GR1006568B - Method and system for recording of, and aiding in, the regeneration of a peripheral nerve. - Google Patents

Method and system for recording of, and aiding in, the regeneration of a peripheral nerve.

Info

Publication number
GR1006568B
GR1006568B GR20080100282A GR20080100282A GR1006568B GR 1006568 B GR1006568 B GR 1006568B GR 20080100282 A GR20080100282 A GR 20080100282A GR 20080100282 A GR20080100282 A GR 20080100282A GR 1006568 B GR1006568 B GR 1006568B
Authority
GR
Greece
Prior art keywords
regeneration
nerve
recording
electronic unit
aiding
Prior art date
Application number
GR20080100282A
Other languages
Greek (el)
Inventor
Αλεξανδρος Μπερης
Original Assignee
Αλεξανδρος Μπερης
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Αλεξανδρος Μπερης filed Critical Αλεξανδρος Μπερης
Priority to GR20080100282A priority Critical patent/GR1006568B/en
Priority to PCT/GR2009/000024 priority patent/WO2009130515A2/en
Priority to EP09734126A priority patent/EP2307090A2/en
Publication of GR1006568B publication Critical patent/GR1006568B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Prostheses (AREA)

Abstract

Method and system for the recording of, and aiding in, the regeneration of peripheral nerves after injury, which comprise a stimulation electrode which can be implanted in the central part of the nerve, at least one recording electrode which can beimplanted in the peripheral part of the nerve, an implantable electronic unit, an implantable device that releases regeneration-stimulating agents, such as a micro-pump, and a computational unit which is preferably positioned extra-corporeally for the transmission of data and energy to the electronic unit. The electric signals produced by the peripheral part of the injured nerve, after suitable electric stimulation of the central part thereof, are recorded on various time moments. The analysis of the recorded electric signals is used for the evaluation of the state and progress of the axons under regeneration, from which evaluation various control parameters are determined. The said parameters are used by the electronic unit in order to adjust the release of the stimulating agents so that the therapy is effective, maintaining at the same time the administration of agents at safe levels.
GR20080100282A 2008-04-22 2008-04-22 Method and system for recording of, and aiding in, the regeneration of a peripheral nerve. GR1006568B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (en) 2008-04-22 2008-04-22 Method and system for recording of, and aiding in, the regeneration of a peripheral nerve.
PCT/GR2009/000024 WO2009130515A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration
EP09734126A EP2307090A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (en) 2008-04-22 2008-04-22 Method and system for recording of, and aiding in, the regeneration of a peripheral nerve.

Publications (1)

Publication Number Publication Date
GR1006568B true GR1006568B (en) 2009-10-13

Family

ID=40585045

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20080100282A GR1006568B (en) 2008-04-22 2008-04-22 Method and system for recording of, and aiding in, the regeneration of a peripheral nerve.

Country Status (3)

