WO2009068749A3 - Apparatus and method for preparing sample analysis - Google Patents

Apparatus and method for preparing sample analysis Download PDF

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Publication number
WO2009068749A3
WO2009068749A3 PCT/FI2008/050691 FI2008050691W WO2009068749A3 WO 2009068749 A3 WO2009068749 A3 WO 2009068749A3 FI 2008050691 W FI2008050691 W FI 2008050691W WO 2009068749 A3 WO2009068749 A3 WO 2009068749A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
sample carrier
cutting
sample analysis
holder
Prior art date
Application number
PCT/FI2008/050691
Other languages
French (fr)
Other versions
WO2009068749A2 (en
Inventor
Vesa Erkkilae
Ari-Pekka Kitinoja
Jesse Mattila
Heimo Soitamo
Original Assignee
Wallac Oy
Vesa Erkkilae
Ari-Pekka Kitinoja
Jesse Mattila
Heimo Soitamo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallac Oy, Vesa Erkkilae, Ari-Pekka Kitinoja, Jesse Mattila, Heimo Soitamo filed Critical Wallac Oy
Publication of WO2009068749A2 publication Critical patent/WO2009068749A2/en
Publication of WO2009068749A3 publication Critical patent/WO2009068749A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873—Cutting or cleaving
    • G01N2001/2886—Laser cutting, e.g. tissue catapult

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Apparatus for handling sample carriers containing one or more biological samples impregnated therein. The apparatus comprises a holder (13) adapted to receive a sample carrier, and cutting tool (14) for cutting a sample-containing portion of the sample carrier supported by the holder. The cutting tool is adapted to direct to the sample carrier a localized cutting impact, such as laser beam or a water jet, which is moved on the surface of the sample carrier for detaching from the sample carrier said sample-containing portion. The invention offers a flexible, noiseless and dustless way of cutting samples for example for neonatal screening.
PCT/FI2008/050691 2007-11-30 2008-11-27 Apparatus and method for preparing sample analysis WO2009068749A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US99669207P 2007-11-30 2007-11-30
FI20075863 2007-11-30
FI20075863A FI20075863A0 (en) 2007-11-30 2007-11-30 Apparatus and method for preparing sample analysis
US60/996,692 2007-11-30

Publications (2)

Publication Number Publication Date
WO2009068749A2 WO2009068749A2 (en) 2009-06-04
WO2009068749A3 true WO2009068749A3 (en) 2009-07-16

Family

ID=38786792

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI2008/050691 WO2009068749A2 (en) 2007-11-30 2008-11-27 Apparatus and method for preparing sample analysis

Country Status (2)

Country Link
FI (1) FI20075863A0 (en)
WO (1) WO2009068749A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106999955A (en) * 2014-07-29 2017-08-01 约阿希姆·格斯特尔 For the component for the sample for preparing to be largely used to analysis method

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011002193B4 (en) * 2011-04-20 2018-11-29 Leica Biosystems Nussloch Gmbh Tissue specimen handling device
DE102011002194B4 (en) * 2011-04-20 2018-12-06 Leica Biosystems Nussloch Gmbh Tissue specimen handling device
TW201313288A (en) * 2011-09-23 2013-04-01 Nanoink Inc Accurate quantitation of biomarkers in samples
EP3404396B1 (en) 2017-05-17 2019-12-18 Roche Diagnostics GmbH System for processing a dried fluid sample substrate, and method therefor
EP3567362B1 (en) 2018-05-09 2022-03-30 Euroimmun Medizinische Labordiagnostika AG Method and device for segmenting and separating flat distributed samples using laser cutting

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583078A2 (en) * 1992-07-14 1994-02-16 Wallac Oy Method and apparatus for handling samples
DE19603996A1 (en) * 1996-02-05 1997-08-14 Bayer Ag Individual cells cut from polymer substrate foil
WO1998003628A1 (en) * 1996-07-19 1998-01-29 Bayer Aktiengesellschaft Device for separating micro objects
US20040077032A1 (en) * 2002-10-18 2004-04-22 Yung-Feng Nien Device and method for capturing biological tissues

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583078A2 (en) * 1992-07-14 1994-02-16 Wallac Oy Method and apparatus for handling samples
DE19603996A1 (en) * 1996-02-05 1997-08-14 Bayer Ag Individual cells cut from polymer substrate foil
WO1998003628A1 (en) * 1996-07-19 1998-01-29 Bayer Aktiengesellschaft Device for separating micro objects
US20040077032A1 (en) * 2002-10-18 2004-04-22 Yung-Feng Nien Device and method for capturing biological tissues

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SCHINDLER M: "A cut above the rest", THE BIOCHEMIST, 10-2002, pages 25 - 28, XP002485626, ISSN: 0954-982X, Retrieved from the Internet <URL:http://www.biochemist.org/bio/02405/0025/024050025.pdf> [retrieved on 20021001] *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106999955A (en) * 2014-07-29 2017-08-01 约阿希姆·格斯特尔 For the component for the sample for preparing to be largely used to analysis method

Also Published As

Publication number Publication date
WO2009068749A2 (en) 2009-06-04
FI20075863A0 (en) 2007-11-30

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