WO2010000577A2 - Utilisation de honeybush ou d'extraits de honeybush pour la peau et les cheveux - Google Patents

Utilisation de honeybush ou d'extraits de honeybush pour la peau et les cheveux Download PDF

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Publication number
WO2010000577A2
WO2010000577A2 PCT/EP2009/057113 EP2009057113W WO2010000577A2 WO 2010000577 A2 WO2010000577 A2 WO 2010000577A2 EP 2009057113 W EP2009057113 W EP 2009057113W WO 2010000577 A2 WO2010000577 A2 WO 2010000577A2
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WO
WIPO (PCT)
Prior art keywords
skin
accordance
hair
product
honeybush
Prior art date
Application number
PCT/EP2009/057113
Other languages
English (en)
Other versions
WO2010000577A3 (fr
Inventor
Olivier Yves Roger
Vanessa Crespy
Original Assignee
Nestec S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec S.A. filed Critical Nestec S.A.
Publication of WO2010000577A2 publication Critical patent/WO2010000577A2/fr
Publication of WO2010000577A3 publication Critical patent/WO2010000577A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration

Definitions

  • the present invention relates to the use of honeybush or honeybush extract for improving skin or hair health by preventing, alleviating or treating skin or hair disorders or damages such as is effected by inflammatory reactions, environmental factors, ageing or cancer.
  • the present invention relates to the use of honeybush or honeybush extracts to improve UV protection or skin glow or reduce skin wrinkles or skin inflammation.
  • the most prominent epithelial tissue in living beings is the skin, which represents the largest organ in the organism.
  • the system of skin integument which comprises the epidermis, dermis and the stratum corneum, correlates with those of internal organs and concurrently interacts with the surroundings. Being the interface between the environment and organism itself, the skin is heavily influenced by external factors and also variable parameters of the organism's inner system.
  • the skin's regulative mechanisms need, therefore, always be active to induce systemic changes necessary to maintain normal pathological events concerning skin integument morphology and activities.
  • the cutaneous barrier is exposed daily to chemicals, xenobiotic and particles composing urban pollution.
  • atmospheric pollutants likely to exert noxious effects on the skin and the hair, three main categories can be distinguished. They are essentially gas, heavy metals, and particles which are the residues of combustion on which are adsorbed many organic compounds. The gases contribute more particularly to the formation of an environment "pro-oxidant" to which the most external surface tissues are directly exposed.
  • the oxidation and the degradation of the lipids of the stratum corneum can deteriorate the function barrier of the stratum corneum.
  • the disturbance of the external lipids and the architecture of proteins are factors starting in many dermatoses (psoriasis, atopic dermatitis, irritating dermatitis).
  • a significant oxidative attack on the level of the surface layers of the stratum can initiate subjacent localised inflammatory processes.
  • This deterioration of the cutaneous barrier can be in particular translated for a subject by feelings of cutaneous discomfort, phenomena sensory and/or the demonstration of undesirable cutaneous signs, even painful such as irritations.
  • the above mentioned signs of discomfort can be moreover associated with undesirable cutaneous signs, such as rednesses, irritations, scabs, erythemas inflammatory, oedemas and/or buttons.
  • EP 0 761 214 discloses singlet oxygen quenchers comprising aniline derivatives and difurfuryl amine derivatives, which are reported to reduce the oxidative stress to the skin.
  • an object of the present invention is to provide compositions that may be used over a long period of time by humans or pets, and susceptible to be provided in the form of a nutritional supplement, a food or petfood composition or a beverage.
  • Honeybush is a wild South African plant that grows in a specific area of the south-western part of South Africa, and that is commonly used by local populations to prepare infusion in the same manner as tea.
  • the scientific names of Honeybush species - thus called since its flowers have the smell of honey - that are most commonly consumed are Cyclopia intermedia, C. Subternata, C. Genistoides, C. Maculata.
  • the present invention relates to the use of an orally administrable composition comprising Honeybush or an extract thereof for the preparation of a product to improve skin or hair health, treat, alleviate and/or prevent skin or hair disorders.
