WO2008084864A1 - Capsaicin receptor activator and apparatus for spraying the same - Google Patents

Capsaicin receptor activator and apparatus for spraying the same Download PDF

Info

Publication number
WO2008084864A1
WO2008084864A1 PCT/JP2008/050303 JP2008050303W WO2008084864A1 WO 2008084864 A1 WO2008084864 A1 WO 2008084864A1 JP 2008050303 W JP2008050303 W JP 2008050303W WO 2008084864 A1 WO2008084864 A1 WO 2008084864A1
Authority
WO
WIPO (PCT)
Prior art keywords
capsaicin receptor
receptor activator
activator
capsaicin
spraying
Prior art date
Application number
PCT/JP2008/050303
Other languages
French (fr)
Japanese (ja)
Inventor
Tatsuo Watanabe
Kenji Furuhata
Mitsugu Yamashita
Mie Tsuruga
Original Assignee
Nisshin Pharma Inc.
Daikin Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Pharma Inc., Daikin Industries, Ltd. filed Critical Nisshin Pharma Inc.
Priority to JP2008553130A priority Critical patent/JPWO2008084864A1/en
Publication of WO2008084864A1 publication Critical patent/WO2008084864A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

[PROBLEMS] To provide a capsaicin receptor agonist (activator) having the same various physiological activities as those of capsaicin and has no pungency, and to provide a capsaicin receptor activator which is readily available, is highly safe, shows no adverse side effect even when ingested for a long period, and has high efficacy. [MEANS FOR SOLVING PROBLEMS] Disclosed is a capsaicin receptor activator comprising, as an active ingredient, a monoacylglycerol having a saturated or unsaturated fatty acid having 2 to 22 carbon atoms as a constituent fatty acid.
PCT/JP2008/050303 2007-01-11 2008-01-11 Capsaicin receptor activator and apparatus for spraying the same WO2008084864A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008553130A JPWO2008084864A1 (en) 2007-01-11 2008-01-11 Capsaicin receptor activator and apparatus for spraying the same

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
JP2007003325 2007-01-11
JP2007-003777 2007-01-11
JP2007-003322 2007-01-11
JP2007-003324 2007-01-11
JP2007-003325 2007-01-11
JP2007003321 2007-01-11
JP2007003322 2007-01-11
JP2007-003323 2007-01-11
JP2007003323 2007-01-11
JP2007003777 2007-01-11
JP2007-003321 2007-01-11
JP2007003324 2007-01-11

Publications (1)

Publication Number Publication Date
WO2008084864A1 true WO2008084864A1 (en) 2008-07-17

Family

ID=39608751

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/050303 WO2008084864A1 (en) 2007-01-11 2008-01-11 Capsaicin receptor activator and apparatus for spraying the same

Country Status (2)

Country Link
JP (1) JPWO2008084864A1 (en)
WO (1) WO2008084864A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010270030A (en) * 2009-05-20 2010-12-02 Fukuoka Univ Expression-inducing agent or secretion-promoting agent for antibacterial peptide
EP2445494A1 (en) * 2009-06-24 2012-05-02 Københavns Universitet Treatment of insulin resistance and obesity by stimulating glp-1 release
JP2015124186A (en) * 2013-12-26 2015-07-06 日本メナード化粧品株式会社 Sebum synthesis promoter
WO2018012627A1 (en) * 2016-07-15 2018-01-18 シャープ株式会社 Air blowing apparatus and air conditioner
WO2023112966A1 (en) * 2021-12-14 2023-06-22 ダイキン工業株式会社 Spray device and air treatment device

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6438007A (en) * 1987-04-28 1989-02-08 Lion Corp Skin external preparation
JPS6461421A (en) * 1987-07-06 1989-03-08 Ratsususoon Koore Composition based on phosphatidyl choline and medicinal use
JPH08193028A (en) * 1994-10-04 1996-07-30 Bristol Myers Squibb Co Inhibition of helicobacter
JPH10158124A (en) * 1996-11-25 1998-06-16 Pola Chem Ind Inc Trichogen
JP2001064672A (en) * 1999-08-26 2001-03-13 Kao Corp Body fat combustion promoter
JP2001354558A (en) * 2000-06-12 2001-12-25 Kao Corp Ppar activator
WO2003074043A1 (en) * 2002-03-04 2003-09-12 The Nisshin Oillio Group Ltd. Body temperature elevating agents
JP2003335652A (en) * 2002-05-14 2003-11-25 Yakult Honsha Co Ltd Transglutaminase 1 activator
JP2004292421A (en) * 2003-02-06 2004-10-21 Rinoru Oil Mills Co Ltd Hypertension preventing agent containing conjugated fatty acid as active component and use thereof
JP2005179211A (en) * 2003-12-17 2005-07-07 Idemitsu Kosan Co Ltd External preparation composition for skin
JP2005194222A (en) * 2004-01-06 2005-07-21 Otsuka Pharmaceut Factory Inc Cytokine inducer
WO2005089568A1 (en) * 2004-03-15 2005-09-29 Danisco A/S Emulsifier composition for shortening

