WO2008093647A1 - Microréseau, son procédé de fabrication, et procédé de détection d'une interaction entre une molécule organique et une substance active - Google Patents
Microréseau, son procédé de fabrication, et procédé de détection d'une interaction entre une molécule organique et une substance active Download PDFInfo
- Publication number
- WO2008093647A1 WO2008093647A1 PCT/JP2008/051227 JP2008051227W WO2008093647A1 WO 2008093647 A1 WO2008093647 A1 WO 2008093647A1 JP 2008051227 W JP2008051227 W JP 2008051227W WO 2008093647 A1 WO2008093647 A1 WO 2008093647A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- microarray
- organic molecule
- interaction
- active substance
- immobilized
- Prior art date
Links
- 238000002493 microarray Methods 0.000 title abstract 7
- 239000013543 active substance Substances 0.000 title abstract 4
- 230000003993 interaction Effects 0.000 title abstract 4
- 238000001514 detection method Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000758 substrate Substances 0.000 abstract 3
- 238000004458 analytical method Methods 0.000 abstract 1
- 230000005540 biological transmission Effects 0.000 abstract 1
- 230000009878 intermolecular interaction Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000005556 structure-activity relationship Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/3581—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using far infrared light; using Terahertz radiation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/3563—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solids; Preparation of samples therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
L'invention concerne un microréseau sur lequel est immobilisée une molécule organique, qui permet à la molécule organique d'être immobilisée sur un substrat solide dans diverses orientations et de détecter une interaction compliquée entre la molécule organique et une substance active mais n'a pas de restriction d'orientation et qui, par conséquent, peut analyser des relations structure-activité et être fabriqué de façon simple et à bas prix ; un procédé de fabrication du microréseau ; et un procédé de détection de l'interaction entre une substance active et la molécule organique à l'aide du microréseau. L'invention concerne spécifiquement un microréseau sur lequel est immobilisée une molécule organique utilisée pour la détection de l'interaction entre la molécule organique et la substance active. Le microréseau comprend un substrat (A), un support organique (B) immobilisé sur le substrat (A) par une interaction intermoléculaire, et une molécule organique (C) immobilisée sur le support organique (B). Dans un mode de réalisation préféré, une analyse est faite par la mesure à l'aide du microréseau d'au moins un élément choisi parmi la transmission, la réflexion et l'interférence d'une onde Téra-Hertz (THz).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008556090A JPWO2008093647A1 (ja) | 2007-01-31 | 2008-01-28 | マイクロアレイとその製造方法並びに有機分子と作用物質との相互作用の検出方法 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-022396 | 2007-01-31 | ||
JP2007022396 | 2007-01-31 | ||
JP2007-022380 | 2007-01-31 | ||
JP2007022380 | 2007-01-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008093647A1 true WO2008093647A1 (fr) | 2008-08-07 |
Family
ID=39673958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/051227 WO2008093647A1 (fr) | 2007-01-31 | 2008-01-28 | Microréseau, son procédé de fabrication, et procédé de détection d'une interaction entre une molécule organique et une substance active |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPWO2008093647A1 (fr) |
WO (1) | WO2008093647A1 (fr) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010190837A (ja) * | 2009-02-20 | 2010-09-02 | Kurabo Ind Ltd | logPの決定方法、および該方法に使用される二相系溶媒 |
JP2010249564A (ja) * | 2009-04-13 | 2010-11-04 | Nippon Telegr & Teleph Corp <Ntt> | 溶解性分光測定方法及び溶解性分光測定装置 |
JP2011506673A (ja) * | 2007-12-14 | 2011-03-03 | バイオティウム, インコーポレイテッド | 蛍光性化合物 |
JP2011112548A (ja) * | 2009-11-27 | 2011-06-09 | Sony Corp | 生体サンプル解析方法、生体サンプル解析装置及び生体サンプル解析プログラム |
