WO2009039724A1 - Equipement thérapeutique à aiguille à partir d'informations biologiques pour un traitement d'acupuncture - Google Patents

Equipement thérapeutique à aiguille à partir d'informations biologiques pour un traitement d'acupuncture Download PDF

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Publication number
WO2009039724A1
WO2009039724A1 PCT/CN2008/001390 CN2008001390W WO2009039724A1 WO 2009039724 A1 WO2009039724 A1 WO 2009039724A1 CN 2008001390 W CN2008001390 W CN 2008001390W WO 2009039724 A1 WO2009039724 A1 WO 2009039724A1
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WIPO (PCT)
Prior art keywords
acupuncture
manipulation
biological information
diarrhea
electrode
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PCT/CN2008/001390
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English (en)
Chinese (zh)
Inventor
Yang Cao
Bing Zhu
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Suzhou Medical Appliance Factory
Institute Of Acupuncture And Moxibustion China Academy Of Chinese Medical Science
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Application filed by Suzhou Medical Appliance Factory, Institute Of Acupuncture And Moxibustion China Academy Of Chinese Medical Science filed Critical Suzhou Medical Appliance Factory
Publication of WO2009039724A1 publication Critical patent/WO2009039724A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/08—Devices for applying needles to such points, i.e. for acupuncture ; Acupuncture needles or accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes

Definitions

  • the invention relates to an acupuncture instrument for medical and health care (also called “electric acupuncture instrument” or “electro-acupuncture instrument”).
  • the acupuncture device is triggered by a famous acupuncture method, and the nerve reaction peak signal encoded by all the afferent information generated by acupoint stimulation is collected from the living body as an electric pulse signal source. It can accurately express and quantify the bioelectrical information caused by various acupuncture acupuncture methods, and further improve the clinical efficacy of the acupuncture instrument.
  • Percutaneous electrical nerve stimulation is a method of electrotherapy that treats pain by introducing specific low-frequency pulse currents into the body through the skin. This is an electrotherapy that emerged in the 1970s. It has received good results in pain relief and has been proven to have a definite therapeutic effect on more than 20 neurological disorders. Therefore, it has been widely used in clinical practice (especially in Europe and America) and has been gradually used by both domestic and foreign.
  • acupuncture electroacupuncture This kind of therapy will take acupuncture into the acupoints and get a gas.
  • the acupuncture needles will be connected to the micro-currents of the human bioelectricity, and the combination of needle and electricity will be used to prevent diseases.
  • the advantage is that it can replace the person for a longer period of time and save manpower.
  • electroacupuncture instruments began in the 70s and 80s of the last century.
  • the buzzer type electro-acupuncture instrument is a kind of electric bell oscillation principle, which converts direct current into pulse current and finally acts on the human body.
  • This pulse current waveform is narrow, such as a needle tip, and is asymmetrical. Due to the high power consumption and noise, it is rarely used now.
  • the buck-type AC electro-acupuncture instrument is a kind of general-purpose AC power supply that reduces the voltage to 25V or less through a transformer, and then regulates the output through a resistor and a potentiometer to obtain an appropriate stimulation intensity. Since the frequency is not adjustable, it is rarely used now.
  • Audio Oscillating Electro-Needle Instrument is a kind of sine wave electro-acupuncture instrument with adjustable frequency in the range of 20 ⁇ 200Hz. Although the frequency and output intensity are adjustable, the waveform is simple and the effect is poor, so it is rarely used at present.
  • transistor noise type electro-acupuncture instrument The power supply of this electro-acupuncture instrument is DC 6V, the noise frequency is 15000 ⁇ 20000Hz, the modulation frequency is 3 ⁇ 30 Hz, and the output voltage is 0 ⁇ 50V. It is mainly used for acupuncture and analgesic treatment, etc. ⁇ Easy to cause an electrochemical reaction to acupuncture needles during treatment, causing an accident. 5.
