed ampules 2 are accommodated in the casing 1.
  • all of the plurality of sealed ampules 2 have breakability.
  • the mixture can be obtained quickly by simply damaging the sealed ampoule 2 in the casing 1. That is, the fluid or substance to be mixed has a long time in the state of being sealed in the sealed ampoule 2. For this reason, there are almost no restrictions on the types of substances that can be sealed in the sealed ampoule 2, and the restrictions on the types can be relaxed as compared with the conventional case. Moreover, it is not necessary for the obtained mixture to contact the casing 1 for a long time. For this reason, even if the casing 1 is made of a material that is easily eroded by the mixture, durability that can withstand at least one use is obtained.
  • the substance mixing apparatus 10 of the present invention it is not necessary to divide the space in the casing 1 into two. That is, it is not necessary to provide a partition wall or a weak seal portion on the casing 1. For this reason, as long as the casing 1 does not deteriorate, it can be reused.
  • the substance mixing apparatus 10 of the present invention includes the recovery container 3, and the filter unit 5 is disposed between the casing 1 and the recovery container 3. This prevents the damaged sealed ampoule 2 from entering the recovery container 3 from the casing 1. Thereby, the possibility that the damaged sealed ampoule 2 is mixed into the target mixture can be eliminated.
  • the closing member 7 is made of an elastic material and can pierce a hollow needle-like object. Using this, while maintaining the airtightness of the space formed by the casing 1 and the recovery container 3, at least a part of the mixture recovered in the recovery container 3 is taken out, or other substances are mixed into the mixture. It becomes possible to do.
  • the mixture collected in the collection container 3 may be stirred using the stirring bar 9.
  • the substance mixing device 10 of the present invention further includes a spray device that can be attached to the collection container 3.
  • This spraying device is attached to the collection container 3 instead of the casing 1.
  • the spray device can spray the mixture collected in the collection container 3. This makes it easier to use the mixture.
  • the casing 1 described above is a member that is long in the longitudinal direction with the opening 1a as one end, and preferably includes a plurality of storage chambers, for example, a first storage chamber and a second storage chamber.
  • the first storage chamber is arranged at one end (opening 1a side) in the longitudinal direction of the casing, and the second storage chamber connected to the first storage chamber is arranged at the other end side in the longitudinal direction.
  • the sealed ampule 2 is accommodated in the first accommodation chamber and the second accommodation chamber. Thereby, the accommodation place of the sealed ampoule 2 can be easily understood. For this reason, the mixing order of substances can be adjusted in the order of selecting the storage chambers.
  • another aspect of the present invention is a casing having a function equivalent to that of the casing 1 used in the substance mixing apparatus 10.
  • a casing suitable for use in the substance mixing apparatus 10 can be provided.
  • the substance mixing apparatus 10 that can relax the restriction on the types of substances that can be sealed. Further, according to the present invention, a reusable substance mixing apparatus 10 can be provided. Furthermore, according to the present invention, a casing 1 suitable for use in the substance mixing apparatus 10 can be provided.
  • FIG. 1 is a front view schematically showing the configuration of the substance mixing apparatus of the present invention.
  • FIG. 2 is a diagram used for explaining an example of another shape of the collection container shown in FIG.
  • FIG. 3 is a diagram used for explaining an example of a state when the substance mixing apparatus of FIG. 1 is used.
  • FIG. 4 is a view showing a substance mixing apparatus according to another embodiment of the present invention.
  • FIG. 1 is a front view schematically showing a configuration of a substance mixing apparatus 10 of the present invention.
  • the substance mixing apparatus 10 of the present invention is for obtaining a fluid mixture by mixing substances sealed in a plurality of sealed ampules 2 (for example, 2a, 2b, 2c described later).
  • a substance mixing apparatus 10 shown in FIG. 1 includes a casing 1.
  • the substance mixing apparatus 10 further includes a collection container 3, a filter unit 5, a closing member 7, and a stirrer 9.
  • the sealed ampoule 2 a damaging one can be used, for example, a glass one.
  • the sealed ampoule 2 is not limited to glass but may be made of a material having brittleness (fragility). Further, in order to enhance the breakability of the sealed ampoule 2, the sealed ampoule 2 is preferably long. Further, in order to enhance the breakability of the sealed ampoule 2, a portion having a partially different thickness may be provided by forming a cut or a groove in the sealed ampoule 2. By doing in this way, even if it is a material (for example, resin material) which is not brittle, it can be used as the constituent material of the sealing ampoule 2.
  • the casing 1 is made of a flexible material, and is made of a resin material such as PP (polypropylene) or PET (polyethylene terephthalate). In this way, the casing 1 can be stretched and deformed by being made of a flexible material. Note that the casing 1 does not need to be entirely made of a flexible material, and at least a portion for accommodating the sealed ampoule 2 only needs to be made of a flexible material. A part of the casing 1 is made of a flexible material, and the remaining part is made of a material having a relatively high rigidity, thereby making it possible to localize an easily deformable place. Bending and twisting are easy.
  • PP polypropylene
  • PET polyethylene terephthalate
  • the casing 1 has a hollow cylindrical bag shape, and the length in the longitudinal direction is, for example, 100 mm. And this casing 1 has the opening part 1a in the end. The opening 1a is used when the sealed ampoule 2 is taken in and out and the mixture is recovered.
  • the casing 1 may have a plurality of storage chambers as will be described later.
  • Examples of the length of the casing 1 are 1 cm or more and 20 cm or less, 2 cm or more and 10 cm or less, or 3 cm or more and 7 cm or less.
  • a portion of the casing 1 that is flexible by the flexible material is a flexible portion that can be bent by the human power.
  • the entire casing 1 is made of a flexible material, it is not necessary for all of the casing 1 to have flexibility. For example, only the side surface of the casing 1 may have flexibility.
  • the collection container 3 is shaped like a bottle whose lower part is wider than the upper part, and a neck part 3 a is provided at the upper part.
  • the material constituting the collection container 3 is, for example, PET (polyethylene terephthalate).
  • PET polyethylene terephthalate
  • the material which comprises the collection container 3 is not restricted to resin materials, such as PET, For example, durable materials, such as glass, may be sufficient.
  • the shape of the collection container 3 is not limited to the bottle shape.
  • the shape of the collection container 3 can be made compact by making the portion excluding the neck portion 3a the same diameter, thereby making it easier to hold.
  • the neck 3a of the collection container 3 has a circular first opening 3b that opens upward.
  • the first opening 3b of the casing 1 can be connected to the neck 3a by extending and covering the vicinity of the opening of the casing 1 with its flexibility. Thereby, the opening 1a of the casing 1 and the first opening 3b of the recovery container 3 are connected to each other. Further, the connecting portion is sealed by the flexibility of the casing 1. That is, the connection portion has a structure in which liquid leakage and liquid or gas entry are unlikely to occur.
  • the filter unit 5 is disposed between the casing 1 and the collection container 3.
  • This filter unit 5 includes at least one filter, and this filter prevents a substance larger than the mesh of the filter from passing through, and passes a substance smaller than the mesh. It is supposed to let you.
  • the filter constituting the filter unit 5 is preferably selected as appropriate according to the fluidity (viscosity) of the target mixture. For example, in the case of a highly viscous mixture, it is preferable to prevent damage to the filter by increasing the thickness of the filter or increasing the rigidity of the filter. Further, a material larger than the mesh may be collected in a relatively low portion by curving the filter and providing a concave portion or a convex portion in the central portion. As a result, clogging of the mesh can be prevented and the portion where the filter is easily damaged can be narrowed.
  • the filter unit 5 includes a filter built-in type perforated rubber stopper 5a and a seal filter 5b as shown in FIG.
  • the perforated rubber stopper 5a is a rubber stopper having a tapered surface, provided with a plurality of through holes along the axial direction of the cylinder, and a filter disposed above the through holes.
  • the stopper need not be made of rubber.
  • the perforated rubber stopper 5a is fitted into the first opening 3b.
  • the seal filter 5b is made of, for example, a fine mesh resin material (for example, TPE (thermoplastic elastomer)). As shown in FIG.
  • a circular second opening 3c is provided on the side surface of the collection container 3 separately from the first opening 3b.
  • the second opening 3c opens upward.
  • the 2nd opening part 3c may be opened toward the side.
  • This 2nd opening part 3c is used when collect
  • the second opening 3c is also used when adjusting the pressure of the space formed by the casing 1 and the recovery container 3 when the casing 1 and the recovery container 3 are connected.
  • an aspirator may be connected to the second opening 3c in order to reduce the pressure in the collection container 3.
  • the closing member 7 is a member for closing the second opening 3c. Thereby, the 2nd opening part 3c is sealed.
  • a rubber plug, a cork plug, a cap (single), a double cap, a stretchable film, or the like can be used as the closing member 7, a rubber plug, a cork plug, a cap (single), a double cap, a stretchable film, or the like.
  • the double cap is a member provided with a partition wall at a substantially central portion on the inner peripheral side of a hollow cylindrical member. One end of the double cap is fitted into the opening, and the other end is deformed so as to be folded back to the one end side, so that the partition wall is exposed to the outside.
  • a cap having a shape complementary to the second opening 3 c is used as the closing member 7.
  • a hollow needle-like object can be inserted into the cap.
  • the hollow needle-like material include a syringe (injector, injector) needle.
  • injector injector
  • the closing member 7 is preferably made of an elastic material.
  • the stirring bar 9 is used by being put in the collection container 3 when stirring the liquid mixture.
  • two spherical bodies are used as the stirring bar 9.
  • the stirrer 9 moves so as to roll on the bottom surface of the recovery container 3 only by moving the recovery container 3.
  • the mixture is also agitated as the stirrer 9 moves.
  • the size of at least one of the first opening 3b and the second opening 3c is determined in consideration of the size of the stirrer 9 and the clearance. Is preferred. More preferably, at least the size of the second opening 3c is determined in consideration of the size of the stirring bar 9 and the clearance.
  • the substance mixing apparatus 10 will be described from a state where it is not assembled as shown in FIG.
  • a sealed ampoule 2 in which a necessary amount of a substance to be mixed is enclosed is prepared for the number of types of substances to be mixed (for example, three).
  • the substances to be mixed is a fluid, and in the example shown in FIG. 1, it is enclosed in a sealed ampoule 2a.
  • the other substance to be mixed is selected from the group consisting of a solid, a liquid that is dispersed or dissolved in the fluid, and a gas that is soluble in the fluid.
  • the sealed ampules 2b and 2c are selected. Is enclosed.
  • the substances to be mixed are most preferably liquids in that a mixture is obtained quickly and does not diffuse toward the outside air.
