WO2009130515A3 - Method and system for recording and promoting peripheral nerve regeneration - Google Patents
Method and system for recording and promoting peripheral nerve regeneration Download PDFInfo
- Publication number
- WO2009130515A3 WO2009130515A3 PCT/GR2009/000024 GR2009000024W WO2009130515A3 WO 2009130515 A3 WO2009130515 A3 WO 2009130515A3 GR 2009000024 W GR2009000024 W GR 2009000024W WO 2009130515 A3 WO2009130515 A3 WO 2009130515A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nerve
- stimulating
- recording
- electronic unit
- distal segment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A61N1/0556—Cuff electrodes
Abstract
Method and system for recording and promoting the regeneration of peripheral nerves after injury that comprise one stimulating electrode that is implanted at the proximal segment of the nerve, at least one recording electrode that is implanted at the distal segment of the nerve, an implantable electronic unit, an implantable device releasing agents for stimulating nerve regeneration, such as a micro-pump, and a computing unit that is preferably placed extracorporeally for the communication of data and transfer of power to the electronic unit. The electrical signals that are produced by the distal segment of the injured nerves after appropriate electrical excitation of the distal segment of said injured nerve are recorded at various time instances. The analysis of the recorded electric signals is used to assess the state and progress of the regenerating neuroaxons; this assessment is used for determining various control parameters. Said control parameters are used by the electronic unit so as to control the release of stimulating agents in such a way that treatment is effective while keeping the administration of stimulating agents at safe levels.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09734126A EP2307090A2 (en) | 2008-04-22 | 2009-04-15 | Method and system for recording and promoting peripheral nerve regeneration |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20080100282A GR1006568B (en) | 2008-04-22 | 2008-04-22 | Method and system for recording of, and aiding in, the regeneration of a peripheral nerve. |
GR20080100282 | 2008-04-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009130515A2 WO2009130515A2 (en) | 2009-10-29 |
WO2009130515A3 true WO2009130515A3 (en) | 2010-04-01 |
Family
ID=40585045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GR2009/000024 WO2009130515A2 (en) | 2008-04-22 | 2009-04-15 | Method and system for recording and promoting peripheral nerve regeneration |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2307090A2 (en) |
GR (1) | GR1006568B (en) |
WO (1) | WO2009130515A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11554265B2 (en) | 2011-05-13 | 2023-01-17 | Saluda Medical Pty Ltd | Method and apparatus for application of a neural stimulus |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10588524B2 (en) * | 2011-05-13 | 2020-03-17 | Saluda Medical Pty Ltd | Method and apparatus for measurement of neural response |
JP6243328B2 (en) | 2011-05-13 | 2017-12-06 | サルーダ・メディカル・ピーティーワイ・リミテッド | Method and apparatus for controlling neural stimulation |
US10568559B2 (en) | 2011-05-13 | 2020-02-25 | Saluda Medical Pty Ltd | Method and apparatus for measurement of neural response |
CN103648583B (en) | 2011-05-13 | 2016-01-20 | 萨鲁达医疗有限公司 | For measuring method and the instrument of nerves reaction-A |
US9974455B2 (en) | 2011-05-13 | 2018-05-22 | Saluda Medical Pty Ltd. | Method and apparatus for estimating neural recruitment |
US9155892B2 (en) | 2011-05-13 | 2015-10-13 | Saluda Medical Pty Limited | Method and apparatus for application of a neural stimulus |
DK2908904T3 (en) | 2012-11-06 | 2020-12-14 | Saluda Medical Pty Ltd | SYSTEM FOR CONTROLING THE ELECTRICAL CONDITION OF TISSUE |
WO2015070281A1 (en) | 2013-11-15 | 2015-05-21 | Saluda Medical Pty Ltd | Monitoring brain neural potentials |
AU2014353891B2 (en) | 2013-11-22 | 2020-02-06 | Saluda Medical Pty Ltd | Method and device for detecting a neural response in a neural measurement |
US10368762B2 (en) | 2014-05-05 | 2019-08-06 | Saluda Medical Pty Ltd. | Neural measurement |
DK3171929T3 (en) | 2014-07-25 | 2021-05-25 | Saluda Medical Pty Ltd | DOSAGE FOR NERVE STIMULATION |
US10597636B2 (en) | 2014-09-19 | 2020-03-24 | University Of Florida Research Foundation, Inc. | Electroactive polymeric scaffolds and method for delivering nerve growth factor to nerve tissue |
EP3215216A4 (en) | 2014-11-17 | 2018-08-22 | Saluda Medical Pty Ltd | Method and device for detecting a neural response in neural measurements |
AU2015362075B2 (en) | 2014-12-11 | 2021-03-11 | Saluda Medical Pty Ltd | Implantable electrode positioning |
EP4285985A3 (en) | 2014-12-11 | 2024-01-17 | Saluda Medical Pty Ltd | Method and device for feedback control of neural stimulation |
AU2016208972B2 (en) | 2015-01-19 | 2021-06-24 | Saluda Medical Pty Ltd | Method and device for neural implant communication |
US10894158B2 (en) | 2015-04-09 | 2021-01-19 | Saluda Medical Pty Ltd | Electrode to nerve distance estimation |
CA2983336A1 (en) | 2015-05-31 | 2016-12-08 | Saluda Medical Pty Ltd | Monitoring brain neural activity |
