WO2009025551A3 - New molecular markers for detection of squamous cell carcinomas and adenocarcinomas and high-grade precursor lesions thereof - Google Patents

New molecular markers for detection of squamous cell carcinomas and adenocarcinomas and high-grade precursor lesions thereof Download PDF

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Publication number
WO2009025551A3
WO2009025551A3 PCT/NL2008/050556 NL2008050556W WO2009025551A3 WO 2009025551 A3 WO2009025551 A3 WO 2009025551A3 NL 2008050556 W NL2008050556 W NL 2008050556W WO 2009025551 A3 WO2009025551 A3 WO 2009025551A3
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WO
WIPO (PCT)
Prior art keywords
detection
squamous cell
adenocarcinomas
precursor lesions
molecular markers
Prior art date
Application number
PCT/NL2008/050556
Other languages
French (fr)
Other versions
WO2009025551A2 (en
Inventor
Christophorus Joannes Lambertus Maria Meijer
Petrus Josephus Ferdinandus Snijders
Renske Daniela Maria Steenbergen
Original Assignee
Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek En Patientenzorg
Christophorus Joannes Lambertus Maria Meijer
Petrus Josephus Ferdinandus Snijders
Renske Daniela Maria Steenbergen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek En Patientenzorg, Christophorus Joannes Lambertus Maria Meijer, Petrus Josephus Ferdinandus Snijders, Renske Daniela Maria Steenbergen filed Critical Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek En Patientenzorg
Priority to CA2697668A priority Critical patent/CA2697668A1/en
Priority to AU2008289729A priority patent/AU2008289729A1/en
Priority to CN200880112145A priority patent/CN101827948A/en
Priority to EP08793848A priority patent/EP2191017A2/en
Priority to JP2010521803A priority patent/JP2010537191A/en
Publication of WO2009025551A2 publication Critical patent/WO2009025551A2/en
Publication of WO2009025551A3 publication Critical patent/WO2009025551A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides for new markers for the detection of HPV-induced or lung squamous cell carcinoma and/or adenocarcinoma and high-grade precursor lesions thereof, comprising the genes of the present invention. Detection can take place by detection over expression or down regulation of said genes either by nucleic acid assay or by assays for the proteins produced by said genes.
PCT/NL2008/050556 2007-08-20 2008-08-20 New molecular markers for detection of squamous cell carcinomas and adenocarcinomas and high-grade precursor lesions thereof WO2009025551A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA2697668A CA2697668A1 (en) 2007-08-20 2008-08-20 New molecular markers for detection of squamous cell carcinomas and adenocarcinomas and high-grade precursor lesions thereof
AU2008289729A AU2008289729A1 (en) 2007-08-20 2008-08-20 New molecular markers for detection of squamous cell carcinomas and adenocarcinomas and high-grade precursor lesions thereof
CN200880112145A CN101827948A (en) 2007-08-20 2008-08-20 New molecular markers for detection of squamous cell carcinomas and adenocarcinomas and high-grade precursor lesions thereof
EP08793848A EP2191017A2 (en) 2007-08-20 2008-08-20 New molecular markers for detection of squamous cell carcinomas and adenocarcinomas and high-grade precursor lesions thereof
JP2010521803A JP2010537191A (en) 2007-08-20 2008-08-20 A new molecular marker for detection of squamous cell carcinoma and adenocarcinoma and its high-grade precursor lesions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07114580 2007-08-20
EP07114580.9 2007-08-20

Publications (2)

Publication Number Publication Date
WO2009025551A2 WO2009025551A2 (en) 2009-02-26
WO2009025551A3 true WO2009025551A3 (en) 2009-06-25

Family

ID=38613252

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2008/050556 WO2009025551A2 (en) 2007-08-20 2008-08-20 New molecular markers for detection of squamous cell carcinomas and adenocarcinomas and high-grade precursor lesions thereof

Country Status (6)

Country Link
EP (1) EP2191017A2 (en)
JP (1) JP2010537191A (en)
CN (1) CN101827948A (en)
AU (1) AU2008289729A1 (en)
CA (1) CA2697668A1 (en)
WO (1) WO2009025551A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103205433B (en) * 2013-04-03 2014-06-04 复旦大学附属肿瘤医院 Gene for lung cancer prognosis and application thereof

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 29 September 2000 (2000-09-29), SUGANO S. ET AL.: "Homo sapiens cDNA: FLJ21291 fis, clone COL01963", XP002502058, retrieved from EBI Database accession no. AK024944 *
DATABASE EMBL 29 September 2000 (2000-09-29), SUGANO S. ET AL.: "Homo sapiens cDNA: FLJ21482 fis, clone COL05135", XP002524337, retrieved from EBI Database accession no. AK025135 *
DATABASE EMBL 4 December 2003 (2003-12-04), SCHLEGEL R. ET AL.: "Prostate cancer marker cDNA", XP002524338, retrieved from EBI Database accession no. ADB75498 *
DATABASE EMBL 4 February 1997 (1997-02-04), PANAREOUT C.: "H. sapiens mRNA for adaptor protein p150", XP002524339, retrieved from EBI Database accession no. Y08991 *
HAUSEN ZUR H.: "PAPILLOMAVIRUSES AND CANCER: FROM BASIC STUDIES TO CLINICAL APPLICATION", NATURE REVIEWS. CANCER, NATUR PUBLISHING GROUP, LONDON, GB, vol. 2, no. 5, May 2002 (2002-05-01), pages 342 - 350, XP008015401, ISSN: 1474-175X *
HESELMEYER K. ET AL.: "GAIN OF CHROMOSOME 3Q DEFINES THE TRANSITION FROM SEVERE DYSPLASIA2 TO INVASIVE CARCINOMA OF THE UTERINE CERVIX", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 93, 9 January 1996 (1996-01-09), pages 479 - 484, XP002066427, ISSN: 0027-8424 *
MA Y.-Y. ET AL.: "PIK3CA as an oncogene in cervical cancer", ONCOGENE, vol. 19, no. 23, 25 May 2000 (2000-05-25), pages 2739 - 2744, XP002459619, ISSN: 0950-9232 *
WILTING S.M. ET AL.: "Increased gene copy numbers at chromosome 20q are frequent in both squamous cell carcinomas and adenocarcinomas of the cervix", JOURNAL OF PATHOLOGY, vol. 209, no. 2, June 2006 (2006-06-01), pages 220 - 230, XP002459618, ISSN: 0022-3417 *

Also Published As

Publication number Publication date
JP2010537191A (en) 2010-12-02
CN101827948A (en) 2010-09-08
EP2191017A2 (en) 2010-06-02
WO2009025551A2 (en) 2009-02-26
CA2697668A1 (en) 2009-02-26
AU2008289729A1 (en) 2009-02-26

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