  • the sealed ampoule 2 can be prepared, for example, by preparing a hollow glass pipe, placing a substance to be sealed in the hollow portion, and closing the open end of the glass pipe with heat or the like. If the material to be sealed is a liquid or a material that is weak against heat, a glass material having one open end may be prepared. When the substance to be sealed is strong against ultraviolet rays, a sealed cell ampule 2 may be prepared by preparing a glass cell and bonding the cell and the cell cap with an ultraviolet curable resin. Further, a commercially available sealed ampoule 2 encapsulating a substance may be prepared.
  • the prepared sealed ampules 2 are put into the casing 1 of the substance mixing apparatus 10 through the openings.
  • the substances to be mixed if there is a substance that does not need to be sealed in the sealed ampoule 2, it may be put directly into the casing 1 or the collection container 3.
  • the collection container 3 provided with the filter part 5 is prepared, and the collection container 3 and the casing 1 are connected.
  • three sealed ampoules 2a, 2b, 2c accommodated in the casing 1 are indicated by hidden lines (broken lines).
  • the stirrer 9 is introduced into the collection container 3, and after the introduction, the second opening 3 c of the collection container 3 is airtightly covered with the closing member 7.
  • the air inside the space formed by the casing 1 and the recovery container 3 may be replaced with a desired gas, or removed using an aspirator or the like. You may care.
  • a desired gas or removed using an aspirator or the like.
  • the gas used for the substitution mention may be made of argon (Ar) and nitrogen (N 2) an inert gas, such as.
  • the gas that is the mixing target may be filled as the gas used for the replacement.
  • the sealed ampoule 2 housed in the casing 1 is broken. Specifically, the sealed ampoule 2 may be grasped by hand indirectly from the outside of the casing 1 and folded.
  • a material having flexibility is used as the material of the casing 1, not only can the sealed ampoule 2 be easily broken, but there is no risk of injury even if it is grasped by hand.
  • the sealed ampoule 2 may be damaged by remote control.
  • remote operation external pressure is applied to the casing 1 so that the casing 1 bends or the casing 1 is twisted, or the pressure inside the casing 1 is lowered, or from the outside.
  • vibration (ultrasonic wave) or the like may be applied to the sealed ampoule 2.
  • the present invention is effective in that the mixture can be obtained in a place where a person such as a clean room cannot enter.
  • substances that are harmful to the human body can be prepared without human attendance.
  • the substance enclosed in the sealed ampoule 2 diffuses into the casing 1 and becomes a mixture.
  • the mixing order may become a problem.
  • the casing 1 is preferably made of a transparent material, whereby the plurality of sealed ampoules 2 can be distinguished from the outside of the casing 1.
  • the casing 1 includes at least a first storage chamber disposed at one end in the longitudinal direction and connected to the opening 1a, and a second storage chamber connected to the first storage chamber.
  • the chamber contains a sealed ampule 2b in which a solid substance is enclosed
  • the second accommodation chamber contains a sealed ampule 2a in which a liquid is enclosed.
  • the sealed ampoule 2b located in the lower part in the vertical direction is first broken, and then the sealed ampoule 2a is broken, so that the solid substance can flow down while being dissolved in the liquid. That is, it becomes difficult for the solid substance to remain in the casing 1.
  • the sealed ampoule 2 at the upper side in the vertical direction may be broken before the sealed ampoule 2 at the lower side.
  • the storage chambers may be provided on the other end side in the longitudinal direction of the casing 1 so as to be connected to the second storage chamber.
  • the mixture moves from the casing 1 through the filter unit 5 to the collection container 3 below.
  • the filter unit 5 prevents the fragments of the sealed ampules 2a, 2b, 2c from entering the collection container 3.
  • only the mixture can be recovered.
  • the casing 1 having flexibility can be crushed and moved to the collection container 3 side.
  • FIG. 3 shows a state when the needle of the syringe is inserted into the closing member 7.
  • a syringe needle can be inserted into the closure member 7 and a portion of the mixture can be removed for analysis, for example. Since an elastic material is used as the closing member 7, even if the needle of the syringe is removed, the airtightness can be made difficult to be impaired.
  • the closing member 7 may be removed from the second opening 3c and an aspirator may be connected to the second opening 3c. Thereby, the recovery rate of the mixture remaining in the casing 1 can be increased.
  • the substance mixing apparatus 10 is disassembled. Specifically, the closing member 7 is removed from the second opening 3 c, the casing 1 is removed from the collection container 3, and the filter unit 5 is removed from the collection container 3. Further, the stirring bar 9 is also taken out from the collection container 3. Thereby, only the collection container 3 can be separated from the substance mixing apparatus 10. For this reason, it becomes easy to transfer the obtained mixture from the collection container 3 to another container.
  • the collection container 3 containing the mixture may be attached to a spray pump or the like as a spray device to spray the mixture. This makes it easy to use the mixture. Since the spraying device is attached to the recovery container 3 instead of the casing 1, it is preferable that the spraying device can be attached to the neck portion 3 a of the recovery container 3. In this case, the collection container 3 preferably has a compact shape as shown in FIG. 2 in order to facilitate carrying with the spray device attached.
  • the substance mixing apparatus 10 can quickly obtain a mixture simply by damaging the sealed ampoule 2 in the casing 1. That is, the substance to be mixed has a long time in the state of being sealed in the sealed ampoule 2. For this reason, there are almost no restrictions on the types of substances that can be sealed in the sealed ampoule 2, and the restrictions on the types can be relaxed as compared with the conventional case. Moreover, it is not necessary for the obtained mixture to contact the casing 1 for a long time. For this reason, even if the casing 1 is made of a material that is easily eroded by the mixture, durability that can withstand at least one use is obtained.
  • the substance to be mixed can be sealed in the sealed ampoule 2 until just before the mixture is obtained. For this reason, it is very effective in that a substance that easily deteriorates (for example, pharmaceuticals, nutrients, and cosmetic effect ingredients) can be stored without deterioration until immediately before use (for example, injection, drinking, application). is there. Furthermore, according to the present invention, the mixture can be obtained quickly, so that it is possible to reduce the time and effort required for the stabilization process when synthesizing other substances by mixing. It is possible to eliminate the addition of antioxidants and preservatives to the mixture, and to simplify the storage container for substances.
  • a substance that easily deteriorates for example, pharmaceuticals, nutrients, and cosmetic effect ingredients
  • the space in the casing 1 may be divided into a plurality of storage chambers. However, in this case, each accommodation room is connected to other accommodation rooms. That is, also in this case, it is not necessary to provide a partition wall or a weak seal portion in the casing 1.
  • the substance mixing device 10 is provided with the filter unit 5 between the casing 1 and the recovery container 3, so that the fragments of the sealed ampoule 2 enter the recovery container 3 from the casing 1. Is prevented. Thereby, the possibility that the fragments of the sealed ampoule 2 are mixed into the target mixture can be eliminated.
  • the gas may be removed as the target mixture. preferable.
  • the second opening 3 c provided in the collection container 3 is closed by the closing member 7.
  • the closing member 7 is made of an elastic material and can pierce a hollow needle-like object. Using this, while maintaining the airtightness of the space formed by the casing 1 and the recovery container 3, at least a part of the mixture recovered in the recovery container 3 is taken out, or other substances are mixed into the mixture. It becomes possible to do.
  • the substance enclosed in the sealed ampule 2 can be mixed by using the casing 1 and damaging the sealed ampule 2 in the casing 1. Therefore, only the casing 1 constitutes the present invention. Furthermore, the mixture in the casing 1 can be easily recovered by removing the damaged sealed ampoule 2 by filtering. Moreover, in the substance mixing apparatus 10 mentioned above, you may comprise only the casing 1 by replacing
  • the one in which the collection container 3 and the casing 1 are connected can be regarded as one large casing. That is, the portion of the large casing made of the flexible material corresponds to the casing 1, and the portion made of a relatively high rigidity material corresponds to the collection container 3. In this case, it is also possible to mix the substances by arranging the substances in the collection container 3 in advance and dropping the liquid from the casing 1 into the collection container 3. In other words, the large casing also functions as a dropping device.
  • FIG. 4 is a diagram showing a substance mixing apparatus related to an embodiment different from the above of the present invention.
  • This substance mixing apparatus 10 is of a type that can be equipped with a nebulizer 11 in addition to the configuration shown in FIG. Not only this embodiment but the 2nd opening part 3c may be provided in the upper surface of the collection container 3, and may be provided in a side surface.
  • the collection container 3 can be connected to the opening 1 a of the casing 1. And it has the filter part 5 arrange
  • the collection container 3 has a first opening 3b to which the opening 1a of the casing 1 is connected and a second opening 3c to which the sprayer 11 is attached.
  • the second opening 3c and the first opening 3b are openings provided at different positions.
  • the casing 1 may further include one or a plurality of sealed ampules in addition to the first sealed ampule 2a and the second sealed ampule 2b or 2c.
  • the mixture recovered in the recovery container 3 is sprayed through the sprayer 11.
  • the sprayer 11 is attached to the second opening 3c.
  • a nozzle that can discharge liquid instead of the sprayer 11 may be attached. In either case, the liquid mixture recovered in the recovery container 3 can be easily taken out of the container.
  • the stirrer 9 is an optional element, and the substance mixing apparatus 10 may not have the stirrer 9 when it is not necessary to expand the sales of the mixed liquid.
  • a preferred embodiment of the present invention has a check valve between the collection container 3 and the discharge port for discharging the mixed liquid to the outside. Since the substance mixing apparatus 10 of this aspect can prevent the situation where air enters into the collection container 3 from the discharge port, the situation where the mixed liquid is oxidized can be effectively prevented.
  • the substance mixing device 10 and the casing 1 of the present invention can be suitably used in the field of mixing a plurality of substances.

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Abstract

Disclosed is a substance mixing device that makes it possible to alleviate the restrictions on the types of substances that can be charged therein, and also disclosed is a casing employed in the same. A substance mixing device (10) comprises a casing (1) having an opening portion (1a). The casing (1) houses a sealed ampule (2a) and sealed ampules (2b, 2c), and the housing sections therefor are manufactured from a flexible material. A fluid is charged into the sealed ampule (2a), and a substance is charged into the sealed ampules (2b, 2c). In addition,  with the sealed ampule (2a) and sealed ampules (2b, 2c) housed in the casing (1), the sealed ampule (2a) and sealed ampules (2b, 2c) are ruptured. As a result, the fluid and the substance are mixed.

Description

物質混合装置,及び当該物質混合装置に用いるケーシングSubstance mixing apparatus and casing used for the substance mixing apparatus
 本発明は、アンプルに封入された物質を混合するための物質混合装置,及び当該物質混合装置に用いるケーシングに関する。 The present invention relates to a substance mixing apparatus for mixing substances enclosed in an ampule and a casing used for the substance mixing apparatus.
