WO2009026133A3 - Transdermal bisoprolol delivery system - Google Patents

Transdermal bisoprolol delivery system Download PDF

Info

Publication number
WO2009026133A3
WO2009026133A3 PCT/US2008/073270 US2008073270W WO2009026133A3 WO 2009026133 A3 WO2009026133 A3 WO 2009026133A3 US 2008073270 W US2008073270 W US 2008073270W WO 2009026133 A3 WO2009026133 A3 WO 2009026133A3
Authority
WO
WIPO (PCT)
Prior art keywords
bisoprolol
transdermal
delivery system
delivery
rate
Prior art date
Application number
PCT/US2008/073270
Other languages
French (fr)
Other versions
WO2009026133A2 (en
Inventor
Jianye Wen
Sangita Ghosh
Delphine Imbert
Tyler D. Westcott
Original Assignee
Alza Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corporation filed Critical Alza Corporation
Publication of WO2009026133A2 publication Critical patent/WO2009026133A2/en
Publication of WO2009026133A3 publication Critical patent/WO2009026133A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Abstract

A transdermal bisoprolol delivery system to an individual in need thereof. The system includes a backing layer, a reservoir disposed proximally relative to the backing layer. The reservoir has a polymeric composition containing an amount of bisoprolol or a pharmaceutically acceptable salt thereof sufficient for multiple-day delivery. The system can have a rate-control layer to control the rate of bisoprolol delivery to the user.
PCT/US2008/073270 2007-08-17 2008-08-15 Transdermal bisoprolol delivery system WO2009026133A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96507907P 2007-08-17 2007-08-17
US60/965,079 2007-08-17

Publications (2)

Publication Number Publication Date
WO2009026133A2 WO2009026133A2 (en) 2009-02-26
WO2009026133A3 true WO2009026133A3 (en) 2010-04-01

Family

ID=39769545

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/073270 WO2009026133A2 (en) 2007-08-17 2008-08-15 Transdermal bisoprolol delivery system

Country Status (1)

Country Link
WO (1) WO2009026133A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8512742B2 (en) 2009-05-01 2013-08-20 Hisamitsu Pharmaceutical Co., Inc. Transdermal preparation

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005042055A2 (en) * 2003-10-28 2005-05-12 Noven Pharmaceuticals, Inc. Transdermal drug delivery device
US20060078604A1 (en) * 2004-10-08 2006-04-13 Noven Pharmaceuticals, Inc. Transdermal drug delivery device including an occlusive backing
WO2006080199A1 (en) * 2005-01-31 2006-08-03 Hisamitsu Pharmaceutical Co., Inc. Patch
WO2007029781A1 (en) * 2005-09-09 2007-03-15 Nitto Denko Corporation Adhesive preparation containing bisoprolol
WO2007035939A2 (en) * 2005-09-23 2007-03-29 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
WO2007065303A1 (en) * 2005-12-09 2007-06-14 Beijing Kangbeide Pharmaceutical Technology Development Co., Ltd. Transdermal patch containing isosorbide dinitrate and bisoprolol

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005042055A2 (en) * 2003-10-28 2005-05-12 Noven Pharmaceuticals, Inc. Transdermal drug delivery device
US20060078604A1 (en) * 2004-10-08 2006-04-13 Noven Pharmaceuticals, Inc. Transdermal drug delivery device including an occlusive backing
WO2006080199A1 (en) * 2005-01-31 2006-08-03 Hisamitsu Pharmaceutical Co., Inc. Patch
EP1847264A1 (en) * 2005-01-31 2007-10-24 Hisamitsu Pharmaceutical Co. Inc. Patch
WO2007029781A1 (en) * 2005-09-09 2007-03-15 Nitto Denko Corporation Adhesive preparation containing bisoprolol
EP1932523A1 (en) * 2005-09-09 2008-06-18 Nitto Denko Corporation Adhesive preparation containing bisoprolol
WO2007035939A2 (en) * 2005-09-23 2007-03-29 Alza Corporation High enhancer-loading polyacrylate formulation for transdermal applications
WO2007065303A1 (en) * 2005-12-09 2007-06-14 Beijing Kangbeide Pharmaceutical Technology Development Co., Ltd. Transdermal patch containing isosorbide dinitrate and bisoprolol
US20080292685A1 (en) * 2005-12-09 2008-11-27 Beijing Kangbeide Pharmaceutical Technology Development Co., Ltd Transdermal Patch Containing Isosorbide Dinitrate and Bisoprolol

Also Published As

Publication number Publication date
WO2009026133A2 (en) 2009-02-26

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