WO2011125355A1 (fr) * | 2010-04-01 | 2011-10-13 | 株式会社村田製作所 | Procédé de mesure d'une caractéristique d'un objet à mesurer, et dispositif de détection utilisé dans ledit procédé |
CN108398400A (zh) * | 2018-01-18 | 2018-08-14 | 河南工业大学 | 利用太赫兹成像无损检测小麦中脂肪酸含量的方法 |
JP2020511652A (ja) * | 2016-12-01 | 2020-04-16 | ユニバーシティ・オブ・ソウル・インダストリー・コーオパレイション・ファウンデイションUniversity Of Seoul Industry Cooperation Foundation | テラヘルツ波を用いたdna分析方法およびdna分析装置 |
WO2020080576A1 (fr) * | 2018-10-18 | 2020-04-23 | 연세대학교 산학협력단 | Procédé permettant de prédire un changement d'absorbance au moyen d'une interaction intermoléculaire |
CN111366555A (zh) * | 2020-02-27 | 2020-07-03 | 浙江大学 | 一种耕地土壤中农膜残留的检测方法 |
WO2022029135A1 (fr) * | 2020-08-03 | 2022-02-10 | Jt International Sa | Procédé de mesure et étiquette disposée dans un article à fumer ou un emballage d'articles à fumer |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11201971A (ja) * | 1997-11-09 | 1999-07-30 | Bayer Corp | 流体試料中の分析対象物を検出する方法 |
JP2005233955A (ja) * | 2004-02-16 | 2005-09-02 | Samsung Electronics Co Ltd | 生体分子を固体基板上に非共有的に固定化する方法及びそれによって製造されるマイクロアレイ |
JP2005283143A (ja) * | 2004-03-26 | 2005-10-13 | Fuji Photo Film Co Ltd | バイオセンサー |
JP2006084422A (ja) * | 2004-09-17 | 2006-03-30 | Pentax Corp | 透過画像生成方法及び透過画像生成装置 |
WO2006137824A2 (fr) * | 2004-08-04 | 2006-12-28 | Intel Corporation | Procedes et systemes de detection d'une liaison biomoleculaire au moyen d'un rayonnement terahertz |
-
2008
- 2008-01-28 WO PCT/JP2008/051227 patent/WO2008093647A1/fr active Application Filing
- 2008-01-28 JP JP2008556090A patent/JPWO2008093647A1/ja active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11201971A (ja) * | 1997-11-09 | 1999-07-30 | Bayer Corp | 流体試料中の分析対象物を検出する方法 |
JP2005233955A (ja) * | 2004-02-16 | 2005-09-02 | Samsung Electronics Co Ltd | 生体分子を固体基板上に非共有的に固定化する方法及びそれによって製造されるマイクロアレイ |
JP2005283143A (ja) * | 2004-03-26 | 2005-10-13 | Fuji Photo Film Co Ltd | バイオセンサー |
WO2006137824A2 (fr) * | 2004-08-04 | 2006-12-28 | Intel Corporation | Procedes et systemes de detection d'une liaison biomoleculaire au moyen d'un rayonnement terahertz |
JP2006084422A (ja) * | 2004-09-17 | 2006-03-30 | Pentax Corp | 透過画像生成方法及び透過画像生成装置 |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9791450B2 (en) | 2007-12-14 | 2017-10-17 | Biotium, Inc. | Fluorescent compounds |
JP2011506673A (ja) * | 2007-12-14 | 2011-03-03 | バイオティウム, インコーポレイテッド | 蛍光性化合物 |
US9097667B2 (en) | 2007-12-14 | 2015-08-04 | Biotium, Inc. | Fluorescent compounds |
JP2015172199A (ja) * | 2007-12-14 | 2015-10-01 | バイオティウム, インコーポレイテッド | 蛍光性化合物 |
JP2010190837A (ja) * | 2009-02-20 | 2010-09-02 | Kurabo Ind Ltd | logPの決定方法、および該方法に使用される二相系溶媒 |
JP2010249564A (ja) * | 2009-04-13 | 2010-11-04 | Nippon Telegr & Teleph Corp <Ntt> | 溶解性分光測定方法及び溶解性分光測定装置 |
JP2011112548A (ja) * | 2009-11-27 | 2011-06-09 | Sony Corp | 生体サンプル解析方法、生体サンプル解析装置及び生体サンプル解析プログラム |
WO2011125355A1 (fr) * | 2010-04-01 | 2011-10-13 | 株式会社村田製作所 | Procédé de mesure d'une caractéristique d'un objet à mesurer, et dispositif de détection utilisé dans ledit procédé |
JP5859955B2 (ja) * | 2010-04-01 | 2016-02-16 | 株式会社村田製作所 | 被測定物の特性の測定方法、および、それに用いられるセンシングデバイス |
JP2020511652A (ja) * | 2016-12-01 | 2020-04-16 | ユニバーシティ・オブ・ソウル・インダストリー・コーオパレイション・ファウンデイションUniversity Of Seoul Industry Cooperation Foundation | テラヘルツ波を用いたdna分析方法およびdna分析装置 |
CN108398400A (zh) * | 2018-01-18 | 2018-08-14 | 河南工业大学 | 利用太赫兹成像无损检测小麦中脂肪酸含量的方法 |
CN108398400B (zh) * | 2018-01-18 | 2020-12-22 | 河南工业大学 | 利用太赫兹成像无损检测小麦中脂肪酸含量的方法 |
WO2020080576A1 (fr) * | 2018-10-18 | 2020-04-23 | 연세대학교 산학협력단 | Procédé permettant de prédire un changement d'absorbance au moyen d'une interaction intermoléculaire |
CN111366555A (zh) * | 2020-02-27 | 2020-07-03 | 浙江大学 | 一种耕地土壤中农膜残留的检测方法 |
CN111366555B (zh) * | 2020-02-27 | 2021-01-26 | 浙江大学 | 一种耕地土壤中农膜残留的检测方法 |
WO2022029135A1 (fr) * | 2020-08-03 | 2022-02-10 | Jt International Sa | Procédé de mesure et étiquette disposée dans un article à fumer ou un emballage d'articles à fumer |
Also Published As
Publication number | Publication date |
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JPWO2008093647A1 (ja) | 2010-05-20 |
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