  • Acoustic electro-acupuncture instrument ie electroacoustic needle, is a kind of sound source generated by the sound wave generator, such as music, drama, song, radio and other sound waves input to the electro-acupuncture instrument, output through the wire and acupuncture needle pierced into the acupuncture point.
  • Pulse electro-acupuncture instrument is the most widely used electro-acupuncture instrument at home and abroad. It uses intermittent oscillation as a pulse generator, and the variable resistor changes the time constant of the circuit to control the pulse frequency. A plurality of sets of isolated output windings are wound around the oscillating transformer, and the output of the windings is divided by a potentiometer and output.
  • a square wave is input from a multivibrator, a sparse wave and a discontinuous wave and a pulse wave pattern can be obtained.
  • the frequencies of the two waveforms are not adjustable, and the amplitude wave generated by the square wave can modulate its amplitude to obtain pulse waveforms such as undulating waves and sawtooth waves.
  • electroacupuncture and manual needle are two kinds of stimuli.
  • the electroacupuncture relies on the action of applied current (voltage) to excite the acupoint tissue, which is easy to produce effect fatigue (asymmetric attenuation of afferent nerve release).
  • the hand movement method is to stimulate the acupoint tissue by means of mechanical actions such as lifting and twisting. Therefore, the needle feel of the electroacupuncture and the hand-held needle is different from that of the afferent nerve fiber.
  • the former is mainly based on hemp, mainly through the crude fiber-based afferent center, and the latter is mainly based on soreness.
  • the m-based fine fibers are introduced into the center.
  • the invention provides a biological information acupuncture device triggered by acupuncture manipulation, the purpose of which is to explore the afferent neural information coding reaction caused by different manipulations of acupuncture, and design and develop various acupuncture methods which can accurately express and quantify.
  • the biological information acupuncture instrument for information decoding is combined with the acupuncture method and the acupuncture treatment by the principle of biological information feedback therapy, thereby improving the clinical efficacy of the acupuncture instrument.
  • the technical solution adopted by the present invention is: a biological information acupuncture device triggered by acupuncture and acupuncture manipulation, the electric pulse sequence of the acupuncture device is stimulated by acupuncture manipulation method At position 200, a set of afferent coding response neuron spike signals containing biological information elicited on the spinal cord broad dynamic neurons is used as an electrical pulse signal source and amplified to the electrodes of the acupuncture instrument.
  • the "animal” generally refers to a living body that is highly compatible with human structures and functions and genomes.
  • the acupuncture method may be a double-handed method, and at least one of the following six commonly used ones: (1), flattening and diarrhea; (2), twirling and replenishing; (3), lifting Replenishing diarrhea; (4), Xu disease replenishing diarrhea; (5), Qinglong swaying tail; (6), the turtle to explore the point.
  • the acupuncture method may also be a single-handed method, and at least one of the following six commonly used ones: (1), twirling; (2), shaking method; (3), scraping method; 4), law; (5), bomb method;
  • the electrode of the acupuncture instrument is a millineedle electrode or a skin electrode.
  • the needle electrode refers to a metal needle that penetrates into human tissue, such as an acupuncture needle
  • the skin electrode refers to an electrode attached to the surface of a human skin.
  • the principle of the invention 6 kinds of methods, 6 kinds of single techniques) respectively stimulate the acupuncture points of the animal, a set of incoming information encoded on the spinal cord of the broad-powered neurons encoded electrical signals as an electrical pulse signal source, amplified output to The electrode of the acupuncture instrument.
  • the electric pulse sequence is a set of peak potential pulse sequences, which can accurately express and quantify the biological information caused by various acupuncture acupuncture methods, and apply the spike signal sequence containing biological information to the needle according to the principle of bioinformation feedback therapy.
  • the therapeutic apparatus can improve the clinical efficacy of the acupuncture apparatus.
  • the present invention has the following advantages and effects compared with the prior art:
  • the invention is undoubtedly a major innovation in the field of traditional Chinese medicine acupuncture clinical and scientific research, promoting the common development of acupuncture and bioinformatics, and promoting the standardization process of acupuncture and moxibustion of Chinese medicine, and promoting this intangible culture.