WO2016191807A1 (en) | 2015-05-31 | 2016-12-08 | Saluda Medical Pty Ltd | Brain neurostimulator electrode fitting |
CA2980482C (en) | 2015-06-01 | 2023-09-26 | Saluda Medical Pty Ltd | Motor fibre neuromodulation |
US11191966B2 (en) | 2016-04-05 | 2021-12-07 | Saluda Medical Pty Ltd | Feedback control of neuromodulation |
US11179091B2 (en) | 2016-06-24 | 2021-11-23 | Saluda Medical Pty Ltd | Neural stimulation for reduced artefact |
WO2018232145A1 (en) * | 2017-06-14 | 2018-12-20 | Wichita State University | Apparatus and method for neural regeneration |
AU2018354250A1 (en) | 2017-10-25 | 2020-06-11 | Epineuron Technologies Inc. | Systems and methods for delivering neuroregenerative therapy |
US10589089B2 (en) | 2017-10-25 | 2020-03-17 | Epineuron Technologies Inc. | Systems and methods for delivering neuroregenerative therapy |
EP3784338A4 (en) | 2018-04-27 | 2022-01-19 | Saluda Medical Pty Ltd | Neurostimulation of mixed nerves |
US11364381B2 (en) | 2019-10-01 | 2022-06-21 | Epineuron Technologies Inc. | Methods for delivering neuroregenerative therapy and reducing post-operative and chronic pain |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060089751A1 (en) * | 1997-01-27 | 2006-04-27 | Ewa Herbst | Electronic delivery systems and methods with feedback |
US20060194724A1 (en) * | 2005-02-25 | 2006-08-31 | Whitehurst Todd K | Methods and systems for nerve regeneration |
WO2006108262A2 (en) * | 2005-04-15 | 2006-10-19 | Lozano Andres M | Regulation of neurotrophins |
WO2008005843A2 (en) * | 2006-06-30 | 2008-01-10 | Cyberkinetics Neurotechnology Systems, Inc. | Nerve regeneration system and lead devices associated therewith |
-
2008
- 2008-04-22 GR GR20080100282A patent/GR1006568B/en not_active IP Right Cessation
-
2009
- 2009-04-15 WO PCT/GR2009/000024 patent/WO2009130515A2/en active Application Filing
- 2009-04-15 EP EP09734126A patent/EP2307090A2/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060089751A1 (en) * | 1997-01-27 | 2006-04-27 | Ewa Herbst | Electronic delivery systems and methods with feedback |
US20060194724A1 (en) * | 2005-02-25 | 2006-08-31 | Whitehurst Todd K | Methods and systems for nerve regeneration |
WO2006108262A2 (en) * | 2005-04-15 | 2006-10-19 | Lozano Andres M | Regulation of neurotrophins |
WO2008005843A2 (en) * | 2006-06-30 | 2008-01-10 | Cyberkinetics Neurotechnology Systems, Inc. | Nerve regeneration system and lead devices associated therewith |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11554265B2 (en) | 2011-05-13 | 2023-01-17 | Saluda Medical Pty Ltd | Method and apparatus for application of a neural stimulus |
Also Published As
Publication number | Publication date |
---|---|
GR1006568B (en) | 2009-10-13 |
EP2307090A2 (en) | 2011-04-13 |
WO2009130515A2 (en) | 2009-10-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2009130515A3 (en) | Method and system for recording and promoting peripheral nerve regeneration | |
WO2005002664A3 (en) | Methods and apparatus for effectuating a lasting change in a neural-function of a patient | |
WO2011112773A3 (en) | Modular stimulator for treatment of back pain, implantable rf ablation system and methods of use | |
ES2532140T3 (en) | Device for the prescription and controlled administration of transcranial stimulation treatments with direct current in humans | |
WO2011156439A3 (en) | Neural modulation devices and methods | |
ATE425698T1 (en) | DEVICE FOR INTRA-OPERATIVE MONITORING OF NERVES | |
WO2010002936A3 (en) | Systems, methods and devices for paired plasticity | |
JP2016064151A5 (en) | ||
RU2013101600A (en) | Incontinence Treatment | |
WO2006113801A3 (en) | Electrical stimulation device and method for therapeutic treatment and pain management | |
WO2007136694A3 (en) | Method and apparatus for stimulating a nerve of a patient | |
WO2009105473A3 (en) | Methods and devices for follow-up care and treatment of a pneumostoma | |
ATE429949T1 (en) | NEUROMUSCULAR STIMULATION | |
WO2008109812A3 (en) | External defibrillators, transcutaneous electrodes for same, and methods of use | |
MX2020011008A (en) | Implants using ultrasonic communication for modulating splenic nerve activity. | |
US11826572B2 (en) | Nerve block by electrical pulses at sub-threshold intensity | |
WO2016069687A3 (en) | Method and system for monitoring and treating a medical condition via posterior tibial nerve stimulation | |
WO2012064021A3 (en) | Knee-joint treatment apparatus using high frequency | |
WO2007115220A3 (en) | Hand-held electrical stimulation device | |
Reddy et al. | Miniaturized-electroneurostimulators and self-powered/rechargeable implanted devices for electrical-stimulation therapy | |
US20170281945A1 (en) | Nerve stimulation to promote neuroregeneration | |
EP2768580B1 (en) | Electrical stimulation device having multiple stimulation channels | |
CN107261321A (en) | Process and each portable electric stimulation apparatus using the agreement for setting up electro photoluminescence agreement | |
CN106573144A (en) | Depletion block to block nerve communication | |
AU2020300506A1 (en) | Neural block by super-threshold low frequency electrical stimulation |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 09734126 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2009734126 Country of ref document: EP |