WO2009132503A1 - 一种治疗创口的装置 - Google Patents

一种治疗创口的装置 Download PDF

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Publication number
WO2009132503A1
WO2009132503A1 PCT/CN2009/000008 CN2009000008W WO2009132503A1 WO 2009132503 A1 WO2009132503 A1 WO 2009132503A1 CN 2009000008 W CN2009000008 W CN 2009000008W WO 2009132503 A1 WO2009132503 A1 WO 2009132503A1
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Prior art keywords
ozone
generator
wound
laser
ozone generator
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PCT/CN2009/000008
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English (en)
French (fr)
Inventor
姚广权
姚广智
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Yao Guangquan
Yao Guangzhi
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Publication of WO2009132503A1 publication Critical patent/WO2009132503A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0616—Skin treatment other than tanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light

Definitions

  • the present invention relates to the field of medical device technology, and more particularly to a technique for treating a wound. Background technique
  • the treatment of wounds is usually treated with drugs.
  • the drug treatment is easy to cause wound infection, and the treatment time is long. The curative effect is not very satisfactory.
  • some drugs may contain additives, such as penetration enhancers. Additives are too irritating and toxic, can interfere with wound healing and affect patient health.
  • the object of the present invention is to provide a device for treating wounds which is not easy to infect a wound, has a fast healing speed, has a short treatment time, and can effectively improve the therapeutic effect.
  • a device for treating a wound comprising a laser generator, characterized in that: the device further comprises an ozone generator, the ozone output of the ozone generator and the laser output of the laser generator acting on the wound.
  • the ozone output of the ozone generator interacts with the laser output of the laser generator through a treatment head to the wound.
  • the device further includes a controller, the controller is provided with a main computer control IC: The time when the generator and the ozone generator generate time display the control module of the control module, the laser generator and the ozone generator, and the connection detection module that detects the device.
  • the present invention has the following advantages over the prior art.
  • the present invention includes a laser generator and an ozone generator
  • the ozone output of the ozone generator cooperates with the laser output generated by the laser generator to act on the wound, and the ozone generator generates ozone and a small amount of nitric oxide, so at the wound
  • the photobiological effect of the laser is used to stimulate the activity of leukocyte galactose nucleotides.
  • laser irradiation promotes the formation and growth of new blood vessels, and makes the cell nucleus nucleic acid.
  • ozone acts as a strong oxidant. When it comes into contact with infected wounds, it produces a lot of oxygen free radicals and active oxygen. Oxygen free radicals are a very polar group.
  • NO in the blood vessel that fully enters the wound can regulate vascular tone, blood pressure, and cell-cell interaction, and regulate the blood vessel itself. Stability, inhibition of the occurrence and development of atherosclerosis, thus accelerate the healing of the wound. It can be seen that the use of semiconductor laser can improve the permeability of capillaries, accelerate the blood flow velocity, enhance the oxygen transport capacity of red blood cells, and more importantly, the ozone and nitric oxide generated by the ozone generator can fully enter the blood vessels of the wound. To achieve the purpose of cooperating with the laser on the lesion, nitric oxide in the blood vessels that fully enter the wound regulates the vascular tone.
  • Ozone is an attempt to kill the Pseudomonas, a particularly intractable bacteria, which is decomposed into oxygen with ozone.
  • An anoxic ulcer has a healing substance that provides a good outer ring for repair and regeneration of free-breathing normal human cells. Effectively improve the healing effect, which can speed up the healing of common wounds
  • the purpose of using the laser is mainly to enable the ozone generator and nitrogen monoxide generated by the ozone generator to fully enter the blood vessels of the wound, so that the nitric oxide in the blood vessel that fully enters the wound regulates the blood vessel tension, and the ozone is an attempt. Killing a particularly intractable bacteria, Pseudomonas, with the decomposition of ozone into oxygen, which causes the anoxic ulcer to heal, thus providing a good external environment for repair and regeneration of free-breathing normal cells.
  • the ozone and nitrogen monoxide generated by the ozone generator can not fully enter the blood vessels of the wound, so that the function of ozone and nitric oxide can not be achieved, and the healing speed of the wound can not be accelerated, and the curative effect is difficult. Improvement, only three of them, laser, ozone and nitric oxide work together on the lesion, can accelerate the healing rate of wounds, and effectively improve the treatment effect.
  • Figure 1 is a schematic view showing the structure of a device for treating a wound according to the present invention
  • FIG. 2 is a block diagram of a controller of the apparatus for treating a wound of the present invention. detailed description
  • the apparatus for treating a wound of the present invention comprises a laser generator 2, an ozone generator 4, an ozone output of the ozone generator 4 and a laser output of the laser generator 2 acting on a wound, wherein ozone generation occurs.
  • the device 4 can generate ozone and a small amount of nitrogen monoxide, and the nitrogen oxide is output together with the ozone.
  • the laser output of the laser generator 2 and the ozone output from the ozone generator 4 and a small amount of nitrogen monoxide can also pass through a treatment head 1 Acting on the wound, a vent hole 3 is provided in the lower portion of the treatment head 1, and ozone and a small amount of nitrogen monoxide are output from the vent hole 3.
  • the treatment head 1 is provided with a connecting line 6 and is electrically connected to a controller 5, and the controller 5 is provided with a main computer control IC: a laser generator and an ozone generator generating time display control module, a laser generator and ozone a control module for driving the generator power, a connection detection module for detecting the device, that is, the controller 5 is a laser 2 and an ozone generator 4 Raw drive power, control generation time and connection detection of the device.
  • the laser generator 2 inputs 3 V DC to generate a wavelength of 650-830 nm, wherein the output power is 5-90 mW, the spot diameter is 3-5 mm, and the irradiation distance is 0. 5-1. 0 cm.
  • the generated ozone and nitric oxide in the semiconductor laser Directly acts on the lesion area under irradiation, allowing ozone and nitric oxide to fully enter the blood vessels of the wound, so that nitric oxide in the blood vessels of the wound can fully regulate the vascular tone.
  • Ozone is an attempt to kill a particularly difficult bacteria. The bacteria, along with the decomposition of ozone into oxygen, make the hypoxic ulcer mouth healed, thus providing a good external environment for repair and regeneration of normal human cells that are free to breathe, effectively improving the therapeutic effect.
  • the present invention uses the laser beam emitted by the laser generator to irradiate the wound, so that the ozone and nitrogen monoxide generated by the ozone generator can fully enter the blood vessel of the wound, so that the three methods jointly act on the wound, thereby effectively improving the wound.
  • the therapeutic effect can accelerate the healing rate of common wounds by more than 1/4, and it is also effective for the treatment of diabetic lower extremity ulcers which are difficult to heal.