  • the skin disorders or damages that can be treated, alleviated or prevented according to the present invention can for example be selected from the group consisting of skin inflammation, such as UV or chemical-induced skin inflammation, reactive or dry skin, psoriasis, vitiligo, acne, ageing, UV protection, photo ageing, wrinkles. It can also provide beneficial effects on skin hydration, skin moisture or skin glow.
  • skin inflammation such as UV or chemical-induced skin inflammation, reactive or dry skin, psoriasis, vitiligo, acne, ageing, UV protection, photo ageing, wrinkles. It can also provide beneficial effects on skin hydration, skin moisture or skin glow.
  • the hair (or coat) disorders or damages that can be treated or prevented are hair and coat gloss, hair density, color, oilness, ameliorating hair fiber diameter, sebum production, glossiness and preventing hair and coat loss.
  • composition according to the present invention is administered to a human or to an animal, for ameliorating antioxidant status or barrier function of the skin.
  • suitable extracts of Honeybush may be prepared by any means that are known in the art, e.g., by steam extraction, solvent extraction, distillation, pressing or grinding.
  • the extract is obtainable, in particular obtained, by extraction with a solvent from Cyclopia ssp. plant material, in particular by a water extraction or an alcohol/water extraction, for example by a ethanol/water extraction.
  • the Cyclopia extracts may also be obtainable, and are in particularly obtained by a method comprising the steps of: i) mixing and milling Cyclopia material in milk or a milk protein-containing liquid medium, ii) optionally separating insoluble material to obtain an aqueous suspension iii) optionally pasteurising the resulting suspension iv) optionally add synthetic or natural bioactive components during the processing v) and further optionally drying the suspension to obtain a powder.
  • This process has the advantage of being natural and cost effective enabling improved delivery of multi-nutrients in the form of a combination of stabilized water- and fat-soluble compounds in their natural compositions, free of organic solvent residues.
  • an extract of Cyclopia spp is used in the present invention it is preferred if at least 50wt.-%, preferably at least 70 wt.-% more preferably at least 95 wt.-% of the extract are water soluble. This has the advantage that the extract can easily be admixed with other water based foodstuffs before consumption.
  • honeybush tea is honeybush tea and also extracts that are commercially available, such as for example Honeybush from Afhplex or Honeybush from Rooibos Ltd.
  • the product comprising a composition comprising honeybush or an extract thereof according to the present invention may be for example a food product, a drink, a food supplement, a nutraceutical, a pet food product or a medicament.
  • the product may also further comprise a protein source, a carbohydrate source, a lipid source, a mineral source and/or a vitamin source.
  • a protein source a carbohydrate source
  • a lipid source a mineral source and/or a vitamin source.
  • proteins, carbohydrates, lipids, minerals and/or vitamins may have several advantages. These compounds generally contribute to the taste and mouthfeel of the final product. They also provide the body with nutrients that it may need urgently when it is affected by skin/hair disorders. They also allow formulating the product of the present invention as a complete nutritional formula, so that no additional nutrition is needed. This might be in particularly helpful for consumers that do not ingest sufficient amounts of food or that have trouble swallowing and that hence wish to ingest only small amounts of food.
  • the products used in the present invention are preferably intended for enteral application. Also a parenteral administration is possible. While the products are primarily intended to be used by humans, they may also be applied to animals, in particular companion animals, pets or livestock. Particularly preferred products are products selected from the group consisting of teas, iced teas, a foamed beverage, a confectionery product, a culinary product, a nutritional complete formula, a dairy product, a chilled or shelf stable beverage, a product for lactating mothers, a liquid drink, a soup, a dietary supplement, a meal replacement, a nutritional bar, a milk or a fermented milk product, a yoghurt, a milk based powder, an enteral nutrition product, an infant formula, an infant nutritional product, a puree, a cereal product or a fermented cereal based product, an ice-cream, candy, sweets, biscuits, cakes, a chocolate, a cappuccino, a coffee, a culinary product such as mayonnaise, tomato
