WO2009144272A1 - Reservoir filling device - Google Patents
Reservoir filling device Download PDFInfo
- Publication number
- WO2009144272A1 WO2009144272A1 PCT/EP2009/056533 EP2009056533W WO2009144272A1 WO 2009144272 A1 WO2009144272 A1 WO 2009144272A1 EP 2009056533 W EP2009056533 W EP 2009056533W WO 2009144272 A1 WO2009144272 A1 WO 2009144272A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cartridge
- housing
- filling device
- venting
- reservoir
- Prior art date
Links
- 238000013022 venting Methods 0.000 claims abstract description 38
- 239000007788 liquid Substances 0.000 claims abstract description 18
- 239000012528 membrane Substances 0.000 abstract description 11
- 239000011521 glass Substances 0.000 abstract description 3
- 230000000149 penetrating effect Effects 0.000 description 9
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 241001631457 Cannula Species 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- 238000005429 filling process Methods 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000003708 ampul Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000012858 resilient material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2013—Piercing means having two piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2017—Piercing means having three or more piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2072—Venting means for internal venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
- A61J1/2075—Venting means for external venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2079—Filtering means
- A61J1/2082—Filtering means for gas filtration
Definitions
- the invention relates to a filling device for a reservoir which reservoir is to be filled from a cartridge such as cartridges having rigid walls e.g. made of glass and provided with a membrane which can be penetrated by a needle for protection of the entrance.
- a cartridge such as cartridges having rigid walls e.g. made of glass and provided with a membrane which can be penetrated by a needle for protection of the entrance.
- a problem which arises when manufacturing such filling devices is how to place the venting channel in order not to hamper the filling process or to contaminate the filling liquid which will normally be some kind of medication.
- US 4.296.786 discloses a transfer device for use in mixing substances in different containers which containers each are closed by a stopper of resilient material having a puncturable diaphragm.
- the transfer device consists of a central body portion and a pair of aligned spikes or cannulas projecting from opposite sides of this central body portion. This device is not provided with a venting needle moving independently of the filling needle, and therefore the joined spikes or cannulas according to this document have a relatively large diameter.
- the object of the invention is to provide a filling device which is easy to handle for the user, simple and non-expensive to manufacture and where the risk of breaking the venting needle during the filling process has been eliminated.
- the invention concerns a filling device which comprising - a housing comprising - a first position means adapted to receive a reservoir for receiving liquid,
- a second position means adapted to receive a cartridge containing a liquid
- venting unit providing access of gas to the cartridge during emptying of the cartridge
- at least a part of the venting unit is placed off the rotational centre (r c ) of the housing and is attached to a part.
- the invention is characterized in that this part can rotate relative to the housing and relative to the unit providing a flow path.
- the unit providing the flow path between the reservoir and the cartridge when they are at their positions comprises a needle having two pointy ends.
- the needle can be made of any kind of material which can penetrate the membranes protecting the access to respectively the cartridge and the reservoir, and the needle could be blunt at one end and pointed at the other end.
- the unit providing the flow path is placed along the rotational centre of the housing.
- the unit is fastened unreleasably to or is a part of a wall in the housing which wall separates the first position means adapted to receive the reservoir from the second position means adapted to receive the cartridge.
- the part which can rotate relative to the housing is formed as a circular plate which periphery is in proximity of or in slidable contact with walls of the housing.
- the circular plate can move in a track formed in the walls of the housing.
- the formation of a "track” prevents the circular plate from moving in a direction parallel to the rotational axis r c of the housing.
- the periphery of the circular plate is provided with a track formed along the periphery which track corresponds to one or more protruding part(s) of the housing.
- the circular plate can be provided with a friction layer which friction layer prevents that the cartridge moves in relation to the cartridge i.e. when the cartridge is pushed into the fitted second position means of the filling device housing and the venting unit has penetrated to the inner room of the cartridge then the friction layer will reduce the risk of any displacement of the cartridge relative to the rotary part.
- the venting unit comprises a venting needle which venting needle provides access from outside the cartridge to the inner room of the cartridge.
- the venting unit (5) can further comprise a venting valve (5b) which venting valve (5b) provides a one-way passage of clean gas into a room wherefrom the venting needle (5a) is provided with clean gas.
- "Clean gas” is considered to be gas of a quality as defined as necessary by the user or by the manufacturer of the device. It can be sterile gas but might be gas of a more inferior quality. Normally the gas will be atmospheric air.