 たとえば2種類の液体を混合するために,複室容器が提案されている。複室容器は,樹脂製のパッケージの内部空間をたとえば2つに分けた構造をしており,2つに分けることで形成された2つの室内のそれぞれに,混合対象となる液体が封入される。そして,必要な時に,2つの室内を隔てる隔壁を破損させるか,又は隔壁部分をなす弱シール部分を剥離することで,2つの室内空間をつなげ,これにより,2種類の液体を混合させることができる(たとえば,下記特許文献1(特開2008-206686号公報)参照)。 For example, a multi-chamber container has been proposed to mix two kinds of liquids. The multi-chamber container has a structure in which the internal space of the resin package is divided into two, for example, and the liquid to be mixed is sealed in each of the two chambers formed by dividing the package into two. . Then, when necessary, the two partitions are separated from each other by damaging the partition that separates the two chambers, or by peeling off the weak seal portion that forms the partition, thereby mixing the two liquids. (For example, see Patent Document 1 (Japanese Patent Laid-Open No. 2008-206686) below).
 しかしながら,上述したような複室容器は,樹脂製であるため,封入可能な液体の種類が制限される。具体的には,樹脂や弱シール部分を浸食するような液体を複室容器に長期間にわたって封入することはできない。 However, since the multi-chamber container as described above is made of resin, the types of liquid that can be sealed are limited. Specifically, it is not possible to enclose liquids that erode the resin and weakly sealed portions in a multi-chamber container for a long period of time.
 また,上記複室容器では,2種類の液体を混合させるために,隔壁を破損させるか,又は弱シール部分を剥離する必要がある。このため,複室容器を再利用することができない。
特開2008-206686号公報
Moreover, in the said multi-chamber container, in order to mix two types of liquid, it is necessary to break a partition or to peel a weak seal part. For this reason, the multi-chamber container cannot be reused.
JP 2008-206686 A
 本発明は,封入可能な物質の種類の制限を緩和することができる物質混合装置,及び当該物質混合装置に用いるケーシングを提供することを第1の目的とする。 The first object of the present invention is to provide a substance mixing device capable of relaxing restrictions on the types of substances that can be sealed, and a casing used for the substance mixing apparatus.
 また,本発明は,再利用可能な物質混合装置,及び当該物質混合装置に用いるケーシングを提供することを第2の目的とする。 The second object of the present invention is to provide a reusable substance mixing apparatus and a casing used for the substance mixing apparatus.
 本発明は,基本的には,物質を混合させて混合物を得る物質混合装置10に関する。本発明の物質混合装置10は,柔軟性材料製のケーシング1を備えている。このケーシング1は,開口部1aを有する。そして,このケーシング1には,複数の密封アンプル2が収容される。ここで,複数の密封アンプル2は,いずれも破損性を有する。密封アンプル2を破損させることにより,密封アンプル2に封入された流体と物質とが混合し,その結果,流動性のある混合物を得ることができる。 The present invention basically relates to a substance mixing apparatus 10 that obtains a mixture by mixing substances. The substance mixing apparatus 10 of the present invention includes a casing 1 made of a flexible material. The casing 1 has an opening 1a. A plurality of sealed ampules 2 are accommodated in the casing 1. Here, all of the plurality of sealed ampules 2 have breakability. By breaking the sealed ampule 2, the fluid and the substance enclosed in the sealed ampule 2 are mixed, and as a result, a fluid mixture can be obtained.
 すなわち,本発明の物質混合装置10では,ケーシング1内で,密封アンプル2を破損させるだけで,混合物を迅速に得ることが可能である。すなわち,混合対象となる流体や物質は,密封アンプル2に封入された状態にある時間が長い。このため,密封アンプル2に封入可能な物質の種類にはほとんど制限がなく,従来よりも種類の制限を緩和できることとなる。また,得られた混合物がケーシング1に長期間にわたって接触する必要がない。このため,ケーシング1が,たとえ混合物により浸食されやすい材料で構成されていたとしても,少なくとも1回の使用に耐えうる耐久性が得られることとなる。 That is, in the substance mixing apparatus 10 of the present invention, the mixture can be obtained quickly by simply damaging the sealed ampoule 2 in the casing 1. That is, the fluid or substance to be mixed has a long time in the state of being sealed in the sealed ampoule 2. For this reason, there are almost no restrictions on the types of substances that can be sealed in the sealed ampoule 2, and the restrictions on the types can be relaxed as compared with the conventional case. Moreover, it is not necessary for the obtained mixture to contact the casing 1 for a long time. For this reason, even if the casing 1 is made of a material that is easily eroded by the mixture, durability that can withstand at least one use is obtained.
 また,本発明の物質混合装置10では,ケーシング1内の空間を2つに分ける必要がない。つまり,ケーシング1に隔壁を設けたり,弱シール部分を設けたりする必要がない。このため,ケーシング1が劣化しない限りは,再利用することが可能となる。 In the substance mixing apparatus 10 of the present invention, it is not necessary to divide the space in the casing 1 into two. That is, it is not necessary to provide a partition wall or a weak seal portion on the casing 1. For this reason, as long as the casing 1 does not deteriorate, it can be reused.
 さらに,本発明の物質混合装置10は,回収容器3を備えており,ケーシング1と回収容器3との間に,フィルター部5が配置されることが好ましい。これにより,破損させた密封アンプル2がケーシング1から回収容器3に進入することが防止される。これにより,目的とする混合物に,破損させた密封アンプル2が混入するおそれをなくすことができる。 Furthermore, it is preferable that the substance mixing apparatus 10 of the present invention includes the recovery container 3, and the filter unit 5 is disposed between the casing 1 and the recovery container 3. This prevents the damaged sealed ampoule 2 from entering the recovery container 3 from the casing 1. Thereby, the possibility that the damaged sealed ampoule 2 is mixed into the target mixture can be eliminated.
 また,本発明の物質混合装置10では,回収容器3の側面に設けられた別の開口部3cが閉塞部材7によって塞がれている。ここで,閉塞部材7は弾性材料製であり,中空針状物を刺しこむことが可能である。これを利用して,ケーシング1及び回収容器3で形成される空間の気密性を維持しつつ,回収容器3内に回収された混合物の少なくとも一部を取り出したり,混合物に他の物質を混合させたりすることが可能となる。 Further, in the substance mixing device 10 of the present invention, another opening 3 c provided on the side surface of the recovery container 3 is closed by the closing member 7. Here, the closing member 7 is made of an elastic material and can pierce a hollow needle-like object. Using this, while maintaining the airtightness of the space formed by the casing 1 and the recovery container 3, at least a part of the mixture recovered in the recovery container 3 is taken out, or other substances are mixed into the mixture. It becomes possible to do.
 さらに,本発明の物質混合装置10においては,撹拌子9を用いて,回収容器3内に回収した混合物を撹拌してもよい。さらに,本発明の物質混合装置10は,回収容器3に装着可能な噴霧装置をさらに含むことが好ましい。この噴霧装置は,ケーシング1に代えて回収容器3に装着される。そして,この噴霧装置は,回収容器3内に回収された混合物を噴霧可能である。これにより,これにより,混合物を手軽に利用できるようになる。また,上述したケーシング1は,開口部1aを一端として長手方向に長い部材であり,複数の収容室,たとえば第1収容室と第2収容室を含んでいることが好ましい。ここで,第1収容室は,ケーシングの長手方向の一端(開口部1a側)に配置されており,第1収容室につながる第2収容室は,長手方向の他端側に配置される。第1収容室及び第2収容室には,密封アンプル2が収容される。これにより,密封アンプル2の収容場所が容易に分かる。このため,収容室を選ぶ順序で,物質の混合順序を調整することができる。 Furthermore, in the substance mixing apparatus 10 of the present invention, the mixture collected in the collection container 3 may be stirred using the stirring bar 9. Furthermore, it is preferable that the substance mixing device 10 of the present invention further includes a spray device that can be attached to the collection container 3. This spraying device is attached to the collection container 3 instead of the casing 1. The spray device can spray the mixture collected in the collection container 3. This makes it easier to use the mixture. The casing 1 described above is a member that is long in the longitudinal direction with the opening 1a as one end, and preferably includes a plurality of storage chambers, for example, a first storage chamber and a second storage chamber. Here, the first storage chamber is arranged at one end (opening 1a side) in the longitudinal direction of the casing, and the second storage chamber connected to the first storage chamber is arranged at the other end side in the longitudinal direction. The sealed ampule 2 is accommodated in the first accommodation chamber and the second accommodation chamber. Thereby, the accommodation place of the sealed ampoule 2 can be easily understood. For this reason, the mixing order of substances can be adjusted in the order of selecting the storage chambers.
 また,本発明の別の側面は,上記物質混合装置10に用いるケーシング1と同等の機能を有するケーシングである。これにより,上記物質混合装置10に用いるのに好適なケーシングが提供できる。 Further, another aspect of the present invention is a casing having a function equivalent to that of the casing 1 used in the substance mixing apparatus 10. Thereby, a casing suitable for use in the substance mixing apparatus 10 can be provided.
 本発明によれば,封入可能な物質の種類の制限を緩和することができる物質混合装置10を提供できる。また,本発明によれば,再利用可能な物質混合装置10を提供できる。さらに,本発明によれば,当該物質混合装置10に用いるのに好適なケーシング1を提供できる。 According to the present invention, it is possible to provide the substance mixing apparatus 10 that can relax the restriction on the types of substances that can be sealed. Further, according to the present invention, a reusable substance mixing apparatus 10 can be provided. Furthermore, according to the present invention, a casing 1 suitable for use in the substance mixing apparatus 10 can be provided.
図1は,本発明の物質混合装置の構成を概略的に示す正面図である。FIG. 1 is a front view schematically showing the configuration of the substance mixing apparatus of the present invention. 図2は,図1に示す回収容器の別の形状の例を説明するために用いる図である。FIG. 2 is a diagram used for explaining an example of another shape of the collection container shown in FIG. 図3は,図1の物質混合装置の使用時の状態の一例を説明するために用いる図である。FIG. 3 is a diagram used for explaining an example of a state when the substance mixing apparatus of FIG. 1 is used. 図4は,本発明の上記とは別の実施態様に関連する物質混合装置を示す図である。FIG. 4 is a view showing a substance mixing apparatus according to another embodiment of the present invention.
 以下,図面を用いて本発明を実施するための最良の形態を説明する。しかしながら,以下説明する形態はある例であって,当業者にとって自明な範囲で適宜修正することができる。 Hereinafter, the best mode for carrying out the present invention will be described with reference to the drawings. However, the form described below is an example, and can be appropriately modified within a range obvious to those skilled in the art.
