WO2008086502A2 - Marqueur moléculaire pour carcinome du rein à cellules claires - Google Patents

Marqueur moléculaire pour carcinome du rein à cellules claires Download PDF

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Publication number
WO2008086502A2
WO2008086502A2 PCT/US2008/050812 US2008050812W WO2008086502A2 WO 2008086502 A2 WO2008086502 A2 WO 2008086502A2 US 2008050812 W US2008050812 W US 2008050812W WO 2008086502 A2 WO2008086502 A2 WO 2008086502A2
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WO
WIPO (PCT)
Prior art keywords
spop
sample
level
patient
protein
Prior art date
Application number
PCT/US2008/050812
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English (en)
Other versions
WO2008086502A3 (fr
Inventor
Kevin P. White
Jiang Liu
Original Assignee
University Of Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Chicago filed Critical University Of Chicago
Publication of WO2008086502A2 publication Critical patent/WO2008086502A2/fr
Publication of WO2008086502A3 publication Critical patent/WO2008086502A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des procédés et compositions pour diagnostiquer, traiter et détecter un carcinome du rein à cellules claires (RCC) chez un patient. Dans certains modes de réalisation, cela implique l'évaluation du taux d'expression SPOP, les taux des transcrits ou bien de protéine SPOP, de manière à déterminer si une cellule rénale est une cellule cancérigène ou tumorale. Dans d'autres modes de réalisation, cela implique d'évaluer si d'autres échantillons biologiques ont un taux élevé de protéine SPOP pour comparaison à un échantillon normal de manière à identifier le RCC chez le patient.
PCT/US2008/050812 2007-01-10 2008-01-10 Marqueur moléculaire pour carcinome du rein à cellules claires WO2008086502A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87966207P 2007-01-10 2007-01-10
US60/879,662 2007-01-10

Publications (2)

Publication Number Publication Date
WO2008086502A2 true WO2008086502A2 (fr) 2008-07-17
WO2008086502A3 WO2008086502A3 (fr) 2008-10-09

Family

ID=39493417

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/050812 WO2008086502A2 (fr) 2007-01-10 2008-01-10 Marqueur moléculaire pour carcinome du rein à cellules claires

Country Status (1)

Country Link
WO (1) WO2008086502A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014185661A1 (fr) * 2013-05-14 2014-11-20 재단법인 의약바이오컨버젼스연구단 Méthode de suivi de métastase de cellules cancéreuses à l'aide de cellules cultivées dans un environnement tridimensionnel de collagène
US10443102B2 (en) 2011-02-24 2019-10-15 Cornell University Recurrent SPOP mutations in prostate cancer
RU2805811C1 (ru) * 2022-06-09 2023-10-24 Федеральное государственное бюджетное учреждение науки Институт теоретической и экспериментальной биофизики Российской академии наук (ИТЭБ РАН) Способ диагностики почечно-клеточной карциномы по наличию зрительных белков аррестина и рековерина в моче

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001032696A2 (fr) * 1999-11-05 2001-05-10 The Burnham Institute Nouvelles proteines de la famille traf
US20040110221A1 (en) * 2002-11-21 2004-06-10 Wyeth Methods for diagnosing RCC and other solid tumors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001032696A2 (fr) * 1999-11-05 2001-05-10 The Burnham Institute Nouvelles proteines de la famille traf
US20040110221A1 (en) * 2002-11-21 2004-06-10 Wyeth Methods for diagnosing RCC and other solid tumors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHOO ET AL: "Testis-specific expression and genomic multiplicity of the rat Rtdpoz genes that encode bipartite TRAF- and POZ/BTB-domain proteins" GENE, ELSEVIER, AMSTERDAM, NL, vol. 387, no. 1-2, 22 December 2006 (2006-12-22), pages 141-149, XP005812497 ISSN: 0378-1119 *
TAKAHASHI I ET AL: "MacroH2A1.2 binds the nuclear protein Spop" BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR CELL RESEARCH, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 1591, no. 1-3, 19 August 2002 (2002-08-19), pages 63-68, XP004377268 ISSN: 0167-4889 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10443102B2 (en) 2011-02-24 2019-10-15 Cornell University Recurrent SPOP mutations in prostate cancer
WO2014185661A1 (fr) * 2013-05-14 2014-11-20 재단법인 의약바이오컨버젼스연구단 Méthode de suivi de métastase de cellules cancéreuses à l'aide de cellules cultivées dans un environnement tridimensionnel de collagène
RU2805811C1 (ru) * 2022-06-09 2023-10-24 Федеральное государственное бюджетное учреждение науки Институт теоретической и экспериментальной биофизики Российской академии наук (ИТЭБ РАН) Способ диагностики почечно-клеточной карциномы по наличию зрительных белков аррестина и рековерина в моче

Also Published As

Publication number Publication date
WO2008086502A3 (fr) 2008-10-09

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