WO2008116635A2 - Composition for the topical/dermic application of homeopathic agents - Google Patents

Composition for the topical/dermic application of homeopathic agents Download PDF

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Publication number
WO2008116635A2
WO2008116635A2 PCT/EP2008/002372 EP2008002372W WO2008116635A2 WO 2008116635 A2 WO2008116635 A2 WO 2008116635A2 EP 2008002372 W EP2008002372 W EP 2008002372W WO 2008116635 A2 WO2008116635 A2 WO 2008116635A2
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Prior art keywords
composition
homeopathic
application
composition according
cream
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PCT/EP2008/002372
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German (de)
French (fr)
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WO2008116635A3 (en
Inventor
Angelika-Regine Dietz
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Biologische Heilmittel Heel Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of WO2008116635A2 publication Critical patent/WO2008116635A2/en
Publication of WO2008116635A3 publication Critical patent/WO2008116635A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm

Definitions

  • composition for the topical dermal application of homeopathic remedies Composition for the topical dermal application of homeopathic remedies
  • the invention relates to a composition for the use of homeopathic agents in a base suitable for topical dermal application, in which the agent is contained in liquid or in solution form within nanosomes or microsomes in the base.
  • the invention is based on the finding that substances which are not or only slightly effective on the skin by themselves, when applied to certain skin sites and especially over a long period of time when released from nanosomes and microsomes, which allow an increased concentration of the agents in a base, Surprisingly, a previously unused effect can unfold.
  • Prior art is not known.
  • the object of the invention can therefore be seen in making available known natural remedies, in particular known homeopathic medicines for further alternative forms of treatment.
  • compositions for use of homeopathic agents in a base suitable for topical dermal application in which the agent is contained in liquid or in solution form within nanosomes or microsomes in the base.
  • Homeopathic remedies as far as liquid, are generally potentiated in physiological saline and can be used in the composition in just this form. An external effect or application of these funds is not known.
  • composition according to the invention on the skin is attributed to the fact that the properties of the skin and of the underlying tissue at special neurological trigger points, at acupuncture points and along certain medial Ridiane special in particular differs the anatomy of the skin, for example, the skin resistance is lower, and thus more sensitive to the absorption of substances and information can be.
  • the composition according to the invention is therefore preferably used on the special skin areas mentioned.
  • the surface-physically stabilized nano- and microsomes slowly release their contents through the body heat on skin contact. This is already known from applications on creams. New is the application of homeopathic potentiated agents in nano- and microsomes including the use in natural remedies used minerals, such as the Schüssler salts.
  • the effect of the funds is very well supported by the fact that both the onset of action and the duration of action are very well controlled by nano- and microsome technology. Even after the immediate release, an extension of the effectiveness may result from the embedding in fat.
  • the invention thus provides a topical dermal composition, in particular an ointment or cream, which can be applied very well to neurological triggering zones along painful pathways or meridians.
  • the composition of the invention exhibits its optimum effect. It is therefore a stimulating agent, wherein the stimulation in the sense of stimulation or reassurance can be done.
  • the composition also includes a "wellness cream" to increase the physical well-being.
  • Schüssler salts can also be used very advantageously in aqueous solutions and various dilutions-also mixed with one another or with other salts or homeopathic agents.
  • Schüssler salts are given in a classic tablet form pressed with milk sugar. However, they are also available in drop form and in this dosage form they can be incorporated directly into the nano- or microsomes for the composition to be applied to the skin.
  • Schüsslersalze come for example in question: Schüsslersalz No. 2 - for the stabilization and support of tissue, ie, inter alia, to strengthen the connective tissue; Schüssler's salt No. 7 - for relaxation; Schüssler's salt No. 11 - against acne.
  • the person skilled in the art knows numerous remedies influencing the overall condition, the condition of the nerves, skin and organs, as well as relaxing and pain-relieving remedies of homeopathic and / or naturopathic nature which are very advantageous in the composition according to the invention for treatment at said meridians, acupuncture and trigger points or can be used along the pain pathways.
  • the basis for the topical dermal application may be any known basis, e.g. an ointment base, a cream base, a gel, a paste or a thickened tincture.
  • the base is an oil-in-water emulsion or a water-in-oil emulsion.
  • the nanosomes or microsomes are incorporated as known per se in the art.
  • Topical dermal applications are often referred to as transdermal applications. Both terms should be considered equivalent.
  • composition may further contain conventional pharmaceutical or cosmetic adjuncts and additives. These include in particular: fragrances, emulsifiers, stabilizers, thickeners, preservatives.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to a composition, especially in the form of an ointment or cream, for the application of homeopathic agents, wherein the agent is contained in the ointment or cream base encapsulated in nanosomes or microsomes in liquid or dissolved form. The aim of the invention is to apply said composition on neurological trigger zones along pain pathways or meridians. When applied in this way, the composition develops its optimum action in the sense of a manipulating agent, the manipulation being of the stimulating or soothing type ('wellness cream') and should all in all promote the physical well-being.

