WO2008114736A1 - Body tissue filling material and method for production thereof - Google Patents

Body tissue filling material and method for production thereof Download PDF

Info

Publication number
WO2008114736A1
WO2008114736A1 PCT/JP2008/054772 JP2008054772W WO2008114736A1 WO 2008114736 A1 WO2008114736 A1 WO 2008114736A1 JP 2008054772 W JP2008054772 W JP 2008054772W WO 2008114736 A1 WO2008114736 A1 WO 2008114736A1
Authority
WO
WIPO (PCT)
Prior art keywords
filling material
body tissue
porous carrier
tissue filling
hyaluronic acid
Prior art date
Application number
PCT/JP2008/054772
Other languages
French (fr)
Japanese (ja)
Inventor
Tomoaki Tamura
Yasuharu Hakamatsuka
Toshie Tsuchiya
Shigeyuki Wakitani
Original Assignee
Olympus Corporation
Japan As Represented By National Institute Of Health Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Corporation, Japan As Represented By National Institute Of Health Sciences filed Critical Olympus Corporation
Priority to US12/529,622 priority Critical patent/US20100278877A1/en
Priority to EP08722168A priority patent/EP2127688A4/en
Publication of WO2008114736A1 publication Critical patent/WO2008114736A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Disclosed are: a body tissue filling material having excellent adhesion property and excellent restoration ability; and a method for producing the body tissue filling material in a simple manner. Specifically disclosed are: a body tissue filling material comprising a porous carrier comprising gelatin and sulfated hyaluronic acid coated on the surface of the porous carrier; and a method for producing a body tissue filling material, which involves the following steps: a step (S3) for dropping a solution of sulfated hyaluronic acid onto a porous carrier comprising gelatin to cause the impregnation of the porous carrier with the solution of sulfated hyaluronic acid; a step (S4) for freezing the porous carrier impregnated with the solution of sulfated hyaluronic acid; and a step (S5) for drying the frozen porous carrier.
PCT/JP2008/054772 2007-03-16 2008-03-14 Body tissue filling material and method for production thereof WO2008114736A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/529,622 US20100278877A1 (en) 2007-03-16 2008-03-14 Body tissue filling material and method for production thereof
EP08722168A EP2127688A4 (en) 2007-03-16 2008-03-14 Body tissue filling material and method for production thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-069160 2007-03-16
JP2007069160A JP5088864B2 (en) 2007-03-16 2007-03-16 Biological tissue filling material and manufacturing method thereof

Publications (1)

Publication Number Publication Date
WO2008114736A1 true WO2008114736A1 (en) 2008-09-25

Family

ID=39765844

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/054772 WO2008114736A1 (en) 2007-03-16 2008-03-14 Body tissue filling material and method for production thereof

Country Status (4)

Country Link
US (1) US20100278877A1 (en)
EP (1) EP2127688A4 (en)
JP (1) JP5088864B2 (en)
WO (1) WO2008114736A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010010904A (en) 2008-04-04 2010-11-04 Univ Utah Res Found Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof.
AU2012230822A1 (en) 2011-03-23 2013-11-07 University Of Utah Research Foundation Methods for treating or preventing urological inflammation
EP2981556A4 (en) 2013-04-02 2016-11-30 Univ California Ethylsulfonated hyaluronic acid biopolymers and methods of use thereof
US11337994B2 (en) 2016-09-15 2022-05-24 University Of Utah Research Foundation In situ gelling compositions for the treatment or prevention of inflammation and tissue damage

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996010426A1 (en) 1994-09-30 1996-04-11 Yamanouchi Pharmaceutical Co., Ltd. Osteoplastic graft
JPH09510493A (en) * 1994-03-23 1997-10-21 フィディア・アドヴァンスト・バイオポリマーズ・ソシエタ・ア・レスポンサビリタ・リミタータ Novel heparin-like sulfated polysaccharide
WO2003011353A1 (en) 2001-07-30 2003-02-13 Japan Tissue Engineering Co., Ltd Tissue regenerating base material, implanting material and method of producing the same
JP2003245338A (en) * 2002-02-26 2003-09-02 Kyocera Corp Articular cartilage restorative material
WO2006037592A1 (en) * 2004-10-08 2006-04-13 Fidia Advanced Biopolymers S.R.L. Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions
WO2007137674A1 (en) * 2006-05-31 2007-12-06 Fidia Farmaceutici S.P.A. Sulphated hyaluronic acid for treating degenerative osteoarthritis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE229038T1 (en) * 1997-04-04 2002-12-15 Fidia Advanced Biopolymers Srl N-SULFATED HYALURONIC ACID COMPOUNDS, THEIR DERIVATIVES AND METHOD FOR THEIR PRODUCTION
ITPD980149A1 (en) * 1998-06-17 1999-12-17 Fidia Advanced Biopolymers Srl THREE-DIMENSIONAL PROSTHESES INCLUDING HYALURONIC ACID DERIVATIVES TO REPAIR OR REBUILD DAMAGED TISSUES AND PROCESS FOR THE
JP3536295B2 (en) * 1999-01-21 2004-06-07 ニプロ株式会社 Sutureable tissue regeneration induced adhesion prevention membrane
DE10053053A1 (en) * 2000-10-19 2002-05-16 Knoell Hans Forschung Ev Pharmaceutical formulations for the inhibition of inflammatory arthritis
KR101135937B1 (en) * 2003-09-12 2012-04-18 세이가가쿠 고교 가부시키가이샤 Polysaccharide pseudo-sponge
US20060154894A1 (en) * 2004-09-15 2006-07-13 Massachusetts Institute Of Technology Biologically active surfaces and methods of their use

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09510493A (en) * 1994-03-23 1997-10-21 フィディア・アドヴァンスト・バイオポリマーズ・ソシエタ・ア・レスポンサビリタ・リミタータ Novel heparin-like sulfated polysaccharide
WO1996010426A1 (en) 1994-09-30 1996-04-11 Yamanouchi Pharmaceutical Co., Ltd. Osteoplastic graft
WO2003011353A1 (en) 2001-07-30 2003-02-13 Japan Tissue Engineering Co., Ltd Tissue regenerating base material, implanting material and method of producing the same
JP2003245338A (en) * 2002-02-26 2003-09-02 Kyocera Corp Articular cartilage restorative material
WO2006037592A1 (en) * 2004-10-08 2006-04-13 Fidia Advanced Biopolymers S.R.L. Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions
WO2007137674A1 (en) * 2006-05-31 2007-12-06 Fidia Farmaceutici S.P.A. Sulphated hyaluronic acid for treating degenerative osteoarthritis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HAMILTON D.W. ET AL.: "The response of primary articular chondrocytes to micrometric surface topography and sulphated hyaluronic acid-based matrices", CELL BIOLOGY INTERNATIONAL, vol. 29, no. 8, 2005, pages 605 - 615, XP005012056 *
See also references of EP2127688A4 *

Also Published As

Publication number Publication date
EP2127688A4 (en) 2013-01-02
EP2127688A1 (en) 2009-12-02
JP2008228812A (en) 2008-10-02
JP5088864B2 (en) 2012-12-05
US20100278877A1 (en) 2010-11-04

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