  • Acupuncture is a kind of stimulation therapy on the body surface.
  • Acupuncture information is transmitted to the central nervous system mainly through afferent nerves. It is a group of groups in the combination of temporal and spatial sequences of neural information in the form of the brain to participate in the integration and regulation of the body's functional activities. Understanding the afferent information coding of acupuncture can not only quantify the role and mechanism of acupuncture, but also promote the understanding of the processing of neural information. Combining the study of acupuncture with the conduction and processing of neural information coding forms, this original research will certainly promote the commonality of the two sciences.
  • the invention can clone acupuncture techniques with unique characteristics of acupuncture and moxibustion to widely absorb various kinds of transmissions.
  • the biological information spike potential pulse of the invention is not an applied current, but an organism's own neural afferent information coding pulse, which conforms to the principle of biofeedback therapy, and the bioinformation group coding is not a single pulse issued by a simple electrical pulse signal generator, tissue susceptor It is not easy to adapt, so as to maintain a continuous and variable stimulation state, thereby further improving the clinical efficacy of the acupuncture instrument.
  • Simple and constant pulse stimulation is easy to produce rapid-slow adaptation to the body's sensory device. Under the condition of constant stimulation intensity and frequency, the afferent response of the sensor will adapt quickly and gradually decrease.
  • the group codes generated by the 12 commonly used acupuncture manipulations of the present invention have their own characteristics, and the adaptation occurs in the process of the whole needle movement without the electroacupuncture stimulation (the afferent nerve is progressively attenuated). It has been observed in experimental observation that different acupuncture methods have different effects on electrical stimulation of different body surface pains and inhibition of chronic inflammatory pain and visceral pain. Therefore, clinicians can choose different acupuncture methods according to the condition to adapt to individualized treatment of acupuncture.
  • 1A is a time series of a neural peak potential signal collected from the dorsal horn of the spine by a flat-filled acupuncture acupuncture method, wherein the abscissa indicates time and the unit is second; and the ordinate indicates the amplitude of the peak potential of the neuron, and the unit is microvolt. .
  • Figure 1B is a phase space reconstructed attractor map corresponding to the flattening and diarrhea method, wherein the abscissa indicates the action potential amplitude - a point of calculation; the ordinate indicates the action potential amplitude - another point of calculation.
  • 1C is a Lyapunov exponent map corresponding to the flattening method, wherein the abscissa indicates the number of points of calculation; the ordinate indicates the dimensionless, encoded contrast value of the neuron response.
  • 2A is a time series of a neural peak potential signal collected from the dorsal horn of the spine using a sputum acupuncture acupuncture method, wherein the abscissa indicates time and the unit is second; and the ordinate indicates the amplitude of the peak potential of the neuron, and the unit is microvolt. .
  • Fig. 2B is a phase space reconstructed attractor diagram corresponding to the ⁇ ⁇ ⁇ ⁇ , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,
  • Figure 2C is a Lyapunov exponent map corresponding to the ⁇ ⁇ ⁇ , , method, where the abscissa indicates the calculated number of points of time; the ordinate indicates the dimensionless, encoded comparison value of the neuron response.
  • Figure 3A is a time series of a neural peak potential signal collected from the dorsal horn of the spine by a lifting and puncturing acupuncture method, wherein the abscissa indicates time and the unit is second; the ordinate indicates the amplitude of the peak potential of the neuron, and the unit is microvolt. .
  • Figure 3B is a phase space reconstructed attractor map corresponding to the interpolation and occlusion technique, wherein the abscissa represents the action potential amplitude - a point of calculation; the ordinate represents the action potential amplitude - another point of calculation.
  • Figure 3C is a Lyapimov index map corresponding to the method of extracting and diarrhea, wherein the abscissa table The calculated number of points for the time; the ordinate indicates the dimensionless, encoded comparison of the neuronal response.
  • Figure 4A is a time series of a neural peak potential signal collected from the dorsal horn of the spine using a Xuji diarrhea acupuncture manipulation method, wherein the abscissa indicates time and the unit is seconds; the ordinate indicates the amplitude of the peak potential of the neuron, and the unit is microvolt. .