Description

Zusammensetzung zur topisch-dermalen Anwendung von homöopathischen Mitteln Composition for the topical dermal application of homeopathic remedies
Die Erfindung betrifft eine Zusammensetzung zur Anwendung von homöopathischen Mitteln in einer für topisch-dermale Applikation geeigneten Grundlage, bei welcher das Mittel in flüssiger oder in Lösung gebrachter Form innerhalb von Nanosomen oder Mikrosomen in der Grundlage enthalten ist.The invention relates to a composition for the use of homeopathic agents in a base suitable for topical dermal application, in which the agent is contained in liquid or in solution form within nanosomes or microsomes in the base.
Die Erfindung beruht auf der Erkenntnis, dass Stoffe, die über die Haut an sich nicht oder wenig wirksam sind, bei Anwendung an bestimmten Hautstellen und insbesondere über längere Zeit bei Freigabe aus Nanosomen und Mikrosomen, die eine erhöhte Konzentration der Mittel in einer Grundlage ermöglichen, überraschenderweise eine bislang nicht genutzte Wirkung entfalten können. Stand der Technik hierzu ist nicht bekannt.The invention is based on the finding that substances which are not or only slightly effective on the skin by themselves, when applied to certain skin sites and especially over a long period of time when released from nanosomes and microsomes, which allow an increased concentration of the agents in a base, Surprisingly, a previously unused effect can unfold. Prior art is not known.
Die Aufgabe der Erfindung kann daher darin gesehen werden, bekannte Naturheilmedikamente, insbesondere bekannte homöopathische Medikamente für weitere alternative Behandlungsformen zugänglich zu machen.The object of the invention can therefore be seen in making available known natural remedies, in particular known homeopathic medicines for further alternative forms of treatment.
Die Aufgabe wird gelöst durch eine Zusammensetzung zur Anwendung von homöopathischen Mitteln in einer für topisch-dermale Applikation geeigneten Grundlage, bei welcher das Mittel in flüssiger oder in Lösung gebrachter Form innerhalb von Nanosomen oder Mikrosomen in der Grundlage enthalten ist.The object is achieved by a composition for use of homeopathic agents in a base suitable for topical dermal application, in which the agent is contained in liquid or in solution form within nanosomes or microsomes in the base.
Die Verwendung von Nanosomen, um Inhaltsstoffe in eine kosmetische Grundlage einzubringen, bzw. aus dieser heraus abzugeben, ist unter anderem aus der DE 296 11 013 U1 bekannt.The use of nanosomes in order to introduce ingredients into or out of a cosmetic base is known inter alia from DE 296 11 013 U1.
Homöopathische Mittel liegen - soweit flüssig - im Allgemeinen in physiologischer Kochsalzlösung potenziert vor und können in der Zusammensetzung in eben dieser Form verwendet werden. Eine äußerliche Wirkung bzw. Anwendung dieser Mittel ist nicht bekannt.Homeopathic remedies, as far as liquid, are generally potentiated in physiological saline and can be used in the composition in just this form. An external effect or application of these funds is not known.
Die Wirkung der erfindungsgemäßen Zusammensetzung auf der Haut wird darauf zurückgeführt, dass die Eigenschaften der Haut und des darunter liegenden Gewebes an besonderen neurologischen Triggerpunkten, an Akupunkturpunkten und entlang bestimmter Me- ridiane besondere sind insbesondere unterscheidet sich die Anatomie der Haut, z.B. ist der Hautwiderstand geringer, und somit empfindlicher für die Aufnahme von Stoffen und Informationen seien können. Bevorzugt wird die erfindungsgemäße Zusammensetzung daher auf den genannten besonderen Hautbereichen verwendet.The effect of the composition according to the invention on the skin is attributed to the fact that the properties of the skin and of the underlying tissue at special neurological trigger points, at acupuncture points and along certain medial Ridiane special in particular differs the anatomy of the skin, for example, the skin resistance is lower, and thus more sensitive to the absorption of substances and information can be. The composition according to the invention is therefore preferably used on the special skin areas mentioned.
Die oberflächenphysikalisch stabilisierten Nano- und Mikrosomen geben ihren Inhalt erst langsam durch die Körperwärme bei Hautkontakt ab. Dies ist aus Anwendungen an Cremes bereits bekannt. Neu ist die Anwendung homöopathischer potenzierter Mittel in Nano- und Mikrosomen einschließlich der Anwendung in der Naturheilkunde genutzter Mineralien, wie der Schüsslersalze. Die Wirkung der Mittel wird sehr gut dadurch unterstützt, dass sowohl der Wirkungseintritt als auch die Wirkungsdauer sehr gut über die Nano- und Mikrosomentechnik steuerbar sind. Auch nach der unmittelbaren Freisetzung kann sich eine Verlängerung der Wirksamkeit durch die Einbettung in Fett ergeben.The surface-physically stabilized nano- and microsomes slowly release their contents through the body heat on skin contact. This is already known from applications on creams. New is the application of homeopathic potentiated agents in nano- and microsomes including the use in natural remedies used minerals, such as the Schüssler salts. The effect of the funds is very well supported by the fact that both the onset of action and the duration of action are very well controlled by nano- and microsome technology. Even after the immediate release, an extension of the effectiveness may result from the embedding in fat.
