WO2008111919A3 - A novel combination of water-soluble forms of coenzyme q10 and l-carnitine, process of production and use - Google Patents

A novel combination of water-soluble forms of coenzyme q10 and l-carnitine, process of production and use Download PDF

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Publication number
WO2008111919A3
WO2008111919A3 PCT/SI2008/000012 SI2008000012W WO2008111919A3 WO 2008111919 A3 WO2008111919 A3 WO 2008111919A3 SI 2008000012 W SI2008000012 W SI 2008000012W WO 2008111919 A3 WO2008111919 A3 WO 2008111919A3
Authority
WO
WIPO (PCT)
Prior art keywords
coenzyme
carnitine
water
mixture
novel combination
Prior art date
Application number
PCT/SI2008/000012
Other languages
French (fr)
Other versions
WO2008111919A2 (en
Inventor
Mirko Prosek
Marko Prosek
Alenka Golc-Wondra
Janko Zmitek
Original Assignee
Valens Int D O O
Mirko Prosek
Marko Prosek
Alenka Golc-Wondra
Janko Zmitek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valens Int D O O, Mirko Prosek, Marko Prosek, Alenka Golc-Wondra, Janko Zmitek filed Critical Valens Int D O O
Publication of WO2008111919A2 publication Critical patent/WO2008111919A2/en
Publication of WO2008111919A3 publication Critical patent/WO2008111919A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A61K8/355—Quinones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The object of this invention is a novel combination or mixture of water-soluble forms of coenzyme Q10 and L-carnitine, as well as a process of preparing mixtures and products based on this mixture, and the use of mixtures and products based on this mixture. In the novel combination of coenzyme Q10 and L-carnitine according to the invention, the coenzyme Q10, in a suitable form having enhanced water solubility, forms a mixture with L-carnitine. The coenzyme Q10 and L-carnitine are in optional ratios, preferably in a weight ratio within the range of 1 :200 to 10:1, more preferably within the range of 1 :1 to 1 :100. The combination of coenzyme Q10 and L-carnitine is solid or in the form of a solution or suspension in water or an aqueous medium; it can be pure or it comprises added excipients and/or bioactive substances. The combination of coenzyme Q10 and L-carnitine according to the invention is used in the preparation of pharmaceuticals, nutritional products, and cosmetics, as additive, either to the premix or separately.
PCT/SI2008/000012 2007-03-15 2008-02-27 A novel combination of water-soluble forms of coenzyme q10 and l-carnitine, process of production and use WO2008111919A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SIP-200700060 2007-03-15
SI200700060A SI22465B (en) 2007-03-15 2007-03-15 New combination of water soluble forms of coenzyme q10 and l-carnitin, procedure of preparation and application

Publications (2)

Publication Number Publication Date
WO2008111919A2 WO2008111919A2 (en) 2008-09-18
WO2008111919A3 true WO2008111919A3 (en) 2009-02-05

Family

ID=39760234

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SI2008/000012 WO2008111919A2 (en) 2007-03-15 2008-02-27 A novel combination of water-soluble forms of coenzyme q10 and l-carnitine, process of production and use

Country Status (2)

Country Link
SI (1) SI22465B (en)
WO (1) WO2008111919A2 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030129177A1 (en) * 2000-04-04 2003-07-10 Sigma-Tau Healthscience S.P.A. Dietary supplement energy-providing to skeletal muscles and protecting the cardiovascular tract
EP1681053A1 (en) * 2003-10-31 2006-07-19 Kaneka Corporation Composition containing reduced coenzyme q
WO2006110924A2 (en) * 2005-04-14 2006-10-19 Jarrow Formulas, Inc. Dietary supplement formulations for improved delivery of coenzyme q10 and methods of administration
US20060269535A1 (en) * 2005-05-31 2006-11-30 Naidu A S Metallo-lactoferrin-coenzyme compositions for trigger and release of bioenergy
US20060292134A1 (en) * 2005-06-22 2006-12-28 Sidney Stohs Composition for enhancing cellular energy
US20070085059A1 (en) * 2004-02-23 2007-04-19 Texas A&M University System Bioactive Complexes Compositions and Methods of Use Thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030129177A1 (en) * 2000-04-04 2003-07-10 Sigma-Tau Healthscience S.P.A. Dietary supplement energy-providing to skeletal muscles and protecting the cardiovascular tract
EP1681053A1 (en) * 2003-10-31 2006-07-19 Kaneka Corporation Composition containing reduced coenzyme q
US20070085059A1 (en) * 2004-02-23 2007-04-19 Texas A&M University System Bioactive Complexes Compositions and Methods of Use Thereof
WO2006110924A2 (en) * 2005-04-14 2006-10-19 Jarrow Formulas, Inc. Dietary supplement formulations for improved delivery of coenzyme q10 and methods of administration
US20060269535A1 (en) * 2005-05-31 2006-11-30 Naidu A S Metallo-lactoferrin-coenzyme compositions for trigger and release of bioenergy
US20060292134A1 (en) * 2005-06-22 2006-12-28 Sidney Stohs Composition for enhancing cellular energy

Also Published As

Publication number Publication date
WO2008111919A2 (en) 2008-09-18
SI22465B (en) 2010-10-29
SI22465A (en) 2008-10-31

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