WO2010018438A3 - Tétrazoles glycosides - Google Patents

Tétrazoles glycosides Download PDF

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Publication number
WO2010018438A3
WO2010018438A3 PCT/IB2009/006497 IB2009006497W WO2010018438A3 WO 2010018438 A3 WO2010018438 A3 WO 2010018438A3 IB 2009006497 W IB2009006497 W IB 2009006497W WO 2010018438 A3 WO2010018438 A3 WO 2010018438A3
Authority
WO
WIPO (PCT)
Prior art keywords
tetrazole
glycosides
sglt2
sglt
transporter
Prior art date
Application number
PCT/IB2009/006497
Other languages
English (en)
Other versions
WO2010018438A2 (fr
Inventor
Bandi Parthasaradhi Reddy
Kura Rathnakar Reddy
Vedula Manohar Sharma
Musku Madhanmohan Reddy
Poshala Ramesh
Original Assignee
Hetero Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hetero Research Foundation filed Critical Hetero Research Foundation
Publication of WO2010018438A2 publication Critical patent/WO2010018438A2/fr
Publication of WO2010018438A3 publication Critical patent/WO2010018438A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des dérivés de tétrazoles glycosides qui sont des inhibiteurs du co-transporteur du glucose dépendant du sodium (SGLT), en particulier SGLT2, et des procédés de traitement de maladies, d'états et/ou de troubles inhibés par SGLT2 avec eux, et des procédés de préparation de ceux-ci.
PCT/IB2009/006497 2008-08-11 2009-08-05 Tétrazoles glycosides WO2010018438A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1934CH2008 2008-08-11
IN1934/CHE/2008 2008-08-11

Publications (2)

Publication Number Publication Date
WO2010018438A2 WO2010018438A2 (fr) 2010-02-18
WO2010018438A3 true WO2010018438A3 (fr) 2011-01-20

Family

ID=41669393

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/006497 WO2010018438A2 (fr) 2008-08-11 2009-08-05 Tétrazoles glycosides

Country Status (1)

Country Link
WO (1) WO2010018438A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108358863A (zh) * 2018-03-08 2018-08-03 湖北佰智昂生物化工有限公司 一种锌路易斯酸表面活性剂催化制备5′-取代四氮唑化合物的方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
WO2013037390A1 (fr) 2011-09-12 2013-03-21 Sanofi Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
EP2760862B1 (fr) 2011-09-27 2015-10-21 Sanofi Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221865B1 (en) * 1995-11-06 2001-04-24 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
WO2004073594A2 (fr) * 2003-02-12 2004-09-02 L'oreal Utilisation d’un inhibiteur de 15-hydroxy prostaglandine deshydrogenase pour favoriser la pigmentation de la peau ou des phaneres
WO2004099230A1 (fr) * 2003-05-12 2004-11-18 Fujisawa Pharmaceutical Co., Ltd. Composes de monosaccharide
WO2004106293A2 (fr) * 2003-05-21 2004-12-09 Bristol-Myers Squibb Company Composes tricycliques a base d'oxazolo[4,5-b]pyridine condensee a un imidazo et de thiazolo[4,5-b]pyridine condensee a un imidazo, et compositions pharmaceutiques renfermant ceux-ci
WO2005021566A2 (fr) * 2003-08-26 2005-03-10 Boehringer Ingelheim International Gmbh Pyrazoles glucopyranosyloxy, medicaments contenant ces composes, leur utilisation et leur procede de production
EP1637539A1 (fr) * 2003-06-20 2006-03-22 Kissei Pharmaceutical Co., Ltd. Derive de pyrazole, composition de medicaments contenant ledit derive et intermediaire de production associe
WO2006033001A1 (fr) * 2004-09-23 2006-03-30 Pfizer Products Inc. Composes de quinoline

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221865B1 (en) * 1995-11-06 2001-04-24 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
WO2004073594A2 (fr) * 2003-02-12 2004-09-02 L'oreal Utilisation d’un inhibiteur de 15-hydroxy prostaglandine deshydrogenase pour favoriser la pigmentation de la peau ou des phaneres
WO2004099230A1 (fr) * 2003-05-12 2004-11-18 Fujisawa Pharmaceutical Co., Ltd. Composes de monosaccharide
WO2004106293A2 (fr) * 2003-05-21 2004-12-09 Bristol-Myers Squibb Company Composes tricycliques a base d'oxazolo[4,5-b]pyridine condensee a un imidazo et de thiazolo[4,5-b]pyridine condensee a un imidazo, et compositions pharmaceutiques renfermant ceux-ci
EP1637539A1 (fr) * 2003-06-20 2006-03-22 Kissei Pharmaceutical Co., Ltd. Derive de pyrazole, composition de medicaments contenant ledit derive et intermediaire de production associe
WO2005021566A2 (fr) * 2003-08-26 2005-03-10 Boehringer Ingelheim International Gmbh Pyrazoles glucopyranosyloxy, medicaments contenant ces composes, leur utilisation et leur procede de production
WO2006033001A1 (fr) * 2004-09-23 2006-03-30 Pfizer Products Inc. Composes de quinoline

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANDREINI, F. ET AL: "Modification of the 1,2,3-triazole ring present in an effective in vitro inhibitor of prostaglandin synthesis", FARMACO , 44(9), 831 -41 CODEN: FRMCE8; ISSN: 0014-827X, 1989, XP002610493 *
HUISGEN, ROLF ET AL: "Ring opening of azoles. II. The formation of 1,3,4-oxadiazoles in the acylation of 5-substituted tetrazoles", CHEMISCHE BERICHTE , 93, 2106 -24 CODEN: CHBEAM; ISSN: 0009-2940, 1960, XP002610492 *
JEFFERSON W TILLEY ET AL: "Carboxylic Acids and Tetrazoles as Isosteric Replacements for Sulfate in Cholecystokinin Analogues", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, vol. 34, no. 3, 1 March 1991 (1991-03-01), pages 1125 - 1136, XP002413472, ISSN: 0022-2623, DOI: DOI:10.1021/JM00107A037 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108358863A (zh) * 2018-03-08 2018-08-03 湖北佰智昂生物化工有限公司 一种锌路易斯酸表面活性剂催化制备5′-取代四氮唑化合物的方法

Also Published As

Publication number Publication date
WO2010018438A2 (fr) 2010-02-18

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