- the venting needle is attached to the rotary part providing a flow path for clean gas from one side of the rotary part to the other and the venting valve can be attached to the open end of the venting needle pointing away from the cartridge.
- the venting valve can be attached to a wall of the housing proving access of clean gas from outside wall of the housing to the inside of the wall of the housing.
- the invention also relates to a kit combining a cartridge filling device according to any of the claims 1 -1 1 and a cartridge containing liquid which filling device can be either for single use and thereby permanently joined to the cartridge or for multiple use and thereby can be connected and disconnected to the cartridge.
- FIG. 1 shows a cut-through view of a filling device housing where a reservoir to be filled is half-way in position and a cartridge containing liquid is also half-way in position;
- Fig. 2 shows a cut-through view of a filling device housing where the venting valve is placed away from the venting needle.
- the embodiment of the reservoir filling device of fig. 1 is shown in a state where liquid cannot be transferred from the liquid containing cartridge 3 to the reservoir.
- the embodiment of the filling device comprises a housing 1 having cylindrical outer walls and a separating wall 8 dividing the housing into two positions, a first position for the reservoir 2 to be filled and a second position for the cartridge 3 to be emptied.
- Each position is either provided by the walls of the housing 1 thereby providing a close fit for the device to be placed there or is provided with guiding means assuring a well-defined final position of the device to be placed.
- both or one of the positions only comprise a central portion in form of the separating wall 8 having no outer walls.
- the positions including the guiding means are referred to as position means.
- the embodiment of the filling device further comprises a filling needle 4 which filing needle 4 provides a flow path for liquid flowing from the cartridge 3 to the reservoir 2.
- Both the cartridge 3 and the reservoir are in the embodiments of fig. 1 each provided with a membrane 6 and 10 which have to be penetrated by the filling needle 4 in order to create a flow path between the two units.
- the filling needle 4 is unreleasably attached to the separating walls 8 and kept in a stationary position relative to the housing 1 along the central axis of the housing 1 .
- the filling device is also provided with a rotary part 7 which according to this embodiment is formed as a turntable provided with a folding at the periphery.
- the folding provides a contact surface which can slide along the inner surface of the housing 1 wall.
- the rotary part 7 can rotate around the filling needle 4 which according to this embodiment is stationary relative to the housing 1 .
- the rotary part 7 is prevented from moving in the longitudinal direction by one or more protruding parts 12 preventing the rotary part 7 from moving towards the cartridge and the separating wall 8 preventing the rotary part 7 from moving towards the reservoir 2.
- Gas can pass from one side of the rotary part to the other through the venting needle 5 which according to this embodiment is constructed of a penetrating member 5a and a valve member 5b which two parts are joined.
- the penetrating member 5a is unreleasably attached to the rotary part 7 and provides a flow path for gas through the rotary part 7 and into the clean inner room 1 1 of the cartridge 3.
- the penetrating member 5a will normally be provided with a pointed end towards the cartridge in order for it to be able to cut through the membrane layer 6 protecting the entrance of the cartridge 3.
- the venting valve 5b is attached to the open end of the penetrating member 5a turned towards the reservoir 2 and the valve 5b allows for gas/air to pass from the room between the rotary part 7 and the separating wall 8 into the inner room 1 1 of the cartridge 3 when the penetrating member 5a has penetrated the membrane 6 and been inserted into this room.
- the valve 5b prevents micro organisms from accessing the clean inner room 1 1 of the cartridge 3.
- the rotary part 7 is according to this embodiment provided with one or more friction layers 9 on the side turned toward the cartridge 3.
- the friction layers 9 correspond to contact surfaces 13 on the cartridge 3 and when the friction layers 9 and the contact surfaces make contact the two units are "locked" relative to each other and move together.
- Fig. 1 also shows the reservoir 2 when this is pushed half-way into the position of the housing 1 , in this half-way position the filling needle 4 does not penetrate the septum or membrane 10 which is protecting the entrance of the reservoir 2.
- the reservoir 2 according to this embodiment is also provided with an illustrative piston with which liquid has been pushed out of the reservoir 2 during use and emptying of the reservoir 2.
- Fig. 2 shows another embodiment of a filling device according to the present invention.
- the penetrating member 5a and the venting valve 5b are separated from each other.