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  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

一种治疗创口的装置 技术领域
本发明涉及一种医疗器械技术领域， 具体地说是一种治疗创口的 装置的技术。 背景技术
创伤一般分为急性创伤和慢性创伤，急性创伤例如为烧伤和外科 创伤， 而慢性创伤为伤褥、 下肢溃疡和糖尿病溃疡。 创伤都会引起创 伤疼痛， 这种疼痛会剌激儿茶酚胺释放， 结果造成局部血管性收缩， 引起创伤部位供氧减少，这可能影响创伤口的愈合和对创伤感染的抵 抗力。现在治疗创伤，一般是用药物治疗，药物治疗易使创伤口感染， 而且治疗时间长， 疗效并不是很理想， 有时为了增大药物的渗透性， 有些药物会含有添加剂， 诸如渗透增强剂， 这些添加剂剌激性太强， 而且有毒性， 会妨碍创伤愈合， 并影响患者的健康。 在现有的技术当 中， 也有利用激光来治疗创口， 疗效不是很理想， 尤其是在加快创口 的愈合速度方面不是很理想， 因此如何提高疗效、加快创口的愈合速 度是常困扰着医学工作者的技术难题。 发明内容
本发明的目的是提供一种不易使创口感染， 创口的愈合速度快， 治疗时间短， 可有效提高疗效的治疗创口的装置。
本发明的目的通过以下技术方案来实现。
一种治疗创口的装置， 包括激光发生器， 其特征在于： 所述装置 还包括一臭氧发生器，臭氧发生器的臭氧输出与激光发生器的激光输 出共同作用于创口。
所述臭氧发生器的臭氧输出与激光发生器的激光输出通过一治 疗头共同作用于创口。
所述装置还包括一控制器， 控制器内设有主电脑控制 IC：、 激光 发生器和臭氧发生器产生时间的时间显示控制模块、激光发生器和臭 氧发生器的驱动电能的控制模块、 对装置进行检测的连线检测模块。
本发明与现有技术相比具有以下优点。
由于本发明包括有激光发生器和臭氧发生器，臭氧发生器的臭氧 输出与激光发生器产生的激光输出共同作用于创口，而且臭氧发生器 可产生臭氧和少量的一氧化氮，因此在创口处有激光和臭氧和一氧化 氮共同作用， 也就是说利用激光的光生物效应， 剌激白细胞半乳糖核 苷酸的活性， 同时激光照射促进了新生血管的形成及生长， 并使细胞 内核糖核酸及糖原的含量增加， 成纤维细胞增生， 肉芽组织生长， 导 致新生上皮组织再生， 改善毛细血管的透过度， 加速血流速度， 从而 使臭氧发生器产生的臭氧和一氧化氮能够充分进入创口的血管里，而 臭氧作为一种强氧化剂， 当其接触感染创面时， 会产生大量氧自由基 及活性氧，而氧自由基是一种极性很强的基团，为了达到自身的稳定， 必须夺取另外一稳定分子的一个电子，而位于创口表面的细菌就首当 其冲成为自由基攻击的对象， 使其细胞膜中不饱和脂肪酸结构改变， 引起细胞的损伤， 从而完成了消灭细菌的关键过程， 即杀死特别难处 理的细菌——假单胞菌，另外产生的活性氧使缺氧溃疡口得到了愈合 的物质，为可以自由呼吸的人体正常细胞提供了修复及再生的良好外 部环境， 促进了创面的愈合； 我们知道 NO是内皮细胞产生的血管舒 张因子， 当血清中的 NO减少， 会产生扩血管障碍， 使血管功能紊乱， 因此在激光的作用下使充分进入创口的血管里的 NO 可调节血管张 力、 血压及细胞间的相互作用， 调节血管的自身稳定性， 阻抑动脉粥 样硬化的发生与发展， 从而加速了伤口的愈合。 由此可见利用半导体 激光可改善毛细血管的透过度， 加速血流速度， 加强红细胞的运氧能 力，更重要的是可使臭氧发生器产生的臭氧和一氧化氮能够充分进入 创口的血管里， 达到与激光共同作用于病灶的目的， 其中充分进入创 口的血管里的一氧化氮调节血管张力，臭氧是企图杀死特别难处理的 细菌一假单胞菌， 随着臭氧的分解成氧， 使缺氧溃疡口得到了愈合的 物质，从而为自由呼吸的人体正常细胞提供修复及再生的良好外部环 境， 有效地提高了治疗效果， 这样可以使普通创口的愈合速度加快