Country Link
EP (1) EP2307090A2 (en)
GR (1) GR1006568B (en)
WO (1) WO2009130515A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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WO2012155189A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for estimating neural recruitment - f
DK3357533T3 (en) 2011-05-13 2021-11-15 Saluda Medical Pty Ltd DEVICE FOR CONTROLLING A NEURAL STIMULUS
CA2835486C (en) 2011-05-13 2022-07-19 Saluda Medical Pty Limited Method and apparatus for measurement of neural response - a
WO2012155184A1 (en) * 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for measurement of neural response - c
WO2012155185A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for measurement of neural response
WO2012155187A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for application of a neural stimulus - i
US9872990B2 (en) 2011-05-13 2018-01-23 Saluda Medical Pty Limited Method and apparatus for application of a neural stimulus
EP2908904B1 (en) 2012-11-06 2020-09-23 Saluda Medical Pty Limited System for controlling electrical conditions of tissue
US11172864B2 (en) 2013-11-15 2021-11-16 Closed Loop Medical Pty Ltd Monitoring brain neural potentials
JP6671021B2 (en) 2013-11-22 2020-03-25 サルーダ・メディカル・ピーティーワイ・リミテッド Method and device for detecting a neural response in a neural measurement
ES2801348T3 (en) 2014-05-05 2021-01-11 Saluda Medical Pty Ltd Improved neurological measurement
EP3838331B1 (en) 2014-07-25 2024-05-22 Saluda Medical Pty Limited Neural stimulation dosing
US10597636B2 (en) 2014-09-19 2020-03-24 University Of Florida Research Foundation, Inc. Electroactive polymeric scaffolds and method for delivering nerve growth factor to nerve tissue
AU2015349614B2 (en) 2014-11-17 2020-10-22 Saluda Medical Pty Ltd Method and device for detecting a neural response in neural measurements
WO2016090420A1 (en) 2014-12-11 2016-06-16 Saluda Medical Pty Ltd Implantable electrode positioning
EP4285985A3 (en) 2014-12-11 2024-01-17 Saluda Medical Pty Ltd Method and device for feedback control of neural stimulation
WO2016115596A1 (en) 2015-01-19 2016-07-28 Saluda Medical Pty Ltd Method and device for neural implant communication
AU2016245335B2 (en) 2015-04-09 2020-11-19 Saluda Medical Pty Ltd Electrode to nerve distance estimation
JP2018516150A (en) 2015-05-31 2018-06-21 サルーダ・メディカル・ピーティーワイ・リミテッド Cranial nerve activity monitoring
EP3302692B1 (en) 2015-05-31 2024-07-24 Closed Loop Medical Pty Ltd Brain neurostimulator electrode fitting
CA2980482C (en) 2015-06-01 2023-09-26 Saluda Medical Pty Ltd Motor fibre neuromodulation
CA3019701A1 (en) 2016-04-05 2017-10-12 Saluda Medical Pty Ltd Improved feedback control of neuromodulation
EP3474747A4 (en) 2016-06-24 2020-01-22 Saluda Medical Pty Ltd Neural stimulation for reduced artefact
WO2018232145A1 (en) * 2017-06-14 2018-12-20 Wichita State University Apparatus and method for neural regeneration
US10589089B2 (en) 2017-10-25 2020-03-17 Epineuron Technologies Inc. Systems and methods for delivering neuroregenerative therapy
EP3700617A4 (en) 2017-10-25 2021-08-04 Epineuron Technologies Inc. Systems and methods for delivering neuroregenerative therapy
CN112334184A (en) 2018-04-27 2021-02-05 萨鲁达医疗有限公司 Nerve stimulation of mixed nerves
US11247043B2 (en) 2019-10-01 2022-02-15 Epineuron Technologies Inc. Electrode interface devices for delivery of neuroregenerative therapy

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060089751A1 (en) * 1997-01-27 2006-04-27 Ewa Herbst Electronic delivery systems and methods with feedback
US20060194724A1 (en) * 2005-02-25 2006-08-31 Whitehurst Todd K Methods and systems for nerve regeneration
WO2006108262A2 (en) * 2005-04-15 2006-10-19 Lozano Andres M Regulation of neurotrophins
WO2008005843A2 (en) * 2006-06-30 2008-01-10 Cyberkinetics Neurotechnology Systems, Inc. Nerve regeneration system and lead devices associated therewith

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060089751A1 (en) * 1997-01-27 2006-04-27 Ewa Herbst Electronic delivery systems and methods with feedback
US20060194724A1 (en) * 2005-02-25 2006-08-31 Whitehurst Todd K Methods and systems for nerve regeneration
WO2006108262A2 (en) * 2005-04-15 2006-10-19 Lozano Andres M Regulation of neurotrophins
WO2008005843A2 (en) * 2006-06-30 2008-01-10 Cyberkinetics Neurotechnology Systems, Inc. Nerve regeneration system and lead devices associated therewith

Also Published As

Publication number Publication date
EP2307090A2 (en) 2011-04-13
WO2009130515A2 (en) 2009-10-29
WO2009130515A3 (en) 2010-04-01

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Legal Events

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PG Patent granted
ML Lapse due to non-payment of fees

Effective date: 20131104