WO2010042639A2 - Système de décontamination et de dispersion à large spectre - Google Patents

Système de décontamination et de dispersion à large spectre Download PDF

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Publication number
WO2010042639A2
WO2010042639A2 PCT/US2009/059870 US2009059870W WO2010042639A2 WO 2010042639 A2 WO2010042639 A2 WO 2010042639A2 US 2009059870 W US2009059870 W US 2009059870W WO 2010042639 A2 WO2010042639 A2 WO 2010042639A2
Authority
WO
WIPO (PCT)
Prior art keywords
decontaminant
decontaminate
volume
accordance
donators
Prior art date
Application number
PCT/US2009/059870
Other languages
English (en)
Other versions
WO2010042639A3 (fr
Inventor
Jessie Kater
Original Assignee
L3 Communications Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by L3 Communications Corporation filed Critical L3 Communications Corporation
Publication of WO2010042639A2 publication Critical patent/WO2010042639A2/fr
Publication of WO2010042639A3 publication Critical patent/WO2010042639A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A62—LIFE-SAVING; FIRE-FIGHTING
    • A62D—CHEMICAL MEANS FOR EXTINGUISHING FIRES OR FOR COMBATING OR PROTECTING AGAINST HARMFUL CHEMICAL AGENTS; CHEMICAL MATERIALS FOR USE IN BREATHING APPARATUS
    • A62D3/00—Processes for making harmful chemical substances harmless or less harmful, by effecting a chemical change in the substances
    • A62D3/30—Processes for making harmful chemical substances harmless or less harmful, by effecting a chemical change in the substances by reacting with chemical agents
    • A62D3/38—Processes for making harmful chemical substances harmless or less harmful, by effecting a chemical change in the substances by reacting with chemical agents by oxidation; by combustion
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A—HUMAN NECESSITIES
    • A62—LIFE-SAVING; FIRE-FIGHTING
    • A62D—CHEMICAL MEANS FOR EXTINGUISHING FIRES OR FOR COMBATING OR PROTECTING AGAINST HARMFUL CHEMICAL AGENTS; CHEMICAL MATERIALS FOR USE IN BREATHING APPARATUS
    • A62D2101/00—Harmful chemical substances made harmless, or less harmful, by effecting chemical change
    • A62D2101/02—Chemical warfare substances, e.g. cholinesterase inhibitors