  • Cyclopia spp or an extract thereof in the product will depend on several factors, such as the nature of the extract, the condition of the plant, the age, condition and size of the person or animal to be treated, the frequency, the product will be applied and/or the specific kind of skin/hair disorder or damage to be treated or prevented.
  • the present inventors have found that the effectiveness of Cyclopia spp or an extract thereof according to the present invention is generally dose dependant and follows a dose response curve. If generally mild skin/hair disorders or damages are to be prevented and the product will be used frequently, very small amounts of Cyclopia ssp or an extract thereof will be sufficient to achieve the desired effect. If a severe skin disorder is to be treated, larger amounts of Cyclopia spp or an extract thereof will be more appropriate, although also small amounts will produce an effect.
  • the product contains Cyclopia spp or an extract thereof in an amount in the range of about 0,1 g/l to 10 g/l, preferably in the range of 0,5 g/l to 3 g/l product. If the total amount of product cannot be measured in litres it is preferred if the product contains Cyclopia spp or an extract thereof in an amount in the range of about 0,1 g/kg to 10 g/kg, preferably in the range of 0,5 g/kg to 3 g/kg product.
  • the product contains Cyclopia spp or an extract thereof in a daily dose of 0,01 g-100g, preferably 0,25 g-10g.
  • the product may also comprises at least one kind of food grade micro-organism, in particular probiotics.
  • Food grade are all substances that are approved for human or animal consumption.
  • Probiotic means microbial cell preparations or components of microbial cells with a beneficial effect on the health or well-being of the host.
  • the probiotics may be selected from the group consisting of group consisting of Bifidobacterium, Lactobacillus, Streptococcus and Saccharomyces or mixtures thereof, in particular selected from the group consisting of Bifidobacterium longum, Bifidobacterium lactis, Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus johnsonii, Lactobacillus plantarum, Lactobacillus salivahus, Streptococcus faecium, Saccharomyces boulardii and Lactobacillus reuteri or mixtures thereof, preferably selected from the group consisting of Lactobacillus johnsonii NCC 533 (CNCM 1-1225), Bifidobacterium longum NCC 490 (CNCM 1-2170), Bifidobacterium longum NCC 2705 ⁇ CNCM 1-2618) , Bifidobacterium lactis
  • probiotics in a composition comprising Honeybush or an extract thereof may have several important effects. Consequently, the combination of probiotics with honeybush or an extract thereof can be expected to have a further positive effect on the treatment and prevention of skin/hair disorders or damages.
  • the product prepared for the use of the present invention may also contain at least one phytonutrient.
  • phytonutrient describes those plant compounds which have health- protecting qualities. For example antioxidant, immune boosting or other health promoting properties of active compounds in plants are typical effects of phytonutrients.
  • Phytonutrients include but are not limited to terpenes, carotenoids, limonoids, polyphenols, and phytosterols.
  • the carotenoids may be selected from the group consisting of carotenes and xanthophylls such as lycopene, carotene, phytofluene, phytoene, canthaxanthin, beta-cryptoxanthin, capsanthin, lutein, zeaxanthin, or those in the form of fatty acid esters, or mixtures thereof.
  • the polyphenols are preferably selected from the group consisting of flavones such as apigenin, luteolin or diosmetin, flavonols such as quercetin, myricetin, kaempferol, flavanones, anthocyanidins or isoflavones such as genistein, daidzein, or phenolic acids such as caffeic, ferulic acid or mixtures thereof.
  • flavones such as apigenin, luteolin or diosmetin
  • flavonols such as quercetin, myricetin, kaempferol, flavanones, anthocyanidins or isoflavones such as genistein, daidzein
  • phenolic acids such as caffeic, ferulic acid or mixtures thereof.
  • Preferred phytonutrients for the present invention are beta-carotene, lutein, and/or catechin.
  • the phytonutrients may be also provided in the form of a plant or plant extract.
  • Honeybush is added to the other ingredients as Honeybush extract powder.
  • “Honeybush” refers to Honeybush extract.
  • This Honeybush sweetening powder is obtained by the following preparation process, comprising the steps of, in order:
  • Powdered beverage composition comprising cereals, fruit powder and/or bits, and/or chocolate ingredients are prepared that incorporate an extract of Honeybush plant. They are formulated as follows (quantities are given in % of total weight of the composition):