 図1は,本発明の物質混合装置10の構成を概略的に示す正面図である。本発明の物質混合装置10は,複数の密封アンプル2(たとえば,後述する2a,2b,2c)に封入された物質を混合させて流動性のある混合物を得るためのものである。図1に示す物質混合装置10は,ケーシング1を備えている。また,この物質混合装置10は,さらに,回収容器3と,フィルター部5と,閉塞部材7と,撹拌子9とを含んで構成されている。 FIG. 1 is a front view schematically showing a configuration of a substance mixing apparatus 10 of the present invention. The substance mixing apparatus 10 of the present invention is for obtaining a fluid mixture by mixing substances sealed in a plurality of sealed ampules 2 (for example, 2a, 2b, 2c described later). A substance mixing apparatus 10 shown in FIG. 1 includes a casing 1. The substance mixing apparatus 10 further includes a collection container 3, a filter unit 5, a closing member 7, and a stirrer 9.
 ここで,密封アンプル2としては,破損性を有するものを用いることができ,たとえばガラス製のものを挙げることができる。なお,密封アンプル2は,ガラス製に限られることはなく,脆性(もろさ)を有する材料製であればよい。また,密封アンプル2の破損性を高めるためには,密封アンプル2は,長尺状であることが好ましい。また,密封アンプル2の破損性を高めるために,密封アンプル2に切り込みや溝を形成することで,部分的に厚みが異なる部分を設けてもよい。このようにすることで,脆性のない材料(たとえば樹脂材料)であっても,密封アンプル2の構成材料とすることができる。 Here, as the sealed ampoule 2, a damaging one can be used, for example, a glass one. The sealed ampoule 2 is not limited to glass but may be made of a material having brittleness (fragility). Further, in order to enhance the breakability of the sealed ampoule 2, the sealed ampoule 2 is preferably long. Further, in order to enhance the breakability of the sealed ampoule 2, a portion having a partially different thickness may be provided by forming a cut or a groove in the sealed ampoule 2. By doing in this way, even if it is a material (for example, resin material) which is not brittle, it can be used as the constituent material of the sealing ampoule 2.
 ケーシング1は,柔軟性(可撓性)材料製であり,たとえば,PP(ポリプロピレン),PET(ポリエチレンテレフタレート)などの樹脂材料で構成される。このように,ケーシング1を柔軟性材料で構成することにより,伸縮変形させることができる。なお,ケーシング1は,全体が柔軟性材料で構成されている必要はなく,少なくとも,密封アンプル2を収容する部分が柔軟性材料で構成されていればよい。ケーシング1の一部を柔軟性材料で構成するとともに,残りの部分を相対的に剛性の高い材料で構成することにより,変形しやすい場所を局所的にすることができ,これにより,部分的な折り曲げやひねりなどが容易になる。また,ケーシング1は,中空円柱状の袋形状をなしており,長手方向の長さがたとえば100mmである。そして,このケーシング1は,その一端に,開口部1aを有する。この開口部1aは,密封アンプル2の出し入れと,混合物の回収の際に用いられる。なお,ケーシング1は,後述するように,複数の収容室を有していてもよい。 The casing 1 is made of a flexible material, and is made of a resin material such as PP (polypropylene) or PET (polyethylene terephthalate). In this way, the casing 1 can be stretched and deformed by being made of a flexible material. Note that the casing 1 does not need to be entirely made of a flexible material, and at least a portion for accommodating the sealed ampoule 2 only needs to be made of a flexible material. A part of the casing 1 is made of a flexible material, and the remaining part is made of a material having a relatively high rigidity, thereby making it possible to localize an easily deformable place. Bending and twisting are easy. The casing 1 has a hollow cylindrical bag shape, and the length in the longitudinal direction is, for example, 100 mm. And this casing 1 has the opening part 1a in the end. The opening 1a is used when the sealed ampoule 2 is taken in and out and the mixture is recovered. The casing 1 may have a plurality of storage chambers as will be described later.
 ケーシング1の長さの例は,1cm以上20cm以下であり,2cm以上10cm以下でもよく,3cm以上7cm以下でもよい。ケーシング1のうち柔軟性材料により柔軟性を有する部分は,人力によりケーシング1を折り曲げることができる柔軟性のある部分である。一方,ケーシング1全体が柔軟性材料により製造されていても,その全てが柔軟性を有している必要はない。たとえば,ケーシング1の側面のみ可とう性を有していてもよい。 Examples of the length of the casing 1 are 1 cm or more and 20 cm or less, 2 cm or more and 10 cm or less, or 3 cm or more and 7 cm or less. A portion of the casing 1 that is flexible by the flexible material is a flexible portion that can be bent by the human power. On the other hand, even if the entire casing 1 is made of a flexible material, it is not necessary for all of the casing 1 to have flexibility. For example, only the side surface of the casing 1 may have flexibility.
 回収容器3は,本態様では,図1に示すように,上部に比べて下部が広いボトル形状をなしており,上部にはネック部3aが設けられている。回収容器3の形状として,ボトル形状を採用することで,回収容器3が転倒しにくくなる。また,回収容器3を構成する材料は,たとえばPET(ポリエチレンテレフタレート)である。これにより,軽量化を図ることができる。また,PETは成形性に優れているので大量生産が可能である。なお,回収容器3を構成する材料は,PETなどの樹脂材料に限られることはなく,たとえば,ガラスなどの耐久性のある材料であってもよい。また,回収容器3の形状は,ボトル形状に限られることはない。たとえば,図2に示すように,回収容器3の形状を,ネック部3aを除く部分が同径の筒形状とすることで,コンパクトにすることができ,これにより,持ちやすくすることができる。 As shown in FIG. 1, the collection container 3 is shaped like a bottle whose lower part is wider than the upper part, and a neck part 3 a is provided at the upper part. By adopting a bottle shape as the shape of the collection container 3, the collection container 3 is unlikely to fall down. The material constituting the collection container 3 is, for example, PET (polyethylene terephthalate). Thereby, weight reduction can be achieved. Moreover, since PET is excellent in moldability, it can be mass-produced. In addition, the material which comprises the collection container 3 is not restricted to resin materials, such as PET, For example, durable materials, such as glass, may be sufficient. Further, the shape of the collection container 3 is not limited to the bottle shape. For example, as shown in FIG. 2, the shape of the collection container 3 can be made compact by making the portion excluding the neck portion 3a the same diameter, thereby making it easier to hold.
 この回収容器3のネック部3aは,上方に向かって開口する,円形の第1の開口部3bを有する。このネック部3aには,上記ケーシング1の開口部の近傍をその柔軟性により引き伸ばして覆うことで,上記ケーシング1の第1の開口部3bを接続することが可能である。これにより,ケーシング1の開口部1aと,回収容器3の第1の開口部3bとが互いにつながることになる。また,その接続部は,ケーシング1の柔軟性によって密封される。すなわち,接続部は,液体の漏出や液体や気体の進入が起こりにくい構造となっている。 The neck 3a of the collection container 3 has a circular first opening 3b that opens upward. The first opening 3b of the casing 1 can be connected to the neck 3a by extending and covering the vicinity of the opening of the casing 1 with its flexibility. Thereby, the opening 1a of the casing 1 and the first opening 3b of the recovery container 3 are connected to each other. Further, the connecting portion is sealed by the flexibility of the casing 1. That is, the connection portion has a structure in which liquid leakage and liquid or gas entry are unlikely to occur.
 フィルター部5は,ケーシング1と回収容器3との間に配置される。このフィルター部5は,少なくとも1つのフィルターを含んでおり,このフィルターは,通過しようとする物質のうち,そのフィルターのメッシュよりも大きな物質の通過させないようにするとともに,メッシュよりも小さな物質を通過させるようになっている。フィルター部5を構成するフィルターは,目的とする混合物の流動性(粘性)に応じて適宜選択されることが好ましい。たとえば粘性が高い混合物である場合には,フィルターの厚みを大きくしたり,フィルターの剛性を高くしたりすることで,フィルターの損傷を抑止することが好ましい。また,フィルターを湾曲させて中央部に凹部又は凸部を設けることで,相対的に低くなる部分に,メッシュよりも大きな物質を集めてもよい。これにより,メッシュの目詰まりが防止できるとともに,フィルターが損傷しやすい部分を狭くすることができる。 The filter unit 5 is disposed between the casing 1 and the collection container 3. This filter unit 5 includes at least one filter, and this filter prevents a substance larger than the mesh of the filter from passing through, and passes a substance smaller than the mesh. It is supposed to let you. The filter constituting the filter unit 5 is preferably selected as appropriate according to the fluidity (viscosity) of the target mixture. For example, in the case of a highly viscous mixture, it is preferable to prevent damage to the filter by increasing the thickness of the filter or increasing the rigidity of the filter. Further, a material larger than the mesh may be collected in a relatively low portion by curving the filter and providing a concave portion or a convex portion in the central portion. As a result, clogging of the mesh can be prevented and the portion where the filter is easily damaged can be narrowed.
 本態様では,上記フィルター部5は,図1に示すように,フィルター内蔵型穴あきゴム栓5aと,シールフィルター5bとを含んでいる。穴あきゴム栓5aは,テーパー面を有する円柱形状をなすゴム製の栓に,その円柱の軸方向に沿って複数の貫通穴を設け,貫通穴の上方にフィルターを配置したものである。なお,栓はゴム製でなくてもよい。この穴あきゴム栓5aは,図1に示すように,第1の開口部3bに嵌め合わされている。また,シールフィルター5bは,たとえばメッシュの細かい樹脂製材料(たとえばTPE(熱可塑性エラストマー))で構成されており,図1に示すように,回収容器3のネック部3aの端部と,第1の開口部3bに嵌め合わされた穴あきゴム栓5aの双方を覆うように配置される。なお,シールフィルター5bに代えて,金属製や樹脂製の焼結フィルター,又は濾紙を用いてもよい。 In this embodiment, the filter unit 5 includes a filter built-in type perforated rubber stopper 5a and a seal filter 5b as shown in FIG. The perforated rubber stopper 5a is a rubber stopper having a tapered surface, provided with a plurality of through holes along the axial direction of the cylinder, and a filter disposed above the through holes. The stopper need not be made of rubber. As shown in FIG. 1, the perforated rubber stopper 5a is fitted into the first opening 3b. The seal filter 5b is made of, for example, a fine mesh resin material (for example, TPE (thermoplastic elastomer)). As shown in FIG. 1, the end of the neck 3a of the collection container 3 and the first It arrange | positions so that both of the perforated rubber stoppers 5a fitted to the opening 3b may be covered. Instead of the seal filter 5b, a sintered filter made of metal or resin, or filter paper may be used.