Definitions

  • the present invention relates to a substance for decontaminating toxins present in the air or on a surface.
  • RO x reactive species of oxygen
  • the present invention is a decontaminant designed to decontaminate one or more of a chemical agent (such as a chemical warfare agent) and a biological agent (such as a biopathogen).
  • a chemical agent such as a chemical warfare agent
  • a biological agent such as a biopathogen
  • the decontaminant utilizes a chemical activation agent, rather than energy from a plasma arc, ultraviolet light or other such energy source, to generate excess oxygen radicals. It is designed to work in an open environment (such as outdoors, rather than in an environmentally-controlled space) and at temperatures ranging from about -25°F to 125°F.
  • a decontaminant according to the invention can be used in many applications, including on irregular surfaces and/or to destroy toxins in the air.
  • the decontaminant includes: (i) a mixture of organic and aqueous liquids that solubilize toxins, and (ii) one or more activators that generate additional reactive oxygen species when reacted with an oxidizing agent, which hydrolyze (and thus decontaminate) toxins, and one or more oxidizing agents.
  • This decontaminant may be deployed utilizing any suitable method or device for one or both of surface decontamination and aerosol decontamination.
  • a decontaminant according to the invention can be formulated to meet the Joint Program Executive Office for Chemical and Biological Defense ("JPEO") requirements and be effective against chemical agents including nerve and blister agents (V class, G class and H class) as well as bacteria, viruses and other toxins. Additionally, it can be formulated to be effective over a temperature range of -25°F to 125°F.
  • JPEO Joint Program Executive Office for Chemical and Biological Defense
  • Solvent A decontaminant according to the invention may include an organic solvent to solubilize chemical agents (which typically have a non-polar matrix) and/or an aqueous solvent (preferably water) to solubilize biological agents (which typically are soluble in a polar, such as an aqueous, matrix).
  • the toxins are solubilized by the solvent in order to increase the efficiency of the decontamination.
  • the organic solvent is preferably one or more of ethanol, 2,3 butane diol, and 1-hexanol, although any suitable organic solvent(s) may be used.
  • a decontaminant according to the invention preferably includes one or more oxygen radical donators.
  • An oxygen radical donator (RO x ) that may be used with the invention can be hydrogen peroxide as a component of the starting mixture or hydrogen peroxide or other oxygen moieties generated via a chemical reaction, as understood by those skilled in the art. Other suitable oxygen radical donators may be used.
  • One or more activators are included in a decontaminant according to the invention.
  • the activators(s) generate additional reactive oxygen species when reacted with the one ore more oxygen radical donators (such as hydrogen peroxide).
  • hydrogen peroxide and the activator react to create peroxyacetic acid (PAA), which is an oxidizing agent.
  • a preferred activator is tetra acetyl ethylene diamine (TAED), although any suitable activator(s) may be used.
  • the activator(s) (sometimes referred to herein as a "dry activator”) is preferably dry and in a powder form. Buffer
  • One or more buffers may be used to increase the pH of the composition forming the decontaminant and the buffer is preferably NaOH provided in dry, powder form or in a 5.5Molar (M) solution.
  • the pH is preferably raised to at least about 6.8, most preferably to about 7.1-7.2, and preferably no higher than about 7.5, in order to better facilitate the reaction between the oxygen radical donator(s) and the activator(s).
  • the buffer may be any suitable material(s) for raising the pH to a desired level.
  • One or more oxidizing agents are included in a decontaminant according to the invention.
  • the oxidizing agent includes reactive oxygen species and is used to decontaminate the contaminant.
  • An oxidizing agent according to the invention may include PAA, although any suitable oxidizing agent(s) may be used.
  • the various constituents described above are shipped and stored in separate containers and mixed to form a decontaminant prior to use.
  • the constituents are shipped and stored in four containers, with one container including the solvent (preferably water and an organic solvent) and the oxygen radical donator (preferably hydrogen peroxide), one including the oxidizing agent (preferably PAA), one including a liquid activator (preferably 5.5 M NaOH) and one including the dry activator (preferably TAED).
  • the solvent preferably water and an organic solvent
  • the oxygen radical donator preferably hydrogen peroxide
  • PAA oxidizing agent
  • a liquid activator preferably 5.5 M NaOH
  • dry activator preferably TAED
  • a decontaminant according to the invention may be dispersed into the air or onto a surface and any suitable method or device may be utilized for this purpose. Any nozzle that generates relatively uniform particles that can remain suspended in the air may be used.
  • a preferred decontaminant according to the invention is set forth on the following page:
  • Table II Approximate Composition of the Decontaminant after mixing the constituents listed in Table I.
  • NaOH powder is preferably mixed in water to a total amount of 100 mL before placement into the decontaminant.
  • the alternative is to transport 100 mL of 5.5 Molar NaOH.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Pest Control & Pesticides (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Inorganic Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Business, Economics & Management (AREA)
  • Emergency Management (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La présente invention concerne une composition permettant de décontaminer une toxine se trouvant dans une matrice polaire ou non polaire. La composition comprend (a) au moins un activateur qui génère une espèce d’oxygène réactif lorsqu’il est mis à réagir avec un donneur de radical oxygène et (b) au moins un donneur de radical oxygène pour réagir avec l’activateur afin de créer une espèce d’oxygène réactif. La composition peut également inclure un ou plusieurs agents oxydants qui comprennent une espèce d’oxygène réactif.
PCT/US2009/059870 2008-10-08 2009-10-07 Système de décontamination et de dispersion à large spectre WO2010042639A2 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US10387808P 2008-10-08 2008-10-08
US61/103,878 2008-10-08
US10421308P 2008-10-09 2008-10-09
US61/104,213 2008-10-09
US12/471,231 US20120141598A1 (en) 2008-10-08 2009-05-22 Broad spectrum decontaminate and dispersement system
US12/471,231 2009-05-22

