WO2010005146A1

WO2010005146A1 - Tablet containing acanthopanax sessiliflorus and vitamin and method manufacturing thereof

Info

Publication number: WO2010005146A1
Application number: PCT/KR2008/005463
Authority: WO
Inventors: Myong Won An
Original assignee: Ogapi Food Agricultural Union Corporation
Priority date: 2008-07-08
Filing date: 2008-09-17
Publication date: 2010-01-14

Abstract

The present invention relates to a tablet containing Acanthopanax sessiliflorus and vitamin and a preparing method thereof, more particularly to a tablet containing Acanthopanax sessiliflorus extract powder, vitamin C, vitamin B₁, vitamin B₂, vitamin B6, a sugar and an additive, and a preparing method thereof. The tablet containing Acanthopanax sessiliflorus and vitamin in accordance with the present invention provides maintenance and improvement of health through enhancement of physical functions, restoration of physiological functions, enhancement of immunity, recovery from fatigue, activation of metabolism, or the like, provided by Acanthopanax sessiliflorus. As Acanthopanax sessiliflorus and vitamin are prepared into a tablet using a sugar, it can be easily taken and carried by people of all ages and both sexes. Further, since Acanthopanax sessiliflorus is included in the form of extract powder, the characteristic flavor and odor of Acanthopanax sessiliflorus are mitigated.

Description

Invention Title

TABLET CONTAINING ACANTHOPANAX SESSILIFLORUS AND VITAMIN AND METHOD MANUFACTURING THEREOF

Technical Field

The present invention relates to a tablet containing Acanthopanax sessiliflorus and vitamin and a preparing method thereof, more particularly to a tablet containing Acanthopanax sessiliflorus extract powder, vitamin C, vitamin Bi, vitamin B₂, vitamin B₆, a sugar and an additive, and a preparing method thereof.

Background Art

Acanthopanax sessiliflorus is a deciduous broad-leaved shrub belonging to the Araliaceae family. It is a medicinal plant known to have the effects of enhancing overall physiological functions of organs, restoring pathologically changed physiological functions, enhancing immunity against diseases, facilitating metabolism of water, fat, sugar, etc., regulating body weight, or the like. Acanthopanax sessiliflorus contains useful ingredients such as eleutheroside, chiisanoside, sesamin, savinin, etc. as well as acanthoside, facilitates activation of physical functions and metabolism through improvement of physical constitution, refreshes the bloodstream, and revives cells. Accordingly, interests are increasing in the useful effects of Acanthopanax sessiliflorus and studies on drugs or foods containing Acanthopanax sessiliflorus are being carried out actively.

In spite of the above-described excellent effects of Acanthopanax sessiliflorus, Acanthopanax sessiliflorus is not favored by people due to its characteristic flavor and odor. Accordingly, it is needed to prepare Acanthopanax sessiliflorus to be taken and carried conveniently by people. Furthermore, a development of Acanthopanax sessiliflorus containing product for improvement of health by adding health-promoting ingredients is necessary.

Disclosure Technical Problem

Accordingly, an object of the present invention is to provide a tablet containing Acanthopanax sessiliflorus extract powder, vitamin C, vitamin Bi, vitamin B₂, vitamin B₆, a sugar and an additive, and a preparing method thereof.

Technical Solution

In an aspect, the present invention provides a tablet containing Acanthopanax sessiliflorus extract powder, vitamin C, vitamin B-i, vitamin B₂, vitamin B₆, a sugar and an additive.

In another aspect, the present invention provides a method for preparing a tablet containing Acanthopanax sessiliflorus and vitamin, including: (a) extracting the stem, leaf, fruit or root of Acanthopanax sessiliflorus using water or organic solvent; (b) filtering, concentrating and then drying the resultant extract; (c) grinding the resultant concentrated and dried extract to prepare Acanthopanax sessiliflorus extract powder; (d) mixing the resultant Acanthopanax sessiliflorus extract powder with vitamin C, vitamin Bi, vitamin B₂, vitamin B₆, a sugar and an additive; and (e) preparing the resultant mixture into a tablet.

Advantageous Effects

The tablet containing Acanthopanax sessiliflorus and vitamin in accordance with the present invention provides maintenance and improvement of health through enhancement of physical functions, restoration of physiological functions, enhancement of immunity, recovery from fatigue, activation of metabolism, or the like, provided by Acanthopanax sessiliflorus. As Acanthopanax sessiliflorus and vitamin are prepared into a tablet using a sugar, it can be easily taken and carried by people of all ages and both sexes. Further, since Acanthopanax sessiliflorus is included in the form of extract ^'powder, the characteristic flavor and odor of Acanthopanax sessiliflorus are mitigated. Description of Drawings

The above and other aspects, features and advantages of the disclosed exemplary embodiments will be more apparent from the following detailed description taken in conjunction with the accompanying drawing in which:

Fig. 1 is a flowchart illustrating a method for preparing a tablet containing Acanthopanax sessiliflonis and vitamin according to the present invention.

