WO2009082252A1 - Méthode d'action électrique sur un organisme vivant - Google Patents

Méthode d'action électrique sur un organisme vivant Download PDF

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Publication number
WO2009082252A1
WO2009082252A1 PCT/RU2007/000724 RU2007000724W WO2009082252A1 WO 2009082252 A1 WO2009082252 A1 WO 2009082252A1 RU 2007000724 W RU2007000724 W RU 2007000724W WO 2009082252 A1 WO2009082252 A1 WO 2009082252A1
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WO
WIPO (PCT)
Prior art keywords
skin
electrodes
action
pulses
electrical
Prior art date
Application number
PCT/RU2007/000724
Other languages
English (en)
Russian (ru)
Inventor
Yakov Zalmanovich Grinberg
Mikhail Anatolievich Unakafov
Original Assignee
Zakrytoye Aktsionernoye Obshestvo Osoboye Konstruktorskoye Byuro 'ritm'
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zakrytoye Aktsionernoye Obshestvo Osoboye Konstruktorskoye Byuro 'ritm' filed Critical Zakrytoye Aktsionernoye Obshestvo Osoboye Konstruktorskoye Byuro 'ritm'
Priority to PCT/RU2007/000724 priority Critical patent/WO2009082252A1/fr
Publication of WO2009082252A1 publication Critical patent/WO2009082252A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/002—Using electric currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/205—Applying electric currents by contact electrodes continuous direct currents for promoting a biological process
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36031—Control systems using physiological parameters for adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters

