WO2009158657A3 - Molecularly imprinted polymers for detecting microorganisms - Google Patents

Molecularly imprinted polymers for detecting microorganisms Download PDF

Info

Publication number
WO2009158657A3
WO2009158657A3 PCT/US2009/048928 US2009048928W WO2009158657A3 WO 2009158657 A3 WO2009158657 A3 WO 2009158657A3 US 2009048928 W US2009048928 W US 2009048928W WO 2009158657 A3 WO2009158657 A3 WO 2009158657A3
Authority
WO
WIPO (PCT)
Prior art keywords
microorganisms
molecularly imprinted
imprinted polymers
mips
methods
Prior art date
Application number
PCT/US2009/048928
Other languages
French (fr)
Other versions
WO2009158657A2 (en
Inventor
Robert L. Jones
Original Assignee
Columbia BioSystems, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia BioSystems, Inc. filed Critical Columbia BioSystems, Inc.
Priority to CN2009801296293A priority Critical patent/CN102105493A/en
Priority to EP09771188A priority patent/EP2303927A2/en
Publication of WO2009158657A2 publication Critical patent/WO2009158657A2/en
Publication of WO2009158657A3 publication Critical patent/WO2009158657A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus

Abstract

The invention described herein provides molecularly imprinted polymers (MIPs) that are capable of binding to a microorganism, and methods for detecting and/or identifying microorganisms utilizing Molecularly Imprinted Polymers (MIPs). The microorganisms of the invention include prokaryotes, eukaryotes, virus and prions. The methods of the invention comprise detecting all or part, including epitopes, of macromolecules associated with the microorganisms. The macromolecules of the invention include polysaccharides, proteins, glycoproteins, peptidoglycans, lipoproteins, peptides, polypeptides, and polynucleotides, associated with said microorganisms. The invention also provides for methods of diagnosing a subject infected with the microorganisms utilizing MIPs, in addition to diagnostic kits.
PCT/US2009/048928 2008-06-27 2009-06-26 Molecularly imprinted polymers for detecting microorganisms WO2009158657A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN2009801296293A CN102105493A (en) 2008-06-27 2009-06-26 Molecularly imprinted polymers for detecting microorganisms
EP09771188A EP2303927A2 (en) 2008-06-27 2009-06-26 Molecularly imprinted polymers for detecting microorganisms

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7635308P 2008-06-27 2008-06-27
US61/076,353 2008-06-27
US16945009P 2009-04-15 2009-04-15
US61/169,450 2009-04-15

Publications (2)

Publication Number Publication Date
WO2009158657A2 WO2009158657A2 (en) 2009-12-30
WO2009158657A3 true WO2009158657A3 (en) 2010-04-15

Family

ID=41445360

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/048928 WO2009158657A2 (en) 2008-06-27 2009-06-26 Molecularly imprinted polymers for detecting microorganisms

Country Status (4)