Best Mode

Exemplary embodiments now will be described more fully hereinafter with reference to the accompanying drawings, in which exemplary embodiments are shown. This disclosure may, however, be embodied in many different forms and should not be construed as limited to the exemplary embodiments set forth therein. Rather, these exemplary embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of this disclosure to those skilled in the art. In the description, details of well-known features and techniques may be omitted to avoid unnecessarily obscuring the presented embodiments. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of this disclosure. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. Furthermore, the use of the terms a, an, etc. does not denote a limitation of quantity, but rather denotes the presence of at least one of the referenced item. The use of the terms "first", "second", and the like does not imply any particular order, but they are included to identify individual elements. Moreover, the use of the terms first, second, etc. does not denote any order or importance, but rather the terms first, second, etc. are used to distinguish one element from another. It will be further understood that the terms "comprises" and/or "comprising", or "includes" and/or "including" when used in this specification, specify the presence of stated features, regions, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, regions, integers, steps, operations, elements, components, and/or groups thereof. Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the relevant art and the present disclosure, and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.

The present invention provides a tablet containing Acanthopanax sessiliflorus extract powder, vitamin C, vitamin Bi, vitamin B₂, vitamin B₆, a sugar and an additive.

Preferably, the Acanthopanax sessiliflonjs extract powder may be prepared by extracting one or more of the stem, leaf, fruit and root of Acanthopanax sessiliflorus using water or organic solvent, and concentrating and drying the same, although not limited thereto. Most preferably, it may be prepared in accordance with the procedures of (a) to (e) of the method for preparing a tablet containing Acanthopanax sessiliflorus and vitamin of the present invention. Preferably, the Acanthopanax sessiliflorus extract powder has a particle size of about 50 to 100 mesh, most preferably about 80 mesh, although not limited thereto (see <Example 1>). Preferably, the tablet containing Acanthopanax sessiliflorus and vitamin of the present invention may comprise 0.1 to 5.0 wt% of Acanthopanax sessiliflorus extract powder, 0.1 to 5.0 wt% of vitamin C, 0.001 to 0.01 wt% of vitamin B₁, 0.001 to 0.01 wt% of vitamin B₂, 0.001 to 0.01 wt% of vitamin B₆, 65.0 to 95.0 wt% of a sugar and 4.0 to 25.0 wt% of an additive, based on the total weight, although not limited thereto. Most preferably, the tablet containing Acanthopanax sessiliflorus and vitamin of the present invention may comprise 1.000 wt% of Acanthopanax sessiliflorus extract powder, 2.000 wt% of vitamin C, 0.004 wt% of vitamin Bi, 0.004 wt% of vitamin B₂, 0.004 wt% of vitamin B₆, 90.487 wt% of a sugar and 6.501 wt% of an additive, based on the total weight.

In particular, when the content of the Acanthopanax sessiliflorus extract powder exceeds the aforesaid range, the table may be inappropriate for taking because of the strong flavor and odor characteristic of Acanthopanax sessiliflorus. And, if it is included in an amount below the aforesaid range, the effect of Acanthopanax sessiliflorus may not be attained. Hence, the aforesaid range is preferred.

Vitamin B or vitamin C is included because they need to be taken on a daily basis since they are water-soluble and not stored in the body. Especially, since vitamin B provides sweet flavor and vitamin C provides sour flavor, in general, they can mitigate the characteristic flavor and odor of Acanthopanax sessiliflorus. In addition, the sugar may be added to further enhance the sweet flavor.

Preferably, the sugar may be one or more selected from a group consisting of lactose, glucose, xylitol, fructose, isomalt, sucralose, cellulose and erythritol, although not limited thereto. And, preferably, the additive may be one or more selected from a group consisting of enzymatically modified stevioside, magnesium stearate, organic acid calcium salt produced by fermentation, citric acid, folic acid, strawberry powder flavor, araliaceous flavor, strawberry flavor, yogurt flavor and whey calcium, although not limited thereto.

The present invention also provides a method for preparing a tablet containing Acanthopanax sessiliflorus and vitamin, comprising: (a) extracting the stem, leaf, fruit or root of Acanthopanax sessiliflorus using water or organic solvent; (b) filtering, concentrating and then drying the resultant extract; (c) grinding the resultant concentrated and dried extract to prepare Acanthopanax sessiliflorus extract powder; (d) mixing the resultant Acanthopanax sessiliflorus extract powder with vitamin C, vitamin Bi, vitamin B₂, vitamin B₆, a sugar and an additive; and (e) preparing the resultant mixture into a tablet. Hereinafter, the method for preparing a tablet containing Acanthopanax sessiliflorus and vitamin according to the present invention will be described in detail.