Definitions

  • the invention relates to medicine and medical equipment, in particular, to methods of electric action on a living organism, and can be used for therapeutic, rehabilitative, preventive purposes, as well as in the field of research related to studying the effect of various factors on a living organism.
  • the method of electrical effects on a living organism described in the description of the patent of the Russian Federation N ° 2161904, IPC 7 A61B 5/05, A61H 39/00 on the invention "Method for assessing the electrophysiological state of a person and device for its implementation", published on 01.20.2001, consists in installing active and passive electrodes on the skin, connecting high-quality inductance coils to the active and passive electrodes saturated with electromagnetic energy, passing through the interelectrode tissue the electrical vibrations arising in vibrational circuit formed by the circuit: active electrode - high-quality inductor - passive electrode - interelectrode fabric - active electrode, and impact assessment based on the results of measuring the frequency, or amplitude, or attenuation of these oscillations.
  • the disadvantage of this method is the lack of an additional therapeutic effect associated with vibrations of the sub-electrode tissues, as well as a subjective assessment of the “accuracy” of the level of exposure, since the setting of this level is made solely according to the patient’s feelings.
  • the problem to which the invention is directed is to increase therapeutic efficacy and optimize the level and time of exposure of existing methods of electric exposure to a living organism.
  • the technical result when using the proposed method of electric action on a living organism is to increase the effectiveness of therapy due to the high amplitude of the acting pulses, the complex nature of the effect (simultaneous exposure to electric pulses and high-frequency massage). It also provides the ability to control both the duration of the electric effect and the change in the shape of the electric signal depending on objective changes in the sub-electrode tissues, in the objective nature of ensuring the “accuracy” of the level of exposure, the criterion of which is the presence of vibrations (“sounding” of the skin) upon exposure, and A means to achieve a sufficient but non-damaging level of exposure is to use a shock excitation circuit consisting of an inductance uyuschego subelectrode device and the container.
  • the technical result is achieved by the fact that in the method of electric exposure to a living organism, including installing electrodes on the skin and passing an electric signal through them, controlling the signal depending on the course of electrochemical processes that occur on the skin as a result of the interaction of the electrodes and the electric signal with the skin coverings, electric pulses are passed through the electrodes from the inductor, while using high-amplitude pulses, causing vibrations of subelements native tissue.
  • Another feature of the invention is that the change in the amplitude of the action, the shape of the pulses, the modulation of the signal and the moment the exposure ends also depends on changes in the impedance of the subelectrode tissues resulting from the electropulse effect on the skin.
  • a waveform is meant both the actual form of a single signal and the parameters of a series of pulses (frequency of bursts of pulses, the number and frequency of pulses in a packet, the nature of the change in the amplitude of the pulses, etc.).
  • Another feature of the invention is the control of the amplitude, shape, modulation of pulses, the moment of termination of exposure, depending on the characteristics of the sound arising from skin vibrations as a result of electrical exposure.
  • the “minimum sufficiency” of its energy is defined as the minimum energy that objectively causes a response in the form of a change, for example, the impedance of the sub-electrode tissues and / or the appearance of sound arising from skin vibrations as a result of electrical exposure.
  • To establish a “minimally sufficient)) exposure time determine the time during which, for example, by a predetermined amount of the source impedance will change at the site of exposure or the characteristics of the sound arising from skin vibrations as a result of electrical exposure.
  • FIG. 1 shows the type of signal before touching the skin.
  • FIG. 2 - FIG. Figure 5 shows the dynamics of the waveform, characteristic of a change in the predominantly double layer capacity.
  • FIG. 6 - FIG. Figure 9 shows the dynamics of the waveform characteristic of a joint change in the double layer capacity and active resistance.
  • FIG. 10 shows the equivalent electrical circuit of the sub-electrode tissues. (R dc and C dc are the resistance and capacity of the double layer, R tk is the resistance of underlying tissues.)
  • FIG. Figure 11 shows the change in the capacity of the double layer and the active resistance in time (the time is indicated horizontally, the resistance R and the capacity of the double layer C are indicated vertically).
  • FIG. 12 is a spectrum at the first second of exposure; FIG. 13 - on the 20th second.
  • FIG. 1 ... Fig. 9 horizontally shows the time in milliseconds, and vertically - the voltage in volts.
  • FIG. 11 horizontally - time, vertically - resistance R and the capacity of the double layer C.
  • the claimed method is as follows. An inductor is used as a source of electrical impulses, to the ends of which two electrodes are connected. During the first phase of the formation of a single pulse, a constant voltage source is connected to the coil.
  • the source is disconnected from the inductor and in the circuit formed by the inductor, its own stray capacitance, skin impedance (if the electrodes are connected to the patient), free vibrations occur, the parameters of which depend on all the indicated components of the circuit.
  • the second phase of the pulse begins, which will end when the oscillations in the specified circuit are completed.
