WO2008109686A8 - Non- infectious recombinant virus-like particles and their pharmaceutical applications - Google Patents
Non- infectious recombinant virus-like particles and their pharmaceutical applications Download PDFInfo
- Publication number
- WO2008109686A8 WO2008109686A8 PCT/US2008/055936 US2008055936W WO2008109686A8 WO 2008109686 A8 WO2008109686 A8 WO 2008109686A8 US 2008055936 W US2008055936 W US 2008055936W WO 2008109686 A8 WO2008109686 A8 WO 2008109686A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hepatitis
- virus
- vlps
- interferons
- vlp
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24223—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24241—Use of virus, viral particle or viral elements as a vector
- C12N2770/24243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32111—Aphthovirus, e.g. footandmouth disease virus
- C12N2770/32122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2007108037 | 2007-03-05 | ||
RU2007108037 | 2007-03-05 | ||
RU2007138092/13A RU2007138092A (en) | 2007-10-16 | 2007-10-16 | NON-INFECTIOUS RECOMBINANT PSEUDOVIRIONES OF THE HEPATITIS VIRUS C "ISVAK" TM, THEIR APPLICATION AS A MEANS FOR TREATMENT AND PREVENTION OF DISEASES, SYSTEMS OF DELIVERY OF BIOLOGICALLY INACTIVE ANTIVASIS |
RU2007138092 | 2007-10-16 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2008109686A2 WO2008109686A2 (en) | 2008-09-12 |
WO2008109686A3 WO2008109686A3 (en) | 2009-03-12 |
WO2008109686A8 true WO2008109686A8 (en) | 2009-07-30 |
Family
ID=39591928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2008/055936 WO2008109686A2 (en) | 2007-03-05 | 2008-03-05 | Non- infectious recombinant virus-like particles and their pharmaceutical applications |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2008109686A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011000058A1 (en) * | 2009-07-03 | 2011-01-06 | The University Of Queensland | A method of preparation of a biological particulate structure |
EP2933331B1 (en) * | 2012-12-11 | 2019-02-20 | Takara Bio Inc. | Expression cassette |
WO2016006658A1 (en) * | 2014-07-10 | 2016-01-14 | タカラバイオ株式会社 | Production method for non-enveloped virus particles |
WO2017044890A1 (en) * | 2015-09-10 | 2017-03-16 | Academia Sinica | Bird flu vaccine combination comprising virus-like particles and novel adjuvants |
AU2020395091A1 (en) * | 2019-12-03 | 2022-07-28 | The Council Of The Queensland Institute Of Medical Research | Defective interfering particles |
CN111303251B (en) * | 2020-02-25 | 2021-07-30 | 中国农业科学院兰州兽医研究所 | Method for in-vitro assembly of foot-and-mouth disease virus-like particles and application thereof |
CN117050158B (en) * | 2023-10-10 | 2023-12-29 | 云南农业大学 | Application of red mouth gull IFN-gamma gene and recombinant protein encoded by same |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1288073C (en) * | 1985-03-07 | 1991-08-27 | Paul G. Ahlquist | Rna transformation vector |
US7049428B1 (en) * | 1998-03-04 | 2006-05-23 | Washington University | HCV variants |
WO1998050071A1 (en) * | 1997-05-01 | 1998-11-12 | Chiron Corporation | Use of virus-like particles as adjuvants |
AU2003227380A1 (en) * | 2003-01-05 | 2004-07-29 | Obschestvo S Ogranichennoi Otvetstvennostiju "Genno-Inzhenernye Tekhnologii 2000" | Complementation method for producing rna-containing virus-like particles of hepatotropic viruses |
WO2005005614A2 (en) * | 2003-07-03 | 2005-01-20 | Pecos Labs, Inc. | Combined b-cell and t-cell epitopes on vlp for improved vaccines |