1/4以上， 对于难以愈合的糖尿病下肢溃疡的治疗也有很好的疗效。 由此可见，利用激光的目的主要是使臭氧发生器产生的臭氧和一氧化 氮能够充分地进入创口的血管里，这样使充分进入创口的血管里的一 氧化氮调节血管张力，而臭氧是企图杀死特别难处理的细菌一假单胞 菌， 随着臭氧的分解成氧， 使缺氧溃疡口得到了愈合的物质， 从而为 自由呼吸的人体正常细胞提供修复及再生的良好外部环境，如果没有 激光的照射，则臭氧发生器产生的臭氧和一氧化氮不能充分地进入创 口的血管里， 从而发挥不了臭氧和一氧化氮的功能， 创口的愈合速度 也就加快不了， 疗效也就很难提高， 只有三者即激光、 臭氧和一氧化 氮共同作用于病灶， 才可以加快创口的愈合速度， 有效地提高治疗效 果。 附图说明
图 1为本发明治疗创口的装置结构示意图；
图 2为本发明治疗创口的装置之控制器方框图。 具体实施方式
下面结合附图对本发明治疗创口的装置作进一步详细描述。 如图 1、 图 2所示， 本发明治疗创口的装置， 包括激光发生器 2， 臭氧发生器 4， 臭氧发生器 4的臭氧输出与激光发生器 2的激光输出 共同作用于创口， 其中臭氧发生器 4可产生臭氧和少量的一氧化氮， 且一氧化氮与臭氧一起输出，激光发生器 2的激光输出与从臭氧发生 器 4输出的臭氧和少量的一氧化氮也可通过一治疗头 1作用于创口， 在治疗头 1 的下部设有排气孔 3， 臭氧和少量的一氧化氮从排气孔 3 输出。 治疗头 1设有连接线 6且与一控制器 5相电连接， 控制器 5内 设有主电脑控制 IC：、 激光发生器和臭氧发生器产生时间的时间显示 控制模块、激光发生器和臭氧发生器的驱动电能的控制模块、对装置 进行检测的连线检测模块，即控制器 5为激光器 2和臭氧发生器 4产 生驱动电能、 控制产生时间及对装置进行连线检测。
在控制器 5的控制下，激光发生器 2输入 3V直流电，产生 650-830 nm的波长， 其中输出功率为 5-90 mW, 光斑直径 3-5 mm, 照射距离 0. 5-1 . 0 cm, 持续式垂直照射病灶区； 臭氧电源输入 3V直流电， 产生 30KV 交变电压， 在沿面放电器上产生臭氧， 其中臭氧浓度为 0. 21mg/m 3 , 产生的臭氧和一氧化氮在半导体激光的照射下直接作用 于病灶区， 使臭氧和一氧化氮充分进入创口的血管里， 这样充分进入 创口的血管里的一氧化氮调节血管张力，臭氧是企图杀死特别难处理 的细菌一假单胞菌， 随着臭氧的分解成氧， 使缺氧溃疡口得到了愈合 的物质，从而为自由呼吸的人体正常细胞提供修复及再生的良好外部 环境， 有效地提高了治疗效果。
由上述可知， 本发明利用激光发生器发射的激光束照射创口， 使 臭氧发生器产生的臭氧和一氧化氮充分进入创口的血管里，这样通过 三种方法共同作用于创口， 从而有效地提高了治疗效果， 这样可以使 普通创口的愈合速度加快 1/4以上，对于难以愈合的糖尿病下肢溃疡 的治疗也有很好的疗效。

