WO2009060620A1 - ポリペプチドの製造方法 - Google Patents

ポリペプチドの製造方法 Download PDF

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Publication number
WO2009060620A1
WO2009060620A1 PCT/JP2008/003226 JP2008003226W WO2009060620A1 WO 2009060620 A1 WO2009060620 A1 WO 2009060620A1 JP 2008003226 W JP2008003226 W JP 2008003226W WO 2009060620 A1 WO2009060620 A1 WO 2009060620A1
Authority
WO
WIPO (PCT)
Prior art keywords
producing
amino acid
polypeptide
producing polypeptide
disclosed
Prior art date
Application number
PCT/JP2008/003226
Other languages
English (en)
French (fr)
Inventor
Kentaro Nakamura
Shouji Ooya
Tetsuo Hiratou
Original Assignee
Fujifilm Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corporation filed Critical Fujifilm Corporation
Publication of WO2009060620A1 publication Critical patent/WO2009060620A1/ja

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Peptides Or Proteins (AREA)
  • Polyamides (AREA)

Abstract

　本発明の目的は、長鎖かつ高分子量のポリペプチドを有機合成化学的な手法で製造する方法を提供することである。本発明によれば、アミノ酸及び／又はアミノ酸２～１０残基からなるペプチドを有機フッ素化合物の存在下で重合させることを含む、ポリペプチドの製造方法が提供される。  
PCT/JP2008/003226 2007-11-08 2008-11-07 ポリペプチドの製造方法 WO2009060620A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007290551 2007-11-08
JP2007-290551 2007-11-08

Publications (1)

Publication Number Publication Date
WO2009060620A1 true WO2009060620A1 (ja) 2009-05-14

Family

ID=40625527

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/003226 WO2009060620A1 (ja) 2007-11-08 2008-11-07 ポリペプチドの製造方法

Country Status (1)

Country Link
WO (1) WO2009060620A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013524817A (ja) * 2010-04-23 2013-06-20 ライフ テクノロジーズ コーポレーション 小ペプチドを含む細胞培養培地

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6461497A (en) * 1987-08-31 1989-03-08 Central Glass Co Ltd Mixed solvent
WO2007043615A1 (ja) * 2005-10-14 2007-04-19 Osaka University ペプチドエステル試薬、およびそのライゲーションまたはチオエステル化合物の製造のための使用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6461497A (en) * 1987-08-31 1989-03-08 Central Glass Co Ltd Mixed solvent
WO2007043615A1 (ja) * 2005-10-14 2007-04-19 Osaka University ペプチドエステル試薬、およびそのライゲーションまたはチオエステル化合物の製造のための使用

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"The Japanese Biochemical Society, Shin Seikagaku Jikken Koza 1 Tanpakushitsu VI -Gosei Oyobi Hatsugen", 15 June 1992, KABUSHIKI KAISHA TOKYO KAGAKU DOJIN, pages: 16 - 17 *
FIELDS GB. ET AL.: "Solvation effects in solid-phase peptide synthesis", J. AM. CHEM. SOC., vol. 113, no. 11, 1991, pages 4202 - 4207 *
GOWDA DC. ET AL.: "Synthesis and characterization of the human elastin W4 sequence", INT. J. PEPT. PROTEIN RES., vol. 46, no. 6, 1995, pages 453 - 463 *
IZUMIYA N. ET AL.: "Peptide Gosei no Kiso to Jikken", 20 January 1985, MARUZEN CO., LTD., pages: 236 - 237 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013524817A (ja) * 2010-04-23 2013-06-20 ライフ テクノロジーズ コーポレーション 小ペプチドを含む細胞培養培地
JP2017006127A (ja) * 2010-04-23 2017-01-12 ライフ テクノロジーズ コーポレーション 小ペプチドを含む細胞培養培地
JP2018113996A (ja) * 2010-04-23 2018-07-26 ライフ テクノロジーズ コーポレーション 小ペプチドを含む細胞培養培地
JP2020137529A (ja) * 2010-04-23 2020-09-03 ライフ テクノロジーズ コーポレーション 小ペプチドを含む細胞培養培地
US10793827B2 (en) 2010-04-23 2020-10-06 Life Technologies Corporation Cell culture medium comprising small peptides
US11365389B2 (en) 2010-04-23 2022-06-21 Life Technologies Corporation Cell culture medium comprising small peptides
JP7200180B2 (ja) 2010-04-23 2023-01-06 ライフ テクノロジーズ コーポレーション 小ペプチドを含む細胞培養培地

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