WO2009112301A3 - Polypeptidwirkstoffe in der form von konjugaten aus keratinbindenden polypeptiden, polymeren und effektormolekülen, verfahren zu ihrer herstellung und ihre verwendung - Google Patents
Polypeptidwirkstoffe in der form von konjugaten aus keratinbindenden polypeptiden, polymeren und effektormolekülen, verfahren zu ihrer herstellung und ihre verwendung Download PDFInfo
- Publication number
- WO2009112301A3 WO2009112301A3 PCT/EP2009/050847 EP2009050847W WO2009112301A3 WO 2009112301 A3 WO2009112301 A3 WO 2009112301A3 EP 2009050847 W EP2009050847 W EP 2009050847W WO 2009112301 A3 WO2009112301 A3 WO 2009112301A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- keratin
- polypeptide
- conjugates
- production
- polymer chain
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/10—Preparations for permanently dyeing the hair
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
Abstract
Keratinbindende Polypeptidwirkstoffe in der Form von Konjugaten (A'B'C') oder (A'B'C'D'), umfassend (A') eine Polypeptidsequenz, abgeleitet von einem keratinbindenden Polypeptid (A), (B') im statistischen Mittel mindestens eine Polymerkette, die von einem wasserlöslichen oder wasserdispergierbaren, seitenständige und/oder endständige reaktive funktionelle Gruppen (b1 ) tragenden Polymer (B) abgeleitet ist, das danach ausgewählt ist, dass es zusammen mit dem zum Konjugat (A'B'C) oder (A'B'C'D') umzusetzenden keratinbindenden Polypeptid (A) im Normzustand eine homogene wässrige Lösung oder Dispersion, worin das Polypeptid (A) noch immer eine keratinbindende Aktivität aufweist, bildet, wobei (C') mindestens eine Linkergruppe die Polymerkette (B') mit der Polypeptidsequenz (A') verbindet und wobei (D') gegebenenfalls im statistischen Mittel mindestens eine Effektorgruppe an die Polymerkette (B') gebunden ist; Verfahren zu ihrer Herstellung und ihre Verwendung zur Modifizierung von Keratin und keratinhaltigen Materialien sowie zur Herstellung von kosmetischen und pharmazeutischen Zusammensetzungen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08102426.7 | 2008-03-10 | ||
EP08102426 | 2008-03-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009112301A2 WO2009112301A2 (de) | 2009-09-17 |
WO2009112301A3 true WO2009112301A3 (de) | 2009-12-10 |
Family
ID=41065593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2009/050847 WO2009112301A2 (de) | 2008-03-10 | 2009-01-26 | Polypeptidwirkstoffe in der form von konjugaten aus keratinbindenden polypeptiden, polymeren und effektormolekülen, verfahren zu ihrer herstellung und ihre verwendung |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009112301A2 (de) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004113394A2 (en) * | 2003-06-20 | 2004-12-29 | Warwick Effect Polymers Limited | Living radical polymerization initiator comprising a functional group capable of reacting with polypeptides or the like, comb polymer obtained therewith, polypeptide conjugates and drugs obtained therefrom |
WO2006136607A2 (de) * | 2005-06-24 | 2006-12-28 | Basf Aktiengesellschaft | Verwendung von hydrophobin-polypeptiden sowie konjugaten aus hydrophobin-polypeptiden mit wirk- oder effektstoffen und ihre herstellung sowie deren einsatz in der kosmetik |
WO2007031734A1 (en) * | 2005-09-14 | 2007-03-22 | Ucb Pharma S.A. | Comb polymers |
WO2007060116A2 (de) * | 2005-11-24 | 2007-05-31 | Basf Se | Keratinbindende effektormoleküle und verfahren zu deren herstellung durch kopplung keratinbindender polypeptide mit carboxylgruppen oder sulfonsäuregruppen tragenden effektormolekülen |
WO2007060117A2 (de) * | 2005-11-24 | 2007-05-31 | Basf Se | Chimäre keratinbindende effektorproteine |
WO2007147445A2 (de) * | 2005-11-24 | 2007-12-27 | Basf Se | Keratinbindende effektormoleküle und verfahren zu deren herstellung |
-
2009
- 2009-01-26 WO PCT/EP2009/050847 patent/WO2009112301A2/de active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004113394A2 (en) * | 2003-06-20 | 2004-12-29 | Warwick Effect Polymers Limited | Living radical polymerization initiator comprising a functional group capable of reacting with polypeptides or the like, comb polymer obtained therewith, polypeptide conjugates and drugs obtained therefrom |
WO2006136607A2 (de) * | 2005-06-24 | 2006-12-28 | Basf Aktiengesellschaft | Verwendung von hydrophobin-polypeptiden sowie konjugaten aus hydrophobin-polypeptiden mit wirk- oder effektstoffen und ihre herstellung sowie deren einsatz in der kosmetik |
WO2007031734A1 (en) * | 2005-09-14 | 2007-03-22 | Ucb Pharma S.A. | Comb polymers |
WO2007060116A2 (de) * | 2005-11-24 | 2007-05-31 | Basf Se | Keratinbindende effektormoleküle und verfahren zu deren herstellung durch kopplung keratinbindender polypeptide mit carboxylgruppen oder sulfonsäuregruppen tragenden effektormolekülen |
WO2007060117A2 (de) * | 2005-11-24 | 2007-05-31 | Basf Se | Chimäre keratinbindende effektorproteine |
WO2007147445A2 (de) * | 2005-11-24 | 2007-12-27 | Basf Se | Keratinbindende effektormoleküle und verfahren zu deren herstellung |
Non-Patent Citations (3)
Title |
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BOCZONADI ET AL: "Cytolinker cross-talk: Periplakin N-terminus interacts with plectin to regulate keratin organisation and epithelial migration", EXPERIMENTAL CELL RESEARCH, ACADEMIC PRESS, US, vol. 313, no. 16, 18 September 2007 (2007-09-18), pages 3579 - 3591, XP022257388, ISSN: 0014-4827 * |
KARASHIMA TADASHI ET AL: "Interaction of periplakin and envoplakin with intermediate filaments.", JOURNAL OF CELL SCIENCE, vol. 115, no. 24, 15 December 2002 (2002-12-15), pages 5027 - 5037, XP002548574, ISSN: 0021-9533 * |
LECHLER TERRY ET AL: "Desmoplakin: An unexpected regulator of microtubule organization in the epidermis", JOURNAL OF CELL BIOLOGY, vol. 176, no. 2, January 2007 (2007-01-01), pages 147 - 154, XP002548576, ISSN: 0021-9525 * |
Also Published As
Publication number | Publication date |
---|---|
WO2009112301A2 (de) | 2009-09-17 |
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