WO2009010991A3 - Purification process to prepare highly pure anastrozole - Google Patents

Purification process to prepare highly pure anastrozole Download PDF

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Publication number
WO2009010991A3
WO2009010991A3 PCT/IN2008/000455 IN2008000455W WO2009010991A3 WO 2009010991 A3 WO2009010991 A3 WO 2009010991A3 IN 2008000455 W IN2008000455 W IN 2008000455W WO 2009010991 A3 WO2009010991 A3 WO 2009010991A3
Authority
WO
WIPO (PCT)
Prior art keywords
purification process
highly pure
prepare highly
anastrozole
pure anastrozole
Prior art date
Application number
PCT/IN2008/000455
Other languages
French (fr)
Other versions
WO2009010991A2 (en
Inventor
Rahul Saxena
Naresh Kumar Verma
Anshul Kumar Jain
Chidambaram Ventateswaran Srinivasan
Lalit Wadhwa.
Original Assignee
Ind-Swift Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind-Swift Laboratories Limited filed Critical Ind-Swift Laboratories Limited
Publication of WO2009010991A2 publication Critical patent/WO2009010991A2/en
Publication of WO2009010991A3 publication Critical patent/WO2009010991A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

The present invention relates to an industrially advantageous method for the purification of anastrozole of Formula (I), wherein isoanastrozole of Formula (VI), present in crude anastrozole as an impurity, is removed by using gel purification.
PCT/IN2008/000455 2007-07-17 2008-07-16 Purification process to prepare highly pure anastrozole WO2009010991A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1509DE2007 2007-07-17
IN1509/DEL/2007 2007-07-17

Publications (2)

Publication Number Publication Date
WO2009010991A2 WO2009010991A2 (en) 2009-01-22
WO2009010991A3 true WO2009010991A3 (en) 2010-11-11

Family

ID=40260191

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2008/000455 WO2009010991A2 (en) 2007-07-17 2008-07-16 Purification process to prepare highly pure anastrozole

Country Status (1)

Country Link
WO (1) WO2009010991A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20130285A1 (en) * 2013-05-14 2014-11-15 Corden Pharma Latina S P A Con Uni Co Socio METHOD FOR THE PREPARATION OF PHARMACEUTICAL GRADE ANASTROZOL

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126425A (en) * 1964-03-24 p-xylene
WO2005105762A1 (en) * 2004-05-05 2005-11-10 Natco Pharma Limited Improved process for the preparation of high purity anastrozole
US20060035950A1 (en) * 2004-08-09 2006-02-16 Mohammed Alnabari Novel processes for preparing substantially pure anastrozole
WO2006108155A2 (en) * 2005-04-06 2006-10-12 Sicor, Inc. Process for the preparation of anastrozole
WO2007039913A1 (en) * 2005-10-05 2007-04-12 Usv Limited Process for the preparation of 2,2’-[5-(1,2,4-triazole-1-ylmethyl) -1,3-phenylene] di (2-methylpropionitrile).
WO2007105231A1 (en) * 2006-03-10 2007-09-20 Shilpa Medicare Ltd. Improved process for high purity anastrozole
WO2007134846A2 (en) * 2006-05-19 2007-11-29 Synthon B.V. Process for purification of anastrozole
WO2007141799A1 (en) * 2006-06-05 2007-12-13 Cadila Healthcare Limited A process for preparing pure anastrozole

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126425A (en) * 1964-03-24 p-xylene
WO2005105762A1 (en) * 2004-05-05 2005-11-10 Natco Pharma Limited Improved process for the preparation of high purity anastrozole
US20060035950A1 (en) * 2004-08-09 2006-02-16 Mohammed Alnabari Novel processes for preparing substantially pure anastrozole
WO2006108155A2 (en) * 2005-04-06 2006-10-12 Sicor, Inc. Process for the preparation of anastrozole
WO2007039913A1 (en) * 2005-10-05 2007-04-12 Usv Limited Process for the preparation of 2,2’-[5-(1,2,4-triazole-1-ylmethyl) -1,3-phenylene] di (2-methylpropionitrile).
WO2007105231A1 (en) * 2006-03-10 2007-09-20 Shilpa Medicare Ltd. Improved process for high purity anastrozole
WO2007134846A2 (en) * 2006-05-19 2007-11-29 Synthon B.V. Process for purification of anastrozole
WO2007141799A1 (en) * 2006-06-05 2007-12-13 Cadila Healthcare Limited A process for preparing pure anastrozole

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FRANCK H. DICKEY: "The preparation of specific adsorbents", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 35, no. 5, 15 May 1949 (1949-05-15) *

Also Published As

Publication number Publication date
WO2009010991A2 (en) 2009-01-22

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