WO2008152729A1 - リスペリドンを含むゼリー状の医薬組成物 - Google Patents

リスペリドンを含むゼリー状の医薬組成物 Download PDF

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Publication number
WO2008152729A1
WO2008152729A1 PCT/JP2007/062110 JP2007062110W WO2008152729A1 WO 2008152729 A1 WO2008152729 A1 WO 2008152729A1 JP 2007062110 W JP2007062110 W JP 2007062110W WO 2008152729 A1 WO2008152729 A1 WO 2008152729A1
Authority
WO
WIPO (PCT)
Prior art keywords
jelly
pharmaceutical composition
risperidone
composition containing
containing risperidone
Prior art date
Application number
PCT/JP2007/062110
Other languages
English (en)
French (fr)
Inventor
Kio Natsume
Masatake Dairaku
Hiroshi Ninomiya
Noboru Tamura
Original Assignee
Teikokumedix Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikokumedix Co., Ltd. filed Critical Teikokumedix Co., Ltd.
Priority to PCT/JP2007/062110 priority Critical patent/WO2008152729A1/ja
Publication of WO2008152729A1 publication Critical patent/WO2008152729A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

　リスペリドンとの配合性に優れるゼリー基剤、添加剤を探索することにより、安定性に優れかつ服用が容易である、リスペリドンを含むゼリー状の医薬組成物を提供する。カロブビーンガム及びキサンタンガムを組合わせて、リスペリドンを含むゼリー状医薬組成物のゼリー基剤とする。好ましくは、糖アルコール類及び乳糖から選ばれる矯味剤を配合する。
PCT/JP2007/062110 2007-06-15 2007-06-15 リスペリドンを含むゼリー状の医薬組成物 WO2008152729A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/062110 WO2008152729A1 (ja) 2007-06-15 2007-06-15 リスペリドンを含むゼリー状の医薬組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/062110 WO2008152729A1 (ja) 2007-06-15 2007-06-15 リスペリドンを含むゼリー状の医薬組成物

Publications (1)

Publication Number Publication Date
WO2008152729A1 true WO2008152729A1 (ja) 2008-12-18

Family

ID=40129346

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/062110 WO2008152729A1 (ja) 2007-06-15 2007-06-15 リスペリドンを含むゼリー状の医薬組成物

Country Status (1)

Country Link
WO (1) WO2008152729A1 (ja)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11123231A (ja) * 1997-10-21 1999-05-11 Ohta Pharmaceut Co Ltd 袋状容器入り医療用ゼリー剤
JP2000256181A (ja) * 1999-03-03 2000-09-19 Ohta Pharmaceut Co Ltd 袋状容器入り医療用ゼリー剤
WO2005123084A1 (en) * 2004-06-15 2005-12-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Orally disintegrating pharmaceutical composition comprising risperidone

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11123231A (ja) * 1997-10-21 1999-05-11 Ohta Pharmaceut Co Ltd 袋状容器入り医療用ゼリー剤
JP2000256181A (ja) * 1999-03-03 2000-09-19 Ohta Pharmaceut Co Ltd 袋状容器入り医療用ゼリー剤
WO2005123084A1 (en) * 2004-06-15 2005-12-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Orally disintegrating pharmaceutical composition comprising risperidone

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MORITA T.: "Fukuyaku Hojo Jelly no Kaihatsu", YAKUGAKU ZASSHI, vol. 123, no. 8, 2003, pages 665 - 671, XP003024614 *
SANO M.: "Kakushu Tennen Gum no Zonen.Kecchaku ni Tsuite -Sono 1-", NEW FOOD INDUSTRY, vol. 20, no. 9, 1978, pages 20 - 28, XP003024615 *

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