Claims

权利要求
1、 一种治疗创口的装置， 包括激光发生器， 其特征在于： 所述 装置还包括一臭氧发生器，臭氧发生器的臭氧输出与激光发生器的激 光输出共同作用于创口。
2、 根据权利要求 1所述的治疗创口的装置， 其特征在于： 所述 臭氧发生器的臭氧输出与激光发生器的激光输出通过一治疗头共同 作用于创口。
3、根据权利要求 1或 2所述的治疗创口的装置，其特征在于： 所 述装置还包括一控制器， 控制器内设有主电脑控制 IC：、 激光发生器 和臭氧发生器产生时间的时间显示控制模块、激光发生器和臭氧发生 器的驱动电能的控制模块、 对装置进行检测的连线检测模块。
PCT/CN2009/000008 2008-04-30 2009-01-05 一种治疗创口的装置 WO2009132503A1 (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018219621A1 (en) * 2017-05-31 2018-12-06 Termosalud, S.L. Device combining laser technology with ozone and its use in a method to treat fungal infections

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101979110A (zh) * 2010-11-02 2011-02-23 岑志勇 光子糖尿病治疗仪
CA2945724C (en) * 2013-10-24 2022-12-06 Bsn Medical Gmbh Immersion device
US10569097B2 (en) * 2015-07-28 2020-02-25 Photonmd, Inc. Systems and methods for phototherapeutic modulation of nitric oxide
CN106074137A (zh) * 2016-08-10 2016-11-09 武汉德仁科技开发有限公司 创面治疗修复仪

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156028A (en) * 1994-03-21 2000-12-05 Prescott; Marvin A. Method and apparatus for therapeutic laser treatment of wounds
CN2538375Y (zh) * 2002-04-10 2003-03-05 黎国柱 一种激光照射治疗仪
WO2004089469A1 (en) * 2003-02-14 2004-10-21 Advanced Medical Applications, Inc. Wound treatment method and device
WO2004098710A1 (en) * 2003-05-05 2004-11-18 Håkan Lagergren Ab Laser apparatus for heat treatment
CN2684814Y (zh) * 2004-02-20 2005-03-16 朱戈 一种臭氧创伤治疗仪

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156028A (en) * 1994-03-21 2000-12-05 Prescott; Marvin A. Method and apparatus for therapeutic laser treatment of wounds
CN2538375Y (zh) * 2002-04-10 2003-03-05 黎国柱 一种激光照射治疗仪
WO2004089469A1 (en) * 2003-02-14 2004-10-21 Advanced Medical Applications, Inc. Wound treatment method and device
WO2004098710A1 (en) * 2003-05-05 2004-11-18 Håkan Lagergren Ab Laser apparatus for heat treatment
CN2684814Y (zh) * 2004-02-20 2005-03-16 朱戈 一种臭氧创伤治疗仪

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018219621A1 (en) * 2017-05-31 2018-12-06 Termosalud, S.L. Device combining laser technology with ozone and its use in a method to treat fungal infections

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