WO2009091346A3 - Formulation pharmaceutique stable et procédés de préparation - Google Patents

Formulation pharmaceutique stable et procédés de préparation Download PDF

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Publication number
WO2009091346A3
WO2009091346A3 PCT/TR2009/000002 TR2009000002W WO2009091346A3 WO 2009091346 A3 WO2009091346 A3 WO 2009091346A3 TR 2009000002 W TR2009000002 W TR 2009000002W WO 2009091346 A3 WO2009091346 A3 WO 2009091346A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical formulation
preparation methods
stable pharmaceutical
dihydroxyhept
methylsulfonyl
Prior art date
Application number
PCT/TR2009/000002
Other languages
English (en)
Other versions
WO2009091346A2 (fr
Inventor
Ramazan Sivasligil
Serap Odabasi
F . Bilgehan Perveli
Nalan Sarikas
Selen Ural
Original Assignee
Bilim Ilac Sanayi Ticaret A . S .
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bilim Ilac Sanayi Ticaret A . S . filed Critical Bilim Ilac Sanayi Ticaret A . S .
Publication of WO2009091346A2 publication Critical patent/WO2009091346A2/fr
Publication of WO2009091346A3 publication Critical patent/WO2009091346A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne des compositions pharmaceutiques, en particulier un acide bis[(E)-7-[4-(4- fluorophényl-6-isopropyl-2-[méthyl(méthylsulfonyl)amino]pyrimidin-5-yl]-(3R, 5S)-3,5- dihydroxyhept-6-énoïque] ou des sels pharmaceutiquement acceptables (désignés ci-après par la formule I) de ce dernier, en particulier des sels de sodium et de calcium, caractérisées en ce qu'elles renferment un agent de tamponnage dans lequel le cation est monovalent.
PCT/TR2009/000002 2008-01-15 2009-01-14 Formulation pharmaceutique stable et procédés de préparation WO2009091346A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2008/00269 2008-01-15
TR2008/00269A TR200800269A2 (tr) 2008-01-15 2008-01-15 Stabil farmasötik formülasyon ve hazırlama yöntemleri

Publications (2)

Publication Number Publication Date
WO2009091346A2 WO2009091346A2 (fr) 2009-07-23
WO2009091346A3 true WO2009091346A3 (fr) 2009-10-01

Family

ID=40756485

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2009/000002 WO2009091346A2 (fr) 2008-01-15 2009-01-14 Formulation pharmaceutique stable et procédés de préparation

Country Status (2)

Country Link
TR (1) TR200800269A2 (fr)
WO (1) WO2009091346A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6573098B2 (ja) * 2014-10-14 2019-09-11 日本ジェネリック株式会社 安定なロスバスタチンカルシウム錠剤

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0521471A1 (fr) * 1991-07-01 1993-01-07 Shionogi Seiyaku Kabushiki Kaisha Dérivés de pyrimidine comme inhibiteurs de la HMG-CoA reductase
WO2005041939A1 (fr) * 2003-11-04 2005-05-12 Athpharma Limited Formulations pharmaceutiques de statines de diffusion assistee par des porteurs et leurs utilisations
US20070202159A1 (en) * 2006-02-02 2007-08-30 Mathur Rajeev S Pharmaceutical composition comprising stabilized statin particles
WO2008035128A1 (fr) * 2006-09-18 2008-03-27 Richter Gedeon Nyrt. Compositions pharmaceutiques contenant de la rosuvastatine calcique
WO2008062476A2 (fr) * 2006-10-31 2008-05-29 Glenmark Pharmaceutical Limited Composition pharmaceutique comprenant de la rosuvastatine ou un sel de qualité pharmaceutique de cette substance

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0521471A1 (fr) * 1991-07-01 1993-01-07 Shionogi Seiyaku Kabushiki Kaisha Dérivés de pyrimidine comme inhibiteurs de la HMG-CoA reductase
WO2005041939A1 (fr) * 2003-11-04 2005-05-12 Athpharma Limited Formulations pharmaceutiques de statines de diffusion assistee par des porteurs et leurs utilisations
US20070202159A1 (en) * 2006-02-02 2007-08-30 Mathur Rajeev S Pharmaceutical composition comprising stabilized statin particles
WO2008035128A1 (fr) * 2006-09-18 2008-03-27 Richter Gedeon Nyrt. Compositions pharmaceutiques contenant de la rosuvastatine calcique
WO2008062476A2 (fr) * 2006-10-31 2008-05-29 Glenmark Pharmaceutical Limited Composition pharmaceutique comprenant de la rosuvastatine ou un sel de qualité pharmaceutique de cette substance

Also Published As

Publication number Publication date
TR200800269A2 (tr) 2009-08-21
WO2009091346A2 (fr) 2009-07-23

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