- the venting valve 5a transfers gas or air from the outside of the housing 1 into the clean room 1 1 between the rotary part 7 and the separating wall 8.
- the rotary part 7 must provide an airtight seal against the walls of the housing 1 .
- the penetrating member 5a has a blunt end turned toward the reservoir 2 and a pointed end turned toward the membrane of the cartridge 3.
- the penetrating member 5a When the cartridge 3 is pushed into position the penetrating member 5a will penetrate the membrane 6 and provide a flow path for clean gas/air between the clean room 1 1 formed between the rotary part 7 and the separating wall 8 and the inner clean room 1 1 of the cartridge 3. Gas will flow through this flow path when the pressure is reduced in the reservoir 2 as the piston 14 is pulled back.
- the filling needle 4 is provided with two pointed ends respectively penetrating the membrane 6 of the cartridge 3 and the membrane 10 of the reservoir 2 when these two devices are pushed into each their position.
- the housing 1 of the filling device according to the present invention need not be cylindrical or have a round profile but it should be able to provide a close fit between the rotary part 7 and the inner surface of the housing 1 especially according to the embodiment of fig. 2 where it is necessary to have clean atmosphere in the room between the rotary part 7 and the separating walls 8. If the inner surface of the housing at this position is not round it could be provided with a round track e.g. formed in a protruding part of the inner surface of the walls of the housing 1 .
- the liquid contained in the cartridge will often be a kind of medication which advantageously can be continuously administrated to a patient.
- This medication could e.g. be insulin which can be continuously administered to patients with diabetes.
- the cartridge 3 could be a glass ampoule containing an apportioned amount of insulin.
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Filling Or Discharging Of Gas Storage Vessels (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/994,234 US20110168294A1 (en) | 2008-05-30 | 2009-05-28 | Reservoir filling device |
MX2010013084A MX2010013084A (en) | 2008-05-30 | 2009-05-28 | Reservoir filling device. |
CN2009801244405A CN102202636A (en) | 2008-05-30 | 2009-05-28 | Reservoir filling device |
EP20090753927 EP2303220A1 (en) | 2008-05-30 | 2009-05-28 | Reservoir filling device |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5758008P | 2008-05-30 | 2008-05-30 | |
DKPA200800737 | 2008-05-30 | ||
DKPA200800737 | 2008-05-30 | ||
US61/057,580 | 2008-05-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009144272A1 true WO2009144272A1 (en) | 2009-12-03 |
Family
ID=40194608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2009/056533 WO2009144272A1 (en) | 2008-05-30 | 2009-05-28 | Reservoir filling device |
Country Status (5)
Country | Link |
---|---|
US (1) | US20110168294A1 (en) |
EP (1) | EP2303220A1 (en) |
CN (1) | CN102202636A (en) |
MX (1) | MX2010013084A (en) |
WO (1) | WO2009144272A1 (en) |
Cited By (26)
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US7985199B2 (en) | 2005-03-17 | 2011-07-26 | Unomedical A/S | Gateway system |
US8012126B2 (en) | 2006-10-31 | 2011-09-06 | Unomedical A/S | Infusion set |
US8062250B2 (en) | 2004-08-10 | 2011-11-22 | Unomedical A/S | Cannula device |
US8221355B2 (en) | 2004-03-26 | 2012-07-17 | Unomedical A/S | Injection device for infusion set |
US8303549B2 (en) | 2005-12-23 | 2012-11-06 | Unomedical A/S | Injection device |
US8430850B2 (en) | 2007-07-03 | 2013-04-30 | Unomedical A/S | Inserter having bistable equilibrium states |
US8439838B2 (en) | 2006-06-07 | 2013-05-14 | Unomedical A/S | Inserter for transcutaneous sensor |
US8486003B2 (en) | 2007-07-10 | 2013-07-16 | Unomedical A/S | Inserter having two springs |
US8562567B2 (en) | 2009-07-30 | 2013-10-22 | Unomedical A/S | Inserter device with horizontal moving part |
US8667996B2 (en) | 2009-05-04 | 2014-03-11 | Valeritas, Inc. | Fluid transfer device |
