WO2009044009A3 - Utilisation du 4-azacholest-4-ène n-oxide ou de ses dérivés comme antioxydants - Google Patents

Utilisation du 4-azacholest-4-ène n-oxide ou de ses dérivés comme antioxydants Download PDF

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Publication number
WO2009044009A3
WO2009044009A3 PCT/FR2008/001100 FR2008001100W WO2009044009A3 WO 2009044009 A3 WO2009044009 A3 WO 2009044009A3 FR 2008001100 W FR2008001100 W FR 2008001100W WO 2009044009 A3 WO2009044009 A3 WO 2009044009A3
Authority
WO
WIPO (PCT)
Prior art keywords
azacholest
ene
antioxidants
derivatives
oxide
Prior art date
Application number
PCT/FR2008/001100
Other languages
English (en)
Other versions
WO2009044009A2 (fr
Inventor
Rebecca Pruss
Cyrille Drouot
Original Assignee
Trophos
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trophos filed Critical Trophos
Publication of WO2009044009A2 publication Critical patent/WO2009044009A2/fr
Publication of WO2009044009A3 publication Critical patent/WO2009044009A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

L'invention concerne l'utilisation du 4-azacholest-4-ène N-oxide ou d'au moins un de ses dérivés comme antioxydants dans les domaines cosmétiques et alimentaires, et comme conservateurs antioxydant utilisables notamment dans des produits cosmétiques, alimentaires, et pharmaceutiques.
PCT/FR2008/001100 2007-07-25 2008-07-24 Utilisation du 4-azacholest-4-ène n-oxide ou de ses dérivés comme antioxydants WO2009044009A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0705427 2007-07-25
FR0705427A FR2919181A1 (fr) 2007-07-25 2007-07-25 Utilisation du 4-azacholest-4-ene n-oxide ou de ses derives comme antioxydants

Publications (2)

Publication Number Publication Date
WO2009044009A2 WO2009044009A2 (fr) 2009-04-09
WO2009044009A3 true WO2009044009A3 (fr) 2009-11-05

Family

ID=39156847

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/001100 WO2009044009A2 (fr) 2007-07-25 2008-07-24 Utilisation du 4-azacholest-4-ène n-oxide ou de ses dérivés comme antioxydants

Country Status (2)

Country Link
FR (1) FR2919181A1 (fr)
WO (1) WO2009044009A2 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527807A (en) * 1992-05-20 1996-06-18 Merck & Co., Inc. 7β-substituted-4-aza-5α-cholestan-3-ones as 5α reductase inhibitors useful in the prevention and treatment of hyperandrogenetic disorders
US5922335A (en) * 1995-05-15 1999-07-13 Avon Products, Inc. Uses for ascorbyl-phosphoryl-cholesterol in topical compositions
EP1295600A2 (fr) * 2001-09-21 2003-03-26 Dr. Kade Pharmazeutische Fabrik GmbH Médicament à base de gestagenes à application dermique
FR2907783A1 (fr) * 2006-10-30 2008-05-02 Trophos Sa Nouveaux composes chimiques, leurs procedes de synthese et leur utilisation a titre de medicament, particulierement a titre de medicament cytoprotecteur, neuroprotecteur ou cardioprotecteur

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527807A (en) * 1992-05-20 1996-06-18 Merck & Co., Inc. 7β-substituted-4-aza-5α-cholestan-3-ones as 5α reductase inhibitors useful in the prevention and treatment of hyperandrogenetic disorders
US5922335A (en) * 1995-05-15 1999-07-13 Avon Products, Inc. Uses for ascorbyl-phosphoryl-cholesterol in topical compositions
EP1295600A2 (fr) * 2001-09-21 2003-03-26 Dr. Kade Pharmazeutische Fabrik GmbH Médicament à base de gestagenes à application dermique
FR2907783A1 (fr) * 2006-10-30 2008-05-02 Trophos Sa Nouveaux composes chimiques, leurs procedes de synthese et leur utilisation a titre de medicament, particulierement a titre de medicament cytoprotecteur, neuroprotecteur ou cardioprotecteur

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BURBIEL J ET AL: "Azasteroids as antifungals", September 2003, STEROIDS, BUTTERWORTH-HEINEMANN, STONEHAM, MA, US, PAGE(S) 587-594, ISSN: 0039-128X, XP004453284 *
KRSTIC ET AL: "Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities", STEROIDS, ELSEVIER SCIENCE PUBLISHERS, NEW YORK, NY, US, vol. 72, no. 5, 21 April 2007 (2007-04-21), pages 406 - 414, XP022041669, ISSN: 0039-128X *
PRADHAN ET AL: "Unusual Reactions of Steroidal and Non-Steroidal 1,5-Dioximes. Stereochemistry and Mechanism of Formation of N-Hydroxy-Piperidine Analogues", 1989, HETEROCYCLES, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, PAGE(S) 813-839, ISSN: 0385-5414, XP009083854 *

Also Published As

Publication number Publication date
WO2009044009A2 (fr) 2009-04-09
FR2919181A1 (fr) 2009-01-30

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