The extraction in (a) may be performed by extracting the stem, leaf, fruit or root of Acanthopanax sessiliflorus using water or organic solvent. Preferably, the organic solvent may be selected from a group consisting of methanol, ethanol, butanol, hexane and ethyl acetate, although not limited thereto. Most preferably, hot water extraction may be carried out using water. The water or organic solvent may be added in an amount of 8 to 12 times the total volume of the Acanthopanax sessiliflorus mixture, although not limited thereto. Most preferably, hot water extraction may be carried out by adding 10 times the volume of water and boiling at 100 ⁰C for 3 to 5 hours, preferably for 4 hours. In an embodiment of the present invention, the hot water extraction may be carried out by cutting the stem, leaf, fruit or root of Acanthopanax sessiliflorus to adequate size, immersing them in about 10 times the volume of water and boiling at 100 ⁰C for 4 hours (see <Example 1 -1 >).

The concentration and drying in (b) may be performed by filtering the Acanthopanax sessiliflorus extract extracted in (a) through a filter, and then concentrating and drying the same, according to a commonly employed method. Preferably, a cartridge filter may be used for the filtering, a continuous concentrator may be used for the concentration, and a vacuum dryer may be used for the drying, although not limited thereto. In an embodiment of the present invention, Acanthopanax sessiliflorus hot water extract may be filtered through a cartridge filter. Then, the filtrate may be concentrated using a continuous concentrator, and then dried using a vacuum dryer (see <Example 1-1>). The grinding in (c) may be performed by grinding the extract concentrated and dried in (b) using a commonly used grinder to prepare Acanthopanax sessiliflorus extract powder. Preferably, the Acanthopanax sessilifloms extract powder may have a particle size of about 50 to 100 mesh, most preferably about 80 mesh (see <Example 1-1 >), although not limited thereto.

The mixing in (d) may be performed by mixing the Acanthopanax sessilifloms extract powder prepared in (c) with vitamin C, vitamin Bi, vitamin B₂, vitamin B₆, a sugar and an additive.

Preferably, the mixing in (d) may be performed by mixing 0.1 to 5.0 wt% of

Acanthopanax sessiliflorus extract powder with 0.1 to 5.0 wt% of vitamin C,

0.001 to 0.01 wt% of vitamin Bi, 0.001 to 0.01 wt% of vitamin B₂, 0.001 to

0.01 wt% of vitamin B₆, 65.0 to 95.0 wt% of a sugar and 4.0 to 25.0 wt% of an additive, based on the total weight (see <Example 1-2>), although not limited thereto.

The tablet making in (e) may be performed by shaping and compressing the mixture prepared in (d) into a tablet (see <Example 1-2>).

The tablet containing Acanthopanax sessiliflorus and vitamin in accordance with the present invention provides maintenance and improvement of health through enhancement of physical functions, restoration of physiological functions, enhancement of immunity, recovery from fatigue, activation of metabolism, or the like, provided by Acanthopanax sessiliflorus. As Acanthopanax sessiliflorus and vitamin are prepared into a tablet using a sugar, it can be easily taken and carried by people of all ages and both sexes. Further, since Acanthopanax sessiliflorus is included in the form of extract powder, the characteristic flavor and odor of Acanthopanax sessiliflorus are mitigated.

Mode for Invention

The examples will now be described. The following examples are for illustrative purposes only and not intended to limit the scope of this disclosure.

Preparation of tablet containing Acanthopanax sessiliflorus and vitamin <1-1> Preparation of Acanthopanax sessiliflorus extract powder The stem, leaf, fruit or root of Acanthopanax sessiliflorus was cut to an adequate size, immersed in about 10 times the volume of water. Then, hot water extraction was performed at 100 ⁰C for 4 hours. The hot water extract was filtered through a cartridge filter. The filtrate was concentrated using a continuous concentrator and then dried using a vacuum dryer. The dried extract was ground using a commonly used grinder into fine powder having a final particle size of about 80 mesh.

