TR200800269A2 - Stabil farmasötik formülasyon ve hazırlama yöntemleri - Google Patents

Stabil farmasötik formülasyon ve hazırlama yöntemleri

Info

Publication number
TR200800269A2
TR200800269A2 TR2008/00269A TR200800269A TR200800269A2 TR 200800269 A2 TR200800269 A2 TR 200800269A2 TR 2008/00269 A TR2008/00269 A TR 2008/00269A TR 200800269 A TR200800269 A TR 200800269A TR 200800269 A2 TR200800269 A2 TR 200800269A2
Authority
TR
Turkey
Prior art keywords
pharmaceutical formulation
preparation methods
stable pharmaceutical
dihydroxyhept
methylsulfonyl
Prior art date
Application number
TR2008/00269A
Other languages
English (en)
Inventor
Si̇vasligi̇l Ramazan
Odabaşi Serap
Bi̇lgehan Perveli̇ F.
Original Assignee
Bi̇li̇m İlaç Sanayi̇ Ti̇caret A.Ş.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bi̇li̇m İlaç Sanayi̇ Ti̇caret A.Ş. filed Critical Bi̇li̇m İlaç Sanayi̇ Ti̇caret A.Ş.
Priority to TR2008/00269A priority Critical patent/TR200800269A2/tr
Priority to PCT/TR2009/000002 priority patent/WO2009091346A2/en
Publication of TR200800269A2 publication Critical patent/TR200800269A2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim

Abstract

Bu buluş farmasötik bileşimler ve özellikle bis[(E)-7-[4-(4-florofenil)-6-isopropil-2-[metil(me ilsülfonil)amino] pirimidin-5-il](3R,5S)-3,5-dihidroksihept-6-enoik asit] içeren bir farmasötik bileşim veya bunun farmasötik olarak kabul edilebilir (bundan sonra 'Formül I olarak bahsedilecek) bir tuzu, özellikle sodyum ve kalsiyum tuzları ve özellikle kalsiyum tuzu (bundan sonra I numaralı formülün) bis[(E)-7-[4-(4-florofenil)-6-isopropil-2-[metil(me ilsülfonil)amino] pirimidin-5-il](3R,5S)-3,5-dihidroksihept-6-enoik asit] kalsiyum tuzu ile ilgili olup içindeki katyonun tek değerli olduğu tamponlayıcı madde içermesi ile karakterize edilmektedir.@
TR2008/00269A 2008-01-15 2008-01-15 Stabil farmasötik formülasyon ve hazırlama yöntemleri TR200800269A2 (tr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TR2008/00269A TR200800269A2 (tr) 2008-01-15 2008-01-15 Stabil farmasötik formülasyon ve hazırlama yöntemleri
PCT/TR2009/000002 WO2009091346A2 (en) 2008-01-15 2009-01-14 Stable pharmaceutical formulation and preparation methods

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2008/00269A TR200800269A2 (tr) 2008-01-15 2008-01-15 Stabil farmasötik formülasyon ve hazırlama yöntemleri

Publications (1)

Publication Number Publication Date
TR200800269A2 true TR200800269A2 (tr) 2009-08-21

Family

ID=40756485

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2008/00269A TR200800269A2 (tr) 2008-01-15 2008-01-15 Stabil farmasötik formülasyon ve hazırlama yöntemleri

Country Status (2)

Country Link
TR (1) TR200800269A2 (tr)
WO (1) WO2009091346A2 (tr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6573098B2 (ja) * 2014-10-14 2019-09-11 日本ジェネリック株式会社 安定なロスバスタチンカルシウム錠剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2648897B2 (ja) * 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
US8987322B2 (en) * 2003-11-04 2015-03-24 Circ Pharma Research And Development Limited Pharmaceutical formulations for carrier-mediated transport statins and uses thereof
EP1905424A3 (en) * 2006-02-02 2008-04-30 Ranbaxy Laboratories Limited Process for the preparation of a pharmaceutical composition comprising stabilized statin particles
HU227610B1 (en) * 2006-09-18 2011-09-28 Richter Gedeon Nyrt Pharmaceutical compositions containing rosuvastatin potassium
WO2008062476A2 (en) * 2006-10-31 2008-05-29 Glenmark Pharmaceutical Limited Pharmaceutical composition comprising rosuvastatin or pharmaceutically accepatble salts thereof

