WO2008140467A3 - Genetic markers and methods for improving dairy productivity and fitness traits - Google Patents

Genetic markers and methods for improving dairy productivity and fitness traits Download PDF

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Publication number
WO2008140467A3
WO2008140467A3 PCT/US2007/021187 US2007021187W WO2008140467A3 WO 2008140467 A3 WO2008140467 A3 WO 2008140467A3 US 2007021187 W US2007021187 W US 2007021187W WO 2008140467 A3 WO2008140467 A3 WO 2008140467A3
Authority
WO
WIPO (PCT)
Prior art keywords
animals
methods
traits
productivity
provides methods
Prior art date
Application number
PCT/US2007/021187
Other languages
French (fr)
Other versions
WO2008140467A2 (en
Inventor
Fengxing Du
Michael D. Grosz
Michael M. Lohuis
Nengbing Tao
Nicholas J. Nissing
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of WO2008140467A2 publication Critical patent/WO2008140467A2/en
Publication of WO2008140467A3 publication Critical patent/WO2008140467A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention provides methods for improving desirable animal traits including improved fitness and productivity in dairy animals. Also provided are methods for determining a dairy animal's genotype with respect to multiple markers associated with milk production, somatic cell score, daughter pregnancy rate, productive life, and/or net merit. The invention also provides methods for selecting or allocating animals for predetermined uses such as progeny testing or nucleus herd breeding, for picking potential parent animals for breeding, and for producing improved progeny animals. Also provided are methods for identifying genes and/or genetic markers for traits including fitness and productivity traits; including identifying markers that are in allelic association with the SNPs disclosed herein and for identifying the genotypes of a causative mutation underlying a quantitative trait locus (QTL). The invention further provides methods for genotyping animals for multiple SNPs associated with the traits described above.
PCT/US2007/021187 2006-09-29 2007-09-28 Genetic markers and methods for improving dairy productivity and fitness traits WO2008140467A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US84854106P 2006-09-29 2006-09-29
US60/848,541 2006-09-29
US91909907P 2007-03-20 2007-03-20
US60/919,099 2007-03-20
US93168007P 2007-05-24 2007-05-24
US60/931,680 2007-05-24

Publications (2)

Publication Number Publication Date
WO2008140467A2 WO2008140467A2 (en) 2008-11-20
WO2008140467A3 true WO2008140467A3 (en) 2016-06-09

Family

ID=40002777

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/021187 WO2008140467A2 (en) 2006-09-29 2007-09-28 Genetic markers and methods for improving dairy productivity and fitness traits

Country Status (1)

Country Link
WO (1) WO2008140467A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2693941A1 (en) * 2007-07-16 2009-01-22 Pfizer Inc. Methods of improving a genomic marker index of dairy animals and products
NZ591236A (en) * 2008-08-19 2012-11-30 Viking Genetics Fmba Methods for determining a breeding value based on a plurality of genetic markers
CN103576829B (en) * 2012-08-01 2016-04-20 复旦大学 Based on the cloud computing virtual machine dynamic dispatching method of genetic algorithm
BR102015025537A2 (en) * 2014-10-08 2016-04-12 Dow Agrosciences Llc gho / sec24b2 and sec24b1 nucleic acid molecules to control Coleoptera and Hemiptera pests
CN108324405B (en) * 2018-02-05 2019-11-12 杭州博古科技有限公司 One boar cultivates artificial insemination pregnancy rate evaluation system
CN117701727B (en) * 2023-12-04 2024-06-07 广西壮族自治区水牛研究所 SNP molecular marker combination related to size and birth weight of Mora buffalo based on whole genome sequencing screening and application

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040076977A1 (en) * 2000-10-31 2004-04-22 Georges Michel Alphonse Julien Marker assisted selection of bovine for improved milk production using diacylglycerol acyltransferase gene dgat1
WO2005030789A1 (en) * 2003-09-23 2005-04-07 The Arizona Board Of Regents On Behalf Of The University Of Arizona Adrenergic receptor snp for improved milking characteristics

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040076977A1 (en) * 2000-10-31 2004-04-22 Georges Michel Alphonse Julien Marker assisted selection of bovine for improved milk production using diacylglycerol acyltransferase gene dgat1
WO2005030789A1 (en) * 2003-09-23 2005-04-07 The Arizona Board Of Regents On Behalf Of The University Of Arizona Adrenergic receptor snp for improved milking characteristics

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
RON ET AL.: "Multiple Quantitative Trait Locus Analysis of Bovine Chromoseom 6 in the Israeli Holstein Population by a Daughter Design.", GENETICS, vol. 159, no. 2, October 2001 (2001-10-01), pages 727 - 735 *

Also Published As

Publication number Publication date
WO2008140467A2 (en) 2008-11-20

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