WO2009027766A3 - Nouvelles formes solides cristallines de la base o-desvenlafaxine - Google Patents

Nouvelles formes solides cristallines de la base o-desvenlafaxine Download PDF

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Publication number
WO2009027766A3
WO2009027766A3 PCT/IB2007/004654 IB2007004654W WO2009027766A3 WO 2009027766 A3 WO2009027766 A3 WO 2009027766A3 IB 2007004654 W IB2007004654 W IB 2007004654W WO 2009027766 A3 WO2009027766 A3 WO 2009027766A3
Authority
WO
WIPO (PCT)
Prior art keywords
crystalline solid
solid forms
new crystalline
desvenlafaxine base
base
Prior art date
Application number
PCT/IB2007/004654
Other languages
English (en)
Other versions
WO2009027766A2 (fr
Inventor
Velez Monica Benito
Iolanda Chamorro
Original Assignee
Medichem Sa
Velez Monica Benito
Iolanda Chamorro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem Sa, Velez Monica Benito, Iolanda Chamorro filed Critical Medichem Sa
Publication of WO2009027766A2 publication Critical patent/WO2009027766A2/fr
Publication of WO2009027766A3 publication Critical patent/WO2009027766A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

L'invention concerne de manière générale des formes polymorphes cristallines de la base O-desméthylvenlafaxine, appelées formes A et B de la base O-desméthylvenlafaxine, ainsi que des méthodes permettant de préparer et d'obtenir lesdites formes.
PCT/IB2007/004654 2006-12-22 2007-12-21 Nouvelles formes solides cristallines de la base o-desvenlafaxine WO2009027766A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87658006P 2006-12-22 2006-12-22
US60/876,580 2006-12-22

Publications (2)

Publication Number Publication Date
WO2009027766A2 WO2009027766A2 (fr) 2009-03-05
WO2009027766A3 true WO2009027766A3 (fr) 2009-04-23

Family

ID=40298639

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/004654 WO2009027766A2 (fr) 2006-12-22 2007-12-21 Nouvelles formes solides cristallines de la base o-desvenlafaxine

Country Status (2)

Country Link
AR (1) AR064507A1 (fr)
WO (1) WO2009027766A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8933123B2 (en) 2010-10-08 2015-01-13 Cadila Healthcare Limited Polymorphic forms of O-desmethyl-venlafaxine succinate
CN114478271A (zh) * 2021-12-13 2022-05-13 植恩生物技术股份有限公司 琥珀酸去甲文拉法辛制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030045583A1 (en) * 2001-02-12 2003-03-06 American Home Products Corporation Novel succinate salt of O-desmethyl-venlafaxine
US20060058552A1 (en) * 2002-06-10 2006-03-16 Wyeth Novel formate salt of O-desmethyl-venlafaxine
WO2007120925A2 (fr) * 2006-04-17 2007-10-25 Teva Pharmeceutical Industries Ltd. Formes cristallines du o-desmethylvenlafaxine
WO2008035369A2 (fr) * 2006-06-30 2008-03-27 Alembic Limited Nouvelle forme de o-desméthyl venlafaxine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030045583A1 (en) * 2001-02-12 2003-03-06 American Home Products Corporation Novel succinate salt of O-desmethyl-venlafaxine
US20060058552A1 (en) * 2002-06-10 2006-03-16 Wyeth Novel formate salt of O-desmethyl-venlafaxine
WO2007120925A2 (fr) * 2006-04-17 2007-10-25 Teva Pharmeceutical Industries Ltd. Formes cristallines du o-desmethylvenlafaxine
WO2008035369A2 (fr) * 2006-06-30 2008-03-27 Alembic Limited Nouvelle forme de o-desméthyl venlafaxine

Also Published As

Publication number Publication date
WO2009027766A2 (fr) 2009-03-05
AR064507A1 (es) 2009-04-08

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