Die Erfindung stellt damit eine topisch-dermale Zusammensetzung, insbesondere eine Salbe oder Creme bereit, die sehr gut auf neurologischen Triggerzonen, entlang von Schmerzbahnen oder Meridianen angewendet werden kann. Bei dieser Anwendung entfaltet die erfindungsgemäße Zusammensetzung ihre optimale Wirkung. Es handelt sich demnach um ein stimulierendes Mittel, wobei die Stimulation im Sinne einer Anregung o- der auch Beruhigung erfolgen kann.The invention thus provides a topical dermal composition, in particular an ointment or cream, which can be applied very well to neurological triggering zones along painful pathways or meridians. In this application, the composition of the invention exhibits its optimum effect. It is therefore a stimulating agent, wherein the stimulation in the sense of stimulation or reassurance can be done.
Die Zusammensetzung umfasst auch eine „Wellnesscreme" zur Steigerung des körperlichen Wohlbefindens.The composition also includes a "wellness cream" to increase the physical well-being.
Wie vorstehend beschrieben ist das flüssige oder in Lösung gebrachte Naturheilmedikament homöopatisch. Sehr vorteilhaft können auch Schüsslersalze in wässrigen Lösungen und verschiedenen Verdünnungen - auch im Gemisch untereinander oder mit anderen Salzen oder homöopathischen Mitteln - eingesetzt werden. Schüsslersalze werden klassisch in Tablettenform mit Milchzucker verpresst gegeben. Sie sind jedoch auch in Tropfenform erhältlich und in dieser Darreichungsform können sie direkt in die Nano- oder Mikrosomen für die auf der Haut anzuwendende Zusammensetzung eingebracht werden.As described above, the liquid or dissolved naturopathic medicine is homeopathic. Schüssler salts can also be used very advantageously in aqueous solutions and various dilutions-also mixed with one another or with other salts or homeopathic agents. Schüssler salts are given in a classic tablet form pressed with milk sugar. However, they are also available in drop form and in this dosage form they can be incorporated directly into the nano- or microsomes for the composition to be applied to the skin.
Als Schüsslersalze kommen beispielsweise in Frage: Schüsslersalz Nr. 2 - für die Stabilisierung und Stützung von Gewebe, d.h. unter anderem zur Stärkung des Bindegewebes; Schüsslersalz Nr. 7 - zur Entspannung; Schüsslersalz Nr. 11 - gegen Akne. Der Fachmann kennt zahlreiche das Gesamtbefinden, den Nerven- Haut- und Organzustand usw. beeinflussende Mittel, sowie entspannende und schmerzlösende Mittel homöopathischer und/oder naturheilkundlicher Art, die sehr vorteilhaft in der erfindungsgemäßen Zusammensetzung zur Behandlung an den genannten Meridianen, Akupunktur- und Triggerpunkten oder entlang der Schmerzbahnen eingesetzt werden können.As Schüsslersalze come for example in question: Schüsslersalz No. 2 - for the stabilization and support of tissue, ie, inter alia, to strengthen the connective tissue; Schüssler's salt No. 7 - for relaxation; Schüssler's salt No. 11 - against acne. The person skilled in the art knows numerous remedies influencing the overall condition, the condition of the nerves, skin and organs, as well as relaxing and pain-relieving remedies of homeopathic and / or naturopathic nature which are very advantageous in the composition according to the invention for treatment at said meridians, acupuncture and trigger points or can be used along the pain pathways.
Die Grundlage für die topisch-dermale Anwendung kann grundsätzlich jede bekannte Grundlage sein, z.B. eine Salbengrundlage, eine Cremegrundlage, ein Gel, eine Paste oder eine angedickte Tinktur. Vorzugsweise ist die Grundlage eine öl-in-Wasser-Emulsion oder eine Wasser-in-öl-Emulsion. Innerhalb der Grundlage sind die Nanosomen oder Mikrosomen wie an sich im Stand der Technik bekannt eingearbeitet. Topisch-dermale Anwendungen werden häufig auch als transdermale Anwendungen bezeichnet. Beide Begriffe sind als gleichwertig anzusehen.Basically, the basis for the topical dermal application may be any known basis, e.g. an ointment base, a cream base, a gel, a paste or a thickened tincture. Preferably, the base is an oil-in-water emulsion or a water-in-oil emulsion. Within the framework, the nanosomes or microsomes are incorporated as known per se in the art. Topical dermal applications are often referred to as transdermal applications. Both terms should be considered equivalent.
Die Zusammensetzung kann weiterhin übliche pharmazeutische oder kosmetische Hilfsund Zusatzstoffe enthalten. Hierunter fallen insbesondere: Duftstoffe, Emulgatoren, Stabilisatoren, Verdickungsmittel, Konservierungsmittel. The composition may further contain conventional pharmaceutical or cosmetic adjuncts and additives. These include in particular: fragrances, emulsifiers, stabilizers, thickeners, preservatives.

