WO2009154358A3 - Diagnostic device having a microchannel - Google Patents

Diagnostic device having a microchannel Download PDF

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Publication number
WO2009154358A3
WO2009154358A3 PCT/KR2009/002753 KR2009002753W WO2009154358A3 WO 2009154358 A3 WO2009154358 A3 WO 2009154358A3 KR 2009002753 W KR2009002753 W KR 2009002753W WO 2009154358 A3 WO2009154358 A3 WO 2009154358A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
microchannel
area
reaction
diagnostic
Prior art date
Application number
PCT/KR2009/002753
Other languages
French (fr)
Korean (ko)
Other versions
WO2009154358A2 (en
Inventor
조영식
조병기
김정호
신상택
한승목
최기봉
박진구
임현우
조민수
Original Assignee
주식회사 에스디
국방과학연구소
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 에스디, 국방과학연구소 filed Critical 주식회사 에스디
Publication of WO2009154358A2 publication Critical patent/WO2009154358A2/en
Publication of WO2009154358A3 publication Critical patent/WO2009154358A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761—Hepatitis B
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The present invention concerns a diagnostic device having a microchannel which is able to improve the accuracy and efficiency of diagnosis. The diagnostic device having a microchannel comprises: a sample storage location for receiving a sample which has been taken through a sample-introduction port; a sample-reaction barrier wall for preventing back-diffusion of the sample; a reaction area having printed thereon a micro-pattern comprising a hydrophobic substance, and containing a conjugation body dissolved in and transported by the sample in a microchannel area; a diagnostic area in which is formed a test line to which is secured a binder body for binding in an antigen-antibody reaction with the conjugation body and/or an analysis substance within the sample in the microchannel area; and a waste-substances zone where the reaction solution and a wash solution finally collect after the reaction in the diagnostic area has finished.
PCT/KR2009/002753 2008-06-20 2009-05-25 Diagnostic device having a microchannel WO2009154358A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0058451 2008-06-20
KR1020080058451A KR20090132267A (en) 2008-06-20 2008-06-20 Diagnostic devices having micro channel

Publications (2)

Publication Number Publication Date
WO2009154358A2 WO2009154358A2 (en) 2009-12-23
WO2009154358A3 true WO2009154358A3 (en) 2010-03-04

Family

ID=41434525

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/002753 WO2009154358A2 (en) 2008-06-20 2009-05-25 Diagnostic device having a microchannel

Country Status (2)

Country Link
KR (1) KR20090132267A (en)
WO (1) WO2009154358A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040013731A (en) * 2002-08-08 2004-02-14 한국전자통신연구원 Microfluidic devices for the controlled movements of solution
KR20080027392A (en) * 2005-07-14 2008-03-26 나노디텍 코포레이션 Microfluidic devices and methods of preparing and using the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040013731A (en) * 2002-08-08 2004-02-14 한국전자통신연구원 Microfluidic devices for the controlled movements of solution
KR20080027392A (en) * 2005-07-14 2008-03-26 나노디텍 코포레이션 Microfluidic devices and methods of preparing and using the same

Also Published As

Publication number Publication date
KR20090132267A (en) 2009-12-30
WO2009154358A2 (en) 2009-12-23

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