WO2009096803A1

WO2009096803A1 - 'expromt' bottle

Info

Publication number: WO2009096803A1
Application number: PCT/RU2008/000044
Authority: WO
Inventors: Alexandr Andreyevich Pampurin
Original assignee: Skvortsov, Igor Victorovich
Priority date: 2008-01-29
Filing date: 2008-01-29
Publication date: 2009-08-06

Abstract

The invention relates to medicine and can be used for storing medicinal agents. The inventive bottle comprises a movable tube with longitudinal holes, which tube is arranged in the elongated bottleneck with a fixing ring in such a way that the tube is axially displaceable between the annular recesses made on the outer surface of the tube and a toothed strap for holding a cap in a determined position, wherein the annular recesses with a serrated surface are made on the bottle and the cap. The invention makes it possible to reliably storing a soluble substance and a solvent and to produce a solution without breaking the insulation between the content and environment.

Description

Vial "EXPROMT

The present invention - the bottle "Export" - relates to the field of medical industry and can be used to store drugs and prepare sterile solutions.

Known pharmaceutical container for two individual substances with a mixing and dosing device, protected by RF patent Na 2157682. Its disadvantage is that when using it it is problematic to choose the prepared solution with a needle in an injection syringe.

The objective of the invention is to create conditions for the separate storage of dry medicinal substance and solvent "in one package", the rapid preparation of the solution while maintaining sterility, as well as the convenience of choosing the prepared solution with a needle into the syringe for injection.

The problem is solved using the bottle “Export”, in which, thanks to the special shape of the neck, a tube with the possibility of axial movement is installed, which allows you to keep the drug and solvent isolated from each other and from the environment and, if necessary, prepare the solution without violating the isolation of the contents of the bottle, tubes and the prepared solution from the environment.

The bottle "Impromptu" is illustrated by drawings: figure 1 - General view of figure 2 - General view in section, Fig.Z - in the assembled state in a section, figure 4 - in working condition in a section.

The bottle "Express", General view - figure 1, where the positions indicated:

1 - a bottle, 2 - a gear tape, 3 - a cover.

The bottle "Express", a General view in section - figure 2, the positions indicated:

SUBSTITUTE SHEET (RULE 26) 1 - bottle with an extended neck, solid product.

The bottle is a hollow cylinder, the upper end of which passes into an elongated neck. The elongated neck, which runs parallel to the O-O axis, has a screw thread 11 on the outer surface for screwing on the cover 3. On the inner surface in the upper part of the elongated neck there is an annular recess 6 for installing a retaining ring 7 of elastic material, for fixing the test tube 14. On the upper the edge of the cylindrical surface of the bottle is made of an annular recess 4 with a serrated surface for installing the toothed belt 2 (figure 1).

2 - a gear tape. The gear belt has protrusions and depressions that correspond to the gear surface in the annular recesses on the bottle 1 (figure 2) and the lid 3 (figure 2). Toothed tape is placed in annular recesses with a toothed surface on the bottle and on the lid. With its width, it sets the distance by which the cover should move when tightening. Entering meshing with the toothed surface in the annular recess 4 (FIG. 2) of the bottle 1 and with the toothed surface in the annular recess 5 (FIG. 2) of the lid 3, prevents the lid from rotating relative to the vial.

3 - cover. The lower part of the lid on the outside has an annular recess with a toothed surface 5 for laying the toothed belt 2, (figure 2). On the inner surface of the walls of the cap there is a screw thread for screwing onto the threaded part of the neck of the bottle 1 (Fig.2 and 3). The inner surface of the bottom of the lid is a flat circle. ^•

4 - an annular recess with a serrated surface on the bottle.

5 - an annular recess with a serrated surface on the lid.

6 - annular recess for installing the retaining ring 7.

7 - a fixing ring of elastic material.

8 - an annular recess for fixing the tubes in the "storage" position.

9 - an annular recess for fixing the tubes in the "solution" position.

SUBSTITUTE SHEET (RULE 26) 10 - plug, clogging the tube 14 (figure 2).

11 - screw thread for screwing the cap 3 (cig. 2).

12 - the freely protruding end of the gear belt 2 (Fig.1-3), for the convenience of its removal.

13 - longitudinal holes of the movable tube 14 (figure 2). The number and size of holes depends on the diameter of the tube. The total opening area of the holes may be equal to or greater than the cross-sectional area of the tube.

