WO2008126065A3 - Polynucléotides et polypeptides impliqués dans le paludisme gestationnel, et applications biologiques - Google Patents

Polynucléotides et polypeptides impliqués dans le paludisme gestationnel, et applications biologiques Download PDF

Info

Publication number
WO2008126065A3
WO2008126065A3 PCT/IB2008/051482 IB2008051482W WO2008126065A3 WO 2008126065 A3 WO2008126065 A3 WO 2008126065A3 IB 2008051482 W IB2008051482 W IB 2008051482W WO 2008126065 A3 WO2008126065 A3 WO 2008126065A3
Authority
WO
WIPO (PCT)
Prior art keywords
polynucleotides
biological applications
polypeptides involved
gestational malaria
malaria
Prior art date
Application number
PCT/IB2008/051482
Other languages
English (en)
Other versions
WO2008126065A2 (fr
Inventor
Philippe Lucien Deloron
Ndam Nicaise Georges Tuikue
Gwladys Irenee Bertin
Peter David
Emmanuel Bischoff
Caroline Stephanie Proux
Jean-Yves Coppee
Ali Salanti
Thomas Lavstsen
Original Assignee
Inst Rech Developpement Ird
Pasteur Institut
Philippe Lucien Deloron
Ndam Nicaise Georges Tuikue
Gwladys Irenee Bertin
Peter David
Emmanuel Bischoff
Caroline Stephanie Proux
Jean-Yves Coppee
Ali Salanti
Thomas Lavstsen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Rech Developpement Ird, Pasteur Institut, Philippe Lucien Deloron, Ndam Nicaise Georges Tuikue, Gwladys Irenee Bertin, Peter David, Emmanuel Bischoff, Caroline Stephanie Proux, Jean-Yves Coppee, Ali Salanti, Thomas Lavstsen filed Critical Inst Rech Developpement Ird
Priority to EP08737901A priority Critical patent/EP2145003A2/fr
Priority to AP2009005041A priority patent/AP3116A/xx
Priority to US12/450,874 priority patent/US8563008B2/en
Publication of WO2008126065A2 publication Critical patent/WO2008126065A2/fr
Publication of WO2008126065A3 publication Critical patent/WO2008126065A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C07K16/205—Plasmodium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention est relative à de nouveaux antigènes impliqués dans le paludisme gestationnel et plus particulièrement à des séquences polynucléotidiques et polypeptidiques, des conjugués, des vecteurs de clonages comportant lesdites séquences en vue de la réalisation de compositions immunogènes et vaccins, d'anticorps et à leurs utilisation pour le traitement du paludisme gestationnel. L' invention vise également des méthodes et des kits de diagnostic.
PCT/IB2008/051482 2007-04-17 2008-04-17 Polynucléotides et polypeptides impliqués dans le paludisme gestationnel, et applications biologiques WO2008126065A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08737901A EP2145003A2 (fr) 2007-04-17 2008-04-17 Polynucléotides et polypeptides impliqués dans le paludisme gestationnel, et applications biologiques
AP2009005041A AP3116A (en) 2007-04-17 2008-04-17 Polynucleotides and polypeptides involved in gestational malaria, and biological applications
US12/450,874 US8563008B2 (en) 2007-04-17 2008-04-17 Polynucleotides and polypeptides involved in gestational malaria, and biological applications

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR07/02772 2007-04-17
FR0702772A FR2915207B1 (fr) 2007-04-17 2007-04-17 Polynucleotides et polypeptides impliques dans le paludisme gestationnel, et applications biologiques.

Publications (2)

Publication Number Publication Date
WO2008126065A2 WO2008126065A2 (fr) 2008-10-23
WO2008126065A3 true WO2008126065A3 (fr) 2008-12-31

Family

ID=38613117

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/051482 WO2008126065A2 (fr) 2007-04-17 2008-04-17 Polynucléotides et polypeptides impliqués dans le paludisme gestationnel, et applications biologiques

Country Status (5)

Country Link
US (1) US8563008B2 (fr)
EP (1) EP2145003A2 (fr)
AP (1) AP3116A (fr)
FR (1) FR2915207B1 (fr)
WO (1) WO2008126065A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201318084D0 (en) * 2013-10-11 2013-11-27 Isis Innovation Malaria vaccination
US9321834B2 (en) 2013-12-05 2016-04-26 Leidos, Inc. Anti-malarial compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006124712A2 (fr) * 2005-05-16 2006-11-23 Merck & Co., Inc. Procede d'augmentation de l'immunigenicite des antigenes de plasmodium
US20070036819A1 (en) * 2005-08-09 2007-02-15 Michal Fried Malaria vaccines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006124712A2 (fr) * 2005-05-16 2006-11-23 Merck & Co., Inc. Procede d'augmentation de l'immunigenicite des antigenes de plasmodium
US20070036819A1 (en) * 2005-08-09 2007-02-15 Michal Fried Malaria vaccines