  • Fig. 4B is a phase space reconstruction attractor diagram corresponding to the Xu disease replenishment technique, wherein the abscissa indicates the action potential amplitude-calculated point; the ordinate indicates the action potential amplitude-calculation another point.
  • Fig. 4C is a Lyapimov index map corresponding to the Xu disease replenishment technique, wherein the abscissa indicates the calculation point of time; the ordinate indicates the dimensionless, encoded comparison value of the neuron reaction.
  • Fig. 5A is a time series of a neural peak potential signal collected from the dorsal horn of the spine by a needle-punching technique of a dragon, wherein the abscissa indicates time and the unit is second; and the ordinate indicates the amplitude of the peak potential of the neuron, and the unit is microvolt. .
  • Figure 5B is a phase space reconstructed attractor map corresponding to the Qinglong swing tail manipulating method, wherein the abscissa represents the action potential amplitude - the calculated point; the ordinate represents the action potential amplitude - another point of the calculation.
  • Figure 5C is a Lyapunov exponent map corresponding to the Qinglong pendulum technique, where the abscissa indicates the calculated number of points of time; the ordinate indicates the dimensionless, encoded comparison value of the neuron response.
  • Figure 6A is a time series of a neural peak potential signal collected from the dorsal horn of the spine using acupuncture acupuncture, wherein the abscissa indicates time and the unit is second; the ordinate indicates the amplitude of the peak potential of the neuron, and the unit is micro Volt.
  • Fig. 6B is a phase space reconstructed attractor map corresponding to the method of the turtle's acupoint, wherein the abscissa indicates the amplitude of the action potential - a point of calculation; the ordinate indicates the amplitude of the action potential - another point of calculation.
  • Figure 6C is a Lyapunov exponent map corresponding to the method of the turtle's acupoint, where the abscissa indicates the calculated number of points of time; the ordinate indicates the dimensionless, encoded contrast value of the neuron response.
  • a biological information acupuncture device triggered by acupuncture and acupuncture manipulation, the electric pulse sequence of the acupuncture therapy device is used by acupuncturists of traditional Chinese medicine to use six common acupuncture techniques and six single-handed techniques to stimulate the acupuncture points of the animal respectively.
  • a set of groups containing bioinformatics on the spine-wide dynamic neurons encodes a reactive electrical signal that encodes the electrical signal as an electrical pulse source that is amplified and output to the electrodes of the acupuncture instrument.
  • the six kinds of compound acupuncture methods commonly used in traditional Chinese medicine acupuncture are: (1), Pingbu Pingxue; (2), phlegm and diarrhea; (3), lifting and diarrhea; (4), Xu disease and diarrhea (5), Qinglong swing tail; (6), the turtle to explore the point.
  • the six single-handed techniques commonly used in traditional Chinese medicine acupuncture are: (1), twirling; (2), shaking method; (3), scraping method; (4), tremor method; (5), bomb method; 6), flying method.
  • What needs to be emphasized here is the Chinese medicine needle
  • the acupuncture method commonly used in moxibustion can select one or two or more of the above 12 methods, and can also screen and combine in a larger range of Chinese acupuncture and acupuncture methods.
  • the electrode of the acupuncture instrument of the embodiment may be a millineedle electrode or a drop electrode.
  • the needle electrode is generally a pointer moxibustion needle
  • the skin electrode refers to a patch electrode attached to the surface of a human skin.
  • the electric pulse signal source of the acupuncture instrument can be realized by a database method, that is, a group of groups containing biometric information corresponding to various techniques is encoded and the reaction electric signal is digitized and then solidified and stored in a memory, when the corresponding acupuncture is selected.
  • the program calls the corresponding data in the memory, restores the electrical pulse signal, and then the electrical pulse signal is amplified by the amplification circuit and output to the electrode of the acupuncture instrument.
  • circuitry and control of the acupuncture instrument prior art can be used and will be known to those of ordinary skill in the art and will not be described in detail herein.
