WO2009063029A3 - Substituted amides, manufacturing and use thereof as medicaments - Google Patents

Substituted amides, manufacturing and use thereof as medicaments Download PDF

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Publication number
WO2009063029A3
WO2009063029A3 PCT/EP2008/065511 EP2008065511W WO2009063029A3 WO 2009063029 A3 WO2009063029 A3 WO 2009063029A3 EP 2008065511 W EP2008065511 W EP 2008065511W WO 2009063029 A3 WO2009063029 A3 WO 2009063029A3
Authority
WO
WIPO (PCT)
Prior art keywords
substituted amides
medicaments
manufacturing
salts
tautomers
Prior art date
Application number
PCT/EP2008/065511
Other languages
French (fr)
Other versions
WO2009063029A2 (en
Inventor
Roland Pfau
Georg Dahmann
Kai Gerlach
Herbert Nar
Henning Priepke
Annette Schuler-Metz
Wolfgang Wienen
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of WO2009063029A2 publication Critical patent/WO2009063029A2/en
Publication of WO2009063029A3 publication Critical patent/WO2009063029A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to new substituted amides of general formula (I) wherein D, L, B, R4 und R5 are defined as in the specification, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties.
PCT/EP2008/065511 2007-11-16 2008-11-14 Substituted amides, manufacturing and use thereof as medicaments WO2009063029A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07120841.7 2007-11-16
EP07120841 2007-11-16

Publications (2)

Publication Number Publication Date
WO2009063029A2 WO2009063029A2 (en) 2009-05-22
WO2009063029A3 true WO2009063029A3 (en) 2009-12-23

Family

ID=40578067

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/065511 WO2009063029A2 (en) 2007-11-16 2008-11-14 Substituted amides, manufacturing and use thereof as medicaments

Country Status (1)

Country Link
WO (1) WO2009063029A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007009963A1 (en) * 2005-07-19 2007-01-25 Boehringer Ingelheim International Gmbh Substituted amides, their preparation and their use as pharmaceuticals
WO2007025940A1 (en) * 2005-08-29 2007-03-08 Boehringer Ingelheim International Gmbh Substituted biaryls and their use as factor xa inhibitors
US20070185092A1 (en) * 2004-06-18 2007-08-09 Millennium Pharmaceuticals, Inc. FACTOR Xa INHIBITORS
WO2007131179A1 (en) * 2006-05-05 2007-11-15 Millennium Pharmaceuticals, Inc. Factor xa inhibitors

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070185092A1 (en) * 2004-06-18 2007-08-09 Millennium Pharmaceuticals, Inc. FACTOR Xa INHIBITORS
WO2007009963A1 (en) * 2005-07-19 2007-01-25 Boehringer Ingelheim International Gmbh Substituted amides, their preparation and their use as pharmaceuticals
WO2007025940A1 (en) * 2005-08-29 2007-03-08 Boehringer Ingelheim International Gmbh Substituted biaryls and their use as factor xa inhibitors
WO2007131179A1 (en) * 2006-05-05 2007-11-15 Millennium Pharmaceuticals, Inc. Factor xa inhibitors

Also Published As

Publication number Publication date
WO2009063029A2 (en) 2009-05-22

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