WO2009072555A1 - Cancer vaccine - Google Patents

Cancer vaccine Download PDF

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Publication number
WO2009072555A1
WO2009072555A1 PCT/JP2008/072046 JP2008072046W WO2009072555A1 WO 2009072555 A1 WO2009072555 A1 WO 2009072555A1 JP 2008072046 W JP2008072046 W JP 2008072046W WO 2009072555 A1 WO2009072555 A1 WO 2009072555A1
Authority
WO
WIPO (PCT)
Prior art keywords
cell
peptide
antigen
cancer vaccine
cytotoxic
Prior art date
Application number
PCT/JP2008/072046
Other languages
French (fr)
Japanese (ja)
Inventor
Masahiro Toda
Ryo Ueda
Kozo Tsukada
Original Assignee
Keio University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Keio University filed Critical Keio University
Publication of WO2009072555A1 publication Critical patent/WO2009072555A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001152—Transcription factors, e.g. SOX or c-MYC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4615—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464452—Transcription factors, e.g. SOX or c-MYC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Provided are: a peptide comprising a sequence depicted in SEQ ID NO:1 or 2; a composition comprising the peptide; an antigen-presenting cell such as a dendritic cell, which has an antigen derived from the peptide presented thereon; and a T cell such as a cytotoxic T cell, which is activated with the antigen-presenting cell. Further provided is a method for treating cancer by administering the peptide comprising a sequence depicted in SEQ ID NO:1 or 2, the antigen-presenting cell or the cytotoxic T cell as a vaccine to a cancer patient.
PCT/JP2008/072046 2007-12-04 2008-12-04 Cancer vaccine WO2009072555A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-313856 2007-12-04
JP2007313856A JP5267969B2 (en) 2007-12-04 2007-12-04 Cancer vaccine

Publications (1)

Publication Number Publication Date
WO2009072555A1 true WO2009072555A1 (en) 2009-06-11

Family

ID=40717732

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/072046 WO2009072555A1 (en) 2007-12-04 2008-12-04 Cancer vaccine

Country Status (2)

Country Link
JP (1) JP5267969B2 (en)
WO (1) WO2009072555A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109952308A (en) * 2016-11-29 2019-06-28 深圳华大生命科学研究院 Polypeptide and its application
CN110167956A (en) * 2016-11-30 2019-08-23 深圳华大生命科学研究院 Polypeptide and its application
US11813318B2 (en) 2011-04-20 2023-11-14 University Of Washington Beta-2 microglobulin-deficient cells

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010285870A (en) 2009-06-09 2010-12-24 Denso Corp Instantaneous interruption detection apparatus for cylinder inner pressure sensor and control device of internal combustion engine
WO2012141201A1 (en) * 2011-04-11 2012-10-18 公立大学法人大阪市立大学 Peptide for cancer immunotherapy and method using same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003018629A1 (en) * 2001-08-23 2003-03-06 In2Gen Co., Ltd. Cage antigen
WO2006077941A1 (en) * 2005-01-19 2006-07-27 Keio University Cancer vaccine
JP2007246451A (en) * 2006-03-16 2007-09-27 Keio Gijuku Cancer vaccine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2794370B1 (en) * 1999-06-03 2003-10-17 Biovector Therapeutics POLYEPITOPIC PROTEIN FRAGMENTS, THEIR OBTAINMENT AND THEIR USES IN PARTICULAR IN VACCINATION

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003018629A1 (en) * 2001-08-23 2003-03-06 In2Gen Co., Ltd. Cage antigen
WO2006077941A1 (en) * 2005-01-19 2006-07-27 Keio University Cancer vaccine
JP2007246451A (en) * 2006-03-16 2007-09-27 Keio Gijuku Cancer vaccine

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
GOMI, S. ET AL.: "A cyclophilin B gene encodes antigenic epitopes recognized by HLA-A24- restricted and tumor-specific CTLs", J.IMMUNOL., vol. 163, 1999, pages 4994 - 5004 *
OARKER, K.C. ET AL.: "Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side- chains", J.IMMUNOL., vol. 152, 1994, pages 163 - 175 *
RYO UEDA ET AL.: "'Glioma Kogen SOX6 Peptide Vaccine ni yoru Tokuiteki Men'eki Ryoho no Kaihatsu'", SURG.FRONT., vol. 13, no. 2, 2006, pages 49 - 53 *
UEDA, R. ET AL.: "Identification of a human glioma antigen, SOX6, recognized by patients' sera", ONCOGENE, vol. 23, 2004, pages 1420 - 1427 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11813318B2 (en) 2011-04-20 2023-11-14 University Of Washington Beta-2 microglobulin-deficient cells
CN109952308A (en) * 2016-11-29 2019-06-28 深圳华大生命科学研究院 Polypeptide and its application
CN109952308B (en) * 2016-11-29 2022-09-23 武汉华大吉诺因生物科技有限公司 Polypeptide and application thereof
CN110167956A (en) * 2016-11-30 2019-08-23 深圳华大生命科学研究院 Polypeptide and its application
CN110167956B (en) * 2016-11-30 2023-04-07 深圳华大生命科学研究院 Polypeptide and application thereof

Also Published As

Publication number Publication date
JP2009137857A (en) 2009-06-25
JP5267969B2 (en) 2013-08-21

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