WO2008117801A1 - 軟骨保護組成物 - Google Patents

軟骨保護組成物 Download PDF

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Publication number
WO2008117801A1
WO2008117801A1 PCT/JP2008/055591 JP2008055591W WO2008117801A1 WO 2008117801 A1 WO2008117801 A1 WO 2008117801A1 JP 2008055591 W JP2008055591 W JP 2008055591W WO 2008117801 A1 WO2008117801 A1 WO 2008117801A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition
cartilage protection
water
acetic acid
acid bacterium
Prior art date
Application number
PCT/JP2008/055591
Other languages
English (en)
French (fr)
Inventor
Shin Ogawa
Original Assignee
Mizkan Group Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mizkan Group Corporation filed Critical Mizkan Group Corporation
Publication of WO2008117801A1 publication Critical patent/WO2008117801A1/ja

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

【課題】本発明は、安全性が高く、より軟骨保護効果の強い軟骨保護組成物を提供することを目的とするものである。 【解決手段】本発明は、酢酸菌(例えば、アセトバクター属に属する酢酸菌)の生成物である水溶性ヘテロ多糖類を、好ましくは、水溶性ヘテロ多糖類AX-1及び/又は水溶性ヘテロ多糖類AM-2、またはそれら多糖類の分解生成物(例えば、低分子化物)を有効成分として含有することを特徴とする軟骨保護組成物を提供するものである。本組成物は、飲食品及び/又は医薬品として使用することもできる。
PCT/JP2008/055591 2007-03-26 2008-03-25 軟骨保護組成物 WO2008117801A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-078330 2007-03-26
JP2007078330 2007-03-26

Publications (1)

Publication Number Publication Date
WO2008117801A1 true WO2008117801A1 (ja) 2008-10-02

Family

ID=39788535

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/055591 WO2008117801A1 (ja) 2007-03-26 2008-03-25 軟骨保護組成物

Country Status (1)

Country Link
WO (1) WO2008117801A1 (ja)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07188035A (ja) * 1993-12-24 1995-07-25 Kureha Chem Ind Co Ltd 軟骨保護剤
JP2004002375A (ja) * 2002-04-10 2004-01-08 Koichi Okuya 軟骨細胞増殖促進薬及び軟骨障害の予防又は治療薬
JP2007138061A (ja) * 2005-11-21 2007-06-07 Mitsukan Group Honsha:Kk 酸性ヘテロ多糖類ax−1

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07188035A (ja) * 1993-12-24 1995-07-25 Kureha Chem Ind Co Ltd 軟骨保護剤
JP2004002375A (ja) * 2002-04-10 2004-01-08 Koichi Okuya 軟骨細胞増殖促進薬及び軟骨障害の予防又は治療薬
JP2007138061A (ja) * 2005-11-21 2007-06-07 Mitsukan Group Honsha:Kk 酸性ヘテロ多糖類ax−1

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
COUSO R.O. ET AL.: "A xanthan-gum-like polysaccharide from Acetobacter xylinum", JOURNAL OF GENERAL MICROBIOLOGY, vol. 133, no. 8, 1987, pages 2123 - 2135, XP001320225 *
MINAKAMI H. ET AL.: "Isolation and characterization of a new polysaccharide-producing Acetobacter sp", AGRICULTURAL AND BIOLOGICAL CHEMISTRY, vol. 48, no. 10, 1984, pages 2405 - 2414 *
TAYAMA K. ET AL.: "Structure of an acidic polysaccharide from Acetobacter sp. NBI 1022", AGRICULTURAL AND BIOLOGICAL CHEMISTRY, vol. 49, no. 4, 1985, pages 959 - 966 *
VALLA S. ET AL.: "Isolation and characterization of a new extracellular polysaccharide from a cellulose-negative strain of Acetobacter xylinum", CANADIAN JOURNAL OF MICROBIOLOGY, vol. 27, no. 6, 1981, pages 599 - 603 *

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