 さらに,回収容器3の側面には,第1の開口部3bとは別に,円形の第2の開口部3cが設けられている。本態様では,第2の開口部3cは,上方に向かって開口している。なお,第2の開口部3cは,側方に向かって開口していてもよい。この第2の開口部3cは,本発明の物質混合装置10で得られる混合物を回収する際に使用される。さらに,第2の開口部3cは,ケーシング1と回収容器3とを接続したときに,ケーシング1と回収容器3とで形成される空間の圧力を調整する際にも使用される。たとえば,回収容器3の圧力を低くするために,第2の開口部3cにアスピレーターを接続してもよい。 Furthermore, a circular second opening 3c is provided on the side surface of the collection container 3 separately from the first opening 3b. In the present embodiment, the second opening 3c opens upward. In addition, the 2nd opening part 3c may be opened toward the side. This 2nd opening part 3c is used when collect | recovering the mixture obtained with the substance mixing apparatus 10 of this invention. Furthermore, the second opening 3c is also used when adjusting the pressure of the space formed by the casing 1 and the recovery container 3 when the casing 1 and the recovery container 3 are connected. For example, an aspirator may be connected to the second opening 3c in order to reduce the pressure in the collection container 3.
 閉塞部材7は,上記第2の開口部3cを塞ぐための部材である。これにより,第2の開口部3cが密封される。閉塞部材7としては,ゴム栓,コルク栓,キャップ(一重),二重キャップ,伸縮性のあるフィルムなどを用いることができる。ところで,二重キャップは,中空円筒状をなす部材の内周側の略中央部に隔壁を設けた部材である。二重キャップの一端を開口部に嵌め込み,他端を一端側に折り返すように変形させることで,隔壁が外側に露出するようになっている。 The closing member 7 is a member for closing the second opening 3c. Thereby, the 2nd opening part 3c is sealed. As the closing member 7, a rubber plug, a cork plug, a cap (single), a double cap, a stretchable film, or the like can be used. By the way, the double cap is a member provided with a partition wall at a substantially central portion on the inner peripheral side of a hollow cylindrical member. One end of the double cap is fitted into the opening, and the other end is deformed so as to be folded back to the one end side, so that the partition wall is exposed to the outside.
 図1に示す例では,閉塞部材7として,第2の開口部3cと相補的な形状をなすキャップを用いている。そして,このキャップには,中空針状物を刺しこむことが可能である。中空針状物としては,たとえばシリンジ(注射器,インジェクター)の針を挙げることができる。そして,シリンジの針を刺しこむことで,回収容器3内に物質を注入したり,回収容器3から物質の一部を抽出したりすることができる。このように中空針状物を刺しこむ場合には,閉塞部材7は,弾性材料製であることが好ましい。これにより,中空針状物を刺しこんだ後に抜き出しても,穴が塞がりやすくなり,第2の開口部3cにおける気密性を維持することができる。 In the example shown in FIG. 1, a cap having a shape complementary to the second opening 3 c is used as the closing member 7. A hollow needle-like object can be inserted into the cap. Examples of the hollow needle-like material include a syringe (injector, injector) needle. By inserting the needle of the syringe, the substance can be injected into the collection container 3 or a part of the substance can be extracted from the collection container 3. When the hollow needle-like object is inserted in this way, the closing member 7 is preferably made of an elastic material. Thereby, even if the hollow needle-like object is inserted and extracted, the hole is easily closed, and the airtightness in the second opening 3c can be maintained.
 撹拌子9は,液状の混合物を撹拌させる際に,回収容器3内に入れて用いられるものであり,撹拌子9として,図1に示す例では,球状体を2つ用いている。これにより,回収容器3を移動させるだけで,撹拌子9が回収容器3の底面上を転がるように移動する。ここで,回収容器3内に流動性を有する混合物があれば,当該混合物も撹拌子9の移動にともなって撹拌される。なお,撹拌子9としては,球状体以外のものを用いてもよい。この場合,撹拌子9に磁石などを内蔵し,外部からの磁力で駆動することで撹拌子9の移動をスムーズに行うことが好ましい。また,撹拌子9の出し入れを可能にするために,上記第1の開口部3b及び上記第2の開口部3cの少なくとも一方のサイズを,撹拌子9のサイズとクリアランスとを考慮して決めることが好ましい。より好ましくは,少なくとも上記第2の開口部3cのサイズを,撹拌子9のサイズとクリアランスとを考慮して決める。これにより,回収容器3とケーシング1とが接続されても,回収容器3に撹拌子9を入れたり,回収容器3から撹拌子9を出したりすることが確実にできる。 The stirring bar 9 is used by being put in the collection container 3 when stirring the liquid mixture. In the example shown in FIG. 1, two spherical bodies are used as the stirring bar 9. Thereby, the stirrer 9 moves so as to roll on the bottom surface of the recovery container 3 only by moving the recovery container 3. Here, if there is a fluid mixture in the collection container 3, the mixture is also agitated as the stirrer 9 moves. In addition, as the stirring bar 9, you may use things other than a spherical body. In this case, it is preferable to move the stirrer 9 smoothly by incorporating a magnet or the like in the stirrer 9 and driving it with an external magnetic force. In order to allow the stirrer 9 to be taken in and out, the size of at least one of the first opening 3b and the second opening 3c is determined in consideration of the size of the stirrer 9 and the clearance. Is preferred. More preferably, at least the size of the second opening 3c is determined in consideration of the size of the stirring bar 9 and the clearance. Thereby, even if the collection container 3 and the casing 1 are connected, it is possible to reliably put the stirring bar 9 in the collection container 3 and take out the stirring bar 9 from the collection container 3.
 続いて,上述したような構成要素を含む物質混合装置10の使用方法について説明する。まず,物質混合装置10は,図1に示すように組み立てられていない状態から説明する。 Subsequently, a method of using the substance mixing apparatus 10 including the components as described above will be described. First, the substance mixing apparatus 10 will be described from a state where it is not assembled as shown in FIG.
 まず,混合対象となる物質が必要量だけ封入された密封アンプル2を,混合対象となる物質の種類の数だけ(たとえば3本)用意する。ここで,混合対象となる物質のうち,少なくとも1種類は流体であり,図1に示す例では,密封アンプル2aに封入されている。また,混合対象となる他の物質は,当該流体に分散又は溶解する固体,液体,及び,該流体に可溶性のある気体からなる群から選択され,図1に示す例では,密封アンプル2b,2cに封入されている。混合対象となる物質は,速やかに混合物が得られ,かつ外気に向かって拡散しないという点で,液体同士が最も好ましい。 First, a sealed ampoule 2 in which a necessary amount of a substance to be mixed is enclosed is prepared for the number of types of substances to be mixed (for example, three). Here, at least one of the substances to be mixed is a fluid, and in the example shown in FIG. 1, it is enclosed in a sealed ampoule 2a. Further, the other substance to be mixed is selected from the group consisting of a solid, a liquid that is dispersed or dissolved in the fluid, and a gas that is soluble in the fluid. In the example shown in FIG. 1, the sealed ampules 2b and 2c are selected. Is enclosed. The substances to be mixed are most preferably liquids in that a mixture is obtained quickly and does not diffuse toward the outside air.
 密封アンプル2は,たとえば,中空のガラスパイプを用意し,その中空部に封入対象の物質を配置し,ガラスパイプの開口端を熱などにより,塞ぐことで用意することができる。封入対象の物質が液体である場合や,熱に弱い物質である場合には,開口端が1つのガラス材を用意してもよい。また,封入対象の物質が紫外線に強い場合には,ガラス製のセルを用意し,セルとセル用のキャップとを紫外線硬化性樹脂で接合することで密封アンプル2を用意してもよい。また,市販の物質封入済みの密封アンプル2を用意してもよい。 The sealed ampoule 2 can be prepared, for example, by preparing a hollow glass pipe, placing a substance to be sealed in the hollow portion, and closing the open end of the glass pipe with heat or the like. If the material to be sealed is a liquid or a material that is weak against heat, a glass material having one open end may be prepared. When the substance to be sealed is strong against ultraviolet rays, a sealed cell ampule 2 may be prepared by preparing a glass cell and bonding the cell and the cell cap with an ultraviolet curable resin. Further, a commercially available sealed ampoule 2 encapsulating a substance may be prepared.
 続いて,用意した全ての密封アンプル2を物質混合装置10のケーシング1に開口部を介して入れる。混合対象の物質のうち,密封アンプル2に封入する必要のない物質があれば,ケーシング1や回収容器3に直接入れてもよい。そして,フィルター部5が設けられた回収容器3を用意し,回収容器3とケーシング1とを接続する。図1に示す例では,ケーシング1に収容された3本の密封アンプル2a,2b,2cが隠れ線(破線)で示されている。また,回収容器3には,撹拌子9が投入され,投入後,回収容器3の第2の開口部3cが閉塞部材7によって気密に覆われている。なお,第2の開口部3cを閉塞部材7で覆う前に,ケーシング1及び回収容器3によって形成される空間内部の空気を,所望の気体に置換してもよいし,アスピレーターなどを用いて脱気してもよい。なお,置換に用いる気体としては,アルゴン(Ar)や窒素(N2)などの不活性ガスを挙げることができる。また,混合対象に気体がある場合には,置換に用いる気体として,混合対象である気体を充満させてもよい。 Subsequently, all the prepared sealed ampules 2 are put into the casing 1 of the substance mixing apparatus 10 through the openings. Among the substances to be mixed, if there is a substance that does not need to be sealed in the sealed ampoule 2, it may be put directly into the casing 1 or the collection container 3. And the collection container 3 provided with the filter part 5 is prepared, and the collection container 3 and the casing 1 are connected. In the example shown in FIG. 1, three sealed ampoules 2a, 2b, 2c accommodated in the casing 1 are indicated by hidden lines (broken lines). Further, the stirrer 9 is introduced into the collection container 3, and after the introduction, the second opening 3 c of the collection container 3 is airtightly covered with the closing member 7. Before covering the second opening 3c with the closing member 7, the air inside the space formed by the casing 1 and the recovery container 3 may be replaced with a desired gas, or removed using an aspirator or the like. You may care. As the gas used for the substitution, mention may be made of argon (Ar) and nitrogen (N 2) an inert gas, such as. In addition, when there is a gas in the mixing target, the gas that is the mixing target may be filled as the gas used for the replacement.
 次に,ケーシング1内に収容した密封アンプル2を破損させる。具体的には,密封アンプル2をケーシング1の外部から間接的に手で握り,折ればよい。ここで,ケーシング1の材料として,柔軟性を有する材料を用いているため,密封アンプル2を容易に破損させることができるだけでなく,手で握ってもけがをするおそれがない。 Next, the sealed ampoule 2 housed in the casing 1 is broken. Specifically, the sealed ampoule 2 may be grasped by hand indirectly from the outside of the casing 1 and folded. Here, since a material having flexibility is used as the material of the casing 1, not only can the sealed ampoule 2 be easily broken, but there is no risk of injury even if it is grasped by hand.