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Public Health (AREA)
  • Veterinary Medicine (AREA)
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  • Gerontology & Geriatric Medicine (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

L'invention concerne l'utilisation de honeybush ou d'extraits de honeybush pour améliorer la santé de la peau ou des cheveux, consistant à prévenir, atténuer ou traiter les troubles ou dégâts qui affectent la peau ou les cheveux, par exemple sous l'effet des réactions inflammatoires, des facteurs environnementaux, de la sénescence ou du cancer. En particulier, l'invention concerne l'utilisation de honeybush ou d'extraits de honeybush pour améliorer la protection contre le rayonnement ultraviolet ou l'éclat de la peau ou bien pour réduire les rides ou l'inflammation de la peau.
PCT/EP2009/057113 2008-06-09 2009-06-09 Utilisation de honeybush ou d'extraits de honeybush pour la peau et les cheveux WO2010000577A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08157876 2008-06-09
EP08157876.7 2008-06-09

Publications (2)

Publication Number Publication Date
WO2010000577A2 true WO2010000577A2 (fr) 2010-01-07
WO2010000577A3 WO2010000577A3 (fr) 2010-06-24

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Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP2009/057116 WO2010000578A2 (fr) 2008-06-09 2009-06-09 Utilisation de honeybush ou d'extraits de honeybush avec des prébiotiques pour la peau et les cheveux
PCT/EP2009/057113 WO2010000577A2 (fr) 2008-06-09 2009-06-09 Utilisation de honeybush ou d'extraits de honeybush pour la peau et les cheveux

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/057116 WO2010000578A2 (fr) 2008-06-09 2009-06-09 Utilisation de honeybush ou d'extraits de honeybush avec des prébiotiques pour la peau et les cheveux

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013012197A3 (fr) * 2011-07-18 2013-04-11 한국한의학연구원 Composition pour prévenir ou atténuer les rides de la peau contenant de l'extrait de honeybush ou une liqueur fermentée de celui-ci en tant que principe actif

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0915315D0 (en) * 2009-09-03 2009-10-07 Univ Manchester Use of non-digestible oligosaccharides
FR3097436B1 (fr) * 2019-06-24 2023-10-13 Oreal Composition cosmétique comprenant une association d’au moins un oligosaccharide et/ou polysaccharide associé à un monosaccharide mannose

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003092413A1 (fr) * 2002-05-02 2003-11-13 Gardian Cipla (Pty) Ltd Complements alimentaires
FR2879446A1 (fr) * 2004-12-20 2006-06-23 Biolog Vegetale Yves Rocher Sa Composition comprenant un extrait de cyclopia sp

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200109559B (en) * 2000-09-14 2002-04-03 Benedict Technology Holdings P Preparation of tea-like beverages.
ZA200505219B (en) * 2005-06-28 2006-04-26 Cape Natural Tea Products Prop Process for making a beverage product

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003092413A1 (fr) * 2002-05-02 2003-11-13 Gardian Cipla (Pty) Ltd Complements alimentaires
FR2879446A1 (fr) * 2004-12-20 2006-06-23 Biolog Vegetale Yves Rocher Sa Composition comprenant un extrait de cyclopia sp

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "Intaba Honeybush" INTERNET CITATION, [Online] XP002336787 Retrieved from the Internet: URL:http://www.intabateas.com/honeybush-tea.shtml> [retrieved on 2005-07-19] *
MCKAY DIANE L ET AL: "A review of the bioactivity of South African herbal teas: Rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia)" PHYTOTHERAPY RESEARCH, vol. 21, no. 1, January 2007 (2007-01), pages 1-16, XP002500806 ISSN: 0951-418X *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013012197A3 (fr) * 2011-07-18 2013-04-11 한국한의학연구원 Composition pour prévenir ou atténuer les rides de la peau contenant de l'extrait de honeybush ou une liqueur fermentée de celui-ci en tant que principe actif
KR101295368B1 (ko) * 2011-07-18 2013-08-09 한국 한의학 연구원 허니부쉬 추출물 또는 이의 발효액을 유효성분으로 함유하는 피부 주름 개선용 조성물
US20140127189A1 (en) * 2011-07-18 2014-05-08 Korea Institute Of Oriental Medicine Composition for preventing or alleviating skin wrinkles containing honeybush extract or fermented honeybush as an active ingredient
EP2735304A4 (fr) * 2011-07-18 2015-05-13 Korea Inst Oriental Medicine Composition pour prévenir ou atténuer les rides de la peau contenant de l'extrait de honeybush ou une liqueur fermentée de celui-ci en tant que principe actif
US9439849B2 (en) 2011-07-18 2016-09-13 Korea Institute Of Oriental Medicine Composition for preventing or alleviating skin wrinkles containing honeybush extract or fermented honeybush as an active ingredient

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WO2010000578A3 (fr) 2010-06-24
WO2010000577A3 (fr) 2010-06-24
WO2010000578A2 (fr) 2010-01-07

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