WO2008150101A3 - Chimeric polypeptide including a mussel adheisve protein and extracellular matrix - Google Patents

Chimeric polypeptide including a mussel adheisve protein and extracellular matrix Download PDF

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Publication number
WO2008150101A3
WO2008150101A3 PCT/KR2008/003130 KR2008003130W WO2008150101A3 WO 2008150101 A3 WO2008150101 A3 WO 2008150101A3 KR 2008003130 W KR2008003130 W KR 2008003130W WO 2008150101 A3 WO2008150101 A3 WO 2008150101A3
Authority
WO
WIPO (PCT)
Prior art keywords
extracellular matrix
chimeric polypeptide
mussel
protein
adheisve
Prior art date
Application number
PCT/KR2008/003130
Other languages
French (fr)
Other versions
WO2008150101A2 (en
Inventor
Hyung-Joon Cha
Hyo Jin Yoo
Young Hoon Song
Dong Kyun Kang
Young Soo Gim
Original Assignee
Postech Acad Ind Found
Gluegen Technology Inc
Jung Oh Gi
Hyung-Joon Cha
Hyo Jin Yoo
Young Hoon Song
Dong Kyun Kang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Postech Acad Ind Found, Gluegen Technology Inc, Jung Oh Gi, Hyung-Joon Cha, Hyo Jin Yoo, Young Hoon Song, Dong Kyun Kang filed Critical Postech Acad Ind Found
Publication of WO2008150101A2 publication Critical patent/WO2008150101A2/en
Publication of WO2008150101A3 publication Critical patent/WO2008150101A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention is related to a chimeric polypeptide comprising a mussel adhesive protein and a biofunctional peptide coupled thereto, a bioadhesive extracellular matrix comprising the chimeric polypeptide, and a method of controlling an adhesiveness of an extracellular matrix.
PCT/KR2008/003130 2007-06-04 2008-06-04 Chimeric polypeptide including a mussel adheisve protein and extracellular matrix WO2008150101A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94187207P 2007-06-04 2007-06-04
US60/941,872 2007-06-04

Publications (2)

Publication Number Publication Date
WO2008150101A2 WO2008150101A2 (en) 2008-12-11
WO2008150101A3 true WO2008150101A3 (en) 2009-01-29

Family

ID=40094304

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2008/003130 WO2008150101A2 (en) 2007-06-04 2008-06-04 Chimeric polypeptide including a mussel adheisve protein and extracellular matrix

Country Status (1)

Country Link
WO (1) WO2008150101A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8722617B2 (en) 2007-12-31 2014-05-13 Postech Academy-Industry Foundation Mussel adhesive protein derived vectors for gene delivery
JP2012526155A (en) * 2009-08-25 2012-10-25 ポステック アカデミー−インダストリー ファンデーション Coacervate containing anionic polymer in mussel adhesion protein or its variant
WO2012083424A1 (en) * 2010-12-21 2012-06-28 The University Of Western Ontario Novel amino acid linker sequences for ligand immobilization
KR101311325B1 (en) * 2012-09-13 2013-09-30 이상재 Synthetically designed 3d microenvironment structure
US10449267B2 (en) 2013-11-13 2019-10-22 Massachusetts Institute Of Technology Self-assembling underwater adhesives
US11578106B2 (en) 2015-08-07 2023-02-14 TME Therapeutics Co., Ltd. Surfactant adhesive composition
KR20170017499A (en) * 2015-08-07 2017-02-15 콜로디스 바이오사이언스, 인코포레이티드 Biofunctional Adhesive Composition
DE202015006574U1 (en) 2015-09-17 2015-11-13 Universität Leipzig Peptide for coating surfaces
WO2017101026A1 (en) * 2015-12-15 2017-06-22 江阴市本特塞缪森生命科学研究院有限公司 Composition of mussel adhesive protein and growth factor
CN108395483A (en) * 2018-02-13 2018-08-14 天津大学 A kind of synthetic method of the multi-functional fusion protein of three block based on mussel attachment proteins/amphoteric ion polypeptide and application
CN108503712A (en) * 2018-03-14 2018-09-07 天津大学 With the difunctional mussel attachment proteins/amphoteric ion polypeptide amalgamation protein of adherency-anti-pollution and synthetic method
US20230056844A1 (en) * 2019-12-27 2023-02-23 Amolifescience Co., Ltd. Cell culture substrate and manufacturing method therefor
WO2021241782A1 (en) * 2020-05-28 2021-12-02 부산대학교 산학협력단 Fusion protein for cell culture containing extracellular matrix motif and use thereof
EP4244241A4 (en) * 2020-12-16 2024-05-01 Tme Therapeutics Co Ltd Protein substrate to bind growth factor
CN114044807B (en) * 2021-11-19 2023-08-22 浙江海洋大学 Mussel hypolipidemic oligopeptide for treating hyperlipidemia
WO2023158285A1 (en) * 2022-02-21 2023-08-24 TME Therapeutics Co., Ltd. Gf binding ecm mimetic coated microcarrier
CN117964785A (en) * 2024-04-01 2024-05-03 深圳易致生物科技有限公司 Recombinant collagen mussel mucin and expression method and application thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HWANG D.S. ET AL.: "Cell adhesion biomaterial based on mussel adhesive protein fused with RGD peptide", BIOMATERIALS, vol. 28, no. 28, 14 June 2007 (2007-06-14), pages 4039 - 4046, XP022153623 *
HWANG D.S. ET AL.: "Practical recombinant hybrid mussel bioadhesive fp-151", BIOMATERIALS, vol. 28, no. 24, May 2007 (2007-05-01), pages 3560 - 3568, XP025321212 *
HWANG D.S. ET AL.: "Recombinant mussel adhesive protein Mg fp-5 as cell adhesion biomaterial", JOURNAL OF BIOTECHNOLOGY, vol. 127, no. 4, 2006, pages 727 - 735, XP005810985 *
LOIZOU E. ET AL.: "Structural effects of crosslinking a biopolymer hydrogel derived from marine mussel adhesive protein", MACROMOL. BIOSCI., vol. 6, no. 9, 2006, pages 711 - 718, XP003021956 *

Also Published As

Publication number Publication date
WO2008150101A2 (en) 2008-12-11

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