 なお,密封アンプル2の破損は,遠隔操作によって行ってもよい。遠隔操作の具体例としては,ケーシング1が折り曲がったりケーシング1にひねりが生じたりするようにケーシング1に対して外的圧力を加えること,又は,ケーシング1内の気圧を低くすること,外部から密封アンプル2に対して振動(超音波)などを印加することなどを挙げることができる。これにより,人が立ち会うことなく,混合物を得ることも可能となる。したがって,本発明は,クリーンルームなどの人が立ち入ることができない場所で混合物を得ることが可能である点で有効である。また,同様に,人体に有害な物質などを,人が立ち会うことなく調製することもできる。 Note that the sealed ampoule 2 may be damaged by remote control. As a specific example of remote operation, external pressure is applied to the casing 1 so that the casing 1 bends or the casing 1 is twisted, or the pressure inside the casing 1 is lowered, or from the outside. For example, vibration (ultrasonic wave) or the like may be applied to the sealed ampoule 2. This makes it possible to obtain a mixture without human presence. Therefore, the present invention is effective in that the mixture can be obtained in a place where a person such as a clean room cannot enter. Similarly, substances that are harmful to the human body can be prepared without human attendance.
 そして,密封アンプル2に封入されていた物質は,ケーシング1内に拡散し,混合物となる。ところで,複数の密封アンプル2を破損させて複数の物質を混合するにあたり,その混合順序が問題となる場合がある。このような場合には,密封アンプル2を破損させる順序で混合順序を調整することが可能である。このためには,ケーシング1は,透明材料で構成することが好ましく,これにより,複数の密封アンプル2をケーシング1の外部から見分けることができる。 The substance enclosed in the sealed ampoule 2 diffuses into the casing 1 and becomes a mixture. By the way, when mixing a plurality of substances by damaging the plurality of sealed ampoules 2, the mixing order may become a problem. In such a case, it is possible to adjust the mixing order in the order in which the sealed ampoule 2 is broken. For this purpose, the casing 1 is preferably made of a transparent material, whereby the plurality of sealed ampoules 2 can be distinguished from the outside of the casing 1.
 より好ましくは,ケーシング1において,密封アンプル2を1つずつセット可能な収容室を長手方向に沿って並ぶように複数設ける。これにより,密封アンプル2の収容場所が容易に分かる。このため,収容室を選ぶ順序で,物質の混合順序を調整することができる。具体例を挙げると,ケーシング1は,その長手方向の一端に配置されて開口部1aにつながる第1収容室と,第1収容室につながる第2収容室とを少なくとも含んでおり,第1収容室には,固体物質が封入された密封アンプル2bが収容され,第2収容室には,液体が封入された密封アンプル2aが収容されている。そして,鉛直方向下方にある密封アンプル2bを先に破損させ,その後に,密封アンプル2aを破損させることで,固体物質を液体で溶解させながら流下させることができる。つまり,固体物質がケーシング1に残留しにくくなる。又は,必要に応じて,鉛直方向上方にある密封アンプル2を下方にある密封アンプル2よりも先に破損させてもよい。なお,ケーシング1に3つ以上の収容室を設けるには,第2収容室につながるように収容室をケーシング1の長手方向の他端側に設ければよい。 More preferably, in the casing 1, a plurality of storage chambers in which the sealed ampules 2 can be set one by one are provided so as to be arranged along the longitudinal direction. Thereby, the accommodation place of the sealed ampoule 2 can be easily understood. For this reason, the mixing order of substances can be adjusted in the order of selecting the storage chambers. As a specific example, the casing 1 includes at least a first storage chamber disposed at one end in the longitudinal direction and connected to the opening 1a, and a second storage chamber connected to the first storage chamber. The chamber contains a sealed ampule 2b in which a solid substance is enclosed, and the second accommodation chamber contains a sealed ampule 2a in which a liquid is enclosed. Then, the sealed ampoule 2b located in the lower part in the vertical direction is first broken, and then the sealed ampoule 2a is broken, so that the solid substance can flow down while being dissolved in the liquid. That is, it becomes difficult for the solid substance to remain in the casing 1. Alternatively, if necessary, the sealed ampoule 2 at the upper side in the vertical direction may be broken before the sealed ampoule 2 at the lower side. In order to provide three or more storage chambers in the casing 1, the storage chambers may be provided on the other end side in the longitudinal direction of the casing 1 so as to be connected to the second storage chamber.
 さらには,この混合物は,ケーシング1内から,フィルター部5を介して,下方にある回収容器3に移動する。このとき,フィルター部5は,密封アンプル2a,2b,2cの破片が回収容器3に進入することを防止する。これにより,混合物だけを回収することができる。なお,混合対象の物質に気体が含まれる場合には,柔軟性を有するケーシング1を押しつぶすことで回収容器3側に移動させることができる。 Furthermore, the mixture moves from the casing 1 through the filter unit 5 to the collection container 3 below. At this time, the filter unit 5 prevents the fragments of the sealed ampules 2a, 2b, 2c from entering the collection container 3. As a result, only the mixture can be recovered. In addition, when gas is contained in the substance to be mixed, the casing 1 having flexibility can be crushed and moved to the collection container 3 side.
 回収容器3側では,撹拌子9を用いて混合物を撹拌させる。これにより,混合物における混合比のばらつきをなくすことができる。また,このとき,シリンジの針を閉塞部材7に刺しこみ,混合物に他の物質を混合させる(添加する)ことができる。図3には,シリンジの針を閉塞部材7に刺しこんだときの状態が示されている。同様にシリンジの針を閉塞部材7に刺しこみ,混合物の一部を,たとえば分析用に取り出すことができる。閉塞部材7として弾性材料を用いているので,シリンジの針を抜きとっても,気密性が損なわれにくくすることができる。また,気密性を維持する必要がない場合には,閉塞部材7を第2の開口部3cから取り外して,第2の開口部3cにアスピレーターを接続してもよい。これにより,ケーシング1内に残留する混合物の回収率を高めることができる。 At the collection container 3 side, the mixture is stirred using the stirring bar 9. Thereby, the dispersion | variation in the mixing ratio in a mixture can be eliminated. At this time, the needle of the syringe can be inserted into the closing member 7 to mix (add) another substance to the mixture. FIG. 3 shows a state when the needle of the syringe is inserted into the closing member 7. Similarly, a syringe needle can be inserted into the closure member 7 and a portion of the mixture can be removed for analysis, for example. Since an elastic material is used as the closing member 7, even if the needle of the syringe is removed, the airtightness can be made difficult to be impaired. When it is not necessary to maintain airtightness, the closing member 7 may be removed from the second opening 3c and an aspirator may be connected to the second opening 3c. Thereby, the recovery rate of the mixture remaining in the casing 1 can be increased.
 そして,最終的に,目的とする混合物が得られたら,物質混合装置10を解体する。具体的には,閉塞部材7を第2の開口部3cから取り外し,ケーシング1を回収容器3から取り外し,さらに,回収容器3からフィルター部5を取り外す。また,回収容器3内から撹拌子9も取り出す。これにより,回収容器3のみを物質混合装置10から分離できる。このため,得られた混合物を回収容器3から別の容器に移すことも容易になる。 Finally, when the target mixture is obtained, the substance mixing apparatus 10 is disassembled. Specifically, the closing member 7 is removed from the second opening 3 c, the casing 1 is removed from the collection container 3, and the filter unit 5 is removed from the collection container 3. Further, the stirring bar 9 is also taken out from the collection container 3. Thereby, only the collection container 3 can be separated from the substance mixing apparatus 10. For this reason, it becomes easy to transfer the obtained mixture from the collection container 3 to another container.
 また,混合物が入った回収容器3を,噴霧装置としてのスプレーポンプなどに装着して,混合物を噴霧してもよい。これにより,混合物を手軽に利用できるようになる。噴霧装置は,ケーシング1の代わりに回収容器3に装着されるものであるから,回収容器3のネック部3aに装着可能なものが好ましい。また,この場合,回収容器3は,噴霧装置を装着した状態での持ち運びを容易にするために,図2に示したように,コンパクトな形状のものが好ましい。 Further, the collection container 3 containing the mixture may be attached to a spray pump or the like as a spray device to spray the mixture. This makes it easy to use the mixture. Since the spraying device is attached to the recovery container 3 instead of the casing 1, it is preferable that the spraying device can be attached to the neck portion 3 a of the recovery container 3. In this case, the collection container 3 preferably has a compact shape as shown in FIG. 2 in order to facilitate carrying with the spray device attached.
 上述した態様によれば,物質混合装置10は,ケーシング1内で,密封アンプル2が破損するだけで,混合物を迅速に得ることが可能である。すなわち,混合対象となる物質は,密封アンプル2に封入された状態にある時間が長い。このため,密封アンプル2に封入可能な物質の種類にはほとんど制限がなく,従来よりも種類の制限を緩和できることとなる。また,得られた混合物がケーシング1に長期間にわたって接触する必要がない。このため,ケーシング1が,たとえ混合物により浸食されやすい材料で構成されていたとしても,少なくとも1回の使用に耐えうる耐久性が得られることとなる。また,本発明の物質混合装置10によれば,混合物を得る直前まで,密封アンプル2に混合対象の物質を封入しておくことができる。このため,劣化しやすい物質(たとえば,医薬品,栄養素,美容効果成分)を,使用(たとえば,注射,飲用,塗布)の直前まで,劣化させることなく保存することができるという点で非常に有効である。さらには,本発明によれば,混合物を迅速に得ることができるので,混合により他の物質を合成する際に必要な安定化処理にかかる手間を軽減することができたり,従来は必要であった混合物への酸化防止剤や防腐剤などの添加を排除することができたり,物質の保存容器の簡素化を実現できたりする。 According to the above-described embodiment, the substance mixing apparatus 10 can quickly obtain a mixture simply by damaging the sealed ampoule 2 in the casing 1. That is, the substance to be mixed has a long time in the state of being sealed in the sealed ampoule 2. For this reason, there are almost no restrictions on the types of substances that can be sealed in the sealed ampoule 2, and the restrictions on the types can be relaxed as compared with the conventional case. Moreover, it is not necessary for the obtained mixture to contact the casing 1 for a long time. For this reason, even if the casing 1 is made of a material that is easily eroded by the mixture, durability that can withstand at least one use is obtained. Moreover, according to the substance mixing apparatus 10 of the present invention, the substance to be mixed can be sealed in the sealed ampoule 2 until just before the mixture is obtained. For this reason, it is very effective in that a substance that easily deteriorates (for example, pharmaceuticals, nutrients, and cosmetic effect ingredients) can be stored without deterioration until immediately before use (for example, injection, drinking, application). is there. Furthermore, according to the present invention, the mixture can be obtained quickly, so that it is possible to reduce the time and effort required for the stabilization process when synthesizing other substances by mixing. It is possible to eliminate the addition of antioxidants and preservatives to the mixture, and to simplify the storage container for substances.
