WO2010006513A1 - Équipement portatif de diagnostic pour la lésion précancéreuse du cancer cervical - Google Patents

Équipement portatif de diagnostic pour la lésion précancéreuse du cancer cervical Download PDF

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Publication number
WO2010006513A1
WO2010006513A1 PCT/CN2009/070098 CN2009070098W WO2010006513A1 WO 2010006513 A1 WO2010006513 A1 WO 2010006513A1 CN 2009070098 W CN2009070098 W CN 2009070098W WO 2010006513 A1 WO2010006513 A1 WO 2010006513A1
Authority
WO
WIPO (PCT)
Prior art keywords
light source
cervical cancer
cervix
light
excitation light
Prior art date
Application number
PCT/CN2009/070098
Other languages
English (en)
Chinese (zh)
Inventor
曾堃
虞震芬
Original Assignee
Zeng Kun
Yu Zhen Fen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN 200810131630 external-priority patent/CN101322644B/zh
Application filed by Zeng Kun, Yu Zhen Fen filed Critical Zeng Kun
Priority to US13/054,415 priority Critical patent/US20110184272A1/en
Publication of WO2010006513A1 publication Critical patent/WO2010006513A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/012—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor characterised by internal passages or accessories therefor
    • A61B1/015—Control of fluid supply or evacuation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0607—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements for annular illumination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0661—Endoscope light sources
    • A61B1/0684—Endoscope light sources using light emitting diodes [LED]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/303—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the vagina, i.e. vaginoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells

Abstract

La présente invention concerne un équipement portatif de diagnostic (600) pour la lésion précancéreuse du cancer cervical comportant un système de détection par fluorescence incorporé (602) pour le cancer cervical, un système de détection de cancer cervical par coloration de l’acide acétique (604), et un système d’acquisition d’images (606). Le système de détection par fluorescence incorporé (602) comporte une source lumineuse (620) et un commutateur de source lumineuse (622). La source lumineuse (620) comporte une source lumineuse excitée qui fournit une fluorescence et une source lumineuse froide qui fournit une lumière blanche, et la source lumineuse excitée et la source lumineuse froide sont toutes les deux installées dans une coupelle de réflexion de lumière (624) avec un point focal déterminé. Le système de détection de cancer cervical par coloration de l’acide acétique (604) comporte un réservoir d’acide acétique (640), un conduit de pulvérisation (642) raccordé au réservoir d’acide acétique, un dispositif mobile (644) de conduit de pulvérisation et un interrupteur de pulvérisation (646). Le système d’acquisition d’images (606) comporte une caméra CCD à lumière faible (660), et la caméra CCD à lumière faible (660) est installée au centre de la coupelle de réflexion de lumière (624). Le système d’acquisition d’images (606) est connecté à un système de traitement d’images externe (700), et ledit système de traitement d’images externe (700) traite les images acquises par le système d’acquisition d’images (606).
PCT/CN2009/070098 2008-06-13 2009-01-12 Équipement portatif de diagnostic pour la lésion précancéreuse du cancer cervical WO2010006513A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/054,415 US20110184272A1 (en) 2008-06-13 2009-01-12 Portable Diagnostic Device for Precancerous Lesion of Cervical Cancer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN 200810131630 CN101322644B (zh) 2008-06-13 2008-07-15 便携式子宫颈癌癌前病变诊断装置
CN200810131630.7 2008-07-15

Publications (1)

Publication Number Publication Date
WO2010006513A1 true WO2010006513A1 (fr) 2010-01-21

Family

ID=41557467

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2009/070098 WO2010006513A1 (fr) 2008-06-13 2009-01-12 Équipement portatif de diagnostic pour la lésion précancéreuse du cancer cervical

Country Status (1)

Country Link
WO (1) WO2010006513A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5329938A (en) * 1983-02-17 1994-07-19 The Trylon Corporation Method for endoscopic examination of body cavity using chemilumine-scent light source
CN1302210A (zh) * 1997-10-20 2001-07-04 得克萨斯系统大学评议会 荧光分光术中以乙酸用作增强信号对比度试剂
CN1493250A (zh) * 2002-10-31 2004-05-05 ƽ 内窥镜诊断癌前病变的装置
CN1502305A (zh) * 2002-11-22 2004-06-09 上海生标科技有限公司 光活检癌前病变图像诊断仪
US20080039720A1 (en) * 2006-06-05 2008-02-14 Forth Photonics Ltd. Methods for characterizing cancer and pre-cancer tissues
CN101322644A (zh) * 2008-06-13 2008-12-17 曾堃 便携式子宫颈癌癌前病变诊断装置

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5329938A (en) * 1983-02-17 1994-07-19 The Trylon Corporation Method for endoscopic examination of body cavity using chemilumine-scent light source
CN1302210A (zh) * 1997-10-20 2001-07-04 得克萨斯系统大学评议会 荧光分光术中以乙酸用作增强信号对比度试剂
CN1493250A (zh) * 2002-10-31 2004-05-05 ƽ 内窥镜诊断癌前病变的装置
CN1502305A (zh) * 2002-11-22 2004-06-09 上海生标科技有限公司 光活检癌前病变图像诊断仪
US20080039720A1 (en) * 2006-06-05 2008-02-14 Forth Photonics Ltd. Methods for characterizing cancer and pre-cancer tissues
CN101322644A (zh) * 2008-06-13 2008-12-17 曾堃 便携式子宫颈癌癌前病变诊断装置

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