Claims

Patentansprüche: claims:
1. Zusammensetzung zur Anwendung von homöopathischen Mitteln in einer für topisch- dermale Applikation geeigneten Grundlage, bei welcher das homöopathische Mittel in flüssiger oder in Lösung gebrachter Form innerhalb von Nanosomen oder Mikrosomen in der Grundlage enthalten ist.A composition for use of homeopathic remedies in a base suitable for topical dermal application, wherein the homeopathic agent is contained in liquid or in solution form within nanosomes or microsomes in the base.
2. Zusammensetzung nach Anspruch 1 , dadurch gekennzeichnet, dass das homöopathische Mittel ein oder mehrere Schüsslersalze in Lösung enthält.2. Composition according to claim 1, characterized in that the homeopathic agent contains one or more Schüsslersalze in solution.
3. Zusammensetzung nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass die Grundlage eine öl-in-Wasser-Emulsion oder eine Waller-in-öl-Emulsion ist.3. Composition according to claim 1 or 2, characterized in that the basis is an oil-in-water emulsion or a Waller-in-oil emulsion.
4. Zusammensetzung nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, dass zusätzlich übliche kosmetische Hilfs- und Zusatzstoffe enthalten sind.4. The composition according to any one of claims 1 to 3, characterized in that in addition conventional cosmetic auxiliaries and additives are included.
5. Verwendung der Zusammensetzung nach einem der Ansprüche 1 bis 4 auf neurologischen Triggerzonen, an Akupunkturpunkten, entlang von Schmerzbahnen oder Meridianen. 5. Use of the composition according to one of claims 1 to 4 on neurological trigger zones, on acupuncture points, along pain pathways or meridians.
PCT/EP2008/002372 2007-03-26 2008-03-26 Composition for the topical/dermic application of homeopathic agents WO2008116635A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200710015044 DE102007015044A1 (en) 2007-03-26 2007-03-26 Composition for the topical dermal application of homeopathic remedies
DE102007015044.1 2007-03-26

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WO2008116635A2 true WO2008116635A2 (en) 2008-10-02
WO2008116635A3 WO2008116635A3 (en) 2009-01-15

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29611013U1 (en) * 1996-06-24 1997-10-23 Goldwell Gmbh Cosmetic products
WO2004075901A2 (en) * 2003-02-25 2004-09-10 Mesko Charles A Compositon for increasing levels of hormones and a method for preparation of said composition
WO2005084681A1 (en) * 2004-03-01 2005-09-15 Mesko Charles A Composition for increasing levels of hormones and a method for preparation of said composition
EP1728519A2 (en) * 2005-06-01 2006-12-06 Siegfried Natterer Polar supporting and broad-band resonant preparation
DE202006015160U1 (en) * 2006-10-04 2007-08-09 Decher, Bettina Combination of all 12 Schüssler salts

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2113309B1 (en) * 1996-02-27 1999-01-01 Guerrero Jose Felipe Galian LIPOSOMES ENCAPSULATING POTENTIATED SUBSTANCES.

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29611013U1 (en) * 1996-06-24 1997-10-23 Goldwell Gmbh Cosmetic products
WO2004075901A2 (en) * 2003-02-25 2004-09-10 Mesko Charles A Compositon for increasing levels of hormones and a method for preparation of said composition
WO2005084681A1 (en) * 2004-03-01 2005-09-15 Mesko Charles A Composition for increasing levels of hormones and a method for preparation of said composition
EP1728519A2 (en) * 2005-06-01 2006-12-06 Siegfried Natterer Polar supporting and broad-band resonant preparation
DE202006015160U1 (en) * 2006-10-04 2007-08-09 Decher, Bettina Combination of all 12 Schüssler salts

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WO2008116635A3 (en) 2009-01-15

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