 また,上述した態様によれば,ケーシング1内の空間を完全に2つに分ける必要がない。つまり,ケーシング1に隔壁を設けたり,弱シール部分を設けたりする必要がない。このため,ケーシング1が劣化しない限りは,再利用することが可能となる。なお,密封アンプル2のセットを容易にするため,及び/又は物質の混合順序を調整するために,ケーシング1内の空間を,複数の収容室に分けてもよい。ただし,この場合には,各収容室は他の収容室とつながっている。つまり,この場合にも,ケーシング1に隔壁を設けたり,弱シール部分を設けたりする必要がない。 Further, according to the above-described aspect, it is not necessary to completely divide the space in the casing 1 into two. That is, it is not necessary to provide a partition wall or a weak seal portion on the casing 1. For this reason, as long as the casing 1 does not deteriorate, it can be reused. In order to facilitate the setting of the sealed ampoule 2 and / or to adjust the mixing order of the substances, the space in the casing 1 may be divided into a plurality of storage chambers. However, in this case, each accommodation room is connected to other accommodation rooms. That is, also in this case, it is not necessary to provide a partition wall or a weak seal portion in the casing 1.
 さらに,上述した態様によれば,物質混合装置10には,ケーシング1と回収容器3との間にフィルター部5が設けられているので,密封アンプル2の破片がケーシング1から回収容器3に進入することが防止される。これにより,目的とする混合物に密封アンプル2の破片が混入するおそれをなくすことができる。ただし,混合物がその自重によってフィルター部5を通過する場合(つまり,図1に示すように,ケーシング1の下方に回収容器3を設ける場合)には,目的とする混合物として,気体を除くことが好ましい。 Further, according to the above-described aspect, the substance mixing device 10 is provided with the filter unit 5 between the casing 1 and the recovery container 3, so that the fragments of the sealed ampoule 2 enter the recovery container 3 from the casing 1. Is prevented. Thereby, the possibility that the fragments of the sealed ampoule 2 are mixed into the target mixture can be eliminated. However, when the mixture passes through the filter part 5 by its own weight (that is, when the collection container 3 is provided below the casing 1 as shown in FIG. 1), the gas may be removed as the target mixture. preferable.
 また,上述した態様によれば,回収容器3に設けられた第2の開口部3cが閉塞部材7によって塞がれている。ここで,閉塞部材7は弾性材料製であり,中空針状物を刺しこむことが可能である。これを利用して,ケーシング1及び回収容器3で形成される空間の気密性を維持しつつ,回収容器3内に回収された混合物の少なくとも一部を取り出したり,混合物に他の物質を混合させたりすることが可能となる。 Further, according to the above-described aspect, the second opening 3 c provided in the collection container 3 is closed by the closing member 7. Here, the closing member 7 is made of an elastic material and can pierce a hollow needle-like object. Using this, while maintaining the airtightness of the space formed by the casing 1 and the recovery container 3, at least a part of the mixture recovered in the recovery container 3 is taken out, or other substances are mixed into the mixture. It becomes possible to do.
 なお,本発明は,ケーシング1を用い,ケーシング1内で密封アンプル2を破損させることで,密封アンプル2に封入された物質を混合させることができるものである。したがって,ケーシング1だけでも本発明を構成することとなる。さらに,ケーシング1内の混合物は,破損させた密封アンプル2をフィルタリングによって除去すれば容易に回収できる。また,上述した物質混合装置10において,ケーシング1以外(回収容器3)を耐久性のあるガラスなどで構成することで,ケーシング1のみを交換可能に構成してもよい。すなわち,ケーシング1のみでも単体取引の対象となり得るものであり,物質混合装置10に用いるのに好適なケーシングを提供できる。 In the present invention, the substance enclosed in the sealed ampule 2 can be mixed by using the casing 1 and damaging the sealed ampule 2 in the casing 1. Therefore, only the casing 1 constitutes the present invention. Furthermore, the mixture in the casing 1 can be easily recovered by removing the damaged sealed ampoule 2 by filtering. Moreover, in the substance mixing apparatus 10 mentioned above, you may comprise only the casing 1 by replacing | excluding the casing 1 (collection container 3) with durable glass. That is, only the casing 1 can be a target of a single transaction, and a casing suitable for use in the substance mixing apparatus 10 can be provided.
 また,本発明において,回収容器3とケーシング1とが接続された状態にあるものを,1つの大型ケーシングとしてとらえることも可能である。すなわち,大型ケーシングの柔軟性材料で構成された部分がケーシング1に相当し,比較的剛性の高い材料で構成された部分が回収容器3に相当する。この場合,回収容器3に物質を予め配置しておき,ケーシング1から回収容器3に液体を滴下していくことで,物質を混合することも可能である。つまり,大型ケーシングは,滴下装置としても機能する。 Further, in the present invention, the one in which the collection container 3 and the casing 1 are connected can be regarded as one large casing. That is, the portion of the large casing made of the flexible material corresponds to the casing 1, and the portion made of a relatively high rigidity material corresponds to the collection container 3. In this case, it is also possible to mix the substances by arranging the substances in the collection container 3 in advance and dropping the liquid from the casing 1 into the collection container 3. In other words, the large casing also functions as a dropping device.
 図4は,本発明の上記とは別の実施態様に関連する物質混合装置を示す図である。この物質混合装置10は,図1に示された構成に加え,噴霧器11を装着できるタイプのものである。この実施態様に限らず,第2の開口部3cは,回収容器3の上面に設けられても良いし,側面に設けても良い。回収容器3は,ケーシング1の開口部1aと接続可能である。そして,ケーシング1と回収容器3との間に配置されるフィルター部5を有する。なわち,ケーシング1内の混合液が,フィルター部5を介して,回収容器3内へ回収される。回収容器3は,ケーシング1の開口部1aが接続される第1の開口部3bと,噴霧器11が装着される第2の開口部3cとを有する。この実施態様では,第2の開口部3cと第1の開口部3bとは異なる位置に設けられた開口部である。ケーシング1は第1の密封アンプル2a及び第2の密封アンプル2b,又は2cのほかに,さらに1又は複数の密封アンプルを含んでいても良い。 FIG. 4 is a diagram showing a substance mixing apparatus related to an embodiment different from the above of the present invention. This substance mixing apparatus 10 is of a type that can be equipped with a nebulizer 11 in addition to the configuration shown in FIG. Not only this embodiment but the 2nd opening part 3c may be provided in the upper surface of the collection container 3, and may be provided in a side surface. The collection container 3 can be connected to the opening 1 a of the casing 1. And it has the filter part 5 arrange | positioned between the casing 1 and the collection containers 3. That is, the mixed liquid in the casing 1 is recovered into the recovery container 3 through the filter unit 5. The collection container 3 has a first opening 3b to which the opening 1a of the casing 1 is connected and a second opening 3c to which the sprayer 11 is attached. In this embodiment, the second opening 3c and the first opening 3b are openings provided at different positions. The casing 1 may further include one or a plurality of sealed ampules in addition to the first sealed ampule 2a and the second sealed ampule 2b or 2c.
 ケーシング1内の混合物を回収容器3内に回収する際に,フィルター部5により破損させた第1の密封アンプル2a及び破損させた第2の密封アンプル2b,2cが回収容器3に進入することを防止される。一方,回収容器3内に回収された混合物は,噴霧器11を介して噴霧される。 When the mixture in the casing 1 is recovered in the recovery container 3, the first sealed ampoule 2 a damaged by the filter unit 5 and the damaged second sealed ampoules 2 b and 2 c enter the recovery container 3. Is prevented. On the other hand, the mixture recovered in the recovery container 3 is sprayed through the sprayer 11.
 図4に示す例では,第2の開口部3cに噴霧器11が取り付けられている。しかしながら,たとえば,噴霧器11に替えて液体を放出できるノズルが取り付けられているものであっても構わない。いずれの場合も,回収容器3内に回収された混合液を容器外に簡単に取り出すことができることとなる。なお,攪拌子9は任意の要素であり,混合液を拡販する必要がない場合は,物質混合装置10が撹拌子9を有しなくても構わない。 In the example shown in FIG. 4, the sprayer 11 is attached to the second opening 3c. However, for example, a nozzle that can discharge liquid instead of the sprayer 11 may be attached. In either case, the liquid mixture recovered in the recovery container 3 can be easily taken out of the container. The stirrer 9 is an optional element, and the substance mixing apparatus 10 may not have the stirrer 9 when it is not necessary to expand the sales of the mixed liquid.
 また,特に図示しないが,回収容器3から,混合液を外部に放出する放出口までの間に逆止弁を有するものは本発明の好ましい態様である。この態様の物質混合装置10は,放出口から空気が回収容器3内に進入する事態を防止できるため,混合液が酸化等する事態を効果的に防止できる。 Although not particularly shown, a preferred embodiment of the present invention has a check valve between the collection container 3 and the discharge port for discharging the mixed liquid to the outside. Since the substance mixing apparatus 10 of this aspect can prevent the situation where air enters into the collection container 3 from the discharge port, the situation where the mixed liquid is oxidized can be effectively prevented.
 本発明の物質混合装置10及びケーシング1は,複数の物質を混合する分野で好適に利用されうる。 The substance mixing device 10 and the casing 1 of the present invention can be suitably used in the field of mixing a plurality of substances.
 1 ケーシング
 2,2a,2b,2c 密封アンプル
 3 回収容器
 3a ネック部
 3b,3c 開口部
 5 フィルター部
 5a フィルター内蔵型穴あきゴム栓
 5b シールフィルター
 7 閉塞部材
 9 撹拌子
10 物質混合装置
11 噴霧器
DESCRIPTION OF SYMBOLS 1 Casing 2, 2a, 2b, 2c Sealed ampoule 3 Collection container 3a Neck part 3b, 3c Opening part 5 Filter part 5a Filter built-in perforated rubber stopper 5b Seal filter 7 Closure member 9 Stirrer 10 Substance mixing apparatus 11 Sprayer

Claims (8)

  1.  開口部(1a)を有するケーシング(1)を備える物質混合装置(10)であって,
     前記ケーシング(1)は,少なくとも一部が柔軟性材料製であり,
     前記ケーシング(1)は,
      破損性を有する第1の密封アンプル(2a)と,破損性を有する第2の密封アンプル(2b,2c)とを,前記柔軟性材料により柔軟性のある部分において収容し,
     前記第1の密封アンプル(2a)及び前記第2の密封アンプル(2b,2c)を前記ケーシング(1)内に収容した状態で,前記第1の密封アンプル(2a)及び前記第2の密封アンプル(2b,2c)を破損させることにより,前記第1の密封アンプル(2a)に封入された流体と前記第2の密封アンプル(2b,2c)に封入された物質とを混合させて流動性のある混合物を得ることが可能な,
     物質混合装置(10)。
    A substance mixing device (10) comprising a casing (1) having an opening (1a),
    The casing (1) is at least partially made of a flexible material,
    The casing (1)
    A breakable first sealed ampoule (2a) and a breakable second sealed ampoule (2b, 2c) are accommodated in a flexible part by the flexible material;
    The first sealed ampoule (2a) and the second sealed ampoule with the first sealed ampoule (2a) and the second sealed ampoule (2b, 2c) accommodated in the casing (1). By damaging (2b, 2c), the fluid sealed in the first sealed ampoule (2a) and the substance sealed in the second sealed ampoule (2b, 2c) are mixed to produce fluidity. A mixture can be obtained,
    Substance mixing device (10).