Also Published As

Publication number Publication date
WO2009091346A3 (en) 2009-10-01
WO2009091346A2 (en) 2009-07-23

Similar Documents

Publication Publication Date Title
CY1107225T1 (el) Κρυσταλλικα αλατα του 7-[4-(4-φθοροφαινυλ)-6-ισοπροπυλ-2-[μεθυλ(μεθυλσουλφονυλ)αμινο]πυριμιδιν-5-υλ]-(3r,5s)-3-5-διυδροξυεπτ-6-ενοϊκου οξεος
MY122707A (en) Pharmaceutical compositions
IS8385A (is) Kristallað form bis [(E)-7-[4-(4-flúorfenýl)-6-ísóprópýl-2-[metýl(metýlsúlfónýl) amínó] pýrimídin-5-ýl](3R, 5S)-3,5-díhýdroxýhept-6-ensýru] kalsíumsalts
TWI341310B (en) Improved production of (e)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3r,5s)-3,5-dihydroxyhept-6-enoic acid calcium salt
TR200101894T2 (tr) Kristalimsi bis[(E)]-7-[4-(4-flüorofenil)-6- izopropil-2-[metil(metilsülfonil)amino] pirimidin-5-il](3R,5S)-3, 5-dihidroksihept-6-enoik asit] kalsiyum tuzu.
EA200801447A1 (ru) Фармацевтическая композиция
TR200800269A2 (tr) Stabil farmasötik formülasyon ve hazırlama yöntemleri
WO2010030201A3 (en) Stable oral pharmaceutical composition containing a pharmaceutically acceptable salt of [(e)-7-[4-(4-fluorophenyl)-6-isopropyl-2- [methyl(methylsulfonyl)amino]pyrimidine-5-yl] (3r, 5s) - 3,5 dihydroxyhept-6- enoic acid
ATE553098T1 (de) Verfahren zur herstellung von rosuvastatin- calcium
MX2010011006A (es) Nueva sal de un derivado de pirimidina.
UY30336A1 (es) Composiciones farmacéuticas conteniendo ácido (e)-7-(4-(4-fluorofenil)-6-isopropil-2-(metil(metilsulfonil)amino)pirimidin-5-il)-(3r,5s)-3,5-dihidroxihept-6-enoico y sales farmacéuticamente aceptables de la misma
AR043562A1 (es) Composiciones farmaceuticas solidas que comprende el acido bis (e)-7-[4-(4- fluorfenil-6-isopropil-2 [metil (metilsulfonil)amino] pirimidin-5-il]-(3r, 5s)-3,5-dihidroxi-hept-6-enoico o sus sales farmaceuticamente aceptables y un agente surfactante con una estabilidad fisico -quimica y velocidad de d
DOP2005000017A (es) Composiciones farmaceuticas solidas que comprende el acido bis (e)-7-[4-(4-fluorfenil-6-isopropil-2-[metil(metilsulfonil)amino]pirimidin-5-il]-(3r,5s)-3,5-dihidroxi-hept-6-enoico o sus sales farmaceuticamente aceptable y un agenta surfactante con una estabilidad fisico-quimica y velocidad de disolucion aumentada, procedimiento para preparar dicha composicion y uso de esta composicion para preparar un medicamento
UY27271A1 (es) Composiciones farmacéuticas
UY28575A1 (es) Composiciones farmacéuticasa sólidas que comprende el ácido bis (e)-7-(4-(4-fluorfenil-6 -isopropil-2- (metil (metilsulfonil) amino) pirimidin- 5-il) -3r,5s)-3,5- dihidroxo- ............
CY1115610T1 (el) Μορφολινο πυριμιδινες και η χρηση τους στη θεραπεια