  • an inductor as a source of electrical pulses makes it easy to control the energy of a single pulse by changing the duration of the first phase.
  • the energy transmitted by a single impulse to the patient weakly depends on the characteristics of the subelectrode tissues and cannot exceed the energy accumulated by the coil during the first phase.
  • FIG. 1 shows the type of signal before touching the skin.
  • the amplitude of the open circuit voltage can reach 600V.
  • the electrodes are applied to the skin of a person or animal in an area near the exposure zone.
  • the current density depending on the area of the electrode and individual sensitivity is 5-50mA / cm 2 , which is 50-500 times higher than that with traditional methods of electrotherapy.
  • the limit value of the current density is usually 0.1 mA / cm. [Bogolyubov BM, Ponomarenko G.N. General physiotherapy: a textbook. - Ed. Ze, rev. And add. - M .: Medicine, 2003, P.102 ]).
  • the safety of exposure is ensured by limiting the energy of a single pulse due to its short duration (pulse duration is usually tens of microseconds).
  • FIGs. 2 and 6 show the signal immediately after the electrode is placed on the skin.
  • the maximum amplitude of the electric effect is determined by individual sensations: subthreshold, comfortable, subcomfortable, depending on the technique, while the remaining parameters of the electric effect (number of pulses in a packet, pulse repetition rate, etc.) are set manually or automatically.
  • the amplitude thus determined is maximum in the sense that further automatic control of its value can occur in the range from the minimum possible to the set value, without exceeding it.
  • the electrodes are mounted directly on the area of influence determined by known methods, for example, on the Zakharyin-Gedda zone or on the projection of organs. When the electrodes come into contact with the skin surface, which is, in general, a complex complex of aqueous solutions, a number of processes occur at the metal-solution interface.
  • FIG. Figure 11 shows the change in the capacity of the double layer and the active resistance in time (the time is indicated horizontally, the resistance R and the capacity of the double layer C are indicated vertically).
  • the change in the capacity of the double layer and active skin resistance reflects changes in the metabolic processes that occur on the skin as a result of the interaction of the electrodes and the electrical signal with the skin.
  • This makes it possible to control the duration of the electric exposure and the change in the shape of the electric signal depending on the course of the electrochemical processes, and the duration of the exposure is controlled, for example, until the stabilization of the electrochemical processes, expressed, for example, in the cessation of significant changes in the capacity of the double layer or capacitance of the double layer and active resistance, and the shape of the electric signal is controlled, for example, parametrically, by changing the capacitance of the double th layer or the double layer capacitance and the resistance included in the hammer driving circuit.
  • FIG. 2 ... Fig. 5 An example of a signal change associated with the formation of a double layer capacitance is shown in FIG. 2 ... Fig. 5.
  • the waveform on all graphs differs only in the period of damped oscillations, which is associated with an increase in the equivalent capacitance of the shock excitation circuit.
  • the change in the shape of the pulses practically ceases (graphs 2c and 2d). Accordingly, for the duration of electrochemical processes, one can take the time from the moment the electrodes were installed until the moment the change in the shape of the pulses ceases.
  • a “high-frequency massage” of the underlying tissues occurs (high-frequency within the limits of the frequency of the pulses and its harmonics).
  • the effect on the interstitial (intercellular) fluid, and, possibly, on the cytoplasm (intracellular fluid) stimulates the transport of fluid and its components (products of cell metabolism, neurotransmitters, neuromodulators, etc.). Acceleration of resorption of edema, elimination of congestion, significant improvement of tissue trophism, lymphatic drainage, restoration of elasticity of individual fibers and their layers occur.
  • the current sub-electrode impedance or separately its resistive or capacitive components are calculated.
  • a skin vibration sensor for example, a microphone or a vibration sensor (vibration sensor) is used, which is installed in the immediate vicinity of the electrodes.
  • a vibration sensor vibration sensor
  • a remote bipolar electrode containing both active and passive electrodes
  • a skin vibration sensor is installed in this electrode.
  • a skin vibration sensor is installed in each of them.
  • the second level of waveform control is provided, for example, by connecting damping (RC) circuits to the coil.
  • damping both the double layer capacitance and the active resistance, as well as the parameters of the damping circuits, influence the waveform simultaneously.
  • damping chains it is possible to reduce the amplitude of free oscillations of the shock excitation circuit and, thus, control the flow of metabolic processes.
  • the third level of waveform control consists in changing the parameters of the pulse packets depending on the duration of the formation of the double layer capacitance or on a joint change in the double layer capacitance and active resistance or depending on the characteristics of sound arising from skin vibrations as a result of electrical exposure.
  • the claimed method of electric action on a living organism allows optimizing the electric effect and its duration, using fairly easy-to-use methods when performing electric action on the skin integument.
  • the invention can find application in diagnostic, therapeutic, rehabilitation, and preventive purposes, as well as in the field of research related to the study of the effect on the living organism of various factors.