  2.  前記物質混合装置(10)は,さらに,
      前記ケーシング(1)の開口部(1a)と接続可能な回収容器(3)と,
      前記ケーシング(1)と前記回収容器(3)との間に配置されるフィルター部(5)と,
     を含み,
     前記ケーシング(1)内の混合物を前記回収容器(3)内に回収する際に,前記フィルター部(5)により前記破損させた第1の密封アンプル(2a)及び前記破損させた第2の密封アンプル(2b,2c)が前記回収容器(3)に進入することを防止する,
     請求項1に記載の物質混合装置(10)。
    The substance mixing device (10) further comprises:
    A collection container (3) connectable to the opening (1a) of the casing (1);
    A filter part (5) disposed between the casing (1) and the recovery container (3);
    Including
    When the mixture in the casing (1) is recovered in the recovery container (3), the damaged first sealed ampoule (2a) and the damaged second sealed are sealed by the filter part (5). Preventing the ampules (2b, 2c) from entering the collection container (3),
    The substance mixing device (10) according to claim 1.
  3.  前記回収容器(3)は,
      前記ケーシング(1)の開口部(1a)が接続される第1の開口部(3b)と,
      前記回収容器(3)に設けられる第2の開口部(3c)と,
     を含み,
     前記物質混合装置(10)は,
      前記回収容器(3)の前記第2の開口部(3c)を塞ぐ,弾性材料製の閉塞部材(7)をさらに備え,
     前記閉塞部材(7)に中空針状物を刺しこむことで,前記ケーシング(1)及び前記回収容器(3)で形成される空間の気密性を維持しつつ,前記回収容器(3)内に回収された混合物の少なくとも一部を取り出すか,又は前記混合物に他の物質を混合させることが可能な,
     請求項2に記載の物質混合装置(10)。
    The collection container (3)
    A first opening (3b) to which the opening (1a) of the casing (1) is connected;
    A second opening (3c) provided in the recovery container (3);
    Including
    The substance mixing device (10)
    A closing member (7) made of an elastic material for closing the second opening (3c) of the recovery container (3);
    By inserting a hollow needle-like object into the closing member (7), the airtightness of the space formed by the casing (1) and the recovery container (3) is maintained, and the inside of the recovery container (3) is maintained. It is possible to take out at least a part of the recovered mixture or to allow the mixture to mix with other substances,
    Substance mixing device (10) according to claim 2.
  4.  前記回収容器(3)の前記第1の開口部(3b)及び前記第2の開口部(3c)の少なくとも一方のサイズは,
      撹拌子(9)の出し入れが可能なサイズであり,
     前記回収容器(3)内に入れた前記撹拌子(9)を用いて,前記混合物を撹拌させることが可能な,
     請求項3に記載の物質混合装置(10)。
    The size of at least one of the first opening (3b) and the second opening (3c) of the collection container (3) is:
    The size of the stirring bar (9) can be taken in and out,
    The mixture can be stirred using the stirring bar (9) placed in the recovery container (3).
    4. A substance mixing device (10) according to claim 3.
  5.  前記物質混合装置(10)は,前記回収容器(3)に装着可能な噴霧装置をさらに含み,
     前記噴霧装置は,前記ケーシング(1)に代えて前記回収容器(3)に装着されることで,前記回収容器(3)内に回収された前記混合物を噴霧可能である,
     請求項2~請求項4のいずれか1項に記載の物質混合装置。
    The substance mixing device (10) further includes a spraying device attachable to the recovery container (3),
    The spray device is capable of spraying the mixture recovered in the recovery container (3) by being attached to the recovery container (3) instead of the casing (1).
    The substance mixing apparatus according to any one of claims 2 to 4.
  6.  前記ケーシング(1)は,
      前記開口部(1a)を一端として長手方向に長い部材であるとともに,
      前記長手方向の前記一端に配置された第1収容室と,
      前記長手方向の他端側に配置され,前記第1収容室につながる第2収容室とを含み,
     前記第1収容室は,前記第1の密封アンプル(2a)及び前記第2の密封アンプル(2b,2c)の一方を収容し,
     前記第2収容室は,前記第1の密封アンプル(2a)及び前記第2の密封アンプル(2b,2c)の他方を収容する,
     請求項1~請求項5のいずれか1項に記載の物質混合装置(10)。
    The casing (1)
    The opening (1a) is a member that is long in the longitudinal direction as one end,
    A first storage chamber disposed at the one end in the longitudinal direction;
    A second storage chamber disposed on the other end side in the longitudinal direction and connected to the first storage chamber;
    The first storage chamber stores one of the first sealed ampule (2a) and the second sealed ampule (2b, 2c),
    The second accommodating chamber accommodates the other of the first sealed ampule (2a) and the second sealed ampule (2b, 2c);
    The substance mixing device (10) according to any one of claims 1 to 5.
  7.  破損性を有する第1の密封アンプル(2a)と,破損性を有する第2の密封アンプル(2b,2c)とを収容するための開口部(1a)を有する柔軟性材料製のケーシング(1)であって,
     前記ケーシング(1)内に前記第1の密封アンプル(2a)及び前記第2の密封アンプル(2b,2c)を収容した状態で,前記第1の密封アンプル(2a)及び前記第2の密封アンプル(2b,2c)を破損させることにより,前記第1の密封アンプル(2a)に封入された流体と前記第2の密封アンプル(2b,2c)に封入された物質とを混合させて混合物を得ることが可能な,
     ケーシング(1)。
    A casing (1) made of a flexible material having an opening (1a) for accommodating the first sealed ampoule (2a) having breakability and the second sealed ampoule (2b, 2c) having breakage Because
    The first sealed ampoule (2a) and the second sealed ampoule in a state where the first sealed ampoule (2a) and the second sealed ampoule (2b, 2c) are accommodated in the casing (1). (2b, 2c) is broken to mix the fluid sealed in the first sealed ampoule (2a) with the substance sealed in the second sealed ampoule (2b, 2c) to obtain a mixture. Possible,
    Casing (1).
  8.  前記物質混合装置(10)は,さらに,
      前記ケーシング(1)の開口部(1a)と接続可能な回収容器(3)と,
      前記ケーシング(1)と前記回収容器(3)との間に配置されるフィルター部(5)と,
     を含み,
     前記回収容器(3)は,
      前記ケーシング(1)の開口部(1a)が接続される第1の開口部(3b)と,前記回収容器(3)に設けられ,噴霧器(11)が装着される第2の開口部(3c)とを有する回収容器であり,
     前記ケーシング(1)内の混合物を前記回収容器(3)内に回収する際に,前記フィルター部(5)により前記破損させた第1の密封アンプル(2a)及び前記破損させた第2の密封アンプル(2b,2c)が前記回収容器(3)に進入することを防止し,
     前記回収容器(3)内に回収した混合物を,前記噴霧器(11)を介して噴霧できる,
     請求項1に記載の物質混合装置(10)。
     
    The substance mixing device (10) further comprises:
    A collection container (3) connectable to the opening (1a) of the casing (1);
    A filter part (5) disposed between the casing (1) and the recovery container (3);
    Including
    The collection container (3)
    A first opening (3b) to which the opening (1a) of the casing (1) is connected, and a second opening (3c) provided in the collection container (3) and fitted with a sprayer (11). And a collection container having
    When the mixture in the casing (1) is recovered in the recovery container (3), the damaged first sealed ampoule (2a) and the damaged second sealed are sealed by the filter part (5). The ampoules (2b, 2c) are prevented from entering the collection container (3);
    The mixture recovered in the recovery container (3) can be sprayed through the sprayer (11).
    The substance mixing device (10) according to claim 1.
PCT/JP2009/005468 2008-10-22 2009-10-19 Substance mixing device, and casing employed in same WO2010047082A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008-271473 2008-10-22
JP2008271473 2008-10-22

Publications (1)

Publication Number Publication Date
WO2010047082A1 true WO2010047082A1 (en) 2010-04-29

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CN113242768A (en) * 2018-12-21 2021-08-10 水景有限公司 Box
CN115158889A (en) * 2022-09-05 2022-10-11 常州远望流体科技有限公司 Packaging bottle

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JPS62207468A (en) * 1986-02-26 1987-09-11 ヘキスト・アクチエンゲゼルシヤフト Apparatus for administering drug suspension
JPH0510257U (en) * 1991-07-17 1993-02-09 株式会社大阪製薬 Drug supply lid
JP2005530656A (en) * 2002-06-25 2005-10-13 アメリカ合衆国 Mixing vial
JP2005289518A (en) * 1995-06-07 2005-10-20 Sprayex Llc Rechargeable dispenser
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JP2007210683A (en) * 2007-02-06 2007-08-23 Masahiro Ishida Cream package body

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JPS62207468A (en) * 1986-02-26 1987-09-11 ヘキスト・アクチエンゲゼルシヤフト Apparatus for administering drug suspension
JPH0510257U (en) * 1991-07-17 1993-02-09 株式会社大阪製薬 Drug supply lid
JP2005289518A (en) * 1995-06-07 2005-10-20 Sprayex Llc Rechargeable dispenser
JP2005530656A (en) * 2002-06-25 2005-10-13 アメリカ合衆国 Mixing vial
JP2006001610A (en) * 2004-06-18 2006-01-05 Sumitomo Chemical Co Ltd Container for agricultural chemical
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JP2007210683A (en) * 2007-02-06 2007-08-23 Masahiro Ishida Cream package body

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113242768A (en) * 2018-12-21 2021-08-10 水景有限公司 Box
CN115158889A (en) * 2022-09-05 2022-10-11 常州远望流体科技有限公司 Packaging bottle
CN115158889B (en) * 2022-09-05 2022-11-29 常州远望流体科技有限公司 Packaging bottle

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