CA2544240A1 (en) * | 2003-07-22 | 2005-02-17 | Cytos Biotechnology Ag | Cpg-packaged liposomes |
-
2008
- 2008-03-05 WO PCT/US2008/055936 patent/WO2008109686A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2008109686A2 (en) | 2008-09-12 |
WO2008109686A3 (en) | 2009-03-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2008109686A8 (en) | Non- infectious recombinant virus-like particles and their pharmaceutical applications | |
Zhang et al. | Effects of astragalus polysaccharide on the immune response to foot-and-mouth disease vaccine in mice | |
MX2007003171A (en) | Virus-like particles comprising a fusion protein of the coat protein of ap205 and an antigenic polypeptide. | |
RU2008106445A (en) | VIRUS-LIKE BODIES (PARTICLES) AS ANTI-PARAMYXOVIRUS VACCINE | |
ATE447967T1 (en) | PACKAGING OF IMMUNO-STIMULATIVE CPG IN VIRUS-LIKE PARTICLES: PRODUCTION METHOD AND USE | |
JP2015501840A5 (en) | ||
WO2008034388A8 (en) | Virus-like particles of capsid proteins from human papillomavirus type 16/58/18/6/11 and the method for preparation and the uses thereof | |
BR112014015016A8 (en) | HOMODIMERIC PROTEIN OF TWO IDENTICAL AMINO ACID CHAINS, AMINO ACID CHAIN, NUCLEIC ACID MOLECULE, PHARMACEUTICAL COMPOSITION, HOST CELL, METHOD OF PREPARATION OF A HOMODIMERIC PROTEIN, METHOD FOR PREPARING A VACCINE, VACCINE AND METHOD OF TREATMENT OR PREVENTION | |
CN102166356A (en) | Application of alpha-mannatide as vaccine adjuvant and vaccine preparation prepared using same | |
RU2019107976A (en) | VACCINE COMPOSITION | |
Krishnaveni | A review on transfer factor an immune modulator | |
JP2010506926A5 (en) | ||
CN103687942A (en) | Virus-like particles and process for preparing same | |
WO2003090687A3 (en) | Using heat shock proteins to increase immune response | |
DE60332377D1 (en) | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES MEDIATED BY THE HUMANE PAPILLOMA VIRUS | |
CN102127554B (en) | Japanese encephalitis particle vaccine and preparation method and application thereof | |
CN106421774B (en) | PreS1 is used to prepare hepatitis B vaccine and treats the purposes of chronic hepatitis B | |
TW200509964A (en) | VP1 of foot-and-mouth disease virus | |
CN102199217B (en) | Hepatitis B virus multi-epitope fusion protein and preparation method and application thereof | |
CN103893748A (en) | Novel vaccine for hand-foot-and-mouth disease and a preparation method thereof | |
CN102000330B (en) | Nucleic acid vaccine adjuvant and construction method thereof | |
CN104056266B (en) | Mopterin adjuvant and the vaccine containing mopterin adjuvant | |
CN101693885B (en) | Anti-HBV (hepatitis B Virus) nicotine medicine composition | |
DE60121462D1 (en) | NUCLEIC ACID VACCINE CONSISTING OF A FUSION PROTEIN THAT HAS AN ADJUVANCE SEQUENCE OF A PLANT VIRUS SHELL PROTEIN | |
RU2010121252A (en) | COMPOSITION FOR TREATMENT OF HEPATITIS C (OPTIONS), METHOD FOR PREPARING COMPOSITION FOR TREATMENT OF HEPATITIS C (OPTIONS) AND METHOD FOR TREATMENT OF HEPATITIS C (OPTIONS) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 08731455 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase in: |
Ref country code: DE |
|
WPC | Withdrawal of priority claims after completion of the technical preparations for international publication |
Ref document number: 2007108037 Country of ref document: RU Date of ref document: 20090902 Free format text: WITHDRAWN AFTER TECHNICAL PREPARATION FINISHED |
|
122 | Ep: pct app. not ent. europ. phase |
Ref document number: 08731455 Country of ref document: EP Kind code of ref document: A2 |