WO2010004416A3 - Method and relative apparatus for carrying out diagnostic analyses - Google Patents

Method and relative apparatus for carrying out diagnostic analyses Download PDF

Info

Publication number
WO2010004416A3
WO2010004416A3 PCT/IB2009/006201 IB2009006201W WO2010004416A3 WO 2010004416 A3 WO2010004416 A3 WO 2010004416A3 IB 2009006201 W IB2009006201 W IB 2009006201W WO 2010004416 A3 WO2010004416 A3 WO 2010004416A3
Authority
WO
WIPO (PCT)
Prior art keywords
biological sample
reaction
carrying
diagnostic analyses
kinetics
Prior art date
Application number
PCT/IB2009/006201
Other languages
French (fr)
Other versions
WO2010004416A2 (en
Inventor
Paolo Galiano
Giovanni Di Cola
Francesco Frappa
Original Assignee
Alifax Holding Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alifax Holding Spa filed Critical Alifax Holding Spa
Publication of WO2010004416A2 publication Critical patent/WO2010004416A2/en
Publication of WO2010004416A3 publication Critical patent/WO2010004416A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction

Abstract

Method for diagnostic analyses of a biological sample, comprising: - a step of preparing a mixture of a biological sample and one or more reactive agents, - a step of reaction of the antigen-antibody type, wherein the one or more reactive agents react in the mixture with one or more components of the biological sample according to a reaction kinetics. The method also comprises a step of measuring the initial speed at which the reaction occurs, and a step of comparing at least part of the reaction kinetics with standard kinetics having a known concentration, corresponding to a reaction of the same type as that to which the biological sample is subjected, so as verify if the initial concentration of antigen or antibody is greater than the concentration of the reference standard, in order to obtain an indication as to whether the biological sample is affected or not by the prozone effect.
PCT/IB2009/006201 2008-07-08 2009-07-07 Method and relative apparatus for carrying out diagnostic analyses WO2010004416A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITUD2008A000162 2008-07-08
IT000162A ITUD20080162A1 (en) 2008-07-08 2008-07-08 PROCEDURE AND RELATIVE EQUIPMENT FOR THE EXECUTION OF DIAGNOSTIC ANALYSIS

Publications (2)

Publication Number Publication Date
WO2010004416A2 WO2010004416A2 (en) 2010-01-14
WO2010004416A3 true WO2010004416A3 (en) 2010-04-15

Family

ID=40467056

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/006201 WO2010004416A2 (en) 2008-07-08 2009-07-07 Method and relative apparatus for carrying out diagnostic analyses

Country Status (2)

Country Link
IT (1) ITUD20080162A1 (en)
WO (1) WO2010004416A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2790019A1 (en) 2013-04-10 2014-10-15 Siemens Healthcare Diagnostics Products GmbH High dose hook detection
KR102593221B1 (en) * 2017-09-08 2023-10-24 알프레사 파마 가부시키가이샤 Analysis equipment and analysis methods
CN114113073A (en) * 2020-08-28 2022-03-01 深圳市帝迈生物技术有限公司 Method for judging generation of hook effect, immunoassay method and device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998025143A1 (en) * 1996-12-03 1998-06-11 Erkki Soini Biospecific, two photon excitation, fluorescence detection and device
US6284472B1 (en) * 1998-10-05 2001-09-04 Dade Behring Inc. Method for extending the range of an immunoassay
EP1845373A1 (en) * 2006-04-13 2007-10-17 Olympus Life and Material Science Europa GmbH An immunoassay method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998025143A1 (en) * 1996-12-03 1998-06-11 Erkki Soini Biospecific, two photon excitation, fluorescence detection and device
US6284472B1 (en) * 1998-10-05 2001-09-04 Dade Behring Inc. Method for extending the range of an immunoassay
EP1845373A1 (en) * 2006-04-13 2007-10-17 Olympus Life and Material Science Europa GmbH An immunoassay method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PAPIK K ET AL: "AUTOMATED PROZONE EFFECT DETECTION IN FERRITIN HOMOGENEOUS IMMUNOASSAYS USING NEURAL NETWORK CLASSIFIERS", CLINICAL CHEMISTRY AND LABORATORY MEDICINE, WALTER DE GRUYTER UND CO, vol. 37, no. 4, 1 April 1999 (1999-04-01), pages 471 - 476, XP001027770, ISSN: 1434-6621 *

Also Published As

Publication number Publication date
WO2010004416A2 (en) 2010-01-14
ITUD20080162A1 (en) 2010-01-09

Similar Documents

Publication Publication Date Title
WO2006126008A3 (en) Improved immunoassay methods
WO2005103698A3 (en) Methods and antibodies for nitrofuran detection
WO2007024735A3 (en) Method and antibodies for detecting nitrofuran
NZ609824A (en) Immunochromatography devices, methods and kits
WO2010065568A3 (en) METHODS AND ASSAYS FOR MEASURING p95 AND/OR p95 IN A SAMPLE AND ANTIBODIES SPECIFIC FOR p95
NZ602056A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2007103859A3 (en) Methods, products, and kits for identifying an analyte in a sample
WO2008007242A3 (en) Increased specificity of analyte detection by measurement of bound and unbound labels
DE602006021056D1 (en) PARAMETRIC CALIBRATION PROCEDURE
WO2009117510A3 (en) Multi-wavelength analyses of sol-particle specific binding assays
WO2010049672A3 (en) Methods and products for measuring free immunoglobulin light chain molecules
TW200741203A (en) Detection of a target antigen irrespective of the presence or absence of a corresponding therapeutic antibody
WO2003043487A3 (en) Method of using a non-antibody protein to detect and measure an analyte
WO2007040559A3 (en) Electrochemiluminescent assay
WO2006083367A3 (en) Immunoassay employing two-step internal calibration reaction
WO2008060394A3 (en) Methods and assays for detecting gp73-specific autoantibodies
WO2006132797A3 (en) Preparation of small liquid samples for automated analysis
MX2009006205A (en) Multiple analyte immunoassay.
WO2010051544A3 (en) Rapid homogeneous diagnostic testing platform based on lanthanide fluorescent resonance energy transfer
WO2013068572A3 (en) Blood sample assay method
WO2008155820A1 (en) Method of specifying error and analyzer
WO2006092729A3 (en) Novel biomarkers for diagnosis and/or prognosis or prognosis of neoplasias in animals
WO2014018278A3 (en) Multisignal reagents for labeling analytes
WO2007063326A3 (en) Assay device and method
WO2008124091A3 (en) Compositions and methods of detection

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09785998

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 09785998

Country of ref document: EP

Kind code of ref document: A2