14 - a movable tube with longitudinal holes 13 (figure 2). In the lower part of the test tube, at some distance from the conditional annular line of transition of the convex bottom surface to the cylindrical surface of the test tube wall, there are longitudinal holes 13. There are two annular recesses on the outer surface of the upper part of the test tube: 8 - “storage” and 9 - “solution”, located at a distance from each other equal to the distance by which the tube moves from the “storage” position to the “Dissolution” position. On top of the tube is closed by a stopper 10 of elastic material, through which the syringe needle can easily penetrate.

The bottle "Export" in the assembled state in the context is illustrated in Fig. C: the movable tube 14 is installed in the neck and is fixed by the locking ring 7 in the "storage" position. The top of the tube is closed by stopper 10. Being in the “storage” position, the outer surface of the tube is covered by the inner surface of the neck. By blocking the longitudinal holes 13 of the tube 14, as well as covering part of the surface of the tube below and above the longitudinal holes, the inner surface of the neck isolates the internal volume of the tube both from the environment and from the internal volume of the vial. The internal volume of the vial is also isolated from the environment. The bottle 1 and the movable tube 14 are filled with the required amount of soluble substance and solvent, moreover, the solvent and soluble substance can occupy different positions: the soluble substance in the test tube is the solvent in the bottle or vice versa. Cap 3 is screwed onto the neck of bottle 1 until it touches

SUBSTITUTE SHEET (RULE 26) the plane of the bottom of the lid with the end of the movable test tube 14. In the gap between the lid and the bottle in the annular recesses 4 and 5 with the toothed surface, a toothed belt 2 is laid (Figs. 1-3).

The operation of the bottle "Export" is illustrated in figure 4 and proceeds as follows: to prepare the solution, remove the toothed belt 2. The cap 3 is screwed to the stop until it stops. When screwing, the inner plane of the bottom of the cover 3 moves along the axis 0-0 down. Sliding along the end of the movable tube 14, the inner surface of the bottom of the lid 3 exerts increasing pressure on the movable tube, forcing it to translate along the O-O axis. When moving the longitudinal holes 13 of the movable test tube partially out of the scope of the test tube with the inner surface of the neck - will merge the volume of the test tube and vial. The movement of the movable test tube will continue until the inner surface of the lid 3 adheres to the end surface of the neck of the vial. Further screwing of the cover will become impossible. The transferred tube is fixed with the locking ring 7 in the “open” position. For the best mixing of the components, the vial is shaken.

The finished solution is isolated from the environment, sterility is maintained. To select the prepared solution, the cap is screwed up, the bottle is turned upside down and the tube plug is pierced with a syringe needle. The longitudinal openings of the tube, continuing into the neck, contribute to the complete draining of the solution from the vial into the tube. The transparency of the neck of the vial and the tube allows you to control the position of the syringe needle inserted into the tube through the elastic tube, as well as the selection of the prepared solution in the syringe. The size of the vial and test tube, and therefore, their volumes can be of any size and depend on the amount of solvent substance to be dissolved, necessary to obtain a certain amount of solution of a certain concentration.

Reliability and ease of operation of the “neck-to-sample” system requires special preparation of mating surfaces

SUBSTITUTE SHEET (RULE 26) necks and test tubes. Moving the tube in the neck should not require much effort, during storage, sufficient tightness should be maintained to isolate the internal volume of the tube from the environment and from the internal volume of the vial, and after preparation of the solution, to isolate the total volume from the environment.

The bottle "Export", keeping the drug substance and solvent isolated from each other and from the environment, allows you to quickly prepare a solution while fully maintaining sterility. It eliminates a number of manipulations with the ampoule in the case of using separately stored components - in the ampoule and in the bottle. The entrance to the tube from the side of the tube is larger than the opening of the opened ampoule, and it is easier to get into it with a needle. In this case, there is absolutely no contact of the soluble substance, solvent and the prepared solution with the environment, which cannot be avoided even when opening the ampoule, as well as when choosing a liquid in the syringe, when the released volume of the ampoule is filled with ambient air. According to the author, such qualities of the “Export” bottle can be very important in emergency situations: in conditions of smoke, dust, or increased infectious danger.

SUBSTITUTE SHEET (RULE 26)

Claims

CLAIM

1. A bottle for storing drugs and preparing sterile solutions, including a screw-threaded cap, characterized in that it contains a toothed tape and a tube with longitudinal holes mounted in an elongated neck of the bottle, equipped with a retaining ring mounted in the annular recess, while the tube has the possibility of axial movement between the annular recesses on the outer surface of the tube and the exit of the holes from the scope of the tube with the inner surface of the neck, the gear belt is removed my in the preparation of the solution and having the ability to hold the lid during storage and on the bottle cap and annular recesses formed with a serrated surface for laying the toothed belt.

SUBSTITUTE SHEET (RULE 26)