  • the nerve spike potential pulse sequence is a set of afferent information encoding reaction in the "Zusanli" point of the animal, which is stimulated by the flat-filled acupuncture acupuncture method, and the afferent information coding reaction is 31.
  • Fig. 1A is a time sequence of an electrical signal collected from the dorsal horn of the spinal cord by an embodiment of the acral acupuncture acupuncture technique.
  • Fig. 1B is a phase space reconstruction attractor diagram corresponding to the embodiment of the flattening and diarrhea method.
  • Fig. 1C is a Lyapunov exponent diagram corresponding to the embodiment of the flattening and diarrhea method "i ⁇ .
  • the nerve spike potential pulse sequence is a set of afferent information coding reaction triggered by the sputum acupuncture and acupuncture manipulation method to stimulate the animal "Zusanli" point on the ridged broad-powered neurons.
  • the incoming information encodes a response.
  • a group of peak-potential pulse sequences with chaotic characteristics, the attractor is specific, and the Lyapimov index is 1.7333.
  • Fig. 2A is a time sequence of an electrical signal collected from the dorsal horn of the spine by a sputum acupuncture method of the embodiment.
  • FIG. Fig. 2C is a Lyapimov index map corresponding to the embodiment of the ⁇ ⁇ ⁇ ⁇ ⁇ .
  • the nerve spike potential pulse sequence is a set of afferent information coding reaction triggered by the spinal cord and the dynamic nerve neurons stimulated by the acupuncture and acupuncture manipulation method of the animal "Zusanli".
  • the incoming information encodes a response.
  • the Lyapiinov index is 1.7676.
  • FIG. 3A is a time sequence of an electrical signal collected from the dorsal horn of the spinal cord by an embodiment of the acne acupuncture acupuncture.
  • FIG. 3B is a phase space reconstruction attractor diagram corresponding to the interpolation and occlusion method of the embodiment.
  • FIG. 3C is a Lyapunov exponent map corresponding to the interpolation method of the embodiment.
  • the nerve spike potential pulse sequence is a set of afferent information coding reaction initiated by the Xujiu diarrhea acupuncture manipulation method to stimulate the animal "Zusanli" acupoint on the spinal cord broad-dynamic neuron, and the incoming information encodes a response.
  • Fig. 4A is a time sequence of an electrical signal collected from the dorsal horn of the spinal cord by the Xu diarrhea acupuncture manipulation method of the embodiment.
  • Fig. 4B is a phase space reconstruction attractor map corresponding to the Xu disease replenishing method of the embodiment.
  • Fig. 4C is a Lyapimov index map corresponding to the Xu disease replenishing method of the embodiment.
  • the nerve spike potential pulse sequence is a set of afferent information coding reactions triggered by the Qinglong pendulum acupuncture manipulation method to stimulate the animal "Zusanli", which is triggered by a group of afferent information coding responses.
  • a spike sequence with chaotic characteristics, the attractor is specific, and the Lyapimov index is 1.5934.
  • Fig. 5A is a time sequence of an electrical signal collected from the spinal dorsal horn of the embodiment.
  • Fig. 5B is a phase space reconstruction attractor diagram corresponding to the Qinglong swing tail technique of the embodiment.
  • Fig. 5C is a Lyapunov exponent map corresponding to the Qinglong swing tail technique of the embodiment.
  • the nerve spike potential pulse sequence is a set of afferent information coding reaction triggered by the acupuncture manipulation of the arachnid to the animal "Zusanli", which is triggered by a broad-dynamic neuron of the spinal cord.
  • the incoming information encodes a response.
  • a group of peak potential pulse sequences with chaotic characteristics, the attractor is specific, and the Lyapunov exponent is 1.7536.
  • Fig. 6A is a time sequence of electrical signals collected from the dorsal horn of the spinal cord by the acupuncture manipulation method of the turtle.
  • Fig. 6B is a phase space reconstruction attractor diagram corresponding to the method of the turtle acupoints of the embodiment.
  • Fig. 6C is a Lyapunov exponent map corresponding to the method of the turtle acupoint in the embodiment.