Country Link
US (1) US20090325147A1 (en)
EP (1) EP2303927A2 (en)
CN (1) CN102105493A (en)
WO (1) WO2009158657A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102317322B (en) * 2009-02-16 2014-01-01 依米戈有限公司 Customized molecularly imprinted polymer (mip) units
CA2801113A1 (en) * 2011-03-31 2012-10-04 Environmental Technology Solutions Polymers and task functionalized polymers for enhanced change detection
CN102887952A (en) * 2011-07-21 2013-01-23 广州瑞博奥生物科技有限公司 Monoclonal antibody against pbp2a derived from mrsa with dual binding activities
DE102012100396A1 (en) * 2012-01-18 2013-07-18 Frank Lützner Composition useful for detecting Mycobacterium avium subspecies paratuberculosis e.g. in human or animal, comprises molecularly imprinted polymer, which is held on solid support and capable of binding to Mycobacterium paratuberculosis
US9557250B2 (en) 2012-05-17 2017-01-31 The Board Of Trustees Of The Leland Stanford Junior University Devices and methods for separating particles
WO2014070727A1 (en) * 2012-10-29 2014-05-08 Freshair Sensor Corporation Molecularly imprinted polymer-based passive sensor
CN102924645B (en) * 2012-11-21 2014-03-26 安徽农业大学 Preparation method and application of molecularly imprinted polymer of penicillin antibiotics and intermediate of penicillin antibiotics
WO2014130793A1 (en) * 2013-02-21 2014-08-28 The Johns Hopkins University Epitope-polymer platform for detection of bacterial organisms
WO2015130529A2 (en) 2014-02-25 2015-09-03 Freshair Sensor Corporation Molecularly imprinted polymer sensors
CN104014320B (en) * 2014-06-19 2016-08-17 天津科技大学 A kind of aqueous metal organic frame molecular engram material of enriched with trace meta-tolyl-N-methylcarbamate (MTMC)
CN104931689A (en) * 2015-05-14 2015-09-23 桂林理工大学 Molecularly imprinted test paper strip and preparation method as well as application thereof
US10031119B1 (en) * 2015-11-05 2018-07-24 The United States Of America As Represented By The Secretary Of The Army Package and kit for explosive detection
CN105973827B (en) * 2016-05-17 2018-12-28 中山大学 Prepare the application in the molecular engram method and its Bacteria Detection of analog antibody
CN107132206B (en) * 2017-05-17 2020-02-07 武汉汉瑞隆德检测技术有限公司 Rapid detection method for virus activity
CN108722369B (en) * 2017-12-15 2020-12-25 南京大学 Universal convenient epitope imprinting method and application of obtained molecularly imprinted polymer
IT202000015145A1 (en) * 2020-06-24 2021-12-24 Moresense S R L METHOD FOR DETECTING A VIRUS IN A LIQUID MEDIUM, MOLECULAR SENSOR FOR ITS IMPLEMENTATION AND PROCEDURE FOR PREPARING THE MOLECULAR SENSOR.
CN112439393A (en) * 2020-11-17 2021-03-05 吉林化工学院 Preparation method and application of nucleic acid imprinted magnetic beads
CN113820367A (en) * 2021-07-27 2021-12-21 罗义 Electrochemical sensor for detecting new coronavirus in environment in real time and preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040121405A1 (en) * 2002-04-16 2004-06-24 Green Bernard S. Selective covalent-binding compounds having therapeutic diagnostic and analytical applications
US20070099189A1 (en) * 2003-05-30 2007-05-03 Instituto Nacional De Tecnica Aeroespacial "Esteban Terradas" Method and apparatus for detecting substances or analytes from the analysis of one or more samples
US20080071003A1 (en) * 2004-07-03 2008-03-20 University Of Dortmund Infu Method for Producing Molecularly Imprinted Polymers

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040121405A1 (en) * 2002-04-16 2004-06-24 Green Bernard S. Selective covalent-binding compounds having therapeutic diagnostic and analytical applications
US20070099189A1 (en) * 2003-05-30 2007-05-03 Instituto Nacional De Tecnica Aeroespacial "Esteban Terradas" Method and apparatus for detecting substances or analytes from the analysis of one or more samples
US20080071003A1 (en) * 2004-07-03 2008-03-20 University Of Dortmund Infu Method for Producing Molecularly Imprinted Polymers

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BARBARA WANDELT ET AL: "Fluorescent molecularly imprinted polymer studied by time-resolved fluorescence spectroscopy", POLYMER, vol. 43, no. 9, 2002, pages 2777 - 2785, XP004339244 *
MASAYO OGISO ET AL.: "DNA detection system using molecularly imprinted polymer as the gel matrix in electrophoresis.", BIOSENSORS AND BIOELECTRONICS., vol. 22, no. 9/10, 2007, pages 1974 - 1981, XP008141293 *
PARASKEVI PARMPI ET AL: "Biomimetic glucose recognition using molecularly imprinted polymer hydrogels", BIOMATERIALS, vol. 25, no. 10, 2004, pages 1969 - 1973, XP004485112 *

Also Published As

Publication number Publication date
US20090325147A1 (en) 2009-12-31
CN102105493A (en) 2011-06-22
WO2009158657A2 (en) 2009-12-30
EP2303927A2 (en) 2011-04-06

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