<1-2> Preparation of tablet containing Acanthopanax sessiliflorus and vitamin

The Acanthopanax sessiliflorus extract powder prepared in <Example 1-1> was mixed with vitamin C, vitamin B-i, vitamin B2 and vitamin Be and prepared into a tablet containing Acanthopanax sessiliflorus and vitamin. Specifically, the Acanthopanax sessiliflorus extract powder, vitamin C, vitamin Bi, vitamin B₂ and vitamin B₆ were mixed at a proportion of 0.1 to 5.0 wt%, 0.1 to 5.0 wt%, 0.001 to 0.01 wt%, 0.001 to 0.01 wt% and 0.001 to 0.01 wt%, based on the total weight. Then, after adding 65.0 to 95.0 wt% of sugar and other additives, followed by mixing, the mixture was prepared into a tablet containing Acanthopanax sessiliflorus and vitamin. The sugar included lactose, glucose, xylitol, fructose, isomalt, sucralose, cellulose, erythritol, etc. and the additive included acidulant, flavor, etc. Specifically, enzymatically modified stevioside, magnesium stearate, organic acid calcium salt produced by fermentation, citric acid, folic acid, strawberry powder flavor, araliaceous flavor, strawberry flavor, yogurt flavor, whey calcium, etc. were used.

Preparation Example 1>

<1-1> Preparation of tablet containing Acanthopanax sessiliflorus and vitamin (I) [Table 1 ]

<1-2> Preparation of tablet containing Acanthopanax sessiliflonis and vitamin (II)

[Table 2]

<1-3> Preparation of tablet containing Acanthopanax sessiliflorυs and vitamin (III)

[Table 3]

Industrial Applicability

The tablet containing Acanthopanax sessiliflorus and vitamin in accordance with the present invention provides maintenance and improvement of health through enhancement of physical functions, restoration of physiological functions, enhancement of immunity, recovery from fatigue, activation of metabolism, or the like, provided by Acanthopanax sessiliflorus.

As Acanthopanax sessiliflorus and vitamin are prepared into a tablet using a sugar, it can be easily taken and carried by people of all ages and both sexes.

Further, since Acanthopanax sessiliflorus is included in the form of extract ^'powder, the characteristic flavor and odor of Acanthopanax sessiliflorus are mitigated.

Claims

CLAIMS Claim 1

A tablet containing Acanthopanax sessiliflorusa and vitamin comprising

Acanthopanax sessiliflorusa extract powder, vitamin C, vitamin Bi, vitamin B₂,

vitamin B₆, a sugar and an additive.

Claim 2

The tablet of Claim 1 , wherein the tablet comprising 0.1 to 5.0 wt% of

Acanthopanax sessiliflorus extract powder, 0.1 to 5.0 wt% of vitamin C, 0.001 to 0.01 wt% of vitamin B₁, 0.001 to 0.01 wt% of vitamin B₂, 0.001 to 0.01 wt% of vitamin B₆, 65.0 to 95.0 wt% of a sugar and 4.0 to 25.0 wt% of an additive, based on the total weight.

Claim 3 The tablet of Claim 1 , wherein the sugar comprising one or more selected from a group consisting of lactose, glucose, xylitol, fructose, isomalt, sucralose, cellulose and erythritol.

Claim 4 The tablet of Claim 1 , wherein the additive comprising one or more selected from a group consisting of enzymatically modified stevioside, magnesium stearate, organic acid calcium salt produced by fermentation, citric acid, folic acid, strawberry powder flavor, araliaceous flavor, strawberry flavor, yogurt flavor and whey calcium.

Claim 5 A method for preparing a tablet containing Acanthopanax sessiliflorus and

vitamin, including: (a) extracting the stem, leaf, fruit or root of Acanthopanax

sessiliflorus using water or organic solvent; (b) filtering, concentrating and

then drying the resultant extract; (c) grinding the resultant concentrated and

dried extract to prepare Acanthopanax sessiliflorus extract powder; (d) mixing

the resultant Acanthopanax sessiliflorus extract powder with vitamin C,

vitamin B-i, vitamin B₂, vitamin Be, a sugar and an additive; and (e) preparing

the resultant mixture into a tablet.

Claim 6

The method of Claim 5, the mixing in (d) is performed by mixing 0.1 to 5.0

wt% of Acanthopanax sessiliflorus extract powder with 0.1 to 5.0 wt% of

vitamin C, 0.001 to 0.01 wt% of vitamin Bi, 0.001 to 0.01 wt% of vitamin B₂,

0.001 to 0.01 wt% of vitamin B₆, 65.0 to 95.0 wt% of a sugar and 4.0 to 25.0

wt% of an additive, based on the total weight.

Claim 7

The method of Claim 5, the sugar in (d) is one or more selected from a group consisting of lactose, glucose, xylitol, fructose, isomalt, sucralose, cellulose and erythritol.

Claim 8

The method of Claim 5, the additive in (d) is one or more selected from a group consisting of enzymatically modified stevioside, magnesium stearate, organic acid calcium salt produced by fermentation, citric acid, folic acid, strawberry powder flavor, araliaceous flavor, strawberry flavor, yogurt flavor and whey calcium.