  • Lyapunov exponent is used to measure the convergence rate and divergence rate of the orbit.
  • a set of Lyap unov exponents called Lyapunov exponent spectrum, can be calculated, where each exponent corresponds to an orbital convergence rate or divergence rate in a particular direction.
  • the number of Lyapunov exponents is equal to the dimension of the phase space.
  • a chaotic system has one or more positive values in its Lyapunov exponent borrowing. The calculation of the Lyapunov exponent is performed in the phase space, so to calculate the time series, the delay coordinate is used.
  • the method of phase space reconstruction Sampling a continuous signal at equal intervals produces an M-dimensional time series that forms its own trajectory in the M-dimensional phase space, which is phase space reconstruction. This allows you to calculate the Lyap unov finger in the reconstructed phase space.
  • the Lyapuiiov index describes how sensitive the chaotic system is to initial values.
  • the nonlinear dynamic analysis of the incoming signal encoding reaction signal obtained by the set is firstly phase space reconstruction.
  • the reconstruction parameters are determined: delay time T and embedding dimension ni, the mutual information function is used to determine The delay time T; the Cao method is combined to determine the embedding dimension m, and the reconstructed attractor of each method is obtained.
  • the attractors corresponding to the various methods are singular, qualitatively indicating that these signals are chaotic time series.
  • the method of calculating the Lyapimov exponent of the biological system is used to quantitatively characterize the degree of chaos of these time series.
  • T is called the delay time
  • m is called the Embedding dimension
  • phase space reconstruction process There are two very important parameters in the phase space reconstruction process: delay time T, embedding dimension m.
  • the mutual information function is used to determine the delay time T
  • the Cao method is used to determine the embedding dimension m.
  • the delay ⁇ is a positive integer, and the actual delay time is the product of the time interval ⁇ t and ⁇ . If the delay time T is too small, the state vectors will be very close, and each state vector carries a large amount of redundant information. When T ⁇ 0, all state vectors will be indistinguishable under noise ⁇ ⁇ , causing the reconstructed attractor to be squeezed near the main diagonal of the phase space. Conversely, if the delay time is too large, it will cause the m-dimensional coordinates to be basically irrelevant, making even simple graphics extremely complicated to look at. The task of choosing the delay time is to avoid these two extremes, so that the delay coordinates are maximized and the dynamic properties are maintained.
  • the more common use is the mutual information function.
  • the time corresponding to a local minimum is determined as the delay time T. Since the mutual information function is a measure of the general random correlation between two random variables, it is a reasonable method to use the mutual information function to determine the delay time.
  • the embedding dimension m should satisfy: m ⁇ 2d+l, where d is the attractor fractal dimension.
  • the dimension m is too small, and the reconstructed attractor cannot be completely folded; but m is too large, which brings a lot of unnecessary calculations to the invariants such as the actual calculation Lyapimov index. It also increases the effect of noise pollution such as rounding errors and instrument measurement errors.
  • CCao method is used to determine the best embedding dimension. It determines the best " ⁇ dimension when the scalar quantity (correlation dimension) changes with the embedding dimension. When E!] reaches the saturation point The corresponding value is the best ⁇ . Its advantages are: a) does not require many data points, b) can clearly distinguish between noise and chaotic signals, c) still applies to sequences with high-dimensional attractors, d) calculation efficient.
  • the Lyapunov exponent is an important kinetic parameter describing the dynamic properties of a nonlinear system. It represents the average exponential rate of adjacent scatter or convergence in the phase space.
  • ⁇ is called the Lyapunov exponent. If ⁇ is negative, it means that the trajectory of the phase space is contracted, no chaos is generated, the zero index represents the motion along the trajectory below the exponential velocity, and the positive exponent is the distance between the adjacent trajectories with the time index. Growth, showing a sensitive dependence on the initial value, the system is chaotic. So even if the size of the Lyapunov exponent is unknown, the type of exponential notation can provide a qualitative picture of the power system.
  • the phase space is reconstructed using the delay coordinate method.
