WO2009064897A3 - Détection de variations de séquences d'acides nucléiques dans l'acide nucléique circulant dans l'encéphalopathie spongiforme bovine - Google Patents

Détection de variations de séquences d'acides nucléiques dans l'acide nucléique circulant dans l'encéphalopathie spongiforme bovine Download PDF

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Publication number
WO2009064897A3
WO2009064897A3 PCT/US2008/083420 US2008083420W WO2009064897A3 WO 2009064897 A3 WO2009064897 A3 WO 2009064897A3 US 2008083420 W US2008083420 W US 2008083420W WO 2009064897 A3 WO2009064897 A3 WO 2009064897A3
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WO
WIPO (PCT)
Prior art keywords
nucleic acid
detection
spongiform encephalopathy
sequence variations
acid sequence
Prior art date
Application number
PCT/US2008/083420
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English (en)
Other versions
WO2009064897A2 (fr
Inventor
Ekkehard Schuetz
Julia Beck
Howard Urnovitz
Original Assignee
Chronix Biomedical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Chronix Biomedical filed Critical Chronix Biomedical
Publication of WO2009064897A2 publication Critical patent/WO2009064897A2/fr
Publication of WO2009064897A3 publication Critical patent/WO2009064897A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des procédés et des compositions permettant la détection d'une encéphalopathie spongiforme bovine transmissible (par exemple, ESB), basée sur la présence de polymorphismes associés à l'ESB dans des échantillons d'acides nucléiques dérivés d'échantillons acellulaires.
PCT/US2008/083420 2007-11-14 2008-11-13 Détection de variations de séquences d'acides nucléiques dans l'acide nucléique circulant dans l'encéphalopathie spongiforme bovine WO2009064897A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98806607P 2007-11-14 2007-11-14
US60/988,066 2007-11-14

Publications (2)

Publication Number Publication Date
WO2009064897A2 WO2009064897A2 (fr) 2009-05-22
WO2009064897A3 true WO2009064897A3 (fr) 2009-12-30

Family

ID=40639436

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/083420 WO2009064897A2 (fr) 2007-11-14 2008-11-13 Détection de variations de séquences d'acides nucléiques dans l'acide nucléique circulant dans l'encéphalopathie spongiforme bovine

Country Status (1)

Country Link
WO (1) WO2009064897A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9424392B2 (en) 2005-11-26 2016-08-23 Natera, Inc. System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US11332785B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US11408031B2 (en) 2010-05-18 2022-08-09 Natera, Inc. Methods for non-invasive prenatal paternity testing
US11339429B2 (en) 2010-05-18 2022-05-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
CA2798758C (fr) 2010-05-18 2019-05-07 Natera, Inc. Procedes de classification de ploidie prenatale non invasive
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US11332793B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for simultaneous amplification of target loci
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11326208B2 (en) 2010-05-18 2022-05-10 Natera, Inc. Methods for nested PCR amplification of cell-free DNA
AU2011358564B9 (en) 2011-02-09 2017-07-13 Natera, Inc Methods for non-invasive prenatal ploidy calling
CN106460070B (zh) 2014-04-21 2021-10-08 纳特拉公司 检测染色体片段中的突变和倍性
US11479812B2 (en) 2015-05-11 2022-10-25 Natera, Inc. Methods and compositions for determining ploidy
WO2018067517A1 (fr) 2016-10-04 2018-04-12 Natera, Inc. Procédés pour caractériser une variation de nombre de copies à l'aide d'un séquençage de ligature de proximité
US10011870B2 (en) 2016-12-07 2018-07-03 Natera, Inc. Compositions and methods for identifying nucleic acid molecules
US11525159B2 (en) 2018-07-03 2022-12-13 Natera, Inc. Methods for detection of donor-derived cell-free DNA
KR102241471B1 (ko) * 2019-10-31 2021-04-15 전북대학교산학협력단 광우병 연관성 체세포 돌연변이 검출용 프라이머

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040161758A1 (en) * 2000-03-06 2004-08-19 Scott Seiwert Detection of infectious prion proteins and associated antibodies using nucleic acid sensor molecules
US20050009031A1 (en) * 2001-10-25 2005-01-13 Becker Kenneth David Genes and polymorphisms on chromosome 10 associated with Alzheimer's disease and other neurodegenerative diseases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040161758A1 (en) * 2000-03-06 2004-08-19 Scott Seiwert Detection of infectious prion proteins and associated antibodies using nucleic acid sensor molecules
US20050009031A1 (en) * 2001-10-25 2005-01-13 Becker Kenneth David Genes and polymorphisms on chromosome 10 associated with Alzheimer's disease and other neurodegenerative diseases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NAKAMURA ET AL.: "Novel single nucleotide polymorphisms in the specific protein 1 binding site of the bovine PRNP promoter in Japanese black cattle : Impairment of its promoter activity.", INTERVIROLOGY, vol. 50, 2 February 2007 (2007-02-02), pages 190 - 196 *

Also Published As

Publication number Publication date
WO2009064897A2 (fr) 2009-05-22

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