Abstract

L'invention concerne la médecine et les équipements médicaux, notamment des procédés pour exercer une action électrique sur un organisme vivant, et peut s'utiliser à des fins de traitement, de réhabilitation, de prévention et dans le domaine des recherches liées à l'étude de l'action de différents facteurs sur un organisme vivant. La méthode d'action électrique sur un organisme vivant consiste à placer des électrodes sur l'épiderme et à faire circuler un courant électrique à travers ces électrodes, à commander les signaux en fonction des processus électrochimiques qui se déclenchent sur l'épiderme suite à l'interaction des électrodes et du signal électrique avec l'épiderme; on fait circuler les impulsions électriques via les électrodes depuis une bobine d'induction et l'on utilise des impulsions à grande amplitude provoquant des vibrations des tissus sous les électrodes. Une autre particularité consiste en ce que la variation de l'amplitude d'action, de la forme des impulsions, de la modulation du signal et du moment de cessation de l'action s'effectue en fonction des variations de l'impédance des tissus sous les électrodes qui apparaissent sous l'effet de l'action des impulsions électriques sur l'épiderme. Une autre particularité de l'invention est la commande de l'amplitude, de la forme, de la modulation des impulsions, du moment de cessation de l'action en fonction des caractéristiques du son qui apparaît lors des vibrations de la peau sous l'effet de l'action électrique. Le procédé se distingue en ce qu'il est possible d'utiliser des électrodes sèches pour exercer l'action électrique.
PCT/RU2007/000724 2007-12-24 2007-12-24 Méthode d'action électrique sur un organisme vivant WO2009082252A1 (fr)

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PCT/RU2007/000724 WO2009082252A1 (fr) 2007-12-24 2007-12-24 Méthode d'action électrique sur un organisme vivant

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2645964C2 (ru) * 2016-03-24 2018-02-28 Закрытое акционерное общество "ОКБ "РИТМ" Способ электровоздействия на живой организм

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990010472A1 (fr) * 1989-03-06 1990-09-20 Osoboe Konstruktorskoe Bjuro 'ritm' Pri Taganrogskom Radiotekhnicheskom Institute Imeni V.D.Kalmykova Procede et dispositif produisant des impulsions electriques destinees a stimuler des objets biologiques
RU2161904C2 (ru) * 1996-10-28 2001-01-20 Карасев Александр Александрович Способ оценки электрофизиологического состояния человека и устройство для его осуществления
RU2005133535A (ru) * 2005-10-31 2007-05-10 Закрытое Акционерное Общество Особое Конструкторское Бюро "РИТМ" (RU) Способ электровоздействия на живой организм и устройство для его осуществления

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990010472A1 (fr) * 1989-03-06 1990-09-20 Osoboe Konstruktorskoe Bjuro 'ritm' Pri Taganrogskom Radiotekhnicheskom Institute Imeni V.D.Kalmykova Procede et dispositif produisant des impulsions electriques destinees a stimuler des objets biologiques
RU2161904C2 (ru) * 1996-10-28 2001-01-20 Карасев Александр Александрович Способ оценки электрофизиологического состояния человека и устройство для его осуществления
RU2005133535A (ru) * 2005-10-31 2007-05-10 Закрытое Акционерное Общество Особое Конструкторское Бюро "РИТМ" (RU) Способ электровоздействия на живой организм и устройство для его осуществления

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BOGOLJUBOV V.M. ET AL., PHYSIOTHERAPY GENERAL. MOSCOW-ST.-PETERSBURG, 1998, pages 97 - 104, ... *
GUBIN NIKOLAI GENNADIEVICH.: "Analiz metodik i realizatsy BRT, predlagaemylkh k ispolzovaniju v gosudarstvennykh i kommercheskikh meditsinskikh strukturakh.", BRT LOMKA SLOZHIVSHIKHSYA STEREOTIPOV., 7 September 2000 (2000-09-07), Retrieved from the Internet <URL:http://health2000.agava.ru/pole/arts/lomkastereo.htm> [retrieved on 20070419] *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2645964C2 (ru) * 2016-03-24 2018-02-28 Закрытое акционерное общество "ОКБ "РИТМ" Способ электровоздействия на живой организм

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