  • search for a nearest neighbor point in the point set ⁇ Xi ⁇ to form an initial vector, and record its length as L(t.), so that it evolves to time along the 3 ⁇ 4 ⁇ in an appropriate time.
  • ⁇ the initial length evolves to L'd), with an exponential growth rate representing the length of the vector over this time period, T.
  • each evolution vector should have a relatively small length, 2.
  • the evolution vector should be kept at a small angle to the replaced vector. If the above-mentioned conditions cannot be found, the current vector is temporarily retained. The above process proceeds to the end point of the point set ⁇ Xi ⁇ , and the average of the exponential growth rate is taken as the estimated value of the largest Lyapunov exponent.
  • N k the total number of steps in evolution and k represents a constant.
  • the data obtained by the six methods are analyzed separately.
  • the sequence data points we selected are 80,000, after 20s.
  • the flat-recovery method is shown in Figure 1A
  • the squatting method is shown in Figure 2A.
  • Fig. 3A the method of diarrhea and diarrhea is shown in Fig. 4A.
  • the technique of stalking the dragon is shown in Fig. 5A
  • Fig. 6A the method of locating the turtle is shown in Fig.
  • the two parameters can be used to reconstruct the phase space reconstruction attractor graph.
  • the flattening method is shown in Fig. 1B
  • the trickle-removing method is shown in Fig. 2B.
  • the method of Xu disease replenishing and diarrhea is shown in Fig. 4B
  • the technique of the dragon dragon swinging tail is shown in Fig. 5B. It can be seen from these six graphs that the attractors of the six waveforms corresponding to the waveform are all specific, and different techniques exhibit different shapes, and these signals can be initially determined to be chaotic.
  • the maximum Lyapunov exponent (L) is used to quantitatively analyze the degree of chaos of these six sequences.
  • the method of flattening and diarrhea is shown in Figure ic, and the method of tamping and replenishing is shown in Figure 2C.
  • the method of dying and diarrhea is shown in Fig. 4C.
  • the technique of swaying the dragon is shown in Fig. 5C.
  • the attractor structures of the six methods seem to be the same, but their Lyapunov exponents are different.
  • the Lyapunov exponents corresponding to the signals of the six methods are: 1.7691, 1.7333, 1.7676, 1.7635, 1.5934, 1.7536.
  • the difference in the Lyapunov exponent reflects the signal.
  • the difference in evolution over time. Therefore, it can be considered that the coding of neural activity information caused by each acupuncture method has its own unique attractor ring, and on this basis, there is a Lyapunov exponent reflecting its eigenfeature.

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  • Health & Medical Sciences (AREA)
  • Rehabilitation Therapy (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Finger-Pressure Massage (AREA)
  • Electrotherapy Devices (AREA)

Abstract

L'invention porte sur un équipement thérapeutique à aiguille, à partir d'informations biologiques pour un traitement d'acupuncture, qui est induit par manipulation d'une stimulation d'acupuncture. La séquence d'impulsions électriques de l'équipement stimule un point d'acupuncture d'un animal par manipulation d'acupuncture. Le code d'introduction crée un potentiel de pointe de neurone, comprenant des informations biologiques qui sont induites dans des neurones de grande plage dynamique de la colonne vertébrale d'un animal en tant que source de signaux d'une impulsion électrique, et sont émis à l'électrode du traitement d'acupuncture après amplification. Une manipulation d'acupuncture comprend 6 sortes de manipulations duplex et 6 sortes de manipulations simplex.
PCT/CN2008/001390 2007-09-28 2008-07-29 Equipement thérapeutique à aiguille à partir d'informations biologiques pour un traitement d'acupuncture WO2009039724A1 (fr)

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CN2007101336560A CN101172188B (zh) 2007-09-28 2007-09-28 一种由针灸针刺手法刺激引发的生物信息针疗仪

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CN101172188B (zh) * 2007-09-28 2011-07-27 苏州医疗用品厂有限公司 一种由针灸针刺手法刺激引发的生物信息针疗仪
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