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6438007A (en) * 1987-04-28 1989-02-08 Lion Corp Skin external preparation
JPS6461421A (en) * 1987-07-06 1989-03-08 Ratsususoon Koore Composition based on phosphatidyl choline and medicinal use
JPH08193028A (en) * 1994-10-04 1996-07-30 Bristol Myers Squibb Co Inhibition of helicobacter
JPH10158124A (en) * 1996-11-25 1998-06-16 Pola Chem Ind Inc Trichogen
JP2001064672A (en) * 1999-08-26 2001-03-13 Kao Corp Body fat combustion promoter
JP2001354558A (en) * 2000-06-12 2001-12-25 Kao Corp Ppar activator
WO2003074043A1 (en) * 2002-03-04 2003-09-12 The Nisshin Oillio Group Ltd. Body temperature elevating agents
JP2003335652A (en) * 2002-05-14 2003-11-25 Yakult Honsha Co Ltd Transglutaminase 1 activator
JP2004292421A (en) * 2003-02-06 2004-10-21 Rinoru Oil Mills Co Ltd Hypertension preventing agent containing conjugated fatty acid as active component and use thereof
JP2005179211A (en) * 2003-12-17 2005-07-07 Idemitsu Kosan Co Ltd External preparation composition for skin
JP2005194222A (en) * 2004-01-06 2005-07-21 Otsuka Pharmaceut Factory Inc Cytokine inducer
WO2005089568A1 (en) * 2004-03-15 2005-09-29 Danisco A/S Emulsifier composition for shortening

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HOGESTATT E.D. ET AL.: "Cardiovascular pharmacology of anandamide", PROSTAGLANDINS LEUKOTRIENES, AND ESSENTIAL FATTY ACIDS, vol. 66, no. 2-3, 2002, pages 343 - 351 *
WANATABE T. ET AL.: "Shokuhinchu no Capsaicin Juyotai TRPV1 o Kasseika suru Seibun", JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, vol. 127, no. SUPPL. 4, 1 October 2007 (2007-10-01), pages 4 - 6 *
WATANABE T. ET AL.: "Spice ga Inenmaku ni Oyobosu Eikyo", URAKAMI FOUNDATION MEMORIES, vol. 11, 2003, pages 45 - 52 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010270030A (en) * 2009-05-20 2010-12-02 Fukuoka Univ Expression-inducing agent or secretion-promoting agent for antibacterial peptide
EP2445494A1 (en) * 2009-06-24 2012-05-02 Københavns Universitet Treatment of insulin resistance and obesity by stimulating glp-1 release
EP2445494A4 (en) * 2009-06-24 2012-12-12 Univ Koebenhavn Treatment of insulin resistance and obesity by stimulating glp-1 release
JP2015124186A (en) * 2013-12-26 2015-07-06 日本メナード化粧品株式会社 Sebum synthesis promoter
WO2018012627A1 (en) * 2016-07-15 2018-01-18 シャープ株式会社 Air blowing apparatus and air conditioner
WO2023112966A1 (en) * 2021-12-14 2023-06-22 ダイキン工業株式会社 Spray device and air treatment device
JP2023088316A (en) * 2021-12-14 2023-06-26 ダイキン工業株式会社 Spray device and air treatment device
JP7401814B2 (en) 2021-12-14 2023-12-20 ダイキン工業株式会社 Spray equipment and air treatment equipment

Also Published As

Publication number Publication date
JPWO2008084864A1 (en) 2010-05-06

Similar Documents

Publication Publication Date Title
WO2009100441A3 (en) Depot formulations
WO2007117511A3 (en) Feed formulations containing docosahexaenoic acid
HK1131154A1 (en) Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient
WO2011061330A3 (en) Use of physiological cooling active ingredients, and agents containing such active ingredients
WO2006124447A3 (en) Substituted n-arylpyrrolidines as selective androgen receptor modulators
WO2011051354A3 (en) Transdermal pharmaceutical compositions comprising active agents
PT2038290E (en) Modulators of toll-like receptor 7
WO2007061862A3 (en) 2-keto-oxazoles as modulators of fatty acid amide hydrolase
WO2007133637A3 (en) Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
HK1107641A1 (en) Piperidine- and piperazine-1-carboxylic acid amide derivatives and related compounds as modulators of fatty acid amide hydrolase (faah) for the treatment of anxiety, pain and other conditions (faah)- 1-
WO2009082152A3 (en) Glucokinase activators and pharmaceutical compositions containing the same as an active ingredient
WO2007014124A3 (en) High drug load formulations and dosage forms
MX2010004292A (en) Solid dispersion product containing n-aryl urea-based compound.
TW200724166A (en) Wrinkle-improving agent
EP2045253A4 (en) alpha-AMINO ACID DERIVATIVE AND PHARMACEUTICAL COMPRISING THE SAME AS ACTIVE INGREDIENT
WO2008084864A1 (en) Capsaicin receptor activator and apparatus for spraying the same
MX2007003196A (en) Agent and food for preventing/improving functional digestive disorder.
MX2009010675A (en) Pharmaceutical formulations of ghrh molecules.
MX2009005368A (en) Stable parenteral formulation containing a rsv inhibitor of a benzodiazepine structure.
WO2007079180A3 (en) Inhibitors of fatty acid amide hydrolase
WO2009060952A1 (en) Novel preparation
IL174336A0 (en) Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient
PL1795186T3 (en) Flupirtin comprising medicament formulation with a controlled release of the active agent
UA96794C2 (en) Glucocorticoides, method of use thereof, treatment method and pharmaceutical formulation based thereon
WO2007099410A3 (en) Formulations of fispemifene

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08703167

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2008553130

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08703167

Country of ref document: EP

Kind code of ref document: A1