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE UniProt [online] 1 March 2003 (2003-03-01), "Putative uncharacterized protein PFI1785w.", XP002457420, retrieved from EBI accession no. UNIPROT:Q8I2F1 Database accession no. Q8I2F1 *
FRANCIS SUSAN E ET AL: "Six genes are preferentially transcribed by the circulating and sequestered forms of Plasmodium falciparum parasites that infect pregnant women.", INFECTION AND IMMUNITY OCT 2007, vol. 75, no. 10, October 2007 (2007-10-01), pages 4838 - 4850, XP002500501, ISSN: 0019-9567 *
FRIED MICHAL ET AL: "The distinct proteome of placental malaria parasites.", MOLECULAR AND BIOCHEMICAL PARASITOLOGY SEP 2007, vol. 155, no. 1, September 2007 (2007-09-01), pages 57 - 65, XP002500500, ISSN: 0166-6851 *
TUIKUE NDAM NICAISE ET AL: "Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression.", PLOS ONE 2008, vol. 3, no. 3, 26 March 2008 (2008-03-26), pages e1855, XP002500502, ISSN: 1932-6203 *

Also Published As

Publication number Publication date
FR2915207B1 (fr) 2012-10-05
US8563008B2 (en) 2013-10-22
EP2145003A2 (fr) 2010-01-20
AP2009005041A0 (en) 2009-12-31
FR2915207A1 (fr) 2008-10-24
AP3116A (en) 2015-02-28
WO2008126065A2 (fr) 2008-10-23
US20100255018A1 (en) 2010-10-07

Similar Documents

Publication Publication Date Title
EP2332970A3 (fr) Exotoxines de Pseudomonas mutées a antigenicité reduite
WO2006138004A3 (fr) Compositions immunogenes pour chlamydia trachomatis
WO2009015842A3 (fr) Nouveaux épitopes immunogènes destinés à l'immunothérapie
WO2013115926A3 (fr) Conjugués aspartyl-arnt synthétase-fc
EP2826791A3 (fr) Anticorps anti-C5aR humanisés
WO2014089335A3 (fr) Protéines de liaison à l'antigène bcma
WO2016176624A3 (fr) Pestivirus porcin, vaccins et dosages
WO2007106476A3 (fr) Compositions et procédés pour renforcer l'immunogénicité d'antigènes
WO2008077945A3 (fr) Séquences d'acides aminés dirigées contre des chimiokines et polypeptides comprenant celles-ci pour le traitement de maladies et de troubles liés aux chimiokines
WO2008124647A3 (fr) Compositions immunogènes comportant des polypeptides de mycobacterium tuberculosis et des fusions de ceux-ci
WO2011008974A3 (fr) Compositions à base de protéine f du vrs et procédés de fabrication associés
WO2010136311A3 (fr) Compositions et procédés de ciblage de la protéine c3b de complément par des anticorps
WO2014106015A3 (fr) Compositions protéiques à liaison multivalente
WO2011032161A8 (fr) Vaccins dirigés contre les cellules de langerhans
MX2009001778A (es) Peptidos pcpa inmunogenicos y usos de los mismos.
WO2008098917A3 (fr) Nouveaux anticorps
WO2008137881A3 (fr) Protéines d'ehrlichia ewingii, acides nucléiques, et procédés pour leur utilisation
WO2008020335A8 (fr) Compositions immunogènes pour streptococcus agalactiae
WO2008124646A3 (fr) Utilisation de protéines amyloïdes en tant qu'échafaudages pour des vaccins
MX2010001723A (es) Formulaciones de anticuerpos y moleculas de fusion-fc usando policationes.
EP2251035A3 (fr) Nouveaux facteurs de virulence de la pneumonie à streptocoques
WO2011116212A3 (fr) Agents de liaison de récepteur de protéine morphogénétique osseuse et procédés de leur utilisation
WO2010115995A3 (fr) Séquences d'acides aminés améliorées dirigées contre l'il-6r et polypeptides les comprenant pour le traitement des maladies et des troubles liés à l'il-6r
WO2013040478A3 (fr) Compositions dérivées de hyr1 et méthodes de traitement les utilisant
WO2009035959A3 (fr) Methodes de radiofluoration

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08737901

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 12450874

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2008737901

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2008737901

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 6890/DELNP/2009

Country of ref document: IN