US8790311B2 (en) | 2006-06-09 | 2014-07-29 | Unomedical A/S | Mounting pad |
US8945057B2 (en) | 2006-08-02 | 2015-02-03 | Unomedical A/S | Cannula and delivery device |
US9186480B2 (en) | 2007-06-20 | 2015-11-17 | Unomedical A/S | Apparatus for making a catheter |
CN105107065A (en) * | 2010-06-09 | 2015-12-02 | 瓦莱里塔斯公司 | Fluid delivery device needle retraction mechanisms, cartridges and expandable hydraulic fluid seals |
US9211379B2 (en) | 2006-02-28 | 2015-12-15 | Unomedical A/S | Inserter for infusion part and infusion part provided with needle protector |
US9254373B2 (en) | 2008-12-22 | 2016-02-09 | Unomedical A/S | Medical device comprising adhesive pad |
US9415159B2 (en) | 2010-03-30 | 2016-08-16 | Unomedical A/S | Medical device |
US9440051B2 (en) | 2011-10-27 | 2016-09-13 | Unomedical A/S | Inserter for a multiplicity of subcutaneous parts |
US9533092B2 (en) | 2009-08-07 | 2017-01-03 | Unomedical A/S | Base part for a medication delivery device |
US9566384B2 (en) | 2008-02-20 | 2017-02-14 | Unomedical A/S | Insertion device with horizontally moving part |
US9724127B2 (en) | 2010-09-27 | 2017-08-08 | Unomedical A/S | Insertion system and insertion kit |
US10369277B2 (en) | 2005-09-12 | 2019-08-06 | Unomedical A/S | Invisible needle |
US10898643B2 (en) | 2008-02-13 | 2021-01-26 | Unomedical A/S | Sealing between a cannula part and a fluid path |
US11020526B2 (en) | 2010-10-04 | 2021-06-01 | Unomedical A/S | Sprinkler cannula |
US11110261B2 (en) | 2011-10-19 | 2021-09-07 | Unomedical A/S | Infusion tube system and method for manufacture |
US11197689B2 (en) | 2011-10-05 | 2021-12-14 | Unomedical A/S | Inserter for simultaneous insertion of multiple transcutaneous parts |
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US8764425B2 (en) | 2009-02-12 | 2014-07-01 | Picolife Technologies, Llc | Mold for making a membrane for use with a flow control system for a micropump |
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US8771229B2 (en) | 2011-12-01 | 2014-07-08 | Picolife Technologies, Llc | Cartridge system for delivery of medicament |
ES2587729T3 (en) * | 2012-03-01 | 2016-10-26 | Becton, Dickinson And Company Ltd. | Pressure compensating device and receptacle |
US10130759B2 (en) | 2012-03-09 | 2018-11-20 | Picolife Technologies, Llc | Multi-ported drug delivery device having multi-reservoir cartridge system |
US9883834B2 (en) | 2012-04-16 | 2018-02-06 | Farid Amirouche | Medication delivery device with multi-reservoir cartridge system and related methods of use |
US10245420B2 (en) | 2012-06-26 | 2019-04-02 | PicoLife Technologies | Medicament distribution systems and related methods of use |
WO2016153590A2 (en) * | 2015-01-22 | 2016-09-29 | The Regents Of The University Of California | Platelet rich plasma and bone marrow aspirate cell separation and removal methods and devices |
CN113227622B (en) * | 2018-11-26 | 2024-07-30 | 分配技术有限公司 | Inflatable elastic body and use thereof |
JP2022543652A (en) * | 2019-08-06 | 2022-10-13 | ビーディー キエストラ ベスローテン フェンノートシャップ | Disposable device for aeration of closed vessels and dispensing from closed vessels |
GB201918663D0 (en) | 2019-12-17 | 2020-01-29 | Oribiotech Ltd | A connector |
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US3783895A (en) * | 1971-05-04 | 1974-01-08 | Sherwood Medical Ind Inc | Universal parenteral fluid administration connector |
US4296786A (en) * | 1979-09-28 | 1981-10-27 | The West Company | Transfer device for use in mixing a primary solution and a secondary or additive substance |
WO1993011709A1 (en) * | 1991-12-09 | 1993-06-24 | Habley Medical Technology Corporation | Syringe-filling and medication mixing dispenser |
US6139534A (en) * | 2000-01-24 | 2000-10-31 | Bracco Diagnostics, Inc. | Vial access adapter |
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Also Published As
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CN102202636A (en) | 2011-09-28 |
MX2010013084A (en) | 2010-12-20 |
EP2303220A1 (en) | 2011-04-06 |
US20110168294A1 (en) | 2011-07-14 |
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