Publications (2)

Publication Number Publication Date
WO2010042639A2 true WO2010042639A2 (fr) 2010-04-15
WO2010042639A3 WO2010042639A3 (fr) 2011-04-21

Family

ID=42101189

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/059870 WO2010042639A2 (fr) 2008-10-08 2009-10-07 Système de décontamination et de dispersion à large spectre

Country Status (2)

Country Link
US (1) US20120141598A1 (fr)
WO (1) WO2010042639A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111357761A (zh) * 2018-12-26 2020-07-03 哈尔滨三联药业股份有限公司 过氧乙酸消毒剂及其应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3684477A (en) * 1969-08-28 1972-08-15 Fmc Corp Microorganism control
WO1994018297A1 (fr) * 1993-02-08 1994-08-18 Warwick International Group Limited Agents d'oxydation
US20030045767A1 (en) * 2000-01-04 2003-03-06 The United States Of America Chemical and biological warfare decontaminating solution using bleach activators
WO2003028429A2 (fr) * 2001-10-01 2003-04-10 Sandia Corporation Formulations ameliorees permettant de neutraliser des substances toxiques chimiques, biologiques et industrielles
WO2008079170A2 (fr) * 2006-08-15 2008-07-03 American Sterilizer Company Mélange de décontamination contenant des solides, monocomposant
WO2010059459A1 (fr) * 2008-11-20 2010-05-27 Aries Associates, Inc. Nouvelles chimies, solutions et systèmes de dispersion pour la décontamination de systèmes chimiques et biologiques

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITVR980033A1 (it) * 1998-04-30 1999-10-30 Farmec Di Tabasso Renato & C S Procedimento per l'ottenimento estemporaneo di un disinfettante a base di acido peracetico.
US20060128585A1 (en) * 2004-12-15 2006-06-15 Martha Adair Antimicrobial composition for cleaning substrate
ES2534471T3 (es) * 2006-10-27 2015-04-23 E.I. Du Pont De Nemours And Company Método para la descontaminación de priones
CN101675153B (zh) * 2007-05-04 2014-09-24 埃科莱布有限公司 含水溶性镁化合物的清洁组合物及其使用方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3684477A (en) * 1969-08-28 1972-08-15 Fmc Corp Microorganism control
WO1994018297A1 (fr) * 1993-02-08 1994-08-18 Warwick International Group Limited Agents d'oxydation
US20030045767A1 (en) * 2000-01-04 2003-03-06 The United States Of America Chemical and biological warfare decontaminating solution using bleach activators
WO2003028429A2 (fr) * 2001-10-01 2003-04-10 Sandia Corporation Formulations ameliorees permettant de neutraliser des substances toxiques chimiques, biologiques et industrielles
WO2008079170A2 (fr) * 2006-08-15 2008-07-03 American Sterilizer Company Mélange de décontamination contenant des solides, monocomposant
WO2010059459A1 (fr) * 2008-11-20 2010-05-27 Aries Associates, Inc. Nouvelles chimies, solutions et systèmes de dispersion pour la décontamination de systèmes chimiques et biologiques

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MARTIN DAVIES AND MICHAEL E DEARY D: "Kinetics of the hydrolysis and perhydrolysis of tetraacetylethylenediamine, a peroxide bleach activator", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 2, CHEMICAL SOCIETY. LETCHWORTH, GB, vol. 10, 1 January 1991 (1991-01-01), pages 1549-1552, XP009144558, ISSN: 1472-779X, DOI: DOI:10.1039/P29910001549 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111357761A (zh) * 2018-12-26 2020-07-03 哈尔滨三联药业股份有限公司 过氧乙酸消毒剂及其应用

Also Published As

Publication number Publication date
US20120141598A1 (en) 2012-06